Volume 7, (2002) pp 1137 – 1151 http://www.cmbl.org.pl Received
... ectopic lignin deposition [22]. The AtCTL1 gene was isolated and its constitutive expression was shown to suppress the elp1 phenotype [23]. The AtCTL1 gene encodes a protein with a structure similar to that of chitinases and is not induced by stress. This may suggest that, in contrast to many known ...
... ectopic lignin deposition [22]. The AtCTL1 gene was isolated and its constitutive expression was shown to suppress the elp1 phenotype [23]. The AtCTL1 gene encodes a protein with a structure similar to that of chitinases and is not induced by stress. This may suggest that, in contrast to many known ...
The nuclear membrane in multidrug resistance
... was produced by prolonged low-dose exposure of MGH-U1 to doxorubicin [20] and MGH-U1-MMC by prolonged low-dose exposure of MGH-U1 to mitomycin C [21]. The inhibitory concentration required to reduce the viable biomass by half of that in controls for each of these cell lines, calculated from tetrazol ...
... was produced by prolonged low-dose exposure of MGH-U1 to doxorubicin [20] and MGH-U1-MMC by prolonged low-dose exposure of MGH-U1 to mitomycin C [21]. The inhibitory concentration required to reduce the viable biomass by half of that in controls for each of these cell lines, calculated from tetrazol ...
Receptor-like Protein-tyrosine Phosphatase Enhances Cell Surface
... highly expressed in the brain, and it affects many aspects of neural development and function, such as neurite outgrowth, neuronal differentiation and migration, ion channel activity, oligodendrocyte differentiation and myelination, hippocampal long term potentiation, and spatial memory (2, 6, 8, 9, ...
... highly expressed in the brain, and it affects many aspects of neural development and function, such as neurite outgrowth, neuronal differentiation and migration, ion channel activity, oligodendrocyte differentiation and myelination, hippocampal long term potentiation, and spatial memory (2, 6, 8, 9, ...
Cell Wall Amine Oxidases: New Players in Root Xylem
... (Spm). Additionally, thermospermine (T-Spm), an isomer of Spm, which has not as yet been detected in mammalian cells, has been found to be widely distributed throughout the plant kingdom [14,15]. Put and Spd are essential for life, as Arabidopsis mutants defective in their biosynthetic pathways are ...
... (Spm). Additionally, thermospermine (T-Spm), an isomer of Spm, which has not as yet been detected in mammalian cells, has been found to be widely distributed throughout the plant kingdom [14,15]. Put and Spd are essential for life, as Arabidopsis mutants defective in their biosynthetic pathways are ...
Characterisation of dendritic cell subsets in lung cancer micro-environments A. Bergeron*
... Indeed, a critical characteristic of fully mature DCs is the production of pro-inflammatory cytokines, particularly IL-12, which plays a critical role in the induction of an efficient Thelper cell 1 immune response, including antitumour cytotoxic immunity [3, 9]. The micro-environment in which DCs a ...
... Indeed, a critical characteristic of fully mature DCs is the production of pro-inflammatory cytokines, particularly IL-12, which plays a critical role in the induction of an efficient Thelper cell 1 immune response, including antitumour cytotoxic immunity [3, 9]. The micro-environment in which DCs a ...
Lenti-X™ Tet-On® Advanced Expression System User
... The Lenti-X Tet-On Advanced Inducible Expression System uses a highly efficient, lentiviral-based gene transfer technology to deliver our tightly regulated and highly responsive Tet-On Advanced Gene expression system into dividing and nondividing target cells, primary cells, and stem cells. While ba ...
... The Lenti-X Tet-On Advanced Inducible Expression System uses a highly efficient, lentiviral-based gene transfer technology to deliver our tightly regulated and highly responsive Tet-On Advanced Gene expression system into dividing and nondividing target cells, primary cells, and stem cells. While ba ...
The Extracellular Matrix
... **Review: A Aszodi, KR Legate, I Nakchbandi, and R. Fassler: What mouse mutants teach us about extracellular matrix function. Annu. Rev. Cell Dev. Biol. 22:591-621, 2006. **Review: JF Bateman, RP Boot-Handford, SR Lamandé: Genetic diseases of connective tissues: cellular and extracellular effets of ...
... **Review: A Aszodi, KR Legate, I Nakchbandi, and R. Fassler: What mouse mutants teach us about extracellular matrix function. Annu. Rev. Cell Dev. Biol. 22:591-621, 2006. **Review: JF Bateman, RP Boot-Handford, SR Lamandé: Genetic diseases of connective tissues: cellular and extracellular effets of ...
When Cells Tell Their Neighbors Which Direction to Divide
... only four other apparent wingless-related genes (cwn-1, cwn-2, lin-44, and egl-20; C. elegans Sequencing Consortium, 1998; Herman et al., 1995; Maloof et al., 1999; Shackleford et al., 1993); whether any of these signal for spindle orientation, or play a redundant role with mom-2, have yet to be tes ...
... only four other apparent wingless-related genes (cwn-1, cwn-2, lin-44, and egl-20; C. elegans Sequencing Consortium, 1998; Herman et al., 1995; Maloof et al., 1999; Shackleford et al., 1993); whether any of these signal for spindle orientation, or play a redundant role with mom-2, have yet to be tes ...
Inhibition of Hepatitis C Virus Genotype 1a Non
... MTT cell proliferation assay was used to evaluate the cytotoxic effects of siRNAs in Huh-7 cells by using Lipofectamine™ 2000 (Invitrogen, USA) as transfection reagent in a dose-dependent manner. Huh-7 cells at a density of 2 × 103 cells/well were cultured in 96-well tissue culture plate. After 24 h ...
... MTT cell proliferation assay was used to evaluate the cytotoxic effects of siRNAs in Huh-7 cells by using Lipofectamine™ 2000 (Invitrogen, USA) as transfection reagent in a dose-dependent manner. Huh-7 cells at a density of 2 × 103 cells/well were cultured in 96-well tissue culture plate. After 24 h ...
Guidleine on potency testing of cell based immunotherapy medicinal
... Appropriately designed potency assays provide an accurate, reliable and consistent demonstration of the biological activity of the active ingredient either at the level of drug substance and/or drug product. In principle the results of a potency assay should provide assurance that the amount of the ...
... Appropriately designed potency assays provide an accurate, reliable and consistent demonstration of the biological activity of the active ingredient either at the level of drug substance and/or drug product. In principle the results of a potency assay should provide assurance that the amount of the ...
growth polarity and cytokinesis in fission yeast: the role of the
... F-actin. T hese findings, which were originally established in wild-type cells (Marks & Hyam s, 1985), have been confirmed here by the use of cell division cycle mutants arrested at different points of the cell cycle by growth at the restrictive temperature (N urse et al. 1976). In cdc 10 both actin ...
... F-actin. T hese findings, which were originally established in wild-type cells (Marks & Hyam s, 1985), have been confirmed here by the use of cell division cycle mutants arrested at different points of the cell cycle by growth at the restrictive temperature (N urse et al. 1976). In cdc 10 both actin ...
Skin and bones: the bacterial cytoskeleton, cell wall, and cell
... is borne out by physical modeling, and C. crescentus vibrioid cells, which elongate into helices after an extended time in stationary phase, obey one of the predictions of the model, namely that helical pitch will decrease as cells elongate (Wolgemuth et al., 2005). An alternative hypothesis derives ...
... is borne out by physical modeling, and C. crescentus vibrioid cells, which elongate into helices after an extended time in stationary phase, obey one of the predictions of the model, namely that helical pitch will decrease as cells elongate (Wolgemuth et al., 2005). An alternative hypothesis derives ...
Cell cycle and differentiation
... into a transit amplifying meristemoid cell might be controlled directly by the potential to replicate and/or to proceed into a G2-like state; this is an example in which cell-cycle decisions appear to precede differentiation (Figure 2a). Another link between cell-division control and the formation o ...
... into a transit amplifying meristemoid cell might be controlled directly by the potential to replicate and/or to proceed into a G2-like state; this is an example in which cell-cycle decisions appear to precede differentiation (Figure 2a). Another link between cell-division control and the formation o ...
Making inroads into plant receptor kinase signalling pathways
... these receptors requires heterodimerization and transphosphorylation [6]. There are no data available for the integral CLV1 receptor but a kinase-active form of the cytosolic domain of CLV1 does transphosphorylate a kinase-inactive form of the same domain in vitro [44]. Taken together, these observa ...
... these receptors requires heterodimerization and transphosphorylation [6]. There are no data available for the integral CLV1 receptor but a kinase-active form of the cytosolic domain of CLV1 does transphosphorylate a kinase-inactive form of the same domain in vitro [44]. Taken together, these observa ...
A Deficiency in Drak2 Results in a T Cell
... apoptosis promoted by the DAP-like family of kinases. Members of this family include DAP kinase, DRP-1, ZIP kinase, DRAK1, and DRAK2 (Kogel et al., 2001). These serine/threonine kinases share homology within their N-terminal kinase domains but vary extensively in their C-terminal domains. All member ...
... apoptosis promoted by the DAP-like family of kinases. Members of this family include DAP kinase, DRP-1, ZIP kinase, DRAK1, and DRAK2 (Kogel et al., 2001). These serine/threonine kinases share homology within their N-terminal kinase domains but vary extensively in their C-terminal domains. All member ...
Prentice Hall Biology
... The cell cycle is regulated by a specific protein. The amount of this protein in the cell rises and falls in time with the cell cycle. Scientists called this protein cyclin because it seemed to regulate the cell cycle. Cyclins regulate the timing of the cell cycle in eukaryotic cells. ...
... The cell cycle is regulated by a specific protein. The amount of this protein in the cell rises and falls in time with the cell cycle. Scientists called this protein cyclin because it seemed to regulate the cell cycle. Cyclins regulate the timing of the cell cycle in eukaryotic cells. ...
Cytoskeletal control of plant cell shape: getting the fine points
... As katanins have been shown to function as microtubulesevering proteins [8], work on AtKTN1 implicates microtubule severing as an important mechanism for achieving the proper organization of microtubules in expanding cells. The Arabidopsis MICROTUBULE ORGANIZATION1 (MOR1) gene encodes a protein that ...
... As katanins have been shown to function as microtubulesevering proteins [8], work on AtKTN1 implicates microtubule severing as an important mechanism for achieving the proper organization of microtubules in expanding cells. The Arabidopsis MICROTUBULE ORGANIZATION1 (MOR1) gene encodes a protein that ...
Phosphorylation of initiation factor2 is required for
... of mRNAs is poorly translated due to the extraordinarily long, structured, upstream AUG-burdened 5¢UTRs that serve as barriers for ribosomal scanning. Interestingly, such translational inhibitors often belong to mRNAs encoding proteins involved in cell growth and differentiation such as growth facto ...
... of mRNAs is poorly translated due to the extraordinarily long, structured, upstream AUG-burdened 5¢UTRs that serve as barriers for ribosomal scanning. Interestingly, such translational inhibitors often belong to mRNAs encoding proteins involved in cell growth and differentiation such as growth facto ...
Mutations in SIPA1L3 cause eye defects through disruption of cell
... These disorders cause a lifetime of visual disability and there is marked genetic heterogeneity with many of the pathogenic mechanisms not yet fully identified or understood (4) and no specific therapies are currently available. Genes where mutations are known to cause lens and eye developmental disor ...
... These disorders cause a lifetime of visual disability and there is marked genetic heterogeneity with many of the pathogenic mechanisms not yet fully identified or understood (4) and no specific therapies are currently available. Genes where mutations are known to cause lens and eye developmental disor ...
Immunocytochemical Localization of the
... various forms of leukemias and lymphomas (1,2). These actions may be both direct on the malignant cell and indirect, through the down-regulation of lymphokines upon which some, but not all such malignancies depend (3). The exact cause of the direct lympholytic action of glucocorticoids is unknown; i ...
... various forms of leukemias and lymphomas (1,2). These actions may be both direct on the malignant cell and indirect, through the down-regulation of lymphokines upon which some, but not all such malignancies depend (3). The exact cause of the direct lympholytic action of glucocorticoids is unknown; i ...
Summary and Conclusion Facultyof Pharmacy Department of
... the most common cause for end stage renal disease. Adenosine is an endogenous purine nucleoside released from various tissues and organs. Adenosine controls the supply and demand of energy and modulates a variety of physiological responses by interacting with specific cell surface G-protein-coupled ...
... the most common cause for end stage renal disease. Adenosine is an endogenous purine nucleoside released from various tissues and organs. Adenosine controls the supply and demand of energy and modulates a variety of physiological responses by interacting with specific cell surface G-protein-coupled ...