
immunoglobulins antigen-antibody reactions and selected tests
... chains into a number of distinct globular domains. The area where the top of the "Y" joins the bottom is called the hinge. This area is flexible to enable the antibody to bind to pairs of epitopes various distances apart on an antigen. The two tips of the "Y" monomer are referred to as the Fab por ...
... chains into a number of distinct globular domains. The area where the top of the "Y" joins the bottom is called the hinge. This area is flexible to enable the antibody to bind to pairs of epitopes various distances apart on an antigen. The two tips of the "Y" monomer are referred to as the Fab por ...
(Hsp90) inhibitors
... Herein we show that the phenotype of Hsp90 knockdown cells using CRISPR technology is significantly different to that generated when cells are treated with classical inhibitors. We reveal that drugs acting via mechanisms unrelated to Hsp90 induce a similar phenotype to that produced by classical Hsp ...
... Herein we show that the phenotype of Hsp90 knockdown cells using CRISPR technology is significantly different to that generated when cells are treated with classical inhibitors. We reveal that drugs acting via mechanisms unrelated to Hsp90 induce a similar phenotype to that produced by classical Hsp ...
Actin behavior in bulk cytoplasm is cell cycle regulated in early
... white line in the schematic on the right-hand side of Fig. 1E) and arranged side-by-side from left to right. This kymograph allowed comparison of nine successive waves of gelation-contraction. Successive waves moved inwards at similar rates (the more vertical the trace, the faster the rate). They sl ...
... white line in the schematic on the right-hand side of Fig. 1E) and arranged side-by-side from left to right. This kymograph allowed comparison of nine successive waves of gelation-contraction. Successive waves moved inwards at similar rates (the more vertical the trace, the faster the rate). They sl ...
Influence of genotype and nutrition on survival and metabolism of starving yeast.
... Hence, an important aspect of chronological aging has gone largely unnoticed so far: Yeast viability depends on which nutrient is limited first. Therefore, it seems clear that rigorous control of conditions is required while studying chronological aging specifically because gene effects previously f ...
... Hence, an important aspect of chronological aging has gone largely unnoticed so far: Yeast viability depends on which nutrient is limited first. Therefore, it seems clear that rigorous control of conditions is required while studying chronological aging specifically because gene effects previously f ...
Acanthamoeba polyphaga Intracellular Infection of
... tightly closed around the bacteria, similar to what has been ...
... tightly closed around the bacteria, similar to what has been ...
Newport Biologics Catalog
... Newport Biologics Resorbable Collagen Membrane 4-6 is a white, nonfriable, conformable membrane matrix engineered from highly purified type I collagen derived from porcine tendon. This membrane was developed with the thickness, density, permeability, mechanical strength, and in vivo stability proper ...
... Newport Biologics Resorbable Collagen Membrane 4-6 is a white, nonfriable, conformable membrane matrix engineered from highly purified type I collagen derived from porcine tendon. This membrane was developed with the thickness, density, permeability, mechanical strength, and in vivo stability proper ...
Effect of n-butanol and cold pretreatment on the cytoskeleton and
... Production of double haploid (DH) plants is a valuable tool in conventional breeding. This technique reduces the time needed for the development of new, improved varieties. Developing microspores of higher plants possess the ability to switch their default gametophytic developmental program to the s ...
... Production of double haploid (DH) plants is a valuable tool in conventional breeding. This technique reduces the time needed for the development of new, improved varieties. Developing microspores of higher plants possess the ability to switch their default gametophytic developmental program to the s ...
Human red blood cells-1 - Science Publishing Group
... Adriano Sturli (1873-1964) identified the fourth blood ...
... Adriano Sturli (1873-1964) identified the fourth blood ...
Section 2: Energy Flow in Ecosystems
... Groups of Sponges, continued • The skeleton of most sponges is comprised of tiny needles made of silica or calcium called spicules. • A few sponges have a skeleton composed of a resilient, flexible protein fiber called spongin. • Modern sponges are classified according to the composition of the skel ...
... Groups of Sponges, continued • The skeleton of most sponges is comprised of tiny needles made of silica or calcium called spicules. • A few sponges have a skeleton composed of a resilient, flexible protein fiber called spongin. • Modern sponges are classified according to the composition of the skel ...
Influence of Notch on dorsoventral
... By contrast, we have proposed a completely different model, in which Notch activation does not influence compartmentalization by contributing to dorsal- or ventral-type cell affinities, but rather creates a fence (Irvine and Rauskolb, 2001; Rauskolb et al., 1999), which we define as a property or be ...
... By contrast, we have proposed a completely different model, in which Notch activation does not influence compartmentalization by contributing to dorsal- or ventral-type cell affinities, but rather creates a fence (Irvine and Rauskolb, 2001; Rauskolb et al., 1999), which we define as a property or be ...
The Pathogenic Fungus Paracoccidioides brasiliensis Exports
... debris (33). In C. neoformans, membranous vesicles carry glucuronoxylomannan (GXM), the major capsular polysaccharide, to the extracellular space. The polysaccharide is then released and reincorporated into the cell surface as a parallel mechanism of capsule growth (32, 33, 42). Vesicles containing ...
... debris (33). In C. neoformans, membranous vesicles carry glucuronoxylomannan (GXM), the major capsular polysaccharide, to the extracellular space. The polysaccharide is then released and reincorporated into the cell surface as a parallel mechanism of capsule growth (32, 33, 42). Vesicles containing ...
Plant Cytokinesis Is Orchestrated by the Sequential Action of the
... Brief Overlap at the Onset and End of Cytokinesis We first set out to elucidate the localization dynamics of TRAPPII and exocyst subunits throughout cytokinesis. CLUB/AtTRS130 and AtTRS120 GFP fusions, expressed under the control of ubiquitin and/or native promoters, were shown to be functional (Fig ...
... Brief Overlap at the Onset and End of Cytokinesis We first set out to elucidate the localization dynamics of TRAPPII and exocyst subunits throughout cytokinesis. CLUB/AtTRS130 and AtTRS120 GFP fusions, expressed under the control of ubiquitin and/or native promoters, were shown to be functional (Fig ...
Photoactivation of GFP reveals protein dynamics within the
... Measurement of the rate at which activated GFP moves away from the activation spot shows that this motion is much faster than would be expected if membrane components moved simply by diffusion. Treatment with latrunculin to depolymerize the actin cytoskeleton stops ER remodelling and reduces the rat ...
... Measurement of the rate at which activated GFP moves away from the activation spot shows that this motion is much faster than would be expected if membrane components moved simply by diffusion. Treatment with latrunculin to depolymerize the actin cytoskeleton stops ER remodelling and reduces the rat ...
Although ABA is mainly made in the leaves and the root cap, all
... microinjected cADPR induced ABA-inducible gene expression that can be abolished by EGTA treatment (Wu et al., 1997). IP3 involvement was also implicated by the observation that AtPLC1 (phospholipase C) gene is ABA-inducible (Hirayama et al., 1995). IP3 was shown to cause cytosolic Ca2+ increase and ...
... microinjected cADPR induced ABA-inducible gene expression that can be abolished by EGTA treatment (Wu et al., 1997). IP3 involvement was also implicated by the observation that AtPLC1 (phospholipase C) gene is ABA-inducible (Hirayama et al., 1995). IP3 was shown to cause cytosolic Ca2+ increase and ...
A High-Resolution Transcript Profile across the
... sections can only be determined after sampling. It is thus nearly impossible to obtain two series that overlap perfectly so that corresponding sections contain exactly the same cell type. The result of this variation in sampling and biology is that for a gene with the same tissue-specific expression ...
... sections can only be determined after sampling. It is thus nearly impossible to obtain two series that overlap perfectly so that corresponding sections contain exactly the same cell type. The result of this variation in sampling and biology is that for a gene with the same tissue-specific expression ...
Imaging the fate of histone Cse4 reveals de novo replacement in S
... Unstructured N-terminal tail (aa1-135) is depicted in grey while region corresponding to the known 3D structure of mammalian CENP-A (aa134-226) is shown as solid black and red (loops and α-helices of histone-fold domain). Functionally important END region (aa28-60) and C-terminal CENP–C interaction ...
... Unstructured N-terminal tail (aa1-135) is depicted in grey while region corresponding to the known 3D structure of mammalian CENP-A (aa134-226) is shown as solid black and red (loops and α-helices of histone-fold domain). Functionally important END region (aa28-60) and C-terminal CENP–C interaction ...
SOMBRERO, BEARSKIN1, and BEARSKIN2 Regulate Root Cap
... layers. In the smb-3 mutant, there therefore seems to be a failure of the maturing LRC cells to cease dividing and complete maturation by the time they occupy the usual position of the mature LRC cell file. Furthermore, the cells previously in the mature position in smb-3 fail to detach from the roo ...
... layers. In the smb-3 mutant, there therefore seems to be a failure of the maturing LRC cells to cease dividing and complete maturation by the time they occupy the usual position of the mature LRC cell file. Furthermore, the cells previously in the mature position in smb-3 fail to detach from the roo ...
pptx
... reflective of the inhibitory effect of metformin on energydependent transport of 2DG concentrations not high enough to recruit GLUT 2 transporters. ...
... reflective of the inhibitory effect of metformin on energydependent transport of 2DG concentrations not high enough to recruit GLUT 2 transporters. ...
Det här verket är upphovrättskyddat enligt Lagen (1960
... cells, into the follicle lumen. In its earliest stage the pseudopod has the appearance of a longitudinal fold. This fold curies, its margins fuse and a double-walled tube, open at the top, is formed. The tube is then closed and the pseudopod is transformed into a cystlike or more irregular structure ...
... cells, into the follicle lumen. In its earliest stage the pseudopod has the appearance of a longitudinal fold. This fold curies, its margins fuse and a double-walled tube, open at the top, is formed. The tube is then closed and the pseudopod is transformed into a cystlike or more irregular structure ...
A Critical Role for Egr-1 Characterization of CD44 Induction by IL-1:
... have been reported (10, 11), which are generated by alternative usage of amino acid sequences encoded by 10 variant exons (termed v1-v10) (12). CD44 variant isoform expression was initially believed to occur as a result of aberrant splicing in tumor cells; however, variant expression has subsequentl ...
... have been reported (10, 11), which are generated by alternative usage of amino acid sequences encoded by 10 variant exons (termed v1-v10) (12). CD44 variant isoform expression was initially believed to occur as a result of aberrant splicing in tumor cells; however, variant expression has subsequentl ...
p.1 MicroRNA miR-144 modulates oxidative stress
... expression seen between these two groups, we compared the mean expression of 83 previously defined reticulocyte-enriched microRNAs26 in each group (Supplemental Figure 1) and found no significant differences (Figure 1B). This result indicates that the expression differences between the two HbSS grou ...
... expression seen between these two groups, we compared the mean expression of 83 previously defined reticulocyte-enriched microRNAs26 in each group (Supplemental Figure 1) and found no significant differences (Figure 1B). This result indicates that the expression differences between the two HbSS grou ...
Research Paper Role of Particle Size in Phagocytosis of Polymeric
... phagocytosis by macrophages. Although numerous studies have reported on the biochemical pathways of phagocytosis, relatively little is known about the dependence of phagocytosis on particle size. Here, we investigate the previously unexplained dependence of phagocytosis on particle size. Methods. Ra ...
... phagocytosis by macrophages. Although numerous studies have reported on the biochemical pathways of phagocytosis, relatively little is known about the dependence of phagocytosis on particle size. Here, we investigate the previously unexplained dependence of phagocytosis on particle size. Methods. Ra ...
Cell encapsulation

Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.