Comparison of Methods for Estimating Unbound Intracellular
... Animal Bridging Research Organization. Three lots of liver samples were pooled and homogenized in 66.7 mM isotonic phosphate buffer at 1:3 (w/v) producing 25% homogenates. By diluting these homogenates, 12.5% and 6.25% homogenates were also prepared. Diazepam, pitavastatin, pravastatin, and rosuvast ...
... Animal Bridging Research Organization. Three lots of liver samples were pooled and homogenized in 66.7 mM isotonic phosphate buffer at 1:3 (w/v) producing 25% homogenates. By diluting these homogenates, 12.5% and 6.25% homogenates were also prepared. Diazepam, pitavastatin, pravastatin, and rosuvast ...
GENETIC CONTROL OF TISSUE SPECIFIC GROWTH IN THE
... trachea. Prior to this study, two genes, uninflatable (uif) and Matrix metalloproteinase I (Mmp1), were identified that have defects in larval tracheal-specific growth (Zhang and Ward, 2009, Glasheen et al. 2010). uif was characterized for its role in tracheal development and growth in Drosophila. u ...
... trachea. Prior to this study, two genes, uninflatable (uif) and Matrix metalloproteinase I (Mmp1), were identified that have defects in larval tracheal-specific growth (Zhang and Ward, 2009, Glasheen et al. 2010). uif was characterized for its role in tracheal development and growth in Drosophila. u ...
REACTIVATION IN VITRO OF IMMUNOCOMPETENCE IN
... an Fx thymus, incapable of evoking splenomegaly in a syngeneic FI neonatal spleen, caused reactivity in combination with the irradiated parental spleen, excluding the possibility of direct participation of thymus cells in the reaction; and (c) furthermore, preliminary studies2 have shown thymus acti ...
... an Fx thymus, incapable of evoking splenomegaly in a syngeneic FI neonatal spleen, caused reactivity in combination with the irradiated parental spleen, excluding the possibility of direct participation of thymus cells in the reaction; and (c) furthermore, preliminary studies2 have shown thymus acti ...
Proper Folding and Endoplasmic Reticulum to Golgi
... charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact. § To whom correspondence should be addressed: Dept. of Dermatology, Yale University School of Medicine, P. O. Box 208059, 15 York St., ...
... charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact. § To whom correspondence should be addressed: Dept. of Dermatology, Yale University School of Medicine, P. O. Box 208059, 15 York St., ...
Targeted wild-type and jerker espins reveal a novel, WH2
... fashion throughout a given section (Fig. 2B-D). Fig. 1. Formation of a centrosomal actin bundle (CAB) in neuronal cells transfected with GFP-espin (green). (A-C) Colocalization of GFP-espin (B) and F-actin labeled with Texas-Red-phalloidin (C, red) in a large perinuclear actin bundle in a transfecte ...
... fashion throughout a given section (Fig. 2B-D). Fig. 1. Formation of a centrosomal actin bundle (CAB) in neuronal cells transfected with GFP-espin (green). (A-C) Colocalization of GFP-espin (B) and F-actin labeled with Texas-Red-phalloidin (C, red) in a large perinuclear actin bundle in a transfecte ...
The OBO Foundry Project
... A molecular function is a propensity of a gene product instance to perform actions on the molecular level of granularity. Hypothesis 1: these actions must be reliably such as to contribute to biological processes. Hypothesis 2: these actions must be reliably such as to contribute to the organism’s r ...
... A molecular function is a propensity of a gene product instance to perform actions on the molecular level of granularity. Hypothesis 1: these actions must be reliably such as to contribute to biological processes. Hypothesis 2: these actions must be reliably such as to contribute to the organism’s r ...
SECHENOV MEDICAL ACADEMY, MOSCOW Department of
... (3) Cellular junctions. There are some types of cellular junctions. A. The tight or occluding type. This type of junction is created by localized sealing of the outer leaflets of adjacent plasma membranes. These junctions prevent the passage of water between the adjacent cells. These junctions are l ...
... (3) Cellular junctions. There are some types of cellular junctions. A. The tight or occluding type. This type of junction is created by localized sealing of the outer leaflets of adjacent plasma membranes. These junctions prevent the passage of water between the adjacent cells. These junctions are l ...
The glycocalyx is present as soon as blood flow is initiated and is
... the glycocalyx layer is present as soon as blood flow starts (14 somites). Selective degradations of major glycocalyx components were shown to inhibit normal vascular development, examined through morphology, vascular barrier function, and gene expression. & 2012 Elsevier Inc. All rights reserved. ...
... the glycocalyx layer is present as soon as blood flow starts (14 somites). Selective degradations of major glycocalyx components were shown to inhibit normal vascular development, examined through morphology, vascular barrier function, and gene expression. & 2012 Elsevier Inc. All rights reserved. ...
ABSTRACT Title of Dissertation: GENETIC REGULATION OF AUTOPHAGIC CELL... Sudeshna Dutta, Doctor of Philosophy, 2008
... between cell growth, division and death can cause a variety of disorders including cancer and neurodegenerative diseases (Thompson, 1995). While the relationship between the cell cycle and cell death has been intensely studied, the relationship between cell growth and cell death is not that well cha ...
... between cell growth, division and death can cause a variety of disorders including cancer and neurodegenerative diseases (Thompson, 1995). While the relationship between the cell cycle and cell death has been intensely studied, the relationship between cell growth and cell death is not that well cha ...
Organelle Assembly in Yeast: Characterization of
... enzymatically active Inv to the yeast vacuole (2, 21). Mutants have been selected that missort and secrete such CPY-Inv hybrid proteins. The 'x,600 mutants isolated thus far have been assigned to more than 33 complementation groups. The mutants exhibit hybrid protein-independent defects in the sorti ...
... enzymatically active Inv to the yeast vacuole (2, 21). Mutants have been selected that missort and secrete such CPY-Inv hybrid proteins. The 'x,600 mutants isolated thus far have been assigned to more than 33 complementation groups. The mutants exhibit hybrid protein-independent defects in the sorti ...
7 - Dynamic Microtubules and the Texture of Plant Cell Walls
... past 50 years or so. Virtually, all the seminal ideas about wall construction originated in the electron microscopic era when the field divided between those who believed that layers of cellulose microfibrils were organized entirely by self-assembly principles (and may or may not be subsequently rea ...
... past 50 years or so. Virtually, all the seminal ideas about wall construction originated in the electron microscopic era when the field divided between those who believed that layers of cellulose microfibrils were organized entirely by self-assembly principles (and may or may not be subsequently rea ...
Temporal and Spatial Distribution of DNA Topoisomerase II Alters
... with striking similarities in their amino acid sequences, are encoded by different genes. The topo IIa staining showed fine punctuate fluorescence all over the nucleus except the nucleolar domain.13,14 Although topo IIb was considered to exist preferentially in the nucleoli,14,15 a recent report has ...
... with striking similarities in their amino acid sequences, are encoded by different genes. The topo IIa staining showed fine punctuate fluorescence all over the nucleus except the nucleolar domain.13,14 Although topo IIb was considered to exist preferentially in the nucleoli,14,15 a recent report has ...
INTRODUCTION - Austin Community College
... o students are familiar with the parts of a typical animal cell o students are familiar with the function of cellular parts, including plasma membrane, cytosol, and organelles o students are familiar with cellular processes, including homeostasis, permeability, energy production, transportation of m ...
... o students are familiar with the parts of a typical animal cell o students are familiar with the function of cellular parts, including plasma membrane, cytosol, and organelles o students are familiar with cellular processes, including homeostasis, permeability, energy production, transportation of m ...
Daughter-Specific Transcription Factors Regulate Cell Size Control
... In budding yeast, asymmetric cell division yields a larger mother and a smaller daughter cell, which transcribe different genes due to the daughter-specific transcription factors Ace2 and Ash1. Cell size control at the Start checkpoint has long been considered to be a main regulator of the length of ...
... In budding yeast, asymmetric cell division yields a larger mother and a smaller daughter cell, which transcribe different genes due to the daughter-specific transcription factors Ace2 and Ash1. Cell size control at the Start checkpoint has long been considered to be a main regulator of the length of ...
Eucalyptus grandis cellulose synthase 1 Arabidopsis thaliana MARJA M. O’NEILL
... Arabidopsis thaliana has proven to be especially useful in studying the function of CESA proteins by analysing plant development and cell wall chemistry in plants with mutated CesA genes. Although Arabidopsis does not form large quantities of secondary xylem, it has been shown to undergo secondary g ...
... Arabidopsis thaliana has proven to be especially useful in studying the function of CESA proteins by analysing plant development and cell wall chemistry in plants with mutated CesA genes. Although Arabidopsis does not form large quantities of secondary xylem, it has been shown to undergo secondary g ...
the signaling role of the accessory receptors cd2 and cd6 in t cell
... include activation of protein kinases and phosphorylation of many substrates, including the TCR, and the formation of protein complexes containing adaptors and enzymes. These “proximal” events culminate in cellular responses such as proliferation, differentiation and secretion of cytokines and growt ...
... include activation of protein kinases and phosphorylation of many substrates, including the TCR, and the formation of protein complexes containing adaptors and enzymes. These “proximal” events culminate in cellular responses such as proliferation, differentiation and secretion of cytokines and growt ...
Leveau2008 - Johan Leveau
... wide range of taxonomically distinct bacteria, including actinomycetes, β-proteobacteria, bacilli and myxobacteria (de Boer et al., 2005). Much of the published literature on fungicidal factors produced by bacteria has been generated in the context of mushroom pathogenesis, biocontrol of fungal path ...
... wide range of taxonomically distinct bacteria, including actinomycetes, β-proteobacteria, bacilli and myxobacteria (de Boer et al., 2005). Much of the published literature on fungicidal factors produced by bacteria has been generated in the context of mushroom pathogenesis, biocontrol of fungal path ...
the 5 kingdmcard 5 - Henrico County Public Schools
... Photosynthesis is the process in which plants make food from water and carbon dioxide while in the presence of sunlight. SOL 5.5 ...
... Photosynthesis is the process in which plants make food from water and carbon dioxide while in the presence of sunlight. SOL 5.5 ...
The Aspergillus fumigatus cspA Gene Encoding a Repeat
... pathogen and the major causative agent of invasive aspergillosis, a life-threatening disease primarily affecting immunocompromised patients (12, 16, 38). Molecular analyses have revealed numerous virulence attributes that enable A. fumigatus to infect the human host, including the production of toxi ...
... pathogen and the major causative agent of invasive aspergillosis, a life-threatening disease primarily affecting immunocompromised patients (12, 16, 38). Molecular analyses have revealed numerous virulence attributes that enable A. fumigatus to infect the human host, including the production of toxi ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).