Datasheet Blank Template - Santa Cruz Biotechnology
... κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors ...
... κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors ...
The Wnt signaling pathway mechanisms
... which modifies histone deacetylases (Hdac) and as such influences gene expression (Karamboulas et al., 2006; Kuhl and Pandur, 2008) (figure 1D). ...
... which modifies histone deacetylases (Hdac) and as such influences gene expression (Karamboulas et al., 2006; Kuhl and Pandur, 2008) (figure 1D). ...
Amino acid regulation of mTORC1 Liron Bar-Peled
... when deregulated, it is implicated in the pathogenesis of common cancers. mTORC1 responds to a diverse set of stimuli, including growth factors, oxygen availability, energy and amino acid levels in order to control essential anabolic and catabolic processes. Amino acids promote mTORC1 shuttling to t ...
... when deregulated, it is implicated in the pathogenesis of common cancers. mTORC1 responds to a diverse set of stimuli, including growth factors, oxygen availability, energy and amino acid levels in order to control essential anabolic and catabolic processes. Amino acids promote mTORC1 shuttling to t ...
VINNITSA NATIONAL MEDICAL UNIVERSITY BY N.I.PIROGOV
... numerous terminal branches that form neuro-muscular synapses with the muscle cell. The somatic efferent motor neurons are especially numerous in the cervical and lumbar segments (lateral nucleus). Motor neurons are associated with the upper and lower limb musculature respectively. Their axons contri ...
... numerous terminal branches that form neuro-muscular synapses with the muscle cell. The somatic efferent motor neurons are especially numerous in the cervical and lumbar segments (lateral nucleus). Motor neurons are associated with the upper and lower limb musculature respectively. Their axons contri ...
Collagen in the Human Lung
... 50 ,.tM; Schwarz/Mann, 260 mCi/mmol) was added. Incubation of the aliquots was continued for 1, 2, or 3 h (fetal) or 1, 2, 3, or 4 h (adult). The subsequent handling of each incubation was identical to that described for rabbit lung incubations (4). At each hour of incubation, measurements were made ...
... 50 ,.tM; Schwarz/Mann, 260 mCi/mmol) was added. Incubation of the aliquots was continued for 1, 2, or 3 h (fetal) or 1, 2, 3, or 4 h (adult). The subsequent handling of each incubation was identical to that described for rabbit lung incubations (4). At each hour of incubation, measurements were made ...
Intraflagellar transport and the generation of dynamic, structurally
... (kinesin-II and OSM-3/KIF17) can differentially mobilize the intraflagellar transport machinery required for ciliogenesis and, presumably, different cargo to help generate dynamic, structurally and functionally distinct cilia. Evolution, prevalence and functions of eukaryotic cilia A remarkable feat ...
... (kinesin-II and OSM-3/KIF17) can differentially mobilize the intraflagellar transport machinery required for ciliogenesis and, presumably, different cargo to help generate dynamic, structurally and functionally distinct cilia. Evolution, prevalence and functions of eukaryotic cilia A remarkable feat ...
as a PDF - CiteSeerX
... CD34 antibodies, confirming the association between CrkL and CD34. CD34 peptide inhibition assays demonstrated that CrkL interacts at a membrane-proximal region of the CD34 tail. To identify the CrkL domain responsible for interaction with CD34, we generated GST-fusion constructs of adapter proteins ...
... CD34 antibodies, confirming the association between CrkL and CD34. CD34 peptide inhibition assays demonstrated that CrkL interacts at a membrane-proximal region of the CD34 tail. To identify the CrkL domain responsible for interaction with CD34, we generated GST-fusion constructs of adapter proteins ...
Sharing In The Swap Shop - Memes, Groups and Altruism
... increase the time required for a single group to dominate the population due to the increase in intergroup conflict. This may not however, be the case when the number of tags are increased (see Axelrod 1995). 5.4 "Genetic" v. Cultural Evolution The “genetic” experiments B, D produced similar results ...
... increase the time required for a single group to dominate the population due to the increase in intergroup conflict. This may not however, be the case when the number of tags are increased (see Axelrod 1995). 5.4 "Genetic" v. Cultural Evolution The “genetic” experiments B, D produced similar results ...
FOCAL ADHESION KINASE: IN COMMAND AND CONTROL OF
... as focal contacts (BOX 1). Focal contacts are formed at ECM–integrin junctions that bring together cytoskeletal and signalling proteins during the processes of cell adhesion, spreading and migration. Early studies found that FAK could be activated by either ECM or growth factors, and that tyrosine p ...
... as focal contacts (BOX 1). Focal contacts are formed at ECM–integrin junctions that bring together cytoskeletal and signalling proteins during the processes of cell adhesion, spreading and migration. Early studies found that FAK could be activated by either ECM or growth factors, and that tyrosine p ...
Cleavage modification did not alter early blastomere fates
... than its partners 1ai12, 1bi12 and 1ci12 (Figure S1), while the cell 1de11 divides 2h later than its quar- ...
... than its partners 1ai12, 1bi12 and 1ci12 (Figure S1), while the cell 1de11 divides 2h later than its quar- ...
The EMBO Journal (2002) 21, 1704–1712
... N-terminus. Chromodomains are found in many chromatin-related proteins, and have been proposed to mediate protein–RNA interaction (Akhtar and Becker, 2001) or binding to methylated lysines (Bannister et al., 2001; Lachner et al., 2001). Many studies have shown that Tip60 can regulate transcription, ...
... N-terminus. Chromodomains are found in many chromatin-related proteins, and have been proposed to mediate protein–RNA interaction (Akhtar and Becker, 2001) or binding to methylated lysines (Bannister et al., 2001; Lachner et al., 2001). Many studies have shown that Tip60 can regulate transcription, ...
The Ovule and the Embryo Sac
... ovule illustrated in Figure 1 is representative of the most frequently observed form (Bouman, 1984). Ovules are specialized structures, derived from the placenta of the ovary wall, that produce the megasporocyte and are the site of embryo sac formation, fertilization, and embryogenesis (see also Gas ...
... ovule illustrated in Figure 1 is representative of the most frequently observed form (Bouman, 1984). Ovules are specialized structures, derived from the placenta of the ovary wall, that produce the megasporocyte and are the site of embryo sac formation, fertilization, and embryogenesis (see also Gas ...
Article Title Authors Author affiliation Correspondence information
... ERK1/2, p38MAPK (p38 Į/ȕ/Ȗ/į), ERK7/8, ERK3/4, and ERK5/BMK1 (big MAP kinase 1) [17]. After activation by upstream kinases, different subfamilies regulate ...
... ERK1/2, p38MAPK (p38 Į/ȕ/Ȗ/į), ERK7/8, ERK3/4, and ERK5/BMK1 (big MAP kinase 1) [17]. After activation by upstream kinases, different subfamilies regulate ...
Loss of Klf4 in Mice Causes Altered Proliferation and Differentiation
... cancer.12 Targeted gene disruption of TFF2/SP leads to decreased cell proliferation and increased susceptibility to nonsteroidal anti-inflammatory drug injury.13 TFF2, which normally is expressed in mucus neck cells,3 is also an important marker for the development of gastric cancer.14 Aberrant expr ...
... cancer.12 Targeted gene disruption of TFF2/SP leads to decreased cell proliferation and increased susceptibility to nonsteroidal anti-inflammatory drug injury.13 TFF2, which normally is expressed in mucus neck cells,3 is also an important marker for the development of gastric cancer.14 Aberrant expr ...
Differential Auxin-Transporting Activities of PIN
... similar molecular structures, the long-looped PINs exhibit sequence divergence not only in their central loop, but also in certain residues of the transmembrane domains. This structural divergence of long-looped PINs might be indicative of their differential auxintransporting activities, which have ...
... similar molecular structures, the long-looped PINs exhibit sequence divergence not only in their central loop, but also in certain residues of the transmembrane domains. This structural divergence of long-looped PINs might be indicative of their differential auxintransporting activities, which have ...
The Drosophila ribbon gene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis. Development 128, 4923-4933. pdf
... membrane protrusions but little net movement or branch formation. rib mutant tracheal cells are still responsive to the Branchless fibroblast growth factor (FGF) that guides branch outgrowth, and they express apical membrane markers normally. This suggests that the defect lies either ...
... membrane protrusions but little net movement or branch formation. rib mutant tracheal cells are still responsive to the Branchless fibroblast growth factor (FGF) that guides branch outgrowth, and they express apical membrane markers normally. This suggests that the defect lies either ...
PDF
... occurrence in the pole plasm, the two proteins displayed distinct distribution patterns. In particular, no GFP-SmB could be detected in the nuage or at the anterior cortex of the oocyte (Fig. 1C and 1D insets). In the oocyte nucleus of previtellogenic egg chambers, GFP-SmB was detected in a spherica ...
... occurrence in the pole plasm, the two proteins displayed distinct distribution patterns. In particular, no GFP-SmB could be detected in the nuage or at the anterior cortex of the oocyte (Fig. 1C and 1D insets). In the oocyte nucleus of previtellogenic egg chambers, GFP-SmB was detected in a spherica ...
A three-stage model of Golgi structure and function
... studies of mammalian glycosylation enzymes have not yielded such clear-cut distinctions. As judged by quantitative immunolabeling, individual glycosylation enzymes are most concentrated in particular cisternae, but they have overlapping distributions across the stack (Nilsson et al. 1993; Rabouille ...
... studies of mammalian glycosylation enzymes have not yielded such clear-cut distinctions. As judged by quantitative immunolabeling, individual glycosylation enzymes are most concentrated in particular cisternae, but they have overlapping distributions across the stack (Nilsson et al. 1993; Rabouille ...
Charakterisierung peroxisomaler und Lipid
... It was shown that Lpx1p is present in the peroxisome but Ldh1p is predominantly localized to lipid droplets. Lpx1p as well as Ldh1p comprises the typical GXSXG-type lipase motif of members of the α/β-hydrolase family. Both proteins carry a putative peroxisomal targeting signal type-1 (PTS1) and can ...
... It was shown that Lpx1p is present in the peroxisome but Ldh1p is predominantly localized to lipid droplets. Lpx1p as well as Ldh1p comprises the typical GXSXG-type lipase motif of members of the α/β-hydrolase family. Both proteins carry a putative peroxisomal targeting signal type-1 (PTS1) and can ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).