On the Morphology of the Drosophila Heart
... Abstract: The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to na ...
... Abstract: The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to na ...
Pseudolaric Acid B Induced Cell Cycle Arrest, Au
... inhibiory activity in vitro in various tumor lines through apoptosis [1-4], such as in human breast cancer MCF-7 cells, it was found that PAB induced cell apoptosis, cell cycle arrest and senescence [5, 6]. But in murine fibrosarcoma L929, PAB did not induce apoptosis, but autophagy [7], therefore i ...
... inhibiory activity in vitro in various tumor lines through apoptosis [1-4], such as in human breast cancer MCF-7 cells, it was found that PAB induced cell apoptosis, cell cycle arrest and senescence [5, 6]. But in murine fibrosarcoma L929, PAB did not induce apoptosis, but autophagy [7], therefore i ...
Fig. - Journal of Cell Science
... flagellar pocket (Fig. 2B) and kDNA segregation occurred (Fig. 1C3,C4). The volume of the mitochondrial DNA density of the kinetoplast increased significantly at stage 2 when kinetoplast S-phase occurred, reaching a maximum in stage 3 (these measurements included the nabelschnur in stage 3) (Fig. 3) ...
... flagellar pocket (Fig. 2B) and kDNA segregation occurred (Fig. 1C3,C4). The volume of the mitochondrial DNA density of the kinetoplast increased significantly at stage 2 when kinetoplast S-phase occurred, reaching a maximum in stage 3 (these measurements included the nabelschnur in stage 3) (Fig. 3) ...
4. Fertilize eggs as described in the basic protocol
... Sea urchin development progresses in a predictable and easily observable way (Gilbert, 2000). The vegetal plate thickens and primary mesenchyme cells ingress and form spicules, the urchin skeleton (Figure 1). Then, the vegetal plate invaginates, forming the archenteron, and this archenteron migrates ...
... Sea urchin development progresses in a predictable and easily observable way (Gilbert, 2000). The vegetal plate thickens and primary mesenchyme cells ingress and form spicules, the urchin skeleton (Figure 1). Then, the vegetal plate invaginates, forming the archenteron, and this archenteron migrates ...
Size, shape, and arrangement of native cellulose fibrils in maize cell
... terms, the cellulose elementary fibril (CEF) as the nascent fibril synthesized by the cellulose synthase rosettes, and the macrofibril as a bundle of CEFs, both contain only cellulose. The microfibril as a morphological unit often observed by microscopy may contain a single CEF or a small macrofibri ...
... terms, the cellulose elementary fibril (CEF) as the nascent fibril synthesized by the cellulose synthase rosettes, and the macrofibril as a bundle of CEFs, both contain only cellulose. The microfibril as a morphological unit often observed by microscopy may contain a single CEF or a small macrofibri ...
Yersinia pestis targets neutrophils via complement receptor 3
... Introduction Many bacteria assemble nanomachines on their surfaces to deliver protein cargo to specific destinations. In Gramnegative bacteria, type III secretion systems (T3SS) are often engaged to deliver bacterial proteins into eukaryotic cells in a process that involves assembly of a needle-like ...
... Introduction Many bacteria assemble nanomachines on their surfaces to deliver protein cargo to specific destinations. In Gramnegative bacteria, type III secretion systems (T3SS) are often engaged to deliver bacterial proteins into eukaryotic cells in a process that involves assembly of a needle-like ...
Pattern formation during gastrulation in the sea urchin embryo
... lose their ability to change fate as shown experimentally by a loss of an ability to become skeleton-producing cells (Ettensohn and McClay, 1988; Ettensohn, 1990a). The secondary mesenchyme cells then enter a complicated migratory and differentiation pathway to give rise to the coelomic pouches, eso ...
... lose their ability to change fate as shown experimentally by a loss of an ability to become skeleton-producing cells (Ettensohn and McClay, 1988; Ettensohn, 1990a). The secondary mesenchyme cells then enter a complicated migratory and differentiation pathway to give rise to the coelomic pouches, eso ...
final1-fp7-people-ief-2015-huber-final-report-02
... increasingly regarded as a central element for many cellular key processes including cell division, cell migration, and adhesion. Several specific actin-MT linker molecules have been discovered, but a detailed understanding of their effects on actin-MT co-organization remains elusive. For a more pro ...
... increasingly regarded as a central element for many cellular key processes including cell division, cell migration, and adhesion. Several specific actin-MT linker molecules have been discovered, but a detailed understanding of their effects on actin-MT co-organization remains elusive. For a more pro ...
Identification of the Tuberous Sclerosis Complex
... lipid kinases catalyze the production of the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-3, 4P2) and phosphatidylinositol-3,4,5-trisphosphate (PtdIns3,4,5P3; reviewed by Katso et al., 2001; Rameh and Cantley, 1999). Downstream targets containing specialized domains, such as pleck ...
... lipid kinases catalyze the production of the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-3, 4P2) and phosphatidylinositol-3,4,5-trisphosphate (PtdIns3,4,5P3; reviewed by Katso et al., 2001; Rameh and Cantley, 1999). Downstream targets containing specialized domains, such as pleck ...
Parotid gland – Anatomy & tumours
... Mucoepidermoid carcinoma •Most common primary parotid gland malignancy, and second to adenoid cystic carcinoma in the other salivary glands •Most commonly occurs in 5th decade of life, but also most common salivary gland tumour in children •F:M = 2.4:1 •Arise from basal cells of the ...
... Mucoepidermoid carcinoma •Most common primary parotid gland malignancy, and second to adenoid cystic carcinoma in the other salivary glands •Most commonly occurs in 5th decade of life, but also most common salivary gland tumour in children •F:M = 2.4:1 •Arise from basal cells of the ...
Experimental approaches to study plant cell walls during plant
... polarized protein secretion) with cell wall-associated defense responses (Bartetzko et al., 2009). Similarly, but for a plant protein, the application of spinning disk confocal microscopy allowed the visualization of the CELLULOSE SYNTHASE (CeSA) complexes after exposure to the dinitrite-peptide Tha ...
... polarized protein secretion) with cell wall-associated defense responses (Bartetzko et al., 2009). Similarly, but for a plant protein, the application of spinning disk confocal microscopy allowed the visualization of the CELLULOSE SYNTHASE (CeSA) complexes after exposure to the dinitrite-peptide Tha ...
A novel giant peroxisomal superoxide dismutase motif
... peroxidase were generated by random priming using the Megaprime DNA labeling system (Amersham Pharmacia Biotech). For the generation of the templates, fragments of the respective cDNAs were amplified from mouse brain cDNA using the following specific primers: 5′-ACCACAGTCCATGCCATCAC-3′ and 5′-TCCACCAC ...
... peroxidase were generated by random priming using the Megaprime DNA labeling system (Amersham Pharmacia Biotech). For the generation of the templates, fragments of the respective cDNAs were amplified from mouse brain cDNA using the following specific primers: 5′-ACCACAGTCCATGCCATCAC-3′ and 5′-TCCACCAC ...
Protein Dynamics II - UAB School of Optometry
... there’s a mutation that occurs there that makes that cavity a little hydrophilic and water comes into that cavity, the water molecule can take the place of the nitrogen atom on the histidine side chain and essentially cause the porphyrin ring with its iron to leave the cavity, float out, go to the c ...
... there’s a mutation that occurs there that makes that cavity a little hydrophilic and water comes into that cavity, the water molecule can take the place of the nitrogen atom on the histidine side chain and essentially cause the porphyrin ring with its iron to leave the cavity, float out, go to the c ...
Peptide signalling during angiosperm seed
... two predictions, which we feel could emerge from consideration of the situation outlined above. First, we propose that the fact that the concomitant development of the embryo and endosperm evolved from a situation in which their development was effectively independent (as in gymnosperms) may mean th ...
... two predictions, which we feel could emerge from consideration of the situation outlined above. First, we propose that the fact that the concomitant development of the embryo and endosperm evolved from a situation in which their development was effectively independent (as in gymnosperms) may mean th ...
Identifying the causal role of a new adipose tissue signalling
... We have established, in recent years, the Oxford CABG Bioresource (OCB),2-5 which builds a unique, very well characterised cohort of patients undergoing cardiac surgery and stores a wide range of tissue samples, including various types of adipose tissue, human vessels, myocardial samples and others. ...
... We have established, in recent years, the Oxford CABG Bioresource (OCB),2-5 which builds a unique, very well characterised cohort of patients undergoing cardiac surgery and stores a wide range of tissue samples, including various types of adipose tissue, human vessels, myocardial samples and others. ...
Message in a bottle: small signalling peptide
... while over 1000 putative small signalling peptide sequences can be recognized (Lease and Walker, 2006). There are several ways to explain this seeming overabundance of putative small signalling peptides. First, as receptors commonly form complexes, it may be that interacting proteins are able to alt ...
... while over 1000 putative small signalling peptide sequences can be recognized (Lease and Walker, 2006). There are several ways to explain this seeming overabundance of putative small signalling peptides. First, as receptors commonly form complexes, it may be that interacting proteins are able to alt ...
Cyclin synthesis and degradation and the embryonic cell cycle
... failed to repair D N A damage to pass through mitosis (and in doing so kill themselves; Weinert and Hartwell, 1988), while tissue culture cells that are arrested in S phase can be induced to enter mitosis by treatment with caffeine (Schlegel and Pardee, 1986). ...
... failed to repair D N A damage to pass through mitosis (and in doing so kill themselves; Weinert and Hartwell, 1988), while tissue culture cells that are arrested in S phase can be induced to enter mitosis by treatment with caffeine (Schlegel and Pardee, 1986). ...
Mechanisms of cellular communication through intercellular protein
... protein bride of sevenless is internalized from one cell by contact with another during eye development in Drosophila melanogaster [66]. The mechanisms for above mentioned protein transfers are different from the topic of this review. Interestingly, transfer of CD9 tetraspin, a membrane-organizing m ...
... protein bride of sevenless is internalized from one cell by contact with another during eye development in Drosophila melanogaster [66]. The mechanisms for above mentioned protein transfers are different from the topic of this review. Interestingly, transfer of CD9 tetraspin, a membrane-organizing m ...
Fuel Cell book.indd
... been taught or should be expected to know, but to assess what they understand so far about how a PEM fuel cell works. It serves as a baseline assessment, for comparison with the knowledge they display at the end of the challenge, in their final presentation, as well as on the post-test. 1. Distribu ...
... been taught or should be expected to know, but to assess what they understand so far about how a PEM fuel cell works. It serves as a baseline assessment, for comparison with the knowledge they display at the end of the challenge, in their final presentation, as well as on the post-test. 1. Distribu ...
Isolation of Chinese Hamster Ovary Cell Mutants Requiring the
... conditions for its growth have been previously described (8). Mutant isolation from UV-mutagenized ceils was carried out as in an earlier study (6), except that 0.3 ug/ml of taxol was used as the selecting drug concentration. Surviving colonies, which arose at a frequency of 10-5, were picked into t ...
... conditions for its growth have been previously described (8). Mutant isolation from UV-mutagenized ceils was carried out as in an earlier study (6), except that 0.3 ug/ml of taxol was used as the selecting drug concentration. Surviving colonies, which arose at a frequency of 10-5, were picked into t ...
Guidance of mesoderm cell migration in the Xenopus
... animal pole region (Nakatsuji and Johnson, 1983b). In Xenopus, migration in vitro is also directional, although only when aggregates of mesodermal cells are used to probe conditioned substratum, instead of single cells (Fig. 1A). Moreover, in the Xenopus embryo, anterior mesoderm cells extend locomo ...
... animal pole region (Nakatsuji and Johnson, 1983b). In Xenopus, migration in vitro is also directional, although only when aggregates of mesodermal cells are used to probe conditioned substratum, instead of single cells (Fig. 1A). Moreover, in the Xenopus embryo, anterior mesoderm cells extend locomo ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).