Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo
... secreted by live tumor cells and/or subcellular secreted compartments, such as exosomes, could represent a source of tumor antigens for the activation of tumor-specific T cells. To test this hypothesis, we have analyzed the immune response induced in vivo by tumors secreting an antigen either specif ...
... secreted by live tumor cells and/or subcellular secreted compartments, such as exosomes, could represent a source of tumor antigens for the activation of tumor-specific T cells. To test this hypothesis, we have analyzed the immune response induced in vivo by tumors secreting an antigen either specif ...
Observations upon the Growing Points in Normal and
... The association of the smaller redox-active granules with the cross-walls of Bacillus megaterium,and their absence from the non-septate filaments produced by growth in the presence of urethane is in accordance with the view that these are growing-points concerned with the development of the cross-wa ...
... The association of the smaller redox-active granules with the cross-walls of Bacillus megaterium,and their absence from the non-septate filaments produced by growth in the presence of urethane is in accordance with the view that these are growing-points concerned with the development of the cross-wa ...
Fulltext PDF - Indian Academy of Sciences
... Characterization of the ppGpp0 strain showed it to filament upon nutritional down shift, suggesting a role for (p)ppGpp in the process of cell division (Xiao et al. 1991). Insights of its role in cell division came from the studies carried out in the D’Ari lab to understand the function of PBP2 (pen ...
... Characterization of the ppGpp0 strain showed it to filament upon nutritional down shift, suggesting a role for (p)ppGpp in the process of cell division (Xiao et al. 1991). Insights of its role in cell division came from the studies carried out in the D’Ari lab to understand the function of PBP2 (pen ...
Plant cell expansion: scaling the wall Fr´ed´eric Nicol and Herman H
... cells such as trichomes and root hairs ([17] and personal communication). RSW1, therefore, seems to be required for primary wall synthesis in all cells. It is not clear to what extent secondary wall formation is affected as well. Shifting the temperature from 18˚C to 31˚C causes the disappearance of ...
... cells such as trichomes and root hairs ([17] and personal communication). RSW1, therefore, seems to be required for primary wall synthesis in all cells. It is not clear to what extent secondary wall formation is affected as well. Shifting the temperature from 18˚C to 31˚C causes the disappearance of ...
An antibody raised to a maize auxin-binding protein has inhibitory
... (Zm-ERabpl), a protein located in the endoplasmic reticulum. A set of evidence indicates that plasma membrane located abpl or abpl-related molecules are involved in the regulation by auxin of ionic exchanges and electrical properties of the plasma membrane in different systems (Barbier-Brygoo et a/. ...
... (Zm-ERabpl), a protein located in the endoplasmic reticulum. A set of evidence indicates that plasma membrane located abpl or abpl-related molecules are involved in the regulation by auxin of ionic exchanges and electrical properties of the plasma membrane in different systems (Barbier-Brygoo et a/. ...
Intracellular distribution of histone mRNAs in human fibroblasts studied
... for poly(A)+ mRNA (Table 1). The distribution of actin mRNA was also evaluated in WI-38 cells and compared to the distribution of histone mRNA and poly(A)+ mRNA. Representative cells are shown in Figs. 5 and 6. Although actin mRNA was broadly distributed throughout the cytoplasm of most cells, it wa ...
... for poly(A)+ mRNA (Table 1). The distribution of actin mRNA was also evaluated in WI-38 cells and compared to the distribution of histone mRNA and poly(A)+ mRNA. Representative cells are shown in Figs. 5 and 6. Although actin mRNA was broadly distributed throughout the cytoplasm of most cells, it wa ...
cell cycle pp
... They may make their own growth factor They may convey a growth factor’s signal without the presence of the growth factor ...
... They may make their own growth factor They may convey a growth factor’s signal without the presence of the growth factor ...
AtLSG1-2 Regulates Leaf Growth by Affecting Cell Proliferation and
... deficiency suppresses endoreduplication. Real-time PCR analysis showed that genes specifically expressed in the proliferation stage were highly expressed and those involved in endoreduplication were differentially regulated. LSG1 is known to mediate the recruitment of nucleocytoplasmic shuttling pro ...
... deficiency suppresses endoreduplication. Real-time PCR analysis showed that genes specifically expressed in the proliferation stage were highly expressed and those involved in endoreduplication were differentially regulated. LSG1 is known to mediate the recruitment of nucleocytoplasmic shuttling pro ...
Caenorhabditis elegans lin-3
... carries a G-to-A transition in the first nucleotide of exon 8 of lin-3 and is predicted to mutate an arginine to a lysine at amino acid 347 of LIN-3 (Figure 1B). The n4951 mutant carries a G-to-A transition that results in a nonsense mutation predicted to truncate LIN-3 after only 26 amino acids, be ...
... carries a G-to-A transition in the first nucleotide of exon 8 of lin-3 and is predicted to mutate an arginine to a lysine at amino acid 347 of LIN-3 (Figure 1B). The n4951 mutant carries a G-to-A transition that results in a nonsense mutation predicted to truncate LIN-3 after only 26 amino acids, be ...
Skb5, an SH3 adaptor protein, regulates Pmk1 MAPK signaling by
... yeast, we established a genetic screen. This screen was based on previous findings from our laboratory (Takada et al., 2007) and others (Carnero et al., 2000) showing that the overexpression of Pck2 in wild-type (WT) cells results in severe growth defects, whereas the inhibition or deletion of the c ...
... yeast, we established a genetic screen. This screen was based on previous findings from our laboratory (Takada et al., 2007) and others (Carnero et al., 2000) showing that the overexpression of Pck2 in wild-type (WT) cells results in severe growth defects, whereas the inhibition or deletion of the c ...
Cajal bodies and coilin—moving towards function
... Simple diffusion appears to be the predominant mechanism when CBs move (Platani et al., 2002). However, CB movement is heterogeneous, differing both among the CB population in a nucleus and for a single CB over time. Many CBs appear restricted in their movement, suggesting some form of tethering to ...
... Simple diffusion appears to be the predominant mechanism when CBs move (Platani et al., 2002). However, CB movement is heterogeneous, differing both among the CB population in a nucleus and for a single CB over time. Many CBs appear restricted in their movement, suggesting some form of tethering to ...
signaling events regulating removal of apoptotic cells
... to have an overlapping tissue distribution in the mouse (Gumienny et al., 2001). However, in situ studies of ELMO1 and ELMO2 in the mouse brain suggest these proteins play cell-type-specific roles (Katoh et al., 2006a). The regulation of ELMO-Dock180 activation appears surprisingly complex. Prelimin ...
... to have an overlapping tissue distribution in the mouse (Gumienny et al., 2001). However, in situ studies of ELMO1 and ELMO2 in the mouse brain suggest these proteins play cell-type-specific roles (Katoh et al., 2006a). The regulation of ELMO-Dock180 activation appears surprisingly complex. Prelimin ...
Cell division and leaf morphogenesis - Development
... Significant progress has been made in our understanding of the plant cell cycle (reviewed by Huntley and Murray, 1999; Mironov et al., 1999). One conclusion from this work has been that although the plant cell cycle shows many similarities with that found in other eukaryotes, differences are also ap ...
... Significant progress has been made in our understanding of the plant cell cycle (reviewed by Huntley and Murray, 1999; Mironov et al., 1999). One conclusion from this work has been that although the plant cell cycle shows many similarities with that found in other eukaryotes, differences are also ap ...
Stress Protein-Binding Polytope Peptides T Cell Responses by DNA
... cell epitopes were presented; Fig. 2, compare C with B). Hence, priming Ld-restricted CD8⫹ T cells seems to down-regulate priming of CD8⫹ T cells to other epitopes of the construct, apparently regardless of their restriction or the nature of the epitope. We immunized F1 (B6 ⫻ BALB/c) mice (Fig. 2D) ...
... cell epitopes were presented; Fig. 2, compare C with B). Hence, priming Ld-restricted CD8⫹ T cells seems to down-regulate priming of CD8⫹ T cells to other epitopes of the construct, apparently regardless of their restriction or the nature of the epitope. We immunized F1 (B6 ⫻ BALB/c) mice (Fig. 2D) ...
Chapter 8: Cellular Transport and the Cell Cycle
... an increased amount of cytoplasm requires increased supplies of enzymes? In many large cells, such as the giant amoeba Pelomyxa shown in Figure 8.8, more than one nucleus is present. Large amounts of DNA in many nuclei ensure that cell activities are carried out quickly and efficiently. ...
... an increased amount of cytoplasm requires increased supplies of enzymes? In many large cells, such as the giant amoeba Pelomyxa shown in Figure 8.8, more than one nucleus is present. Large amounts of DNA in many nuclei ensure that cell activities are carried out quickly and efficiently. ...
Le Van Kim and Wassim El Nemer Grandis, Yves - Labex GR-Ex
... (5, 12, 13). Whereas LW/ICAM-4 is an erythroid-specific protein, Lu/BCAM exhibits a broad expression pattern (14, 15). Lu/BCAM is expressed on resting endothelial cells where it contributes to abnormal SS reticulocyte adhesion by interacting with erythroid integrin ␣41 (16). Hydroxycarbamide (HC, t ...
... (5, 12, 13). Whereas LW/ICAM-4 is an erythroid-specific protein, Lu/BCAM exhibits a broad expression pattern (14, 15). Lu/BCAM is expressed on resting endothelial cells where it contributes to abnormal SS reticulocyte adhesion by interacting with erythroid integrin ␣41 (16). Hydroxycarbamide (HC, t ...
Molecular Characterization and Functional Expression of the Human
... AYjunctions are specialized regions of adjoining cell membranes composed of numerous intercellular low resistance channels. By permitting the passage of ions and chemical mediators from cell to cell, these channels may play a major role in a wide variety of cellular processes, including embryogenesi ...
... AYjunctions are specialized regions of adjoining cell membranes composed of numerous intercellular low resistance channels. By permitting the passage of ions and chemical mediators from cell to cell, these channels may play a major role in a wide variety of cellular processes, including embryogenesi ...