Cell-to-cell communication and virulence in Vibrio anguillarum
... quorum-sensing regulator in V. anguillarum. This thesis furthers the knowledge on the quorum-sensing phosphorelay systems in V. anguillarum. In this study, three additional qrr genes were identified, which were expressed during late logarithmic growth phase. The signal synthase VanM activated the ex ...
... quorum-sensing regulator in V. anguillarum. This thesis furthers the knowledge on the quorum-sensing phosphorelay systems in V. anguillarum. In this study, three additional qrr genes were identified, which were expressed during late logarithmic growth phase. The signal synthase VanM activated the ex ...
as a PDF
... fusion proteins (n = 33 cells, 4.1min average duration at 3.85sec intervals) revealed discrete sites of apparent microtubule initiation at the cell cortex (Fig. 1A,B). Microtubules that depolymerized to visible completion rarely showed recovery (48 of 50 events with >2min of imaging after depolymeri ...
... fusion proteins (n = 33 cells, 4.1min average duration at 3.85sec intervals) revealed discrete sites of apparent microtubule initiation at the cell cortex (Fig. 1A,B). Microtubules that depolymerized to visible completion rarely showed recovery (48 of 50 events with >2min of imaging after depolymeri ...
Intracellular calcium: friend or foe?
... permeant ester. Once inside, esterases in the cytoplasm hydrolyse them back to the tetracarboxylate which is now impermeant. From a few micromoles outside, the cell is able to accumulate up to millimolar concentrations of the indicator inside. Though these fluors have now been used widely in many ce ...
... permeant ester. Once inside, esterases in the cytoplasm hydrolyse them back to the tetracarboxylate which is now impermeant. From a few micromoles outside, the cell is able to accumulate up to millimolar concentrations of the indicator inside. Though these fluors have now been used widely in many ce ...
PDF
... subtypes are initially labile and responsive to environmental signals, but become committed shortly before axogenesis (Eisen, 1991), around the time that the alternating pattern of islet2 and islet1 expression is established (Appel et al., 1995). Thus, it was surprising to learn that either Islet1 o ...
... subtypes are initially labile and responsive to environmental signals, but become committed shortly before axogenesis (Eisen, 1991), around the time that the alternating pattern of islet2 and islet1 expression is established (Appel et al., 1995). Thus, it was surprising to learn that either Islet1 o ...
Short Forms of Membrane Receptors: Generation and Role in
... rodents long form of prolactin receptor is generated without the use of exon 11 (termination of translation occurs within exon 10 due to the presence of an internal stopcodon there). During generation of short form of prolactin receptor exon 10 is not used; a sequence from the end of exon 9 up to th ...
... rodents long form of prolactin receptor is generated without the use of exon 11 (termination of translation occurs within exon 10 due to the presence of an internal stopcodon there). During generation of short form of prolactin receptor exon 10 is not used; a sequence from the end of exon 9 up to th ...
The Golgi Apparatus
... lysosomal hydrolases, and lysosome biogenesis; 6. Protein maturation; 7. Sorting and transport of biomolecules to final cellular ...
... lysosomal hydrolases, and lysosome biogenesis; 6. Protein maturation; 7. Sorting and transport of biomolecules to final cellular ...
- Wiley Online Library
... First, an earlier study [17] using transcriptomic profiling of human ESCs and their differentiated progenies identified ZNF281 as one of the upregulated transcriptional regulators in undifferentiated human ESCs. Second, a study of c-Mycassociated proteins in both colorectal cancer cells and human embr ...
... First, an earlier study [17] using transcriptomic profiling of human ESCs and their differentiated progenies identified ZNF281 as one of the upregulated transcriptional regulators in undifferentiated human ESCs. Second, a study of c-Mycassociated proteins in both colorectal cancer cells and human embr ...
E-cadherin controls β-catenin and NF
... 480 cells the activity of the fibronectin and LEF1 promoters was upregulated by co-expression of VP16-Rel (supplementary material Fig. S4), a fusion chimera containing the Rel DNA-binding domain of NF-κB-p65 and the transactivator domain of VP-16. We checked with ChIP experiments whether binding of ...
... 480 cells the activity of the fibronectin and LEF1 promoters was upregulated by co-expression of VP16-Rel (supplementary material Fig. S4), a fusion chimera containing the Rel DNA-binding domain of NF-κB-p65 and the transactivator domain of VP-16. We checked with ChIP experiments whether binding of ...
Possible Involvement of Phosphoinositide-Ca
... neomycin markedly inhibited the PIP 2 -PLC activity associated with rice plasma membranes at more than 50 JIM but did not affect on the PLC activity toward phosphatidylinositol (PI) even at 5 mM. The effect of neomycin on the release of IP 3 from PIP 2 in vivo was examined employing a model experime ...
... neomycin markedly inhibited the PIP 2 -PLC activity associated with rice plasma membranes at more than 50 JIM but did not affect on the PLC activity toward phosphatidylinositol (PI) even at 5 mM. The effect of neomycin on the release of IP 3 from PIP 2 in vivo was examined employing a model experime ...
Full-Text PDF
... 2. A Brief Outline of the Hedgehog Pathway Hh genes are found throughout the animal kingdom. Vertebrates have three hhs: Desert hedgehog (Dhh), Indian hedgehog (Ihh) and Sonic hedgehog (Shh), although Ihh and Shh have undergone duplications in some teleosts [4]. The HH ligand is bound by a large mul ...
... 2. A Brief Outline of the Hedgehog Pathway Hh genes are found throughout the animal kingdom. Vertebrates have three hhs: Desert hedgehog (Dhh), Indian hedgehog (Ihh) and Sonic hedgehog (Shh), although Ihh and Shh have undergone duplications in some teleosts [4]. The HH ligand is bound by a large mul ...
Current Status and Future Prospectives of C1 Domain Ligands as
... ligands have been characterized are mainly based on the proposed role of PKC in the pathophysiology of cancer and AD. In cancer, the differential effects of PKC isoforms on cell proliferation and apoptosis form the basis for targeting PKC. In the central nervous system, PKC regulates processes linke ...
... ligands have been characterized are mainly based on the proposed role of PKC in the pathophysiology of cancer and AD. In cancer, the differential effects of PKC isoforms on cell proliferation and apoptosis form the basis for targeting PKC. In the central nervous system, PKC regulates processes linke ...
REGULATION OF CDC14: PATHWAYS AND CHECKPOINTS OF
... Septation Initiation Network (SIN) (34,35). The SIN was identified by genetic analysis aimed at understanding the control of cytokinesis rather than cyclin degradation and mitotic exit. Surprisingly, SIN does not appear to be required for the activation of APCCdh1. Thus, studies on the two genetic n ...
... Septation Initiation Network (SIN) (34,35). The SIN was identified by genetic analysis aimed at understanding the control of cytokinesis rather than cyclin degradation and mitotic exit. Surprisingly, SIN does not appear to be required for the activation of APCCdh1. Thus, studies on the two genetic n ...
Distinct Protease Requirements for Antigen Presentation In Vitro and
... We were concerned that the emulsification of TTCF in CFA might have partially denatured the protein, thus reducing the dependence on AEP for initial unlocking cleavages. To address this, we immunized mice with two additional forms of the TTCF Ag: TTCF adsorbed onto alum and TTCF expressed within liv ...
... We were concerned that the emulsification of TTCF in CFA might have partially denatured the protein, thus reducing the dependence on AEP for initial unlocking cleavages. To address this, we immunized mice with two additional forms of the TTCF Ag: TTCF adsorbed onto alum and TTCF expressed within liv ...
A Role for the Cytoskeleton in Heart Looping
... basal lamina (see also Fig. 6). MMP-2 is thought to interact within the ECM in the microenvironment to release activating factors that can bind to cell surface receptors, as well as lead to ECM degradation. N-cadherin/βcatenin complex functions in association with connexins and regulates cyclic stre ...
... basal lamina (see also Fig. 6). MMP-2 is thought to interact within the ECM in the microenvironment to release activating factors that can bind to cell surface receptors, as well as lead to ECM degradation. N-cadherin/βcatenin complex functions in association with connexins and regulates cyclic stre ...
Significance of hydrolytic enzymes expressed during xylem
... follows tonoplast rupture and leads to the formation of the hollow conduit. Cell death-associated genes were further observed to be expressed during the emergence of lateral roots in Arabidopsis thaliana. This led to the discovery that cells overlying a lateral root primordium undergo cell death, wh ...
... follows tonoplast rupture and leads to the formation of the hollow conduit. Cell death-associated genes were further observed to be expressed during the emergence of lateral roots in Arabidopsis thaliana. This led to the discovery that cells overlying a lateral root primordium undergo cell death, wh ...
p53 Pathway in Renal Cell Carcinoma Is Repressed by a Dominant
... HeLa (cervical carcinoma), A293 (embryonic kidney epithelial cells transRenal cell carcinoma (RCC) accounts for approximately 85% of all formed with DNA of adenovirus type 5), and LNCaP (prostate adenocarcikidney cancers. Approximately 30,000 patients in the United States noma)] were purchased from ...
... HeLa (cervical carcinoma), A293 (embryonic kidney epithelial cells transRenal cell carcinoma (RCC) accounts for approximately 85% of all formed with DNA of adenovirus type 5), and LNCaP (prostate adenocarcikidney cancers. Approximately 30,000 patients in the United States noma)] were purchased from ...
MICROSCOPIC AND FUNCTIONAL STUDIES ON
... kinases. The activation of above-mentioned enzymes causes inhibition of translocases and phosphatases. This finally enables formation of microvesicle via alterations in cytoskeleton. The fact that platelets are able to produce microvesicles after inhibition of calpain shows that also other pathways ...
... kinases. The activation of above-mentioned enzymes causes inhibition of translocases and phosphatases. This finally enables formation of microvesicle via alterations in cytoskeleton. The fact that platelets are able to produce microvesicles after inhibition of calpain shows that also other pathways ...
Nucleation and Dynamics of Golgi-derived Microtubules
... et al., 2011; Ori-Mckenney et al., 2012; Maia et al., 2013), likely because it can recruit γ-TuRC either directly, or indirectly via CDK5Rap2 or myomegalin interactions. However, AKAP450 function is not essential for MT nucleation at the Golgi in myotubes, likely because γ-TuRC is recruited to the G ...
... et al., 2011; Ori-Mckenney et al., 2012; Maia et al., 2013), likely because it can recruit γ-TuRC either directly, or indirectly via CDK5Rap2 or myomegalin interactions. However, AKAP450 function is not essential for MT nucleation at the Golgi in myotubes, likely because γ-TuRC is recruited to the G ...
PDF - Oxford Academic - Oxford University Press
... plant K+ transport systems (White and Broadley 2000, Zhu and Smolders 2000, Hampton et al. 2004). We therefore decided to investigate whether the ZIFL2 transporter can also influence K+ delivery to the yeast cell, by evaluating its capacity to rescue the deficient growth under limiting K+ supply of ...
... plant K+ transport systems (White and Broadley 2000, Zhu and Smolders 2000, Hampton et al. 2004). We therefore decided to investigate whether the ZIFL2 transporter can also influence K+ delivery to the yeast cell, by evaluating its capacity to rescue the deficient growth under limiting K+ supply of ...
Reciprocal myocardial-endocardial interactions
... were treated for 30 min to confirm the activation of downstream signaling effectors in the myocardium (supplementary material Fig. S1). Following this, hearts were treated for 16 h and conduction ...
... were treated for 30 min to confirm the activation of downstream signaling effectors in the myocardium (supplementary material Fig. S1). Following this, hearts were treated for 16 h and conduction ...
