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Nuclear envelope dynamics during plant cell division suggest
Nuclear envelope dynamics during plant cell division suggest

... the first evidence of a functional nucleo-cytoskeletal bridging complex in plants and a unique opportunity to study NE membrane protein targeting and mobility [10]. A NLS (nuclear localization signal) was found to be involved in their NE targeting, and a C-terminal coiled-coil domain required for bi ...
PDF
PDF

... individual, multicellular organisms also are characterized by a division of labor among distinct cell and tissue types that each play specialized roles in maintaining the fitness of the whole organism. However, divisions of labor are not the unique privilege of animals. As we discuss below, many mic ...
Lysosomal Sequestration of Polyamine
Lysosomal Sequestration of Polyamine

... trials—despite accumulating ~5 times more analogue than parental cells. We now report that treatment of CHO/664 cells with DENSPM results in the formation of numerous large cytoplasmic vacuoles, which on the basis of electron microscopy and cytochemical staining seem to be lysosomal in origin. A s ...
Neurogenesis in Postnatal Mouse Dorsal Root Ganglia
Neurogenesis in Postnatal Mouse Dorsal Root Ganglia

... DRG neurons while sustaining (and possibly proliferating) neuronal precursors present at the time of plat- ...
- ATS Journals
- ATS Journals

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The role of AMPK and CREB-1 in the regulation of mitochondrial
The role of AMPK and CREB-1 in the regulation of mitochondrial

... promoter as a representative promoter since cytochrome c levels correlate well with respiratory chain complexes. We chose the AMP activated kinase (AMPK) and cyclic AMP-response element binding protein 1 (CREB-1) as promising candidates, which could control the process of mitochondrial proliferation ...
Synergistic interaction between C5a and NOD2 signaling
Synergistic interaction between C5a and NOD2 signaling

... as well as circulating innate immune pathways, such as complement, are activated by pathogens/danger signals, inducing inflammatory responses in response to infection and/or tissue injury. While individual signaling pathways for PRRs and complement are relatively well understood, the complex interac ...
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Chromium(VI) treatment of normal human lung cells results in

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The Nucleolus under Stress
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D:\ACTA\3-2003\jozwiak 732.vp
D:\ACTA\3-2003\jozwiak 732.vp

... GSH-related enzymes in cultured normal and diabetic human fibroblasts. Cells were incubated with 4 mM daunorubicin (DNR) for 2 h followed by culture in drug-free medium for up to 72 h. Treatment of diabetic cells with the drug caused a time-dependent depletion of intracellular GSH and a decrease of ...
the cell cycle in action - Oxford Academic
the cell cycle in action - Oxford Academic

... process that is under the control of strict and often overlapping regulatory systems that aim to ensure the successful production of progeny cells. It is regulated through a number of different supervisory mechanisms, with phosphorylation and ubiquitin-dependent degradation of key regulatory protein ...
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Regulation of the Discs Large Tumor Suppressor by a

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Full Text  - Plant and Cell Physiology
Full Text - Plant and Cell Physiology

... All rights reserved. For permissions, please email: journals.permissions@oup.com ...
Cell Biology - Educational Services
Cell Biology - Educational Services

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Noonan
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... CTCF: marks insulators and promoters RAD21 (cohesin): marks insulators, promoters and enhancers ...
Ex vivo processing for maturation of Arabidopsis
Ex vivo processing for maturation of Arabidopsis

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Pdf - Text of NPTEL IIT Video Lectures

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... These observations point to a major role for integrins in S2R+ cell spreading and indicate that S2 cells spread on concanavalin A by an integrin-independent mechanism. We next tested if this difference in spreading can be exploited to screen for novel regulators of integrin-mediated cell spreading. ...
Bacteria Section 18.2 Summary – pages 484-495
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Effect of topical rebamipide on goblet cells in the lid wiper of human

... lial cells showed membranous immunoreactivity for EGFR; grade 1, membranous immunoreactivity was present in >10, <50% of the epithelial cells; grade 2, if membranous immu‑ noreactivity was present in >50, <90% of the epithelial cells; and grade 3, if >90% of the epithelial cells had strong staining ...
Brief rapid pacing depresses contractile function via Ca
Brief rapid pacing depresses contractile function via Ca

... RP-induced inhibition of cell shortening. Measurements of peak cell shortening were determined as an average of the last five beats at each pacing cycle length using a custom software program (LabView). The RP protocol was always accomplished by stimulated action potentials. Because RP induces susta ...
Brief rapid pacing depresses contractile function via Ca - AJP
Brief rapid pacing depresses contractile function via Ca - AJP

... RP-induced inhibition of cell shortening. Measurements of peak cell shortening were determined as an average of the last five beats at each pacing cycle length using a custom software program (LabView). The RP protocol was always accomplished by stimulated action potentials. Because RP induces susta ...
From induction to conduction: how intrinsic transcriptional priming of
From induction to conduction: how intrinsic transcriptional priming of

... a particular neuronal subtype [7,8]. These powerful transcription factors are both necessary and sufficient to induce key features of a subtype-specific identity, including the molecular expression patterns, morphology, electrophysiology and neurotransmitter status of a developing neuron. It would b ...
(2002) Thyroxine induces pancreatic beta cell apoptosis in rats
(2002) Thyroxine induces pancreatic beta cell apoptosis in rats

... pancreas due to thyroid hormone-induced apoptosis in the hyperthyroid state puts an increased demand on each single remaining beta cell, which have to compensate for the increased insulin requirements due to thyroxine-induced peripheral insulin resistance [2]. An increase of the blood glucose concen ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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