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Bio Frames - Lee County School District
Bio Frames - Lee County School District

... focuses on how teachers can help students develop a more thorough understanding of informa on associated with key topics and main ideas. The Biology Frames can be used in many ways. Some instructors using the Framing Rou ne in their classrooms with students, will already have the model frame complet ...
Molecular Regulation of Vascular Cambium Identity and Activity
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... their animal counterparts are reservoirs of cells that can both produce new cells for the generation of new tissues and organs, and self-maintain indeterminately via asymmetric cell division. The asymmetric division of an initial cell generates two daughter cells; one remains as an undifferentiated ...
CHARACTERIZATION OF MOLECULES SHOWING
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... should therefore be an evolutionary dead end. However, accumulating evidence for at least occasional biparental transmission (or paternal leakage) provides opportunities for sporadic sexual recombination events between organellar genomes. Those could significantly slow down Muller’s ratchet, but the ...
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Electron Microscope Observations of Brucella abortus
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Emerging biological roles of Cl− intracellular channel proteins
Emerging biological roles of Cl− intracellular channel proteins

... Rho-regulated cortical actin dynamics as well as vesicular trafficking and integrin recycling, the latter of which are under the control of Rab GTPases. In this Commentary, we discuss the emerging roles of CLIC proteins in these processes and the lessons learned from genetargeting studies. We also h ...
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KLF4 N-Terminal Variance Modulates Induced Reprogramming to

... As the quintessential reprogramming model, OCT3/4, SOX2, KLF4, and c-MYC re-wire somatic cells to achieve induced pluripotency. Yet, subtle differences in methodology confound comparative studies of reprogramming mechanisms. Employing transposons, we systematically assessed cellular and molecular ha ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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