Immunity Hemopoiesis and Cellular Drosophila
... missing-2 (Gcm2) (14 –16). In the absence of both these transcription factors, plasmatocytes fail to differentiate normally, and their number is reduced severely, whereas crystal cell formation appears unaffected (16). Previously, it was thought that during their differentiation crystal cells must e ...
... missing-2 (Gcm2) (14 –16). In the absence of both these transcription factors, plasmatocytes fail to differentiate normally, and their number is reduced severely, whereas crystal cell formation appears unaffected (16). Previously, it was thought that during their differentiation crystal cells must e ...
Compounds from Wild Mushrooms with Antitumor
... Czech Republic as a functional food for the treatment of rectal cancer [19]. Compound 24 was also isolated from Daedalea dickinsii. MMPs mediate physiological extracellular matrix remodelling and have been implicated in several pathological processes including tumor growth and metastasis [37]. In hu ...
... Czech Republic as a functional food for the treatment of rectal cancer [19]. Compound 24 was also isolated from Daedalea dickinsii. MMPs mediate physiological extracellular matrix remodelling and have been implicated in several pathological processes including tumor growth and metastasis [37]. In hu ...
BiochemicalSociety A nnualSymposium No.77
... and ultimately plant morphology, is accomplished by the polarized targeting and localized release of secretorypathway-derived membrane and cell wall material at specific sites on the PM. Directional cell expansion in plants occurs through two distinct mechanisms: diffuse polar and tip growth [12], w ...
... and ultimately plant morphology, is accomplished by the polarized targeting and localized release of secretorypathway-derived membrane and cell wall material at specific sites on the PM. Directional cell expansion in plants occurs through two distinct mechanisms: diffuse polar and tip growth [12], w ...
Lymphoma Vaccines for Active Immunotherapy of T Cell Are More
... The ability to target multiple tumor Ags may increase the magnitude and diversity of anti-tumor responses, thus preventing tumor from escaping responses limited in repertoire (30). Loading DC with proteins from tumor cell lysates may result in the presentation of a broader array of tumor-specific Ag ...
... The ability to target multiple tumor Ags may increase the magnitude and diversity of anti-tumor responses, thus preventing tumor from escaping responses limited in repertoire (30). Loading DC with proteins from tumor cell lysates may result in the presentation of a broader array of tumor-specific Ag ...
Microtubules and Microfilaments in Cell
... can also be controlled through selective stabilization of microtubules. A putative stabilizer of microtubules has recently been identified with the cloning of the MICROTUBULE ORGANIZATION 1 (MOR1) gene in Arabidopsis. MOR1 encodes a homologue of the TOGp–XMAP215 class of microtubule-associated prote ...
... can also be controlled through selective stabilization of microtubules. A putative stabilizer of microtubules has recently been identified with the cloning of the MICROTUBULE ORGANIZATION 1 (MOR1) gene in Arabidopsis. MOR1 encodes a homologue of the TOGp–XMAP215 class of microtubule-associated prote ...
Supplementary Methods
... (dH2O) was a negative control with no PCR template. (b) TTGE analysis of p15 demethylation at varying doses of 5-Aza-dC (0 – 8 M). Amplicon contains 30 CpG sites and differentially methylated sequences were resolved according to differences in melting temperature. Previously characterized KG1a (>95 ...
... (dH2O) was a negative control with no PCR template. (b) TTGE analysis of p15 demethylation at varying doses of 5-Aza-dC (0 – 8 M). Amplicon contains 30 CpG sites and differentially methylated sequences were resolved according to differences in melting temperature. Previously characterized KG1a (>95 ...
Expression of the Activating Transcription Factor 3 Prevents c
... as an activator of specific promoters in non-neuronal cells (Hsu et al., 1992; Hai and Hartman, 2001). c-Jun, which is another member of the CREB/ATF family, is also known as a stress-inducible gene in both neuronal and non-neuronal cells. c-Jun is activated by c-Jun N-terminal kinase/stress-activat ...
... as an activator of specific promoters in non-neuronal cells (Hsu et al., 1992; Hai and Hartman, 2001). c-Jun, which is another member of the CREB/ATF family, is also known as a stress-inducible gene in both neuronal and non-neuronal cells. c-Jun is activated by c-Jun N-terminal kinase/stress-activat ...
Tumor-specific T cells in human Merkel cell carcinomas: a possible
... are imprinted with expression of tissue specific addressins and preferentially migrate to the peripheral tissue in which they first encountered antigen (Campbell and Butcher, 2002; Kupper and Fuhlbrigge, 2004). MCC-specific T cells should express the skin-homing addressin CLA because MCC are cutaneo ...
... are imprinted with expression of tissue specific addressins and preferentially migrate to the peripheral tissue in which they first encountered antigen (Campbell and Butcher, 2002; Kupper and Fuhlbrigge, 2004). MCC-specific T cells should express the skin-homing addressin CLA because MCC are cutaneo ...
The Sinorhizobium meliloti sensor histidine kinase
... in the frequency of DivK polar localization (Van der Henst et al., 2012). The growth arrest due to pdhS loss of function is not associated with altered cell morphology (Van der Henst et al., 2012), but overexpression of PdhS does produce a filamentous cell growth phenotype (Hallez et al., 2007; Van ...
... in the frequency of DivK polar localization (Van der Henst et al., 2012). The growth arrest due to pdhS loss of function is not associated with altered cell morphology (Van der Henst et al., 2012), but overexpression of PdhS does produce a filamentous cell growth phenotype (Hallez et al., 2007; Van ...
Scanned by CamScanner
... ELF3 (also called ESX, ERT, ESE-1, EPR-1, JEN) is a member of the E26 transformation specific (ETS) family of transcription factors. These transcription factors are so named because they share a highly conserved DNA binding domain named the ETS domain (Fig. 2). These factors can be further divided i ...
... ELF3 (also called ESX, ERT, ESE-1, EPR-1, JEN) is a member of the E26 transformation specific (ETS) family of transcription factors. These transcription factors are so named because they share a highly conserved DNA binding domain named the ETS domain (Fig. 2). These factors can be further divided i ...
Mouse embryonic stem cells can differentiate via multiple
... including Otx2, Otx1, Crx, Six1, Dmrta2, Zic1, and Zic3 at the same stringency, despite the absence of MNs in the forebrain of embryos. Anterior gene expression was previously observed through bulk measurements of DP3, and our results reveal that it occurs within a specific subpopulation of cells ...
... including Otx2, Otx1, Crx, Six1, Dmrta2, Zic1, and Zic3 at the same stringency, despite the absence of MNs in the forebrain of embryos. Anterior gene expression was previously observed through bulk measurements of DP3, and our results reveal that it occurs within a specific subpopulation of cells ...
Intersections of lung progenitor cells, lung disease and lung cancer
... stem-like cells in solid tumours emerged nearly a decade later. At that time it was unknown if other types of tumour were driven by progenitor-like cells and, if so, what possible vulnerabilities cancer stem cells could reveal as new therapeutic targets. Much as for normal lung progenitor cells, met ...
... stem-like cells in solid tumours emerged nearly a decade later. At that time it was unknown if other types of tumour were driven by progenitor-like cells and, if so, what possible vulnerabilities cancer stem cells could reveal as new therapeutic targets. Much as for normal lung progenitor cells, met ...
A NIMA-related kinase, Cnk2p, regulates both
... During interphase, Fa2p localizes to the proximal end of the flagella, whereas during mitosis it is associated with the polar region of the mitotic spindle (Mahjoub et al., 2004). This was the first report of a NIMA-related kinase with both cell cycle and ciliary functions; Cnk2p is the second. NIMA ...
... During interphase, Fa2p localizes to the proximal end of the flagella, whereas during mitosis it is associated with the polar region of the mitotic spindle (Mahjoub et al., 2004). This was the first report of a NIMA-related kinase with both cell cycle and ciliary functions; Cnk2p is the second. NIMA ...
Formation of the leading edge boundary
... abuts the amnioserosa directly (see Fig. 4A). This differs from cells of the rest of the dorsal ectoderm that localize Fasciclin III cortically. Finally, in some experiments, we have used dpp transcripts to confirm the fate of LE cells. Since dpp gene expression is not exclusively restricted to LE c ...
... abuts the amnioserosa directly (see Fig. 4A). This differs from cells of the rest of the dorsal ectoderm that localize Fasciclin III cortically. Finally, in some experiments, we have used dpp transcripts to confirm the fate of LE cells. Since dpp gene expression is not exclusively restricted to LE c ...
Contract Monoclonal Antibody Production
... A cell line is comprised of a large population of cells. Over time, mutations occur within the population. Some mutations give rise to virulent, non-antibody producing cells which threaten the security of the cell line if they are permitted to grow. This condition, which is representative of one of ...
... A cell line is comprised of a large population of cells. Over time, mutations occur within the population. Some mutations give rise to virulent, non-antibody producing cells which threaten the security of the cell line if they are permitted to grow. This condition, which is representative of one of ...
BCL-6 regulates chemokine gene transcription in macrophages
... Heart tissue from TCRα–/– BCL-6–/– mice and wild-type mice had no detectable chemokine expression measured by RPA and only trace MRP-1 detected by RT-PCR (Fig. 5). The background level of MRP-1 was similar between the wild-type and the TCRα–/– BCL-6–/– hearts, and thus BCL-6 does not appear to regul ...
... Heart tissue from TCRα–/– BCL-6–/– mice and wild-type mice had no detectable chemokine expression measured by RPA and only trace MRP-1 detected by RT-PCR (Fig. 5). The background level of MRP-1 was similar between the wild-type and the TCRα–/– BCL-6–/– hearts, and thus BCL-6 does not appear to regul ...
Cell growth and differentiation in Arabidopsis
... TRY in promoting endoreduplication remains unknown. ...
... TRY in promoting endoreduplication remains unknown. ...
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... (Fig. 2A,B), a signature that is characteristic of a population of cells that have been suggested to act as a precursor of the spinal cord and the paraxial mesoderm in the embryo, the neuromesodermal axial precursor (NMp) (reviewed by Wilson et al., 2009; Kondoh and Takemoto, 2012). Addition of SB43 ...
... (Fig. 2A,B), a signature that is characteristic of a population of cells that have been suggested to act as a precursor of the spinal cord and the paraxial mesoderm in the embryo, the neuromesodermal axial precursor (NMp) (reviewed by Wilson et al., 2009; Kondoh and Takemoto, 2012). Addition of SB43 ...
What the Distribution of Cell Lengths in the Root Meristem Does and
... mitotic sisters was rarely more than 10% of the sisters' mean length; similarly, the difference in length between mitotic neighbors (that is, mitotic cells in a ®le that are adjacent but not sisters) was also small (less than 14%). This shows that the cell cycle departs markedly from a constant dura ...
... mitotic sisters was rarely more than 10% of the sisters' mean length; similarly, the difference in length between mitotic neighbors (that is, mitotic cells in a ®le that are adjacent but not sisters) was also small (less than 14%). This shows that the cell cycle departs markedly from a constant dura ...
12-N. Ohno.indd - PJM ONLINE | Polish Journal of Microbiology
... symptoms (Tada et al., 2011), indicating that the pathogenic effects of the polysaccharide component are not specific to C. albicans. In the course of our studies, we recently found a relationship between the structure of mannans from Candida species and the induction of several biological effects o ...
... symptoms (Tada et al., 2011), indicating that the pathogenic effects of the polysaccharide component are not specific to C. albicans. In the course of our studies, we recently found a relationship between the structure of mannans from Candida species and the induction of several biological effects o ...
What`s New in the Plant Cell Cycle?
... The major phase transitions of the cell cycle, G1/S and G2/M, are driven by cyclin dependent protein kinases (CDKs). Currently 152 CDKS have been identified from 41 plant species (Dudits et al. 2007). In animals, CDKs are numbered whilst plant CDKs are suffixed by Arabic letters in seven classes (A ...
... The major phase transitions of the cell cycle, G1/S and G2/M, are driven by cyclin dependent protein kinases (CDKs). Currently 152 CDKS have been identified from 41 plant species (Dudits et al. 2007). In animals, CDKs are numbered whilst plant CDKs are suffixed by Arabic letters in seven classes (A ...
What`s New in the Plant Cell Cycle?
... The major phase transitions of the cell cycle, G1/S and G2/M, are driven by cyclin dependent protein kinases (CDKs). Currently 152 CDKS have been identified from 41 plant species (Dudits et al. 2007). In animals, CDKs are numbered whilst plant CDKs are suffixed by Arabic letters in seven classes (A ...
... The major phase transitions of the cell cycle, G1/S and G2/M, are driven by cyclin dependent protein kinases (CDKs). Currently 152 CDKS have been identified from 41 plant species (Dudits et al. 2007). In animals, CDKs are numbered whilst plant CDKs are suffixed by Arabic letters in seven classes (A ...
Physico-chemical characteristics of cell walls from Arabidopsis
... To explore the structure of arabinose- and galactosecontaining polysaccharides, alcohol-insoluble material of cells grown for 4, 8, and 14 d were treated with endo(1,5)-a-L-arabinanase, a-L-arabinofuranosidase, endo-(1,4)b-D-galactanase, and b-D-galactosidase (Table 1). The endo-a-L-arabinanase rele ...
... To explore the structure of arabinose- and galactosecontaining polysaccharides, alcohol-insoluble material of cells grown for 4, 8, and 14 d were treated with endo(1,5)-a-L-arabinanase, a-L-arabinofuranosidase, endo-(1,4)b-D-galactanase, and b-D-galactosidase (Table 1). The endo-a-L-arabinanase rele ...