Live-cell mass profiling: an emerging approach in
... and typically show a trend of increasing growth rate with increasing cell mass22,26, suggesting the existence of a mechanism to regulate cell mass during the cell cycle. The high precision of these measurements provides statistically meaningful comparisons between different models of cell growth (fo ...
... and typically show a trend of increasing growth rate with increasing cell mass22,26, suggesting the existence of a mechanism to regulate cell mass during the cell cycle. The high precision of these measurements provides statistically meaningful comparisons between different models of cell growth (fo ...
- Wiley Online Library
... invasion in between CNC streams or induces an early arrest of migration (Theveneau et al., 2010). Sdf1/Cxcr4 axis functions primarily by increasing Rac1 activity, a small Rho GTPase required for lamellipodia formation, and stabilizing cell protrusions, which generate directional movement toward the ...
... invasion in between CNC streams or induces an early arrest of migration (Theveneau et al., 2010). Sdf1/Cxcr4 axis functions primarily by increasing Rac1 activity, a small Rho GTPase required for lamellipodia formation, and stabilizing cell protrusions, which generate directional movement toward the ...
Patients Cell Development Reminiscent to SCID IL
... lthough the importance of TCR-MHC and CD4/CD8MHC interactions in T cell development is well established (1), the role of other molecules in this process is poorly understood. Cytokines have been presumed to play an important role during T cell development, but thus far formal proof has been missing. ...
... lthough the importance of TCR-MHC and CD4/CD8MHC interactions in T cell development is well established (1), the role of other molecules in this process is poorly understood. Cytokines have been presumed to play an important role during T cell development, but thus far formal proof has been missing. ...
Coordination of Cell Cycle Progression and Mitotic
... in synchronised cells revealed a requirement for Set1 for proper cell cycle dependent gene expression and Δset1 cells displayed delayed entry into S phase. Disruption of G1/S regulation in Δmbp1 and Δswi4 transcription factor mutants duplicated both benomyl resistance and suppression of ipl1-2 as wa ...
... in synchronised cells revealed a requirement for Set1 for proper cell cycle dependent gene expression and Δset1 cells displayed delayed entry into S phase. Disruption of G1/S regulation in Δmbp1 and Δswi4 transcription factor mutants duplicated both benomyl resistance and suppression of ipl1-2 as wa ...
Coordinate expression of matrix-degrading proteinases and their
... Studies of extracellular matrix catabolism in other organs provide biochemical tools for determination of MMP activity and gene expression. We used currently available approaches to undertake a comprehensive evaluation of the MMP system of bovine skeletal muscle, including the participating proteina ...
... Studies of extracellular matrix catabolism in other organs provide biochemical tools for determination of MMP activity and gene expression. We used currently available approaches to undertake a comprehensive evaluation of the MMP system of bovine skeletal muscle, including the participating proteina ...
MyoD as a gatekeeper to cell cycle progression
... a phosphorylation mutant of MyoD, the authors observed MyoD loses its affinity for P/CAF upon phosphorylation and instead prefers binding to histone deacetylase 1 (HDAC1), a negative regulator of gene expression. Loss of MyoD phosphorylation resulted in delayed entrance into mitosis. The authors pro ...
... a phosphorylation mutant of MyoD, the authors observed MyoD loses its affinity for P/CAF upon phosphorylation and instead prefers binding to histone deacetylase 1 (HDAC1), a negative regulator of gene expression. Loss of MyoD phosphorylation resulted in delayed entrance into mitosis. The authors pro ...
Hereditary/familial versus sporadic prostate cancer: few indisputable
... found in the African-American populations. A variant of exon 1 – valine (val) to leucine (leu) replacement at codon 89 – confers to val-val homozygous individuals, mainly represented in African-American populations, an increased PC susceptibility risk, whereas the genotype leu-leu, ...
... found in the African-American populations. A variant of exon 1 – valine (val) to leucine (leu) replacement at codon 89 – confers to val-val homozygous individuals, mainly represented in African-American populations, an increased PC susceptibility risk, whereas the genotype leu-leu, ...
Precise control of plant stem cell activity through parallel regulatory
... are described as QC cells; in wild type there are on average two cells at this position in a median longitudinal section (Fig. 1B,N). At c1, cells are undifferentiated and divide frequently, and as such are described as CSCs (Fig. 1B). The CSCs undergo quasi-synchronous periclinal divisions, such th ...
... are described as QC cells; in wild type there are on average two cells at this position in a median longitudinal section (Fig. 1B,N). At c1, cells are undifferentiated and divide frequently, and as such are described as CSCs (Fig. 1B). The CSCs undergo quasi-synchronous periclinal divisions, such th ...
The Aromatic-L-Amino Acid Decarboxylase Inhibitor Carbidopa Is
... The carcinoid tumor is the most frequently occurring neoplasm in the small bowel (1). Surgical resection is usually curative for primary small bowel lesions ⬍2 cm, whereas larger primaries generally metastasize to the liver and are usually lethal. Furthermore, metastatic lesions in the liver are oft ...
... The carcinoid tumor is the most frequently occurring neoplasm in the small bowel (1). Surgical resection is usually curative for primary small bowel lesions ⬍2 cm, whereas larger primaries generally metastasize to the liver and are usually lethal. Furthermore, metastatic lesions in the liver are oft ...
An Adaptive Multiple Access Protocol for Broadcast Channels
... Omnidirectional antennas Directional antennas It is difficult to design such antennas, and most of the time, an antennas covers an area of 60 degrees or 120 degrees Cells served by them are called sectored cells Different sizes of sectored cells are shown in Fig. 5.13 ...
... Omnidirectional antennas Directional antennas It is difficult to design such antennas, and most of the time, an antennas covers an area of 60 degrees or 120 degrees Cells served by them are called sectored cells Different sizes of sectored cells are shown in Fig. 5.13 ...
Gene Section KSR1 (kinase suppressor of ras 1)
... KSR1 is primarily recognized as a scaffold for the Raf/MEK/ERK kinase cascade. However, there are several published studies that sustain that KSR1 has catalytic activity. KSR1 is recognized as a pseudokinase, since mammalian KSR1 does not possess the lysine responsible for ATP orientation and hydrol ...
... KSR1 is primarily recognized as a scaffold for the Raf/MEK/ERK kinase cascade. However, there are several published studies that sustain that KSR1 has catalytic activity. KSR1 is recognized as a pseudokinase, since mammalian KSR1 does not possess the lysine responsible for ATP orientation and hydrol ...
mechanotransduction in lymphatic endothelial cells
... found alone or in association with amorphous elastin in elastic fibers (9). Anchoring filaments merge with perivascular elastic fibers and, more in general, with the vast elastic network of connective tissue (10). Anchoring filaments of initial lymphatic vessels can be assumed to be identical to mic ...
... found alone or in association with amorphous elastin in elastic fibers (9). Anchoring filaments merge with perivascular elastic fibers and, more in general, with the vast elastic network of connective tissue (10). Anchoring filaments of initial lymphatic vessels can be assumed to be identical to mic ...
Rap1b in Smooth Muscle and Endothelium Is Required for
... leads to several cardiovascular defects, including impaired adhesion of blood cells and defective angiogenesis. We found that Rap1b−/− mice develop cardiac hypertrophy and hypertension. Therefore, we examined the function of Rap1b in regulation of blood pressure. Approach and Results—Rap1b−/− mice d ...
... leads to several cardiovascular defects, including impaired adhesion of blood cells and defective angiogenesis. We found that Rap1b−/− mice develop cardiac hypertrophy and hypertension. Therefore, we examined the function of Rap1b in regulation of blood pressure. Approach and Results—Rap1b−/− mice d ...
Untitled - University of Guelph
... Figure 1. Responses in growth and development of diffusely (a–c) and tip-growing (d) cells to disturbances in their microtubule (middle column) and actin (right column) cytoskeletons. Pharmaceutical experiments using microtubule-depolymerizing herbicides such as oryzalin and the microtubule-stabiliz ...
... Figure 1. Responses in growth and development of diffusely (a–c) and tip-growing (d) cells to disturbances in their microtubule (middle column) and actin (right column) cytoskeletons. Pharmaceutical experiments using microtubule-depolymerizing herbicides such as oryzalin and the microtubule-stabiliz ...
the cortical rotation, the wnt pathway
... 4) Glypicans/dally are heparan sulphate proteoglycans (HSPG) with a core protein and long chains of sulphated sugars. The cell surface is covered in HSPGs that act as an “extracellular fly paper” that concentrates ligands at the cell surface. Glypicans are HSPGs attached to the external cell membran ...
... 4) Glypicans/dally are heparan sulphate proteoglycans (HSPG) with a core protein and long chains of sulphated sugars. The cell surface is covered in HSPGs that act as an “extracellular fly paper” that concentrates ligands at the cell surface. Glypicans are HSPGs attached to the external cell membran ...
The src
... Compare c-Src with conserved Src proteins Src contains three domains that are shared with other proteins ...
... Compare c-Src with conserved Src proteins Src contains three domains that are shared with other proteins ...
2/6/12 Bacterial Growth
... • Mechanisms for combating low water activity in surrounding environment involve increasing the internal solute concentration by – Pumping inorganic ions from environment into cell – Synthesis or concentration of organic solutes • compatible solutes: compounds used by cell to counteract low water ac ...
... • Mechanisms for combating low water activity in surrounding environment involve increasing the internal solute concentration by – Pumping inorganic ions from environment into cell – Synthesis or concentration of organic solutes • compatible solutes: compounds used by cell to counteract low water ac ...
The inverse association of cancer and Alzheimer`s
... increases exponentially with age. In view of the age-dependence of these diseases and the dramatic increase in life expectancy during the last 25 years, there has been a tremendous increase in the number of individuals affected with both diseases. Cancer and AD represent increasingly common patholog ...
... increases exponentially with age. In view of the age-dependence of these diseases and the dramatic increase in life expectancy during the last 25 years, there has been a tremendous increase in the number of individuals affected with both diseases. Cancer and AD represent increasingly common patholog ...
Analysis of p75NTR-dependent apoptotic
... apoptosis is associated with an increase in Rac and Jun kinase (JNK) activity, and recent work from our laboratory has shown that the p75NTR interactor, NRAGE, activates a mitochondrial death pathway involving JNK-dependent cytochrome C release and activation of Caspase-9, Caspase-7 and Caspase-3. D ...
... apoptosis is associated with an increase in Rac and Jun kinase (JNK) activity, and recent work from our laboratory has shown that the p75NTR interactor, NRAGE, activates a mitochondrial death pathway involving JNK-dependent cytochrome C release and activation of Caspase-9, Caspase-7 and Caspase-3. D ...
Exosome-Depleted FBS Using Beckman Coulter Centrifugation:
... Beckman Coulter Life Sciences, Indianapolis, IN 46268 Exosomes are small microvesicles, derived from the late endosome, most often described in the literature to be less than 120 nm, released by all cell types, and proven to be involved in cancer metastasis1-3. Exosome characterization and analysis ...
... Beckman Coulter Life Sciences, Indianapolis, IN 46268 Exosomes are small microvesicles, derived from the late endosome, most often described in the literature to be less than 120 nm, released by all cell types, and proven to be involved in cancer metastasis1-3. Exosome characterization and analysis ...
Optimization of Ammonium Sulfate Concentration for Purification of
... in many developing countries where health systems are not well equipped (Rigano and Walmsley, 2005). For use in plant molecular biofarming, the tobacco plant has several advantages over other plants, such as highly efficient transformation and regeneration, relatively short period for biomass producti ...
... in many developing countries where health systems are not well equipped (Rigano and Walmsley, 2005). For use in plant molecular biofarming, the tobacco plant has several advantages over other plants, such as highly efficient transformation and regeneration, relatively short period for biomass producti ...