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Optimization of Ammonium Sulfate Concentration for Purification of
Optimization of Ammonium Sulfate Concentration for Purification of

... in many developing countries where health systems are not well equipped (Rigano and Walmsley, 2005). For use in plant molecular biofarming, the tobacco plant has several advantages over other plants, such as highly efficient transformation and regeneration, relatively short period for biomass producti ...
Early gastric cancer
Early gastric cancer

... patients with new-onset dyspepsia, over the age of 55, or those with 'alarm' features, are essential. ...
Mice transgenic for equine cyclin T1 and ELR1 are susceptible to
Mice transgenic for equine cyclin T1 and ELR1 are susceptible to

N-glycosylation and microtubule integrity are involved in apical
N-glycosylation and microtubule integrity are involved in apical

Cell Wall
Cell Wall

... Halobacterium, and some methanogens. In Halobacterium, the proteins in the wall have a high content of acidic amino acids, giving the wall an overall negative charge. The result is an unstable structure that is stabilized by the presence of large quantities of positive sodium ions that neutralize th ...
Transactivation of the Epidermal Growth Factor Receptor
Transactivation of the Epidermal Growth Factor Receptor

... survival, and tumorigenesis of highly malignant human glioblastoma cells. Because glioblastoma cells may also express other receptors for growth signals, such as the epidermal growth factor (EGF) receptor (EGFR), we investigated the role of EGFR in the signaling cascade of FPR and how two receptors ...
The role of T cells in Osteoporosis - International Journal of Clinical
The role of T cells in Osteoporosis - International Journal of Clinical

... promoted osteoclastogenesis in vivo, this subset is an auspicious therapeutic target for bone loss. Interdicting Effects of T Cells on Osteoclastogenesis On the other hand, T cells are capable of mediating anti-osteoclastogenic signals in bone turnover. Hints that this modulation may occur come from ...
Shp1 regulates T cell homeostasis by limiting IL
Shp1 regulates T cell homeostasis by limiting IL

... Figure 4.  Shp1-deficient T cells exhibit normal responses to TCR stimulation. (A) T cells were isolated from spleens, labeled with CFSE, and cultured on a 96-well plate coated with cross-linked antibodies against CD3 ± CD28. Cells were harvested 3 d later, stained for CD4 and CD8, and analyzed by f ...
CYTOCHALASIN B: ASPECTS OF PHAGOCYTOSIS IN NUTRIENT
CYTOCHALASIN B: ASPECTS OF PHAGOCYTOSIS IN NUTRIENT

... (not synthesized de novo by Tetrahymena (Kidder & Dewey, 1951)) can overcome the need for food vacuole formation both in the presence of cytochalasin B (present paper) and in the particle-free proteose peptone broth (Rasmussen, 1974). Summing up, phagocytosis can be significantly reduced in 2 ways, ...
Drosophila asymmetric division, polarity and cancer - e
Drosophila asymmetric division, polarity and cancer - e

... cells. Notably, tumours caused by one of such fly tumour suppressors (TSs), lethal giant larvae (lgl), were observed to originate from larval NBs (Gateff and Schneiderman, 1967). This and other types of tumours described in Drosophila over the years strongly suggest that failed key developmental deci ...
Betulinic Acid-induced Programmed Cell Death in
Betulinic Acid-induced Programmed Cell Death in

Developmental and functional studies of the SLC12 gene family
Developmental and functional studies of the SLC12 gene family

... in order to understand their significance in Drosophila as well as to eventually better understand ...
A Mechanosensory System Controls Cell Shape Changes During
A Mechanosensory System Controls Cell Shape Changes During

... production,9 at least in part, through myosin‑II mechanochemistry.18 Indeed, a nearly ubiquitous requirement for myosin‑II has been revealed through genetic experiments in a variety of organisms.19‑21 However, for Dictyostelium and higher metazoans, the contractile ring assembly and contraction phas ...
Regulation of the endothelial cell cycle by the ubiquitin
Regulation of the endothelial cell cycle by the ubiquitin

... from E2 to the target protein. Substrates can be modified with a single Ub or with Ub chains, but only poly-ubiquitination addresses proteins for degradation by the 26S-proteasome. In fact, monoubiquitination rather modulates growth factor endocytosis, PCNA activity during DNA-repair, and is involve ...
- Wiley Online Library
- Wiley Online Library

... XPAPC translation in vitro, but a complete inhibition was only achieved with a mixture of both. An XPAPC-ORF construct without the 50 UTR was not sensitive to either MO (Supplementary Figure 1). Similar results were obtained in vivo (H Steinbeisser, personal communication). To study CE movements, we ...
Increased Expression of Cytoskeletal, Linkage, and Extracellular
Increased Expression of Cytoskeletal, Linkage, and Extracellular

... cross-striation at the Z-level and distinct intercalated disk labeling. D, In failing myocardium, the cross-striation pattern is disturbed and desmin is accumulated in many irregularly shaped cells. Nuclei are red. ...
Cytokinesis in flowering plants: cellular process
Cytokinesis in flowering plants: cellular process

Interaction with PI3-kinase contributes to the cytotoxic activity ofApoptin S Maddika
Interaction with PI3-kinase contributes to the cytotoxic activity ofApoptin S Maddika

... cytoplasmic localization, whereas in sensitive cells, apoptin is found in the nucleus (Danen-Van Oorschot et al., 2003). Apoptin was described to be specifically phosphorylated in transformed cells by an unknown kinase, which was proposed to be important for the nuclear localization and apoptotic act ...
Primitive streak mesoderm-like cell lines expressing
Primitive streak mesoderm-like cell lines expressing

... ectoderm and is down-regulated during differentiation in both mesodermal and neuroectodermal lineages (Scholer et al., 1990). Down-regulation in the mesoderm occurs at approximately the time that Brachyury expression is induced on day 6.5. Oct-3/4 is also down-regulated in P19 EC cells by approximat ...
Autoimmunity Nucleic Acid-Sensing TLRs as Modifiers of
Autoimmunity Nucleic Acid-Sensing TLRs as Modifiers of

... Mrl/lpr mice lacking TLR9. On the other hand, they show that TLR7-deficient Mrl/lpr mice have blocks in anti-RNA autoantibody responses and disease severity. In agreement with the importance of TLR7, Berland et al. (28) have found that TLR7deficient mice bearing an anti-RNA BCR knock-in allele are p ...
Length and Amino Acid Composition Complementarity
Length and Amino Acid Composition Complementarity

... and determining their potential to associate with SLC and be expressed on the cell surface, we were able to determine which specific variable region structures, differing only at the CDR3, render an HC successful. These studies have revealed two characteristics common to successful HCs using VH81X a ...
An FGF4-FRS2[alpha]-Cdx2 Axis in Trophoblast Stem Cells Induces
An FGF4-FRS2[alpha]-Cdx2 Axis in Trophoblast Stem Cells Induces

... Although TS cells self-renew in vitro in the presence of FGF4, which is produced by the ICM in vivo [2, 3], they differentiate into various trophoblastic subtypes in the absence of FGF4. It is thus hypothesized that FGF4 provides a niche for TS cells in embryos [4]. The polar TE, but not the mural T ...
Gastrointestinal Stromal Tumours(GIST)
Gastrointestinal Stromal Tumours(GIST)

Computational cancer biology
Computational cancer biology

Identification of novel MYO18A interaction partners - HAL
Identification of novel MYO18A interaction partners - HAL

... is only a limited number of studies reporting their involvement in myofiber organization and myoblast differentiation11,12, making this broad field quite open for further exploration. Myosin18A, also known as MYO18A/MysPDZ, is the only unconventional myosin containing a PDZ domain in its amino-termi ...
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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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