Extramedullary Chitosan Channels Promote Survival
... after complete SCT. However, the bridges were small and contained few regenerating axons.15–17 There were also side effects, including caudal migration of the rostral stump and syringomyelia, possibly due to subarachnoid scarring. Currently, we are focusing on channels composed of chitosan, a biodeg ...
... after complete SCT. However, the bridges were small and contained few regenerating axons.15–17 There were also side effects, including caudal migration of the rostral stump and syringomyelia, possibly due to subarachnoid scarring. Currently, we are focusing on channels composed of chitosan, a biodeg ...
Phosphatidylserine, a death knell
... as the thickness of the hydrophobic core1 or local lateral domains of specialized lipid composition2 ± 4 may play significant roles in the assembly and organization of cellular membranes. In addition to these structural contributions to membrane function, the past few years have also seen the revela ...
... as the thickness of the hydrophobic core1 or local lateral domains of specialized lipid composition2 ± 4 may play significant roles in the assembly and organization of cellular membranes. In addition to these structural contributions to membrane function, the past few years have also seen the revela ...
Heavy Metals and Metalloids As a Cause for Protein Misfolding and
... generate reactive oxygen species and to elicit oxidative stress; (2) to cause DNA damage and/or impair DNA repair mechanisms; (3) to interfere with membrane function and nutrient assimilation; and (4) to perturb protein function and activity [3–5]. At the molecular level, our understanding of how he ...
... generate reactive oxygen species and to elicit oxidative stress; (2) to cause DNA damage and/or impair DNA repair mechanisms; (3) to interfere with membrane function and nutrient assimilation; and (4) to perturb protein function and activity [3–5]. At the molecular level, our understanding of how he ...
The first cell fate specification event in mouse development
... nucleus is hyperacetylated and hypomethylated, two features that allow for higher accessibility to transcription factors and transcriptional activation (Hamatani et al., 2004; Li et al., 2010; Sch ...
... nucleus is hyperacetylated and hypomethylated, two features that allow for higher accessibility to transcription factors and transcriptional activation (Hamatani et al., 2004; Li et al., 2010; Sch ...
Functional specialization of Medicago truncatula leaves and
... very eYcient retrieval to the ER (Pagny et al. 2000; Sriraman et al. 2004) while in other cases some of the protein escapes the retrieval mechanism and passes through the Golgi (Ko et al. 2003; Triguero et al. 2005). Saturation of the KDEL receptor has also been demonstrated (Crofts et al. 1999). In ...
... very eYcient retrieval to the ER (Pagny et al. 2000; Sriraman et al. 2004) while in other cases some of the protein escapes the retrieval mechanism and passes through the Golgi (Ko et al. 2003; Triguero et al. 2005). Saturation of the KDEL receptor has also been demonstrated (Crofts et al. 1999). In ...
Histology Lab Manual - Histology Laboratory Manual
... matrix). It is for this reason that we emphasize the basic components of cells and their matrices during the early portion of the course. With an understanding of the nature of the relationship between cells and their matrices, we can proceed to the study of the organization of these two components ...
... matrix). It is for this reason that we emphasize the basic components of cells and their matrices during the early portion of the course. With an understanding of the nature of the relationship between cells and their matrices, we can proceed to the study of the organization of these two components ...
Coupled elasticity–diffusion model for the effects of cytoskeleton
... cells, therefore, their interaction with the cytoskeleton is unavoidable. Obataya et al. [9] used an atomic force microscope with a long nanoneedle (radius ¼ 1002150 nm) to indent living cells. They demonstrated that the loading force curve for an indentation depth of up to 2 mm is still consistent ...
... cells, therefore, their interaction with the cytoskeleton is unavoidable. Obataya et al. [9] used an atomic force microscope with a long nanoneedle (radius ¼ 1002150 nm) to indent living cells. They demonstrated that the loading force curve for an indentation depth of up to 2 mm is still consistent ...
anatomy of begonia lucernae wettst. (begoniaceae) leaf
... patterns and textures in their leaves rarely seen in other groups of plants. Sheue et al. (2012) concluded that the variegation is structural, like the intracellular space, where the light areas were created by internal reflection between the intercellular spaces. The intracellular space may occur b ...
... patterns and textures in their leaves rarely seen in other groups of plants. Sheue et al. (2012) concluded that the variegation is structural, like the intracellular space, where the light areas were created by internal reflection between the intercellular spaces. The intracellular space may occur b ...
Growth-factor-related proteins that are inducers in early
... of incubation medium I, consisting of 50% Liebovitz serumfree tissue culture medium and 50% D2/D3, with effective EDTA concentration adjusted so as to give a loose, open texture to tissue rather than rounding up into balls bounded by the original upper epiblast surface (usually ca. 0.6mM EDTA overal ...
... of incubation medium I, consisting of 50% Liebovitz serumfree tissue culture medium and 50% D2/D3, with effective EDTA concentration adjusted so as to give a loose, open texture to tissue rather than rounding up into balls bounded by the original upper epiblast surface (usually ca. 0.6mM EDTA overal ...
T Cells + Memory CD8 Influenza A Virus
... apid, efficient clearance of respiratory virus infections (1) requires TCR-mediated recognition of viral peptides bound to MHC class I glycoproteins. Following TCR engagement and activation of the signaling cascade, virus-specific CD8⫹ CTLs undergo a program of proliferation and differentiation as t ...
... apid, efficient clearance of respiratory virus infections (1) requires TCR-mediated recognition of viral peptides bound to MHC class I glycoproteins. Following TCR engagement and activation of the signaling cascade, virus-specific CD8⫹ CTLs undergo a program of proliferation and differentiation as t ...
In Vitro Toxicology and Cellular Fate Determination Using
... cultures, the Biomek® 2000 workstation dispensed the CellTiter-Glo™ Reagent and then agitated the plates for two minutes on the integrated shaker. Plates were incubated for 10 minutes in the dark at room temperature before being read on an EG&G MicroLumat Luminometer. Apo-ONE™ Assays of staurosporin ...
... cultures, the Biomek® 2000 workstation dispensed the CellTiter-Glo™ Reagent and then agitated the plates for two minutes on the integrated shaker. Plates were incubated for 10 minutes in the dark at room temperature before being read on an EG&G MicroLumat Luminometer. Apo-ONE™ Assays of staurosporin ...
Full text - 2nd International Conference of the
... observations should earn a place for himself in the pantheon of distinguished plant scientists. Botany students learn about these connections, which have been found in all classes of plants and plant tissues, under the name given to them, ―plasmodesmata‖, by Strasburger in 1901.15 The full elucidati ...
... observations should earn a place for himself in the pantheon of distinguished plant scientists. Botany students learn about these connections, which have been found in all classes of plants and plant tissues, under the name given to them, ―plasmodesmata‖, by Strasburger in 1901.15 The full elucidati ...
OCTOPUS, a polarly localised membrane
... indicating that auxin-independent factors also play a role in this process (Candela et al., 1999; Carland et al., 1999; Carland et al., 2002). Notably, vascular development is embedded into a developmental context, as the formation of vascular strands usually occurs in growing tissues. In leaves, fo ...
... indicating that auxin-independent factors also play a role in this process (Candela et al., 1999; Carland et al., 1999; Carland et al., 2002). Notably, vascular development is embedded into a developmental context, as the formation of vascular strands usually occurs in growing tissues. In leaves, fo ...
Role of E-cadherin and other cell adhesion molecules in survival
... and pluripotent states has expanded considerably during the past 14 years. Key transcription factors, including Oct4, Sox2 and Nanog, have been found to act in autoregulatory modules to specify the pluripotent state of both mouse and human pluripotent stem cells.9 Other regulatory cues, such as supp ...
... and pluripotent states has expanded considerably during the past 14 years. Key transcription factors, including Oct4, Sox2 and Nanog, have been found to act in autoregulatory modules to specify the pluripotent state of both mouse and human pluripotent stem cells.9 Other regulatory cues, such as supp ...
Induction of a Secondary Body Axis in Xenopus by Antibodies to
... restored a compact epithelial morphology. Epithelial compaction is thought to depend on the actin cytoskeleton (15), consistent with a cytoskeletal linker function for ot-catenin. The function of/3-catenin in the cadherin complex is less clear./3-Catenin binds directly to the cadherin cytoplasmic ta ...
... restored a compact epithelial morphology. Epithelial compaction is thought to depend on the actin cytoskeleton (15), consistent with a cytoskeletal linker function for ot-catenin. The function of/3-catenin in the cadherin complex is less clear./3-Catenin binds directly to the cadherin cytoplasmic ta ...
Full-Text PDF
... a model based on the antagonistic role of auxin and cytokinin [58] reproduced visual and kinematic observations, such as the expected increase and decrease in the size of the meristem upon addition of auxin and cytokinin [59]. This suggests that a cross talk between these two hormones is essential f ...
... a model based on the antagonistic role of auxin and cytokinin [58] reproduced visual and kinematic observations, such as the expected increase and decrease in the size of the meristem upon addition of auxin and cytokinin [59]. This suggests that a cross talk between these two hormones is essential f ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).