
Analysis of acquired resistance to metronomic oral
... direct targeting of activated endothelial cells in the tumor neovasculature [7, 8] as well as blockade of mobilization of pro-angiogenic/vasculogenic bone-marrow derived cell (BMDC) populations (e.g. circulating endothelial progenitor cells) have both been implicated [9, 10]. Suppression of HIF-1α m ...
... direct targeting of activated endothelial cells in the tumor neovasculature [7, 8] as well as blockade of mobilization of pro-angiogenic/vasculogenic bone-marrow derived cell (BMDC) populations (e.g. circulating endothelial progenitor cells) have both been implicated [9, 10]. Suppression of HIF-1α m ...
PDF - The Journal of Immunology
... genotyping are shown (left panel ). rES cells were genotyped by PCR using Lox1/SDL2 primers and identified on the basis of the appearance of a doublet band of 325/263 bp (right panel ). (B) Confirmation of the presence of conditional null allele in rES cells. rES cells were infected by Ad-CMV-Cre (V ...
... genotyping are shown (left panel ). rES cells were genotyped by PCR using Lox1/SDL2 primers and identified on the basis of the appearance of a doublet band of 325/263 bp (right panel ). (B) Confirmation of the presence of conditional null allele in rES cells. rES cells were infected by Ad-CMV-Cre (V ...
Inflammation Protein L13a in Macrophages Resolves An
... genotyping are shown (left panel). rES cells were genotyped by PCR using Lox1/SDL2 primers and identified on the basis of the appearance of a doublet band of 325/263 bp (right panel). (B) Confirmation of the presence of conditional null allele in rES cells. rES cells were infected by Ad-CMV-Cre (Vec ...
... genotyping are shown (left panel). rES cells were genotyped by PCR using Lox1/SDL2 primers and identified on the basis of the appearance of a doublet band of 325/263 bp (right panel). (B) Confirmation of the presence of conditional null allele in rES cells. rES cells were infected by Ad-CMV-Cre (Vec ...
Only a subset of the binary cell fate decisions
... The numbSW allele was isolated through an F1 revertant screen of the P-element-induced numb1 allele. Dysgenic males of the genotype numb1 /CyO; Dr ∆ 2-3/+ were crossed to numb2 pr cn Elp/CyO females. The F1 Cy+ progeny were collected and examined for abnormal sensory bristle phenotypes on the fly no ...
... The numbSW allele was isolated through an F1 revertant screen of the P-element-induced numb1 allele. Dysgenic males of the genotype numb1 /CyO; Dr ∆ 2-3/+ were crossed to numb2 pr cn Elp/CyO females. The F1 Cy+ progeny were collected and examined for abnormal sensory bristle phenotypes on the fly no ...
Development
... 4888 H. R. M. Schlaman and others embryogenesis can be rescued either by the addition of rhizobial LCOs or by an endochitinase purified from wild-type embryos (de Jong et al., 1993). (3) Tobacco plants transgenic for Rhizobium nodA and/or nodB, which are involved in LCO production, are severely aff ...
... 4888 H. R. M. Schlaman and others embryogenesis can be rescued either by the addition of rhizobial LCOs or by an endochitinase purified from wild-type embryos (de Jong et al., 1993). (3) Tobacco plants transgenic for Rhizobium nodA and/or nodB, which are involved in LCO production, are severely aff ...
A Flow Cytometry Approach to Detect In vivo Chromatin Compaction
... versus log height of green fluorescence, was used as a quantitative measure for the chromatin condensation a. This procedure was conducted as follows: on a scatter gram of red versus green fluorescence, region 2 (R2) was designed by drawing a polygon to include the majority protoplast from R1, excludi ...
... versus log height of green fluorescence, was used as a quantitative measure for the chromatin condensation a. This procedure was conducted as follows: on a scatter gram of red versus green fluorescence, region 2 (R2) was designed by drawing a polygon to include the majority protoplast from R1, excludi ...
The ventral and posterior expression of the zebrafish homeobox
... lution allows the formation of two layers: the epiblast (composed of cells that have not involuted) and the hypoblast (made of cells that have involuted), whose embryological derivatives are ectoderm and endo/mesoderm, respectively. All these features reinforce the concept of unitary mechanisms in t ...
... lution allows the formation of two layers: the epiblast (composed of cells that have not involuted) and the hypoblast (made of cells that have involuted), whose embryological derivatives are ectoderm and endo/mesoderm, respectively. All these features reinforce the concept of unitary mechanisms in t ...
Multiple post-translational modifications regulate E
... to WGA agarose. As expected, treatment with TN prevented Nlinked glycosylation of E-cadherin and therefore decreased the molecular mass of the mature protein (Fig. 1A, lane 2, N). Although TN treatment abolished the binding of 120 kDa Ecadherin (Fig. 1A, lane 2, m) to WGA, a substantial fraction of ...
... to WGA agarose. As expected, treatment with TN prevented Nlinked glycosylation of E-cadherin and therefore decreased the molecular mass of the mature protein (Fig. 1A, lane 2, N). Although TN treatment abolished the binding of 120 kDa Ecadherin (Fig. 1A, lane 2, m) to WGA, a substantial fraction of ...
Full Text - The International Journal of Developmental Biology
... Fig. 3 (Left). Expression of IoN-Dl pathway components during the early cleavage stages. (A) IoN: At the 2q stage, all cells in the embryo have a low level of cytoplasmic expression. 2q cells have slightly stronger cytoplasmic expression. All cells in the embryo, with the exception of 1q cells, have ...
... Fig. 3 (Left). Expression of IoN-Dl pathway components during the early cleavage stages. (A) IoN: At the 2q stage, all cells in the embryo have a low level of cytoplasmic expression. 2q cells have slightly stronger cytoplasmic expression. All cells in the embryo, with the exception of 1q cells, have ...
Leaf growth in grasses is determined by the cell division and
... both treatments. The cell division rate at the leaf base was about 8 and 5 cells mm-1 h-1 for the control and saline treatments, respectively. As such, salinity significantly reduced the cell division rate by about 30% within the initial 1–2 mm above the base. In tall fescue, epidermal cell division ...
... both treatments. The cell division rate at the leaf base was about 8 and 5 cells mm-1 h-1 for the control and saline treatments, respectively. As such, salinity significantly reduced the cell division rate by about 30% within the initial 1–2 mm above the base. In tall fescue, epidermal cell division ...
Materials - HAL
... (PTK) and protein tyrosine phosphatase (PTP) activities (for a review, see Neel and Tonks, 1997). Since any misregulation can lead to severe disease, these activities must be tightly regulated (Hunter, 1997; Zhang, 2001). Relatively little is known about the function and regulation of PTPs. Like for ...
... (PTK) and protein tyrosine phosphatase (PTP) activities (for a review, see Neel and Tonks, 1997). Since any misregulation can lead to severe disease, these activities must be tightly regulated (Hunter, 1997; Zhang, 2001). Relatively little is known about the function and regulation of PTPs. Like for ...
Shifts, Aneuploidy, and Loss of Heterozygosity Rapid Mechanisms
... allows unmasking of these mutations, enhancing overall fitness. Parasex, and its ability to mediate changes in ploidy, can therefore promote adaptation even in the absence of a conventional sexual program. C. albicans, the most prevalent human pathogen, also possesses a parasexual mating program. Th ...
... allows unmasking of these mutations, enhancing overall fitness. Parasex, and its ability to mediate changes in ploidy, can therefore promote adaptation even in the absence of a conventional sexual program. C. albicans, the most prevalent human pathogen, also possesses a parasexual mating program. Th ...
Control of pathfinding by the avian trunk neural crest
... the sclerotome has dispersed. Finally, other neural crest cells may enter the sclerotome by migrating along the ventral root motor fibres that also course through the anterior somite (see below). Some of the crest cells migrate between the neural tube and somite opposite the posterior half of a somi ...
... the sclerotome has dispersed. Finally, other neural crest cells may enter the sclerotome by migrating along the ventral root motor fibres that also course through the anterior somite (see below). Some of the crest cells migrate between the neural tube and somite opposite the posterior half of a somi ...
PDF - Bentham Open
... Institute of Genomics and Integrative Biology, New Delhi, India. Uptake of BIO-11006 by Normal Human Bronchial ...
... Institute of Genomics and Integrative Biology, New Delhi, India. Uptake of BIO-11006 by Normal Human Bronchial ...
The impact of abiotic factors on cellulose synthesis
... both biotic and abiotic factors. One of the most common plant adaptations to environmental changes is differential regulation of growth, which results in growth either away from adverse conditions or towards more favorable conditions. As cell walls shape plant growth, this differential growth respon ...
... both biotic and abiotic factors. One of the most common plant adaptations to environmental changes is differential regulation of growth, which results in growth either away from adverse conditions or towards more favorable conditions. As cell walls shape plant growth, this differential growth respon ...
Cell Wall, Cytoskeleton, and Cell Expansion in Higher Plants
... key players between cellulose synthase complexes and microtubules. The authors apologize to many colleagues whose work could not be cited because of space limitations. ...
... key players between cellulose synthase complexes and microtubules. The authors apologize to many colleagues whose work could not be cited because of space limitations. ...
effects of disease-causing mutations associated with five
... submission of the final copies of the dissertation to the Graduate College. I hereby certify that I have read this dissertation prepared under my direction and recommend that it be accepted as fulfilling the dissertation requirement. ...
... submission of the final copies of the dissertation to the Graduate College. I hereby certify that I have read this dissertation prepared under my direction and recommend that it be accepted as fulfilling the dissertation requirement. ...
Actin Dynamics in Papilla Cells of Brassica rapa
... test this hypothesis, we examined the effects of CD, an actin-depolymerizing drug, on pollination. For this experiment, pistils were excised and the cutting edge was soaked in a solution containing 100 mM CD for 4 h. Following fixation, pistils were stained with rhodaminephalloidin. We detected prom ...
... test this hypothesis, we examined the effects of CD, an actin-depolymerizing drug, on pollination. For this experiment, pistils were excised and the cutting edge was soaked in a solution containing 100 mM CD for 4 h. Following fixation, pistils were stained with rhodaminephalloidin. We detected prom ...
+Tec - Blood Journal
... of experiment as in (AI were performedin BaF3 cells. The positions of molecular weight standards are shown at theleft (xlo-’)). (C) 32D cells (1 x lo7 cellslexperiment) were starved of IL-3 overnight and restimulated with IL-3 (100 UlmL) for 0, 1, 5, 10, or 20 minutes as indicated at the top. Tec wa ...
... of experiment as in (AI were performedin BaF3 cells. The positions of molecular weight standards are shown at theleft (xlo-’)). (C) 32D cells (1 x lo7 cellslexperiment) were starved of IL-3 overnight and restimulated with IL-3 (100 UlmL) for 0, 1, 5, 10, or 20 minutes as indicated at the top. Tec wa ...
Short-Lived and Phosphorylated Proteins
... that the efflux carrier in plants constitutes a complex system regulated at multiple levels, in marked contrast with the influx carrier. Physiological implications of the kinetic features of this regulation are discussed. ...
... that the efflux carrier in plants constitutes a complex system regulated at multiple levels, in marked contrast with the influx carrier. Physiological implications of the kinetic features of this regulation are discussed. ...
Cloning, Expression, and Functional Characterization of TL1A-Ig
... Ligation to antigen causes B cells to proliferate and differentiate into effector plasma cells that produce antibodies, while T cells recognize antigen presented by APCs activate and differentiate into one of the effector cell subsets involved in killing (cytotoxic T cells), activation (helper T cel ...
... Ligation to antigen causes B cells to proliferate and differentiate into effector plasma cells that produce antibodies, while T cells recognize antigen presented by APCs activate and differentiate into one of the effector cell subsets involved in killing (cytotoxic T cells), activation (helper T cel ...
collection fact sheet
... Collagen protein is the natural solution for “beautiful skin” and is one of the critical components in maintaining the elasticity of the skin. The main structural component of the lower layer of the skin (Dermis) is a protein called collagen. Bundles of collagen molecules pack together throughout th ...
... Collagen protein is the natural solution for “beautiful skin” and is one of the critical components in maintaining the elasticity of the skin. The main structural component of the lower layer of the skin (Dermis) is a protein called collagen. Bundles of collagen molecules pack together throughout th ...
Cell encapsulation

Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.