Activation of DREAM (Downstream Regulatory
... transmission in LID has been associated with altered redistribution and trafficking of D1Rs (16) along with a massive accumulation of postsynaptic density protein 95 (PSD-95) in the synaptic membrane (17). It has been shown that PSD-95 modulates LID in rats and monkeys by its direct interaction with ...
... transmission in LID has been associated with altered redistribution and trafficking of D1Rs (16) along with a massive accumulation of postsynaptic density protein 95 (PSD-95) in the synaptic membrane (17). It has been shown that PSD-95 modulates LID in rats and monkeys by its direct interaction with ...
Basophils and Autoreactive IgE in the Pathogenesis of
... Lyn is a Src family tyrosine kinase (SFK) that functions to promote or inhibit molecular signals downstream of multiple receptors including cytokine receptors (such as IL-4R or IL-3R), growth factor tyrosine kinase receptors (such as Kit or CD117) or Fc receptors (such as the high affinity IgE recep ...
... Lyn is a Src family tyrosine kinase (SFK) that functions to promote or inhibit molecular signals downstream of multiple receptors including cytokine receptors (such as IL-4R or IL-3R), growth factor tyrosine kinase receptors (such as Kit or CD117) or Fc receptors (such as the high affinity IgE recep ...
A tightly regulated and reversibly inducible siRNA expression
... including small interfering RNA (siRNA) or short hairpin RNA (shRNA) [1,2]. As compared with other gene inhibitory molecules, such as antisense RNAs and oligonucleotides (ODNs), ribozymes and DNAzymes, dsRNAs have apparently become the most powerful and widely used gene silencing reagents for inhibi ...
... including small interfering RNA (siRNA) or short hairpin RNA (shRNA) [1,2]. As compared with other gene inhibitory molecules, such as antisense RNAs and oligonucleotides (ODNs), ribozymes and DNAzymes, dsRNAs have apparently become the most powerful and widely used gene silencing reagents for inhibi ...
Polarity Control of Spindle Positioning in the C. elegans Embryo
... development, a switch to asymmetric division leads to neurogenesis, which peaks around day E14–E15 of mouse embryogenesis and coincides with subtle spindle rotations. Because the apical surface is narrow, even a subtle spindle rotation leads to the creation of a daughter cell that lacks apical surfa ...
... development, a switch to asymmetric division leads to neurogenesis, which peaks around day E14–E15 of mouse embryogenesis and coincides with subtle spindle rotations. Because the apical surface is narrow, even a subtle spindle rotation leads to the creation of a daughter cell that lacks apical surfa ...
- Wiley Online Library
... In yeast and mammalian cells, GFP–PHFAPP1 has been shown to function as a robust in vivo marker for PtdIns4P (Balla et al., 2005; Dowler et al., 2000; Levine and Munro, 2002). To investigate the use of this biosensor in living plant cells, we re-cloned it into a plant vector and expressed it transie ...
... In yeast and mammalian cells, GFP–PHFAPP1 has been shown to function as a robust in vivo marker for PtdIns4P (Balla et al., 2005; Dowler et al., 2000; Levine and Munro, 2002). To investigate the use of this biosensor in living plant cells, we re-cloned it into a plant vector and expressed it transie ...
Job Sharing in the Endomembrane System: Vacuolar
... filled with a central vacuole containing mostly water and solutes that allow plants to maximize collection of solar energy and mineral nutrients by increasing the surface of their photosynthesizing and nutrient-absorbing organs at minimal cost. Besides being lowcost space fillers, vacuoles are the mai ...
... filled with a central vacuole containing mostly water and solutes that allow plants to maximize collection of solar energy and mineral nutrients by increasing the surface of their photosynthesizing and nutrient-absorbing organs at minimal cost. Besides being lowcost space fillers, vacuoles are the mai ...
Polar auxin transport and patterning
... surrounding regions from auxin, thus creating a zone of inhibition that could explain the geometrically highly ordered positioning of primordia. Recently, a series of simulations that derive shoot meristem maxima from polar auxin transport properties has been published in an attempt to explain phyll ...
... surrounding regions from auxin, thus creating a zone of inhibition that could explain the geometrically highly ordered positioning of primordia. Recently, a series of simulations that derive shoot meristem maxima from polar auxin transport properties has been published in an attempt to explain phyll ...
Auxin transport through non-hair cells sustains root
... The plant hormone auxin controls root epidermal cell development in a concentration-dependent manner 1-3. Root hairs are produced on a subset of epidermal cells as they increase in distance from the root tip. Auxin is required for their initiation 4-7 and continued growth 8-11, but little is known a ...
... The plant hormone auxin controls root epidermal cell development in a concentration-dependent manner 1-3. Root hairs are produced on a subset of epidermal cells as they increase in distance from the root tip. Auxin is required for their initiation 4-7 and continued growth 8-11, but little is known a ...
Movement and Remodeling of the Endoplasmic
... Using a novel analytical tool, this study investigates the relative roles of actin, microtubules, myosin, and Golgi bodies on form and movement of the endoplasmic reticulum (ER) in tobacco (Nicotiana tabacum) leaf epidermal cells. Expression of a subset of truncated class XI myosins, which interfere ...
... Using a novel analytical tool, this study investigates the relative roles of actin, microtubules, myosin, and Golgi bodies on form and movement of the endoplasmic reticulum (ER) in tobacco (Nicotiana tabacum) leaf epidermal cells. Expression of a subset of truncated class XI myosins, which interfere ...
Control of the Actin Cytoskeleton in Plant Cell Growth
... nucleation and extension from the barbed end. Paradoxically, fungal and animal formins partially cap the growing barbed end (56, 76, 102), yet in some cases can accelerate monomer incorporation at the barbed end beyond the limits of free diffusion (80). Unlike the putative plant Arp2/3 complex, plan ...
... nucleation and extension from the barbed end. Paradoxically, fungal and animal formins partially cap the growing barbed end (56, 76, 102), yet in some cases can accelerate monomer incorporation at the barbed end beyond the limits of free diffusion (80). Unlike the putative plant Arp2/3 complex, plan ...
Serial killers: ordering caspase activation events in apoptosis
... reviews have detailed how genetic screens for proteins that regulate programmed cell death in C. elegans yielded CED3 ± a cysteine protease with an unusual substrate specificity for Asp residues ± which soon led to the discovery of its mammalian relatives (the caspases).2 Since then, a large number ...
... reviews have detailed how genetic screens for proteins that regulate programmed cell death in C. elegans yielded CED3 ± a cysteine protease with an unusual substrate specificity for Asp residues ± which soon led to the discovery of its mammalian relatives (the caspases).2 Since then, a large number ...
Volume 94, issue 2 July 2011 ...
... understanding of the mechanisms of axonal elongation, quantitative biophysical and imaging methods are needed to analyze the relationship between (1) forces acting on neurons, (2) the bulk movement of cytoskeletal elements/organelles in response to forces, and (3) cytoskeletal assembly/disassembly d ...
... understanding of the mechanisms of axonal elongation, quantitative biophysical and imaging methods are needed to analyze the relationship between (1) forces acting on neurons, (2) the bulk movement of cytoskeletal elements/organelles in response to forces, and (3) cytoskeletal assembly/disassembly d ...
Monitoring Growth of Beer Brewing Strains of
... point to note is that, despite markedly different growth rates, many of the different culture conditions resulted in the same final cell density. This is a finding that an endpoint determination at the end of a long incubation would have missed. The data analysis was simplified by the ability of Gen5™ ...
... point to note is that, despite markedly different growth rates, many of the different culture conditions resulted in the same final cell density. This is a finding that an endpoint determination at the end of a long incubation would have missed. The data analysis was simplified by the ability of Gen5™ ...
A Cell is Like A (100 points) You will compare an animal or plant
... Identify the type of cell (plant or animal) on your poster. Comparison: Write a comparison to show the similarity between the cell organelle and an everyday object/person/place that has a similar function or use as the cell organelle. Be sure to explain the reasoning behind your comparisons. (Fo ...
... Identify the type of cell (plant or animal) on your poster. Comparison: Write a comparison to show the similarity between the cell organelle and an everyday object/person/place that has a similar function or use as the cell organelle. Be sure to explain the reasoning behind your comparisons. (Fo ...
ABA control of plant macroelement membrane transport systems in
... resulted in the enhanced response to ABA in transgenic Arabidopsis plants. Additionally, the AIT1 gene was expressed mainly in vascular tissues, the site of ABA biosynthesis. These results suggest that AIT1 functions in the ABA transport from the vascular system to other parts of the plant. Collecti ...
... resulted in the enhanced response to ABA in transgenic Arabidopsis plants. Additionally, the AIT1 gene was expressed mainly in vascular tissues, the site of ABA biosynthesis. These results suggest that AIT1 functions in the ABA transport from the vascular system to other parts of the plant. Collecti ...
Mechanistic Modeling of Cancer Tumor Growth Using a Porous
... Evading growth suppressors: The genetics of normal cells include genes called tumor suppressors that function to prevent the excessive growth that causes tumor formation. One or more of these growth controls are inactivated cancer cells. Inducing angiogenesis: Malignant cells have triggered the grow ...
... Evading growth suppressors: The genetics of normal cells include genes called tumor suppressors that function to prevent the excessive growth that causes tumor formation. One or more of these growth controls are inactivated cancer cells. Inducing angiogenesis: Malignant cells have triggered the grow ...
Cell Wall, Cytoskeleton, and Cell Expansion in Higher Plants
... from cell wall self-assembly. Although these findings did not take several factors into account, including the incorporation of other wall polymers, turgor-driven expansion, and other biophysical forces, it is clear that microtubules play a primary role in determining the overall pattern of wall arc ...
... from cell wall self-assembly. Although these findings did not take several factors into account, including the incorporation of other wall polymers, turgor-driven expansion, and other biophysical forces, it is clear that microtubules play a primary role in determining the overall pattern of wall arc ...
Direct interaction of FtsZ and MreB is required for septum synthesis
... We also studied a functional fluorescent MreB sandwich fusion encoded by mreB–rfpSW, which had been successfully introduced into the E. coli chromosome by allelic replacement in strain FB76 (Bendezú et al, 2009). MreB–RFPsw showed localisation patterns at mid-cell very similar to those described abo ...
... We also studied a functional fluorescent MreB sandwich fusion encoded by mreB–rfpSW, which had been successfully introduced into the E. coli chromosome by allelic replacement in strain FB76 (Bendezú et al, 2009). MreB–RFPsw showed localisation patterns at mid-cell very similar to those described abo ...
Role of the RNA-binding protein Roquin in immune homeostasis
... range of specificities has the potential to recognize components of the own organism, and several self-tolerance mechanisms have evolved to control the activity of the autoreactive cells. Defects in tolerance pathways have been described in several autoimmune diseases. Systemic lupus erythematosus i ...
... range of specificities has the potential to recognize components of the own organism, and several self-tolerance mechanisms have evolved to control the activity of the autoreactive cells. Defects in tolerance pathways have been described in several autoimmune diseases. Systemic lupus erythematosus i ...
Inhibition of virulence factor expression and swarming differentiation
... invasion of host urothelial cells. The ability to invade urothelial cells is coupled closely to swarming, a form of multicellular behaviour in which vegetative bacteria differentiate into hyper¯agellate, ®lamentous swarming cells capable of co-ordinated and rapid population migration. Co-ordinate ex ...
... invasion of host urothelial cells. The ability to invade urothelial cells is coupled closely to swarming, a form of multicellular behaviour in which vegetative bacteria differentiate into hyper¯agellate, ®lamentous swarming cells capable of co-ordinated and rapid population migration. Co-ordinate ex ...
What is bad in cancer is good in the embryo: Importance of EMT in
... Cadherin 6B during EMT: The loss of Cad6B is directly regulated by transcriptional repression of Snail2 prior to migration of NC in the chick [42]. This was thought to regulate the correct timing of NC emigration and delamination from the neural tube without affecting the expression of the migratory ...
... Cadherin 6B during EMT: The loss of Cad6B is directly regulated by transcriptional repression of Snail2 prior to migration of NC in the chick [42]. This was thought to regulate the correct timing of NC emigration and delamination from the neural tube without affecting the expression of the migratory ...