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Coupling cellular oscillators—circadian and cell division cycles in cyanobacteria Bernardo F Pando
Coupling cellular oscillators—circadian and cell division cycles in cyanobacteria Bernardo F Pando

... which the proposed pathway had been disrupted. FstZ is a conserved bacterial homolog of tubulin that is usually expressed in a ring in the middle of a cell just before it divides. Though there are probably more intermediate steps between the identified players and perhaps some other pathways might r ...
Dissociation of Centrosome Replication Events from Cycles of DNA
Dissociation of Centrosome Replication Events from Cycles of DNA

... centrosome replication that have been detected in embryonic cells after various experimental treatments most likely occurred by recruitment of precursor components from the preexisting cytoplasmic pools of proteins in eggs. It seems unlikely that cycling somatic cells have large amounts of stored pr ...
PD-1 promotes immune exhaustion by inducing antiviral T cell
PD-1 promotes immune exhaustion by inducing antiviral T cell

... versus persistent infection. (A) TPM was used to examine the dynamics of CD8+ P14 (red) and CD4+ SMARTA (green) T cells in the spleen after an acute (Arm) or a persistent (CL13) infection (n = 5 mice). Representative 3D reconstructions of two-photon z stacks are shown for infected mice at day 7 afte ...
Detoxification of Arsenic by Phytochelatins in Plants
Detoxification of Arsenic by Phytochelatins in Plants

... ration of As into organic molecules by the formation of e.g. arsenocholine, arsenobetaine, or arsenosugars. In bacteria, a widespread tolerance mechanism for arsenate, AsVO43⫺, is based on an efflux system that exports arsenic specifically and ATP-dependently as AsIIIO2⫺ from the cell generated by c ...
Lineage-restricted neural precursors survive, migrate, and
Lineage-restricted neural precursors survive, migrate, and

... Fetal spinal cord from embryonic day 14 (E14/FSC) has been used for numerous transplantation studies of injured spinal cord. E14/FSC consists primarily of neuronal (NRP)- and glial (GRP)-restricted precursors. Therefore, we reasoned that comparing the fate of E14/FSC with defined populations of line ...
Arabidopsis ORGAN SIZE RELATED1 regulates organ growth and
Arabidopsis ORGAN SIZE RELATED1 regulates organ growth and

... In Arabidopsis leaves, most cells begin to undergo cell expansion when cell proliferation arrests gradually from leaf tip to base; however, there are still some cells that maintain the meristematic competence to continue dividing and form the specific cell type within each cell layer (Donnelly et al ...
Factors that influence the interaction of Campylobacter jejuni with
Factors that influence the interaction of Campylobacter jejuni with

... * Department of Veterinary Science, University of Arizona, Tucson, A2 85727, USA ...
1749-8104-8-5 - Cambridge Repository
1749-8104-8-5 - Cambridge Repository

... program of these cells would continue in ectopic locations, we used donor neural plate cells from the tg(HuCGFP) line, in which all neurons express GFP [15]. The neural tube of a 28 hpf wild-type embryo is organized with neurons differentiating at the basal edge and ZO-1 immunoreactivity lining the ...
Introduction and Epithelial Tissues
Introduction and Epithelial Tissues

... Epithelia are usually classified according their structure, their location, or their organization into glands (glandular epithelia.) – Classification according to structure is based upon the (1) shape of the cells at the free surface and the (2) number of cell layers of the epithelial membrane. – Cl ...
Senescence-Associated Vacuoles, a Specific Lytic Compartment for
Senescence-Associated Vacuoles, a Specific Lytic Compartment for

... senescing wheat leaves [33,34]. RCBs were first described as small (0.4–1.2 µm in diameter), double membrane bound vesicles detected in the cytosol of leaf cells through transmission electron microscopy [33]. Their numbers increased during senescence, and immunolocalization experiments showed that t ...
Inactivation of Photosystems I and II in Response
Inactivation of Photosystems I and II in Response

Auxin-Dependent Cell Division and Cell Elongation. 1
Auxin-Dependent Cell Division and Cell Elongation. 1

... developmental programs. In both cases, plant hormones coordinate adaptive changes in cellular division and differentiation. Auxins control several fundamental aspects of the plant development, such as cell expansion, cell division, pattern formation, root development, and apical dominance, and also ...
Minimal Time Requirement for Lasting Elicitor Effects in
Minimal Time Requirement for Lasting Elicitor Effects in

... cells are unable to control the efflux of various so­ lutes to the invading fungus. Biotrophic fungi depend on the solute drain from the host cells and may take up a large percentage of the plant's total assimilates [2]. Very probably, modulation of the host plas­ malemma ATPase activity is a key fa ...
Analysis of the paralysed trypanosome mutant snl-1
Analysis of the paralysed trypanosome mutant snl-1

... posterior end of the cell. The flagellum is attached throughout most of its length to a region of the cell body termed the flagellum attachment zone (Kohl and Gull, 1998). The basal body of the flagellum is tightly connected to the kinetoplast, the condensed DNA of the single mitochondrion (Robinson ...
making endothelial cells move – a study of angiomotin and
making endothelial cells move – a study of angiomotin and

... [11]. Some claim CAFs to originate from bone-marrow progenitor cells, others say they are local tissue-derived fibroblasts and there are also reports of transdifferentiating epithelial cells [12-15]. Studies on CAFs have mostly been conducted by co-injecting them together with tumor cells into mice ...
Transport of proteins across mitochondrial membranes
Transport of proteins across mitochondrial membranes

... are incompetent for import of most but not all preproteins, in particular of those containing N-terminal extensions [22]. Mitochondria in the mutant cells have lost the cristae membranes and their membrane bound cytochromes. MOM19 is thus an important although not essential component of the import m ...
Inducing Embryonic Stem Cells to Become
Inducing Embryonic Stem Cells to Become

... ICM derivatives exhibiting a very dense, refractile morphology. Clusters of refractile cells were then physically isolated, dispersed, and replated onto MEF feeder layers. This process was repeated until clonal ESC lines were established (Fig. 1e). Mouse ESC lines can be propagated extensively in an ...
Emerging regulatory mechanisms in ubiquitin
Emerging regulatory mechanisms in ubiquitin

... we will review these emerging regulatory mechanisms of ubiquitin-dependent cell cycle control. In addition, we will discuss how cells utilize these processes to accomplish their most important task – the accurate distribution of genomic material to their progeny. Diversity: new signals in cell cycle ...
Antiproliferative and apoptotic effects of O
Antiproliferative and apoptotic effects of O

Simvastatin Reduces MMP1 Expression in Human Smooth Muscle
Simvastatin Reduces MMP1 Expression in Human Smooth Muscle

Computational Models Reveal a Passive Mechanism for Cell
Computational Models Reveal a Passive Mechanism for Cell

... robust, and not model-dependent. ...
PDF
PDF

... medium, 7-ketocholesterol, cholesterol, concanavalin A, anti-embryonal carcinoma antiserum and tunicamycin) which modify the cell membrane and/or cytoskeleton were used to investigate the molecular and cellular basis of the intercellular and intracellular components of compaction and analyse the rel ...
Expression of the RET Receptor Tyrosine Kinase and GDNFR
Expression of the RET Receptor Tyrosine Kinase and GDNFR

Optimization of ERK Activity Biosensors for both Ratiometric and
Optimization of ERK Activity Biosensors for both Ratiometric and

... thus corresponds to an increase of kinase activity and vice versa [10]. The lifetime of the donor fluorophore is also affected by a FRET event and decreases upon kinase activity. The purpose of optimizing such tools directly relies on kinase activity behavior. In fact, in some biological processes, ...
Full Text
Full Text

... development. Embryos of different developmental stages {Hamburger and Hamilton, 1951 J were m Vitro labeled with 35S-methionine for 1 h. Prosomes were purd'edas described in Matenals and Methods. Proteins were ana/ysed by 50S PAGE and fluorographed. (A-F) F/uorograms of the pro rein gels of the grad ...
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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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