Targets for breast cancer diagnosis and treatment
... back into the chromosome (Alitalo et al.). As a result. 50 or ...
... back into the chromosome (Alitalo et al.). As a result. 50 or ...
Isolation of Spherosomes with Lysosome Characteristics from
... nents from the soluble material indicates the pos sibility of an interaction between hydrolases and soluble factors. In fact the high speed supernatant contains an inhibitory factor for acid protease and phosphatase as demonstrated by determ inations of sedimentable activities in the presence or ab ...
... nents from the soluble material indicates the pos sibility of an interaction between hydrolases and soluble factors. In fact the high speed supernatant contains an inhibitory factor for acid protease and phosphatase as demonstrated by determ inations of sedimentable activities in the presence or ab ...
Isolation of Spherosomes with Lysosome
... nents from the soluble material indicates the pos sibility of an interaction between hydrolases and soluble factors. In fact the high speed supernatant contains an inhibitory factor for acid protease and phosphatase as demonstrated by determ inations of sedimentable activities in the presence or ab ...
... nents from the soluble material indicates the pos sibility of an interaction between hydrolases and soluble factors. In fact the high speed supernatant contains an inhibitory factor for acid protease and phosphatase as demonstrated by determ inations of sedimentable activities in the presence or ab ...
Differential role played by the MEK/ERK/EGR
... as a DNA-binding domain, which binds to the consensus, GC-rich, DNA sequence 5 -GCG(G/T)GGGCG-3 [11] and a transcription activation/repression domain, consistent with the diverse activities associated with the molecule [25,26]. Its activation moiety is equipped with three C2 H2 zinc fingers, chara ...
... as a DNA-binding domain, which binds to the consensus, GC-rich, DNA sequence 5 -GCG(G/T)GGGCG-3 [11] and a transcription activation/repression domain, consistent with the diverse activities associated with the molecule [25,26]. Its activation moiety is equipped with three C2 H2 zinc fingers, chara ...
Host Pathogen Interaction at the Plant Cell Wall
... groups during catalysis, whereas lyases have basic pH optima, using catalytic amino acids that are still under active investigation (Herron et al., 2000). In certain pathogens, such as Erwinia chrysanthemi, the genetic organization and regulation of many secretory saccharidases have been elucidated ...
... groups during catalysis, whereas lyases have basic pH optima, using catalytic amino acids that are still under active investigation (Herron et al., 2000). In certain pathogens, such as Erwinia chrysanthemi, the genetic organization and regulation of many secretory saccharidases have been elucidated ...
A myosin inhibitor impairs auxin
... day 8. During the second phase of the culture cycle, the frequency of unicellular files gradually recovers to the initial situation. At day 8, the majority of files consists of four or more cells. These files disintegrate subsequently, causing the recovery in the frequency of singular cells. In the ...
... day 8. During the second phase of the culture cycle, the frequency of unicellular files gradually recovers to the initial situation. At day 8, the majority of files consists of four or more cells. These files disintegrate subsequently, causing the recovery in the frequency of singular cells. In the ...
Antigen-Antibody Properties
... Antigen-Antibody Properties • You must remember Antibody affinity (single) VS avidity (multiple) • Cross-reactivity: occurs when two different antigens share an identical or very similar epitope. The antibody’s affinity for the cross-reacting epitope will be _____ than for the original epitope. • A ...
... Antigen-Antibody Properties • You must remember Antibody affinity (single) VS avidity (multiple) • Cross-reactivity: occurs when two different antigens share an identical or very similar epitope. The antibody’s affinity for the cross-reacting epitope will be _____ than for the original epitope. • A ...
a comparative cytological and morphometric analysis of vacuolation
... Vacuoles play very important physiological roles in plant cells. Pea root nodules, which exhibit distinct zonation (meristematic zone and central tissue zones), may serve as a good experimental model for the investigations of vacuole development and its importance to cell and tissue functioning. Mor ...
... Vacuoles play very important physiological roles in plant cells. Pea root nodules, which exhibit distinct zonation (meristematic zone and central tissue zones), may serve as a good experimental model for the investigations of vacuole development and its importance to cell and tissue functioning. Mor ...
Origin, Early Patterning, and Fate of the Mouse Epiblast
... reach its blastocoelic surface. The authors propose that Dab2mutant PrE cells fail to respond to extracellular cues normally involved in positioning them. Interestingly, embryos mutant for γ1-laminin, which cannot assemble a basal lamina, have a similar phenotype.28 MOLECULAR CONTROL OF PLURIPOTENTI ...
... reach its blastocoelic surface. The authors propose that Dab2mutant PrE cells fail to respond to extracellular cues normally involved in positioning them. Interestingly, embryos mutant for γ1-laminin, which cannot assemble a basal lamina, have a similar phenotype.28 MOLECULAR CONTROL OF PLURIPOTENTI ...
Final presentation
... I would like to respectfully acknowledge the Turrbal and Jagera People, the Traditional Owners of the land on which this event is taking place and Elders both past and present. ...
... I would like to respectfully acknowledge the Turrbal and Jagera People, the Traditional Owners of the land on which this event is taking place and Elders both past and present. ...
Interleukin-6 Gene Expression in Multiple Myeloma: A Characteristic
... population as determined by heavy chain Ig gene rearrangements. The only selection criteria for study were marow aspirate plasmacytosis of greater than 5% and a sufficiently high recovery of purified myeloma cells. Myeloma cell preparation. Heparinized BM aspirates were obtained during routine visit ...
... population as determined by heavy chain Ig gene rearrangements. The only selection criteria for study were marow aspirate plasmacytosis of greater than 5% and a sufficiently high recovery of purified myeloma cells. Myeloma cell preparation. Heparinized BM aspirates were obtained during routine visit ...
programmed cell death in plant
... that may encode a nucleotide-binding domain (82). Other plant genes involved in resistance include typical signal transduction molecules such as the Pto kinase and the Pti kinase of tomato (61, 97). As alluded to above, resistance to pathogens that is conditioned by a genefor-gene interaction is an ...
... that may encode a nucleotide-binding domain (82). Other plant genes involved in resistance include typical signal transduction molecules such as the Pto kinase and the Pti kinase of tomato (61, 97). As alluded to above, resistance to pathogens that is conditioned by a genefor-gene interaction is an ...
When Checkpoints Fail
... (Siede et al., 1994; Paulovich and Hartwell, 1995; Paulovich et al., 1997), or mammalian cells (Painter and Young, 1980; Larner et al., 1994) decrease the rate of ongoing DNA synthesis in response to DNA damage; this inhibition may reflect control at the level of origin initiation and/or at the leve ...
... (Siede et al., 1994; Paulovich and Hartwell, 1995; Paulovich et al., 1997), or mammalian cells (Painter and Young, 1980; Larner et al., 1994) decrease the rate of ongoing DNA synthesis in response to DNA damage; this inhibition may reflect control at the level of origin initiation and/or at the leve ...
Triton X-100 promotes a cholesterol
... We analysed the lipid structure of the cell surface of COS cells by means of two-photon microscopy. The fluorescent probe Laurdan has been used to characterize phase separation in model membranes [24,25] and visualize ordered domains on the surface of living cells [21]. Laurdan does not partition pr ...
... We analysed the lipid structure of the cell surface of COS cells by means of two-photon microscopy. The fluorescent probe Laurdan has been used to characterize phase separation in model membranes [24,25] and visualize ordered domains on the surface of living cells [21]. Laurdan does not partition pr ...
Regulation of cellular homoeostasis by reversible lysine acetylation
... residue may inactivate it). Finally, there may be cross-talk between different types of lysine PTM (ubiquitination, SUMOylation, methylation etc.), all of which occur at the same lysine residue ε-amino group. As such, the addition of another type of lysine PTM may block the ability of a protein to b ...
... residue may inactivate it). Finally, there may be cross-talk between different types of lysine PTM (ubiquitination, SUMOylation, methylation etc.), all of which occur at the same lysine residue ε-amino group. As such, the addition of another type of lysine PTM may block the ability of a protein to b ...
Epithelial differentiation and intercellular junction
... be borne in mind when considering biosynthetic control of junction assembly. Maternally expressed cingulin is detectable as a 140X103 MT protein in unfertilised eggs following either immunoblotting or immunoprecipitation. Synthesis of maternal cingulin is unaffected by fertilisation but runs down af ...
... be borne in mind when considering biosynthetic control of junction assembly. Maternally expressed cingulin is detectable as a 140X103 MT protein in unfertilised eggs following either immunoblotting or immunoprecipitation. Synthesis of maternal cingulin is unaffected by fertilisation but runs down af ...
Lecture 1 Part I Nordström 13.9.
... • Sites of protein synthesis • Composed of polypeptides and ribosomal RNA • 70S ribosome composed of smaller 30S and 50S subunits • Many antibacterial drugs act on bacterial ribosomes without affecting larger eukaryotic ribosomes ...
... • Sites of protein synthesis • Composed of polypeptides and ribosomal RNA • 70S ribosome composed of smaller 30S and 50S subunits • Many antibacterial drugs act on bacterial ribosomes without affecting larger eukaryotic ribosomes ...
PC7 and the related proteases Furin and Pace4 regulate E
... the ICM and the TE is initiated during the late eight-cell stage when individual blastomeres enlarge their cell–cell contact areas in a process termed compaction and begin to assemble junctional complexes in a polarized epithelial layer. Two subsequent rounds of symmetric or asymmetric divisions gen ...
... the ICM and the TE is initiated during the late eight-cell stage when individual blastomeres enlarge their cell–cell contact areas in a process termed compaction and begin to assemble junctional complexes in a polarized epithelial layer. Two subsequent rounds of symmetric or asymmetric divisions gen ...
Compound 48/80 Activates Mast Cell Phospholipase D
... Measurement of GTPase Activity. GTPase activity was determined through minor modifications of previously described procedures (Chahdi et al., 1998b). Cells were incubated for 10 min on ice in buffer A (1 mM ATP, 2 mM MgCl2, 0.1 mM EDTA, 1 mM dithiothreitol, 150 mM NaCl, 1 mM phenylmethylsulfonyl flu ...
... Measurement of GTPase Activity. GTPase activity was determined through minor modifications of previously described procedures (Chahdi et al., 1998b). Cells were incubated for 10 min on ice in buffer A (1 mM ATP, 2 mM MgCl2, 0.1 mM EDTA, 1 mM dithiothreitol, 150 mM NaCl, 1 mM phenylmethylsulfonyl flu ...
Biology: Concepts and Connections, 6e (Campbell)
... 7) Some animals have evolved a body form that allows them to run very fast, while others run more slowly. Whereas a cheetah can run at speeds over 50 mph, an elephant can barely run at 15 mph. The most important physical factor behind this variance is the difference in A) the ratio of muscle to thei ...
... 7) Some animals have evolved a body form that allows them to run very fast, while others run more slowly. Whereas a cheetah can run at speeds over 50 mph, an elephant can barely run at 15 mph. The most important physical factor behind this variance is the difference in A) the ratio of muscle to thei ...
Prm1p, a Pheromone-regulated Multispanning Membrane Protein
... Although this relatively detailed mechanistic model accounts well for fusion by viruses and within the secretory pathway, it leaves unexplained a large and important class of membrane fusion—that of cell fusion. Cell fusion occurs between sperm and egg during fertilization, during development in syn ...
... Although this relatively detailed mechanistic model accounts well for fusion by viruses and within the secretory pathway, it leaves unexplained a large and important class of membrane fusion—that of cell fusion. Cell fusion occurs between sperm and egg during fertilization, during development in syn ...
Energization of Transport Processes in Plants. Roles of the Plasma
... root cells, and the individual cells are equipped with thin protrusions, root hairs, that serve to increase the area of the plant-soil interface. Root hairs may constitute more than 60% of the surface area of the root. Using vibrating microelectrodes, it has been possible to detect large H1 currents ...
... root cells, and the individual cells are equipped with thin protrusions, root hairs, that serve to increase the area of the plant-soil interface. Root hairs may constitute more than 60% of the surface area of the root. Using vibrating microelectrodes, it has been possible to detect large H1 currents ...
Comparative analysis of amphibian somite
... Hensen's node) has been examined in stereo with the scanning electron microscope (SEM). Meier (1979) has found that this region is organized into tandemly aligned, repeating circular domains (about 180/tm in diameter). As these structures ('somitomeres') are added to the embryonic axis during neurul ...
... Hensen's node) has been examined in stereo with the scanning electron microscope (SEM). Meier (1979) has found that this region is organized into tandemly aligned, repeating circular domains (about 180/tm in diameter). As these structures ('somitomeres') are added to the embryonic axis during neurul ...
IL-lra - Blood Journal
... underlying this induction, we found that IL-I3 considerably expression from complementary DNA of a human interleukin- I reaugmented the stability of IL-Ira transcripts, from 1.3 hours ceptor antagonist. Nature 343:341, 1990 to 4.5 hours and 12 hours in monocytes and PMN, respec6. Arend WP, Smith MF ...
... underlying this induction, we found that IL-I3 considerably expression from complementary DNA of a human interleukin- I reaugmented the stability of IL-Ira transcripts, from 1.3 hours ceptor antagonist. Nature 343:341, 1990 to 4.5 hours and 12 hours in monocytes and PMN, respec6. Arend WP, Smith MF ...
Pseudolaric Acid B Induced Cell Cycle Arrest, Au
... MTT test. L929 cells (1.0×104 cells/well) were seeded into 96-well culture plates (Nunc, Roskilde, Denmark). After 24 h incubation, different concentration of PAB was added to the plates. Following incubation, cell growth was measured at different time points by addition of 20 µL 3-(4,5-dimethylthia ...
... MTT test. L929 cells (1.0×104 cells/well) were seeded into 96-well culture plates (Nunc, Roskilde, Denmark). After 24 h incubation, different concentration of PAB was added to the plates. Following incubation, cell growth was measured at different time points by addition of 20 µL 3-(4,5-dimethylthia ...
Cellular differentiation
In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.