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Extracellular ATP Functions as an
Extracellular ATP Functions as an

... osmotic stress elicit increased ATP release from Arabidopsis (Jeter et al., 2004), suggesting conservation of ATP release in response to mechanical stimulation between plants and animals. Neuronal cells and secretory cells such as mast cells and pancreatic acinar cells release ATP via regulated exoc ...
Early development of the zebrafish pronephros and analysis of
Early development of the zebrafish pronephros and analysis of

Plasticity in Cell Division Patterns and Auxin
Plasticity in Cell Division Patterns and Auxin

... d Plant Biotechnology Institute, National Research Council of Canada, Saskatoon S7N 0W9, Canada e Molecular and Developmental Genetics, Institute Biology Leiden, Leiden University, 2333 BE Leiden, The Netherlands b Université ...
Role of the OPG/RANK/RANKL triad in calcifications of - HAL
Role of the OPG/RANK/RANKL triad in calcifications of - HAL

... involvement in revascularization of numerous tissues. Thus, OPG induces endothelial colonyforming cell activation and is a positive regulator of microvessel formation in vivo [11]. Similarly, Cross et al also reported a pro-angiogenic effect of OPG which was expressed by tumour endothelial cells [16 ...
Purification, Cloning, and Functional Characterization of a Novel
Purification, Cloning, and Functional Characterization of a Novel

... reaction in macrophages (14 ), to inhibit the replication of hepatitis B virus (15 ), to suppress the invasion of liver cancer cells (7 ) and tumor growth in hepatoma-bearing mice (11 ), to induce cytokine production and increase the population of CD4(+) T cells (16 ), and also to inhibit the infect ...
Sucrose Cleavage Pathways in Aspen Wood
Sucrose Cleavage Pathways in Aspen Wood

... Cellulose is the main component of wood and one of the most important renewable raw materials. In several tree species including Populus species, carbon for cellulose biosynthesis is derived from the disaccharide sucrose. This thesis describes experimental work on the mechanism of sucrose cleavage i ...
Expression of biologically active mouse ciliary neutrophic factor
Expression of biologically active mouse ciliary neutrophic factor

Cell behaviour and cleft palate in the mutant mouse
Cell behaviour and cleft palate in the mutant mouse

... between mutant and normal. The failure of the mutant palate to grow cannot be accounted for on grounds of reduced cell proliferation. For this reason the palatal mesenchyme in 12-5-day and 14-5-day normal and amputated mice has been studied with the scanning electron microscope. This work shows that ...
The regulation and plasticity of root hair patterning
The regulation and plasticity of root hair patterning

... of denser and longer root hairs, lead collectively to an increase in the absorptive area, particularly in the Pi-rich topsoil layer. The coordination of shoot and root responses involves trafficking of systemic signals, such as sugar, microRNAs and hormones, through the vasculature to tune the respo ...
Staphylococcus δ-toxin induces allergic skin disease by
Staphylococcus δ-toxin induces allergic skin disease by

... Atopic dermatitis is a chronic inflammatory skin disease that affects 15–30% of children and approximately 5% of adults in industrialized countries1. Although the pathogenesis of atopic dermatitis is not fully understood, the disease is mediated by an abnormal immunoglobulinE immune response in the ...
1 METT-10, A Putative Methyltransferase, Inhibits Germ
1 METT-10, A Putative Methyltransferase, Inhibits Germ

... phospho-histone-3 (pH3, metaphase marker) nuclei were seen in mett-10(oz36) mutants, indicative of ectopic mitosis (Figure 1D-E). These cells were negative for the meiotic marker, GLD-1 (HANSEN et al. 2004b). Thus, these data argue that the mett-10(oz36) mutation causes proliferation of germ cells w ...
- Wiley Online Library
- Wiley Online Library

... Each plant starts life from the zygote formed by the fusion of an egg and a sperm cell. The zygote gives rise to a multicellular embryo that displays a basic plant body organization and is surrounded by nutritive endosperm and maternal tissue. How the body organization is generated had already been ...
Mesoderm induction: from caps to chips - UNC
Mesoderm induction: from caps to chips - UNC

... Both the Nodal and BMP (bone morphogenetic protein) pathways are activated when a ligand binds a specific heterotetramer that is composed of two type I and two type II receptors, as is the case with all members of the Transforming growth factor-β (TGFB) family. In zebrafish, mutants have been identi ...
letters - Cytomorpholab
letters - Cytomorpholab

Caspary T, Larkins CE, Anderson KV. Dev Cell. 2007 May;12(5):767-78. The graded response to Sonic Hedgehog depends on cilia architecture.
Caspary T, Larkins CE, Anderson KV. Dev Cell. 2007 May;12(5):767-78. The graded response to Sonic Hedgehog depends on cilia architecture.

... of Ptch1-lacZ at the ventral midline was lower than in wildtype embryos, and the domain of Ptch1-lacZ expression extended further dorsally than normal (Figures 1I and 1N). The altered pattern of expression of Ptch-lacZ in hnn mutants indicated that the effective domain of Shh signaling in the neural ...
Mosses as model systems for the study of metabolism and
Mosses as model systems for the study of metabolism and

... unpublished data). Although knockout plants show some retardation of growth, they are still able to utilize sulfate as the sole source of sulfur and it has been proposed that this may be because nitrite reductase, an enzyme of nitrate assimilation, also has sulfite reductase activity (G. Wiedemann, ...
Extra-adrenal glucocorticoids and mineralocorticoids: evidence for
Extra-adrenal glucocorticoids and mineralocorticoids: evidence for

Extra-adrenal glucocorticoids and mineralocorticoids: evidence for
Extra-adrenal glucocorticoids and mineralocorticoids: evidence for

ERK Nuclear Translocation Is Dimerization
ERK Nuclear Translocation Is Dimerization

... located in the cytoplasm of resting cells, although overexpression results in cytoplasmic and nuclear localization (3). It has long been recognized that in the course of physiological signal transduction, ERK accumulates in the nucleus after acute stimulation of the cell (3, 4). Nuclear translocatio ...
Anterior neurectoderm is progressively induced
Anterior neurectoderm is progressively induced

... well as an anterior neural marker, otxA (which is likely to be an alternative genomic copy of Xotx2, described in this report), suggesting that noggin plays a role in patterning anterior neurectoderm (Lamb et al., 1993). In addition to the involvement of extracellular factors in neural patterning, h ...
Developmental stage‐specific expression of Rbm suggests its
Developmental stage‐specific expression of Rbm suggests its

... developmental stages were stained (Figure 2Ba). No speci®c signals were detected in haploid germ cells that were located at the centre of the tubules. Spermatogenesis is initiated shortly after birth. Consequently, the 7 day old testis consists mostly of spermatogonia, while the 9 day old and 17 day ...
Influenza Virus Infections Significant Contribution to Clearance of Fc
Influenza Virus Infections Significant Contribution to Clearance of Fc

... Anesthetized mice were inoculated i.n. with 5 ␮g of H1N1 on day 0 and with either 1 ␮g recombinant murine IL-12 in 1% NMS-PBS or 1% NMSPBS alone on days 0, 1, 2, and 3. The total volume used for each daily i.n. inoculation was 50 ␮l per mouse. Mice were then boosted i.n. with 3 ␮g H1N1 on days 14 an ...
Regulatory Mechanisms of Monofunctional and
Regulatory Mechanisms of Monofunctional and

... tion suffices to achieve chemoprotection, an understanding of the molec ular mechanisms that regulate these enzymes is critical for devising methods for chemoprotection. We report a systematic analysis of the inductions of aryl hydrocarbon hydroxylase (AHH) and NAD(P)H:quinone reducÃ-ase(QR) by seve ...
Effect of Colchicine on Human Tissues.
Effect of Colchicine on Human Tissues.

... Necropsy was performed eight hours after death. Seven and a half centimeters above the anal sphincter was an annular constricting carcinoma which infiltrated the surrounding soft tissues and studded the peritoneum of the recto-vesical fold with metastases. In the cecum and ascending colon were sever ...
Fig. 2a
Fig. 2a

... The M1 macrophage phenotype is induced by interferon-γ (IFN-γ), followed by stimulation with bacterial products such as lipo­polysaccharide (LPS) or by treatment of monocytes with granulocyte-­macrophage colony-stimulating factor (GM-CSF)19–21 (Supplementary Fig. 1a). IRF5 mRNA expression was higher ...
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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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