Answers to Biological Inquiry Questions – Brooker et al ARIS site
Answers to Biological Inquiry Questions – Brooker et al ARIS site

... one cell expresses a high-affinity receptor and another cell a low-affinity receptor, the two cells would respond to the signaling protein at different concentrations. Likewise, the different receptors may be linked with different second messenger molecules generated within the cell. These messenger ...

SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.