Patterns of Collective Bacterial Motion in Microfluidic Devices
... trient availability or faster biochemical signal propagation due to enhanced diffusion). Interestingly, pattern formation has also been observed for suspensions of non-active agents.8 Settling of colloid particles under gravitation is an actively studied field of statistical mechanics, and computat ...
... trient availability or faster biochemical signal propagation due to enhanced diffusion). Interestingly, pattern formation has also been observed for suspensions of non-active agents.8 Settling of colloid particles under gravitation is an actively studied field of statistical mechanics, and computat ...
Article - Columbia University
... Cell Counts We chose to examine n. IX-X number at three developmental time points in addition to adulthood. Stage 54 marks the beginning of thyroxine secretion, an event that is required in Xenopus for (a) initiation of metamorphosis, (b) initiation of motor neuron death in the spinal cord, and (c) ...
... Cell Counts We chose to examine n. IX-X number at three developmental time points in addition to adulthood. Stage 54 marks the beginning of thyroxine secretion, an event that is required in Xenopus for (a) initiation of metamorphosis, (b) initiation of motor neuron death in the spinal cord, and (c) ...
Ubiquitination and sumoylation of the HTLV-2 κB activity: a
... encompassing the four C-terminal amino acids responsible for the binding to several PDZ domain-containing proteins [16-18]. In addition, some HTLV-2 subtypes express shorter versions of Tax-2 (namely Tax-2A and Tax-2CG) which, contrary to Tax-2B, do not functionally inactivate p53 [10,19]. Recent st ...
... encompassing the four C-terminal amino acids responsible for the binding to several PDZ domain-containing proteins [16-18]. In addition, some HTLV-2 subtypes express shorter versions of Tax-2 (namely Tax-2A and Tax-2CG) which, contrary to Tax-2B, do not functionally inactivate p53 [10,19]. Recent st ...
Centromere dynamics
... the depleted cells, remains to be seen. If budding yeast CenH3 can recognize CENP-A and/or mammalian CEN DNA and incorporate into a human centromere, then what is the specificity determinant? There is no indication that histones or their variants exhibit strict DNA sequence specificity. There are se ...
... the depleted cells, remains to be seen. If budding yeast CenH3 can recognize CENP-A and/or mammalian CEN DNA and incorporate into a human centromere, then what is the specificity determinant? There is no indication that histones or their variants exhibit strict DNA sequence specificity. There are se ...
Programmed Cell Death in Neurons
... to be conserved in organisms as diverse as mammals, Drosophila melanogaster, and Caenorhabditis elegans. Much of the current research in mammalian cells focuses on the homologs of the cell death genes identified through genetic analysis in C. elegans (see below). Although mutations in single cell de ...
... to be conserved in organisms as diverse as mammals, Drosophila melanogaster, and Caenorhabditis elegans. Much of the current research in mammalian cells focuses on the homologs of the cell death genes identified through genetic analysis in C. elegans (see below). Although mutations in single cell de ...
- KoreaMed Synapse
... for 7 days. On day 8, CD4 and CD8 T cell populations among CD24 mature thymocytes and total splenocytes (A) and the expression levels of CD44 and CXCR3 on CD8 T cells from the thymus and spleen (B) were compared with those of WT and CIITATg mice. Representative flow cytometry data (left panel) and s ...
... for 7 days. On day 8, CD4 and CD8 T cell populations among CD24 mature thymocytes and total splenocytes (A) and the expression levels of CD44 and CXCR3 on CD8 T cells from the thymus and spleen (B) were compared with those of WT and CIITATg mice. Representative flow cytometry data (left panel) and s ...
Influence of Notch on dorsoventral
... observations imply that Hh signaling influences compartmentalization by promoting an anterior-type cell affinity. Ap influences DV compartmentalization through at least two distinct mechanisms, which appear to act sequentially. First, Ap promotes the dorsal expression of Tartan (Trn) and Capricious ...
... observations imply that Hh signaling influences compartmentalization by promoting an anterior-type cell affinity. Ap influences DV compartmentalization through at least two distinct mechanisms, which appear to act sequentially. First, Ap promotes the dorsal expression of Tartan (Trn) and Capricious ...
The zebrafish midblastula transition - Development
... indicating possible MBT-like cell cycle lengthening. In studies on the loach, Misgurnus fossilis, Rott and Shevelava (1967) found a more defined cell cycle lengthening, which did not occur until cycle 11, and, in the same study, they found the equivalent cell cycle lengthening in haploid embryos occ ...
... indicating possible MBT-like cell cycle lengthening. In studies on the loach, Misgurnus fossilis, Rott and Shevelava (1967) found a more defined cell cycle lengthening, which did not occur until cycle 11, and, in the same study, they found the equivalent cell cycle lengthening in haploid embryos occ ...
Epigenetic and transcriptional regulation of early mouse development
... Formation of the endoderm .......................................................................................................................9 In vitro model of germ layer formation .............................................................................................. 10 The Wnt pathway ...
... Formation of the endoderm .......................................................................................................................9 In vitro model of germ layer formation .............................................................................................. 10 The Wnt pathway ...
Protected Cell Companies Act 1999
... registered with the Registrar from time to time, and in the case of a protected cell company which is registered by way of continuation of a foreign company, means the Articles of Association as registered with the Registrar by way of continuation; “Authority” means the Mauritius Offshore Business A ...
... registered with the Registrar from time to time, and in the case of a protected cell company which is registered by way of continuation of a foreign company, means the Articles of Association as registered with the Registrar by way of continuation; “Authority” means the Mauritius Offshore Business A ...
how the ubiquitin–proteasome system controls transcription
... establishes the mechanism through which uH2B contributes to gene silencing, and indicates that histone ubiquitylation is an integral part of the HISTONE CODE25 that cells use to distinguish transcriptionally active from inactive chromatin. But how does ubiquitylation regulate other histone modificat ...
... establishes the mechanism through which uH2B contributes to gene silencing, and indicates that histone ubiquitylation is an integral part of the HISTONE CODE25 that cells use to distinguish transcriptionally active from inactive chromatin. But how does ubiquitylation regulate other histone modificat ...
Text
... serous B cells and germinal center formation13,15. The existence of similar lymphoid structures has been reported in the adipose deposits of the pleural cavity, the mediastinum13,16–18 and the pericardium13. Although the density of FALCs in pericardium and mediastinum is high13, the functional role ...
... serous B cells and germinal center formation13,15. The existence of similar lymphoid structures has been reported in the adipose deposits of the pleural cavity, the mediastinum13,16–18 and the pericardium13. Although the density of FALCs in pericardium and mediastinum is high13, the functional role ...
Experimental conditions affect the site of tetrazolium
... coloured formazan is irreversible and can be quantified using spectrophotometry. Two types of tetrazolium salts are used in the context of microbiological studies, either in nutritive media where cells are growing or in non-nutritive media where cells do not grow and are thus in a resting state. The ...
... coloured formazan is irreversible and can be quantified using spectrophotometry. Two types of tetrazolium salts are used in the context of microbiological studies, either in nutritive media where cells are growing or in non-nutritive media where cells do not grow and are thus in a resting state. The ...
Nup358 interacts with APC and plays a role in cell polarization
... line that expresses a truncated APC protein that retains amino acids 1-1555 (containing part of APC-M but lacking all axin-binding domains). Truncated APC from HT29 could be coimmunoprecipitated with Nup358 (Fig. 4A), suggesting that the interaction between APC and Nup358 does not require axin. To i ...
... line that expresses a truncated APC protein that retains amino acids 1-1555 (containing part of APC-M but lacking all axin-binding domains). Truncated APC from HT29 could be coimmunoprecipitated with Nup358 (Fig. 4A), suggesting that the interaction between APC and Nup358 does not require axin. To i ...
Gene Section PTPRJ (protein tyrosine phosphatase, receptor type, J)
... Whether or not DEP-1 plays a role in hematologic malignancies is not clear. DEP1 targets VEGFR2 phospho-tyrosines: In contactinhibited endothelial cells, the phosphatase DEP-1, by binding beta-catenin and p120, may associate with the cadherin-receptor complex and dephosphorylate VEGFR-2 that is in c ...
... Whether or not DEP-1 plays a role in hematologic malignancies is not clear. DEP1 targets VEGFR2 phospho-tyrosines: In contactinhibited endothelial cells, the phosphatase DEP-1, by binding beta-catenin and p120, may associate with the cadherin-receptor complex and dephosphorylate VEGFR-2 that is in c ...
Insulin and insulin-like growth factor I (IGF I) in early
... insulin, which can bind to the specific receptors and IGF receptors type I (Hill and Milner, 1985), or by the locally secreted IGF I (autocrine and paracrine growth control) (D'Ercole et al. 1980). Indirect regulation is mediated by insulin (Brinsmead and Liggins, 1979; Philips and Vassilopoulou-Sel ...
... insulin, which can bind to the specific receptors and IGF receptors type I (Hill and Milner, 1985), or by the locally secreted IGF I (autocrine and paracrine growth control) (D'Ercole et al. 1980). Indirect regulation is mediated by insulin (Brinsmead and Liggins, 1979; Philips and Vassilopoulou-Sel ...
Oct-4 controls cell-cycle progression of embryonic stem cells
... Inhibition of proliferation is typically associated with cellcycle arrest. To investigate this possibility, ZHBTc4 ES cells were cultured in the absence (−Dox) or presence ( + Dox) of doxycycline for 72 h. The DNA contents were then analysed by PI staining and flow cytometry. The down-regulation of ...
... Inhibition of proliferation is typically associated with cellcycle arrest. To investigate this possibility, ZHBTc4 ES cells were cultured in the absence (−Dox) or presence ( + Dox) of doxycycline for 72 h. The DNA contents were then analysed by PI staining and flow cytometry. The down-regulation of ...
Melanotransferrin stimulates t-PA
... and sMTf compared to incubation without sMTf (Fig. 2A). This reduction of Fn suggests that sMTf treatment induces the degradation of Fn by generated plasmin. Interestingly, higher concentrations of plasminogen led to a 45% reduction in Fn detection, while the same experiment performed with 500 nM of ...
... and sMTf compared to incubation without sMTf (Fig. 2A). This reduction of Fn suggests that sMTf treatment induces the degradation of Fn by generated plasmin. Interestingly, higher concentrations of plasminogen led to a 45% reduction in Fn detection, while the same experiment performed with 500 nM of ...
Oxidative Stress Contributes to Autophagy
... 2012a). Reactive oxygen species (ROS) are potent inducers of autophagy in C. reinhardtii and plants (Liu and Bassham, 2012; Pérez-Pérez et al., 2012b). Indeed, a link between photo-oxidative damage, ROS accumulation, and autophagy activation has been shown in C. reinhardtii cells with a decreased ca ...
... 2012a). Reactive oxygen species (ROS) are potent inducers of autophagy in C. reinhardtii and plants (Liu and Bassham, 2012; Pérez-Pérez et al., 2012b). Indeed, a link between photo-oxidative damage, ROS accumulation, and autophagy activation has been shown in C. reinhardtii cells with a decreased ca ...
Spotting the enemy within: Targeted silencing of foreign DNA in
... its genomic targets, with some 12 C-terminal ZNFs being dispensable for DNA-recognition [8]. Furthermore, CTCF, a KRAB-less tandem-ZFP with 11 ZNFs was shown to bind to various motifs via clustering its ZNFs in several combinations [24]. Several DNA binding prediction models for tandemZFPs have been ...
... its genomic targets, with some 12 C-terminal ZNFs being dispensable for DNA-recognition [8]. Furthermore, CTCF, a KRAB-less tandem-ZFP with 11 ZNFs was shown to bind to various motifs via clustering its ZNFs in several combinations [24]. Several DNA binding prediction models for tandemZFPs have been ...
Like-acetylglucosaminyltransferase (LARGE)
... blotting using (i) the monoclonal antibody IIH6, which recognizes the glycosylated form of α-dystroglycan and inhibits its ligand-binding activity, and (ii) an anti-Fc antibody, which binds the Fc moiety on the α-dystroglycan mutants independent of posttranslational modifications and thus provides an ...
... blotting using (i) the monoclonal antibody IIH6, which recognizes the glycosylated form of α-dystroglycan and inhibits its ligand-binding activity, and (ii) an anti-Fc antibody, which binds the Fc moiety on the α-dystroglycan mutants independent of posttranslational modifications and thus provides an ...
Gram Stain - American Proficiency Institute
... Common modifications of the classic Gram stain procedure involve variations in fixation method, reagents, and timing. Fixation, which attaches the specimen to the slide before staining, can be done with heat or methanol. In heat fixation, the slide is gently warmed so that all moisture evaporates fr ...
... Common modifications of the classic Gram stain procedure involve variations in fixation method, reagents, and timing. Fixation, which attaches the specimen to the slide before staining, can be done with heat or methanol. In heat fixation, the slide is gently warmed so that all moisture evaporates fr ...
Title Non-coding functions of alternative pre-mRNA - DR-NTU
... Intron 1 in the 5’UTR of mRNA encoding chick proinsulin, an insulin precursor essential for proper development and metabolism, is increasingly retained during embryogenesis, thus reducing mRNA translational activity and lowering proinsulin production [36]. This intron-retaining isoform is up-regulat ...
... Intron 1 in the 5’UTR of mRNA encoding chick proinsulin, an insulin precursor essential for proper development and metabolism, is increasingly retained during embryogenesis, thus reducing mRNA translational activity and lowering proinsulin production [36]. This intron-retaining isoform is up-regulat ...
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1
... mRNA levels in DFO-treated cells was statistically significant, another experiment was performed in which cells were treated for 20 hours with either 100 M DFO or sterile water as a control. The mean FPN1 mRNA level in DFO-treated cells was 23%⫾ 5% (⫾ SE, n ⫽ 4) lower than control (P ⫽ .012). For c ...
... mRNA levels in DFO-treated cells was statistically significant, another experiment was performed in which cells were treated for 20 hours with either 100 M DFO or sterile water as a control. The mean FPN1 mRNA level in DFO-treated cells was 23%⫾ 5% (⫾ SE, n ⫽ 4) lower than control (P ⫽ .012). For c ...
Cellular differentiation
In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.