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Sulfated polysaccharides from marine sponges
Sulfated polysaccharides from marine sponges

... with cells from marine sponge in the beginning of the last century (Wilson 1907). This model was based on the observation that dissociated cells from marine sponge go through an aggregation process, in a species-specific way, forming small cellular aggregates. Later, it was observed that this cellul ...
Gastrulation: Making and Shaping Germ Layers
Gastrulation: Making and Shaping Germ Layers

From signal to form: aspects of the cytoskeleton
From signal to form: aspects of the cytoskeleton

... be recorded microscopically in a root hair deformation assay developed for Vicia sativa L. Root hair deformation is a morphogenetic process involving swelling of the hair tip and subsequent new hair outgrowth from that swelling. This response to the signal occurs at a specific developmental stage, n ...
Embryonic activation of the myoD gene is regulated
Embryonic activation of the myoD gene is regulated

... Gene-targeting experiments in mice showed that the elaboration of the myogenic phenotype is dependent on myogenic regulatory gene function. Mice homozygous null for both myoD and myf5 completely lack differentiated skeletal muscle by both histological and biochemical criteria (Rudnicki et al., 1993) ...
CFTR modulates lung secretory cell proliferation and - AJP-Lung
CFTR modulates lung secretory cell proliferation and - AJP-Lung

... suggested that its main function was that of a cAMPregulated chloride channel. Since this discovery, the protein has been shown to have diverse regulatory abilities, yet CF disease pathology is still defined in terms of a lack of a chloride channel. CFTR regulates other secretory channels (12), medi ...
Midgut and muscle development in Drosophila melanogaster
Midgut and muscle development in Drosophila melanogaster

... express genes in a directed fashion. This is achieved by overexpressing the gene of interest in a desired tissue or cell type and analyzing its effects at different developmental stages. This is done by generating transgenic flies expressing a yeast transcriptional activator (GAL4) under the control ...
Linköping University Post Print
Linköping University Post Print

... according to their active site amino acids, into cysteine (cathepsins B, C, F, H, K, L, O, S, V, W, and X), serine (cathepsins A and G), and aspartic cathepsins (cathepsins D and E) [3]. Cell death through apoptosis is tightly controlled by changes in protein expression, proteinprotein interactions, ...
Pre-operative HBO treatment led to enhanced expression of
Pre-operative HBO treatment led to enhanced expression of

... GM3(Neu5Ac), GM3(Neu5Gc), nLc4Cer, GM2(Neu5Ac), and anti-GalNAc-GM1b, with or without permeabilization. Results: All antibodies were capable of labelling of regenerated hepatocytes, predominantly at the cell surface level. The strongest reactivity was observed for GM3(Neu5Gc), equally in all groups ...
Protected Cell Companies Act 1999
Protected Cell Companies Act 1999

Discovery Newsletter Volume7 Winter2011
Discovery Newsletter Volume7 Winter2011

... who were in the Johns Hopkins Hospital Proactive Surveillance Program; 39 of these eventually developed an “unfavorable biopsy,” which means that either the Gleason grade had gotten higher, or the volume of cancer had increased. (In addition to the yearly biopsy, these patients also received a digit ...
1 Electrophysiology and pacemaker function of the - AJP
1 Electrophysiology and pacemaker function of the - AJP

... content of the heart is subject to strong developmental regulation: it is low during initial embryogenesis, and increases during late embryogenesis and postnatal growth (3, 19, 27, 103). After this period of expansion, the proliferation halts but can be triggered by the occurrence of pathological st ...
ASYMMETRIC CELL DIVISION IN PLANTS
ASYMMETRIC CELL DIVISION IN PLANTS

... “mother” cell capable of mating-type switching during the next cell cycle, and a “daughter” cell—which originates as a growing bud on the mother cell—that is not able to switch (Figure 2A). In this way, yeast spores generate cells of two mating types that can subsequently conjugate to produce a dipl ...
Production of fibronectin and collagen types I and III by chick embryo
Production of fibronectin and collagen types I and III by chick embryo

... 10-' 3, 16 and 17) or on collagen antibody binds to an essentiafly extracellular network of rather coarse fibers and patches: in 7-day cultures (Fig. 12), the extracellular antifibronectin-positive network comprises alternatingfy thick strands and thin translucent veil-like meshes. Phase contrast vi ...
Copyright Information of the Article Published Online TITLE Dynamic
Copyright Information of the Article Published Online TITLE Dynamic

... cells or myofibroblasts (MFs). MFs are spindle-shaped cells with stress fibres and welldeveloped fibronexus, and they display α-smooth muscle actin immunohistochemically and smooth-muscle myofilaments ultrastructurally. MFs play a crucial role in physiological and pathological processes. Derived fro ...
PDF - The Corbo Lab
PDF - The Corbo Lab

... include a mouse forkhead homolog, HNF-3β, the zebrafish floating head homeobox gene, and the mouse Brachyury gene (Herrmann et al., 1990; Ang and Rossant, 1994; Weinstein et al., 1994; Talbot et al., 1995). Both Brachyury and HNF-3β are known to be sequence-specific transcription factors (Kispert an ...
NAIP5/NLRC4 Inflammasomes Compounds Inhibit the NLRP1
NAIP5/NLRC4 Inflammasomes Compounds Inhibit the NLRP1

... NaAsO2 and As2O3 inhibit multiple inflammasomes LT-mediated macrophage death requires NLRP1-mediated activation of caspase-1 (18), which normally begins at 50–60 min after toxin treatment (19). Both NaAsO2 (Fig. 2A, left) and As2O3 (Fig. 2A, right) prevented LT-induced caspase-1 autoproteolysis (upp ...
NPR1: the spider in the web of induced resistance signaling pathways
NPR1: the spider in the web of induced resistance signaling pathways

... those that encode PR proteins [1,22]. Besides the direct activation of SA-responsive PR genes, SAR is also associated with an ability to induce cellular defense responses more rapidly or to a greater degree than in non-induced plants. This process, called ‘priming’ [23], leads to the enhanced expres ...
Neuronal polarity: from extracellular signals to
Neuronal polarity: from extracellular signals to

... axon formation to orient asymmetric neuronal growth in Caenorhabditis elegans15. In wild-type C. elegans, the hermaphrodite-specific motorneuron (HSN) extends multiple ventrally directed neurites from its cell body during the third larval stage (L3), and eventually directs a single axon ventrally an ...
Spemann`s organizer and the self-regulation of
Spemann`s organizer and the self-regulation of

Purine nucleosides: endogenous neuroprotectants in hypoxic brain
Purine nucleosides: endogenous neuroprotectants in hypoxic brain

... sine), adenosine kinase (phosphorylates adenosine to 5¢AMP) and nucleoside transporters, are responsible for an extremely short half-life of adenosine in circulation (Fredholm et al. 2001a, 2011; Eltzschig 2009) and therefore some of its effects, are apparently due to its metabolites as was reported ...
Is ATP a Signaling Agent in Plants?
Is ATP a Signaling Agent in Plants?

... found to be stimulated by eATP. Most studies tested eATP in the millimolar range, but it is notable that Venus fly trap closure was accelerated by 100 ␮m eATP (Jaffe, 1973), a concentration consistent with receptor activity (animal P2X receptors may exhibit one-half maximal activation by over 300 ␮m ...
dravhandling-hafte - DUO
dravhandling-hafte - DUO

... Serglycin had been expressed with a green fluorescent protein (GFP) tag at the C-terminus, and for comparison, we chose to make all new variants and model proteins as GFP fusion proteins when expressed in MDCK cells. The glycosaminoglycan (GAG) attachment domain of serglycin was transferred to the j ...
E ect of SB 203580 on the activity of c-Raf in vitro and in vivo
E ect of SB 203580 on the activity of c-Raf in vitro and in vivo

... Pharmaceuticals, Alderley Edge, Maccles®eld, Cheshire SK10 4TG, England ...
Isolation of AtSUC2 promoter-GFP
Isolation of AtSUC2 promoter-GFP

PI3K and Rho GTPase activity are required for exogenous PIP3
PI3K and Rho GTPase activity are required for exogenous PIP3

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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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