processing of defensive pigment in aplysia californica: acquisition
... found within the large digestive vacuoles of this cell. storage material and calcium carbonate. Immunogold localization showed that there was a The following model is consistent with our observations: statistically significant occurrence of the red algal red algal rhodoplasts are freed from algal ce ...
... found within the large digestive vacuoles of this cell. storage material and calcium carbonate. Immunogold localization showed that there was a The following model is consistent with our observations: statistically significant occurrence of the red algal red algal rhodoplasts are freed from algal ce ...
The anticancer potential of CITme, a quinoline derivative Sandra Cristina Cardoso Martins
... pharmacological and toxicological tests presented an interesting example of drug research. With support from the UPBRC and the Pharmaceutical Department of North West University, the research began in earnest during March 2007, and the final study was completed on 20 January 2010. I would like to ac ...
... pharmacological and toxicological tests presented an interesting example of drug research. With support from the UPBRC and the Pharmaceutical Department of North West University, the research began in earnest during March 2007, and the final study was completed on 20 January 2010. I would like to ac ...
RCAI Annual Report 2006 (PDF 5.6M)
... rather than competing with the universities, can complement the university research system. What is most significant with RCAI is the focus on young investigators at the beginning of their career. Well over two-thirds of the research laboratories at the Center are lead by young investigators, many o ...
... rather than competing with the universities, can complement the university research system. What is most significant with RCAI is the focus on young investigators at the beginning of their career. Well over two-thirds of the research laboratories at the Center are lead by young investigators, many o ...
Metformin directly acts on mitochondria to alter cellular bioenergetics Open Access
... show that the compound limits respiration and citric acid cycle activity in isolated mitochondria, indicating that at least for these effects, the mitochondrion is the primary target. Finally, we demonstrate that cancer cells exposed to metformin display a greater compensatory increase in aerobic gl ...
... show that the compound limits respiration and citric acid cycle activity in isolated mitochondria, indicating that at least for these effects, the mitochondrion is the primary target. Finally, we demonstrate that cancer cells exposed to metformin display a greater compensatory increase in aerobic gl ...
implementation of medicinal leech preparation to investigate the
... There are forty registered organophosphates in the United States and they range from pesticides and insecticides to nerve agents or neurotoxins such as sarin. Organophosphates (OP’s) have been used in chemical warfare for years and tend to lead to death due to an attack on the nervous system. Chemic ...
... There are forty registered organophosphates in the United States and they range from pesticides and insecticides to nerve agents or neurotoxins such as sarin. Organophosphates (OP’s) have been used in chemical warfare for years and tend to lead to death due to an attack on the nervous system. Chemic ...
Pathogenesis of respiratory infections caused by Mycoplasma dispar
... 1981: Sleigh et al., 1988). This constitutes a highly conserved structure since it was found in all other cilia throughout the animal kingdom (Sleigh, 1977; Sleigh et al., 1988). Claw-like structures have been detected on the tip of the cilia and it was suggested that these structures may play a rol ...
... 1981: Sleigh et al., 1988). This constitutes a highly conserved structure since it was found in all other cilia throughout the animal kingdom (Sleigh, 1977; Sleigh et al., 1988). Claw-like structures have been detected on the tip of the cilia and it was suggested that these structures may play a rol ...
Molecular Regulation of Vascular Cambium Identity and Activity
... “how a stem cell senses to stay as a stem cell and how it knows when to proliferate or differentiate”. The answer lies in the concept of the “stem cell niche”. First postulated by Ray Schofield in 1978 for the haematopoietic stem cells in mammals, stem cell niche can simply be defined as the local m ...
... “how a stem cell senses to stay as a stem cell and how it knows when to proliferate or differentiate”. The answer lies in the concept of the “stem cell niche”. First postulated by Ray Schofield in 1978 for the haematopoietic stem cells in mammals, stem cell niche can simply be defined as the local m ...
Journal of Applied Microbiology
... Methods and Results: Two Aer. veronii mucin- and lactoferrin-binding proteins with molecular masses of 37 and 48 kDa were identified by Western blot analysis. According to its N-terminal amino acid sequence, the 48-kDa protein was identified as Omp48, an outer-membrane protein similar to LamB of Esc ...
... Methods and Results: Two Aer. veronii mucin- and lactoferrin-binding proteins with molecular masses of 37 and 48 kDa were identified by Western blot analysis. According to its N-terminal amino acid sequence, the 48-kDa protein was identified as Omp48, an outer-membrane protein similar to LamB of Esc ...
toxins
... 2.3. Actin cytoskeleton and small GTPases in exocytotic mechanisms Many other proteins play key roles in synaptic vesicle trafficking and priming of tethered synaptic vesicles. Inside nerve terminals, vesicles traffic along actin filaments and this implicates molecular motors like myosins II or V, a ...
... 2.3. Actin cytoskeleton and small GTPases in exocytotic mechanisms Many other proteins play key roles in synaptic vesicle trafficking and priming of tethered synaptic vesicles. Inside nerve terminals, vesicles traffic along actin filaments and this implicates molecular motors like myosins II or V, a ...
year 12 biology - Miss Jan`s Science Wikispace
... Describe how the rate of diffusion is affected by molecule size, temperature, state of matter and conc. Explain what is meant by the surface area to volume ratio Explain how the surface area to volume ratio affects the efficiency of cell transport Explain why cell size is limited by the rate of diff ...
... Describe how the rate of diffusion is affected by molecule size, temperature, state of matter and conc. Explain what is meant by the surface area to volume ratio Explain how the surface area to volume ratio affects the efficiency of cell transport Explain why cell size is limited by the rate of diff ...
Cyclic AMP-Mediated Inhibition of Cell Growth Requires the Small G
... experiments, cells were treated with isoproterenol (10 M), EGF (100 ng/ml), or forskolin (10 M) for 5 min unless otherwise indicated. Where indicated, cells were pretreated with isoproterenol or forskolin for 5 min and then stimulated with EGF for 5 min. H89 (10 M) and PD98059 (10 M) were added ...
... experiments, cells were treated with isoproterenol (10 M), EGF (100 ng/ml), or forskolin (10 M) for 5 min unless otherwise indicated. Where indicated, cells were pretreated with isoproterenol or forskolin for 5 min and then stimulated with EGF for 5 min. H89 (10 M) and PD98059 (10 M) were added ...
The subunit of voltage sensitive Ca 2+ channels is a single
... Abstract The membrane topology of a2/6 subunit was investigated utilizing electrophysiological functional assay and specific anti-a2 antibodies. (a) cRNA encoding a deleted a216 subunit was coinjected with a l C subunit of the L-type calcium channel into Xenopus oocytes. The truncated form, lacking ...
... Abstract The membrane topology of a2/6 subunit was investigated utilizing electrophysiological functional assay and specific anti-a2 antibodies. (a) cRNA encoding a deleted a216 subunit was coinjected with a l C subunit of the L-type calcium channel into Xenopus oocytes. The truncated form, lacking ...
secretory immunoglobulin A triggers distinct intestinal epithelial cell
... microbiota is coated with SIgA [8–10]. Of note, the enzymatic resistance of SIgA to protease-containing secretions such as those present in the gut is enhanced when the antibody is complexed with antigen [11]. Moreover, binding of SIgA to microbiota promotes a controlled sampling of microbial-derive ...
... microbiota is coated with SIgA [8–10]. Of note, the enzymatic resistance of SIgA to protease-containing secretions such as those present in the gut is enhanced when the antibody is complexed with antigen [11]. Moreover, binding of SIgA to microbiota promotes a controlled sampling of microbial-derive ...
Microbiology with basis immunology_1
... Cells that do not have a membrane separating their nuclear material from their cytoplasm are called A. heterozygous. B. homozygous. C. eukaryotic. D. viruses. E. prokaryotic ANSWER: E Why is a bacterium called a prokaryotic organism? A. A bacterium is a one-cell organism that has a distinct nucleus ...
... Cells that do not have a membrane separating their nuclear material from their cytoplasm are called A. heterozygous. B. homozygous. C. eukaryotic. D. viruses. E. prokaryotic ANSWER: E Why is a bacterium called a prokaryotic organism? A. A bacterium is a one-cell organism that has a distinct nucleus ...
Role of the ABC Transporter Ste6 in Cell Fusion during Yeast
... ceil gene was cloned by complementation of the mating defect of the ceil strain, LE4-89, using a CEN-based genomic library (33). A plasmid, pC2-1 containing the STE6 gene, was recovered when retransformed into the original LE4-89 strain was able to restore mating. STE6 Disruption andTagging. A STE6 ...
... ceil gene was cloned by complementation of the mating defect of the ceil strain, LE4-89, using a CEN-based genomic library (33). A plasmid, pC2-1 containing the STE6 gene, was recovered when retransformed into the original LE4-89 strain was able to restore mating. STE6 Disruption andTagging. A STE6 ...
Enzymatic lysis of microbial cells
... in the cell wall, the specific enzyme activation by components present exclusively in the cell wall, and on the specificity in substrate recognition and cell wall binding. Other bacteriolytic enzymes Many other lytic enzymes are able of lysing lysozyme-resistant Gram-positive bacteria. There are: ac ...
... in the cell wall, the specific enzyme activation by components present exclusively in the cell wall, and on the specificity in substrate recognition and cell wall binding. Other bacteriolytic enzymes Many other lytic enzymes are able of lysing lysozyme-resistant Gram-positive bacteria. There are: ac ...
Hopanoids Play a Role in Membrane Integrity and pH
... Construction of an R. palustris shc deletion strain. The shc deletion strain was constructed in R. palustris TIE-1 as previously described (22, 23). Briefly, a deletion plasmid construct, pPVW6, was made by fusing 1 kb of the shc upstream region with 1 kb of the downstream region in the suicide vect ...
... Construction of an R. palustris shc deletion strain. The shc deletion strain was constructed in R. palustris TIE-1 as previously described (22, 23). Briefly, a deletion plasmid construct, pPVW6, was made by fusing 1 kb of the shc upstream region with 1 kb of the downstream region in the suicide vect ...
Role of cancer-associated fibroblasts in breast cancer development
... Fibroblasts are non-vascular, non-epithelial and non-inflammatory cells that form the basic cellular component of connective tissue and contribute to its structural integrity (Tarin, 1969). They play important roles in wound healing, regulation of epithelial differentiation and inflammation (Tomasek ...
... Fibroblasts are non-vascular, non-epithelial and non-inflammatory cells that form the basic cellular component of connective tissue and contribute to its structural integrity (Tarin, 1969). They play important roles in wound healing, regulation of epithelial differentiation and inflammation (Tomasek ...
The unique proline-rich domain of parotid proline
... pLEN expression vector (Neufeld et al., 1987). The signal and propeptide sequences of preproPTH with added 5′ SalI and 3′ HindIII sites were synthesized by PCR, inserted into pBluescript, and the primary structure was confirmed by DNA sequencing. tG cDNA lacking nucleotides encoding a signal sequenc ...
... pLEN expression vector (Neufeld et al., 1987). The signal and propeptide sequences of preproPTH with added 5′ SalI and 3′ HindIII sites were synthesized by PCR, inserted into pBluescript, and the primary structure was confirmed by DNA sequencing. tG cDNA lacking nucleotides encoding a signal sequenc ...
Berberine Enhances Chemosensitivity and Induces Apoptosis
... molecular cancer therapy is more popular up to now, the cytotoxicity chemotherapy for patients with advanced breast cancer is considered as the alternative option. However, chemoresistance is still the common and critical limitation for breast cancer treatment. Berberine, known as AMPK activator, ha ...
... molecular cancer therapy is more popular up to now, the cytotoxicity chemotherapy for patients with advanced breast cancer is considered as the alternative option. However, chemoresistance is still the common and critical limitation for breast cancer treatment. Berberine, known as AMPK activator, ha ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.