MICROSTRUCTURE OF PROTEIN BODIES IN MARAMA BEAN SPECIES
... of soya may be attributed to the soluble form of its phytic acid. Druse crystals (one per protein body) were observed only in protein bodies from T. esculentum (Fig. 3 D). Druse crystals consist of cluster of small crystals in arrangement called a druse or rosette (Lott, 1981). This type of inclusio ...
... of soya may be attributed to the soluble form of its phytic acid. Druse crystals (one per protein body) were observed only in protein bodies from T. esculentum (Fig. 3 D). Druse crystals consist of cluster of small crystals in arrangement called a druse or rosette (Lott, 1981). This type of inclusio ...
CELL MIGRATION IN THE FOREBRAIN
... Modulation of Radial Movement by Motogenic Factors Brain derived neurotrophic factor (BDNF) and NT4, members of the neurotrophin family, have been shown to promote the migration of cortical neurons. TrkB, the high-affinity receptor of BDNF and NT4, is expressed in migrating neurons in the cortical p ...
... Modulation of Radial Movement by Motogenic Factors Brain derived neurotrophic factor (BDNF) and NT4, members of the neurotrophin family, have been shown to promote the migration of cortical neurons. TrkB, the high-affinity receptor of BDNF and NT4, is expressed in migrating neurons in the cortical p ...
Zinc Neurotoxicity and its Role in Neurodegenerative Diseases
... in the brain, particularly in the hippocampus, amygdala, cerebral cortex, and olfactory cortex. The total amount of zinc in the hippocampus is estimated as 70–90 ppm (dry weight).3) Although some zinc in the brain firmly binds to metalloproteins or enzymes, a substantial amount of zinc (approximatel ...
... in the brain, particularly in the hippocampus, amygdala, cerebral cortex, and olfactory cortex. The total amount of zinc in the hippocampus is estimated as 70–90 ppm (dry weight).3) Although some zinc in the brain firmly binds to metalloproteins or enzymes, a substantial amount of zinc (approximatel ...
Exocytosis Precedes and Predicts the Increase in
... 50 s (Pierson et al., 1996; Cárdenas et al., 2008). Additionally, many of the underlying processes also oscillate with the same period, but usually with a different phase than the growth rate (Holdaway-Clarke and Hepler, 2003; Chebli and Geitmann, 2007; Moreno et al., 2007). Thus, growth emerges as ...
... 50 s (Pierson et al., 1996; Cárdenas et al., 2008). Additionally, many of the underlying processes also oscillate with the same period, but usually with a different phase than the growth rate (Holdaway-Clarke and Hepler, 2003; Chebli and Geitmann, 2007; Moreno et al., 2007). Thus, growth emerges as ...
General introduction - University of Amsterdam
... from a nutrient-rich environment like the body is not necessary (48). Yeasts as model organisms Since ancient times the yeast Saccharomyces cerevisiae has been used for baking and brewing, but in the last century it was recognized as a suitable unicellular model organism to study eukaryotic cells, p ...
... from a nutrient-rich environment like the body is not necessary (48). Yeasts as model organisms Since ancient times the yeast Saccharomyces cerevisiae has been used for baking and brewing, but in the last century it was recognized as a suitable unicellular model organism to study eukaryotic cells, p ...
Distinct Roles of PDE4 and PDE10A in the Regulation of cAMP/PKA
... Phosphodiesterase (PDE) is a critical regulator of cAMP/protein kinase A (PKA) signaling in cells. Multiple PDEs with different substrate specificities and subcellular localization are expressed in neurons. Dopamine plays a central role in the regulation of motor and cognitive functions. The effect ...
... Phosphodiesterase (PDE) is a critical regulator of cAMP/protein kinase A (PKA) signaling in cells. Multiple PDEs with different substrate specificities and subcellular localization are expressed in neurons. Dopamine plays a central role in the regulation of motor and cognitive functions. The effect ...
Purified Hexameric Epstein-Barr Virus-Encoded BARF1 Protein for Measuring Anti-BARF1 Antibody
... The functions assigned to BARF1 are diverse. BARF1 has been shown to have transforming activity and to prevent senescence (33, 44, 45) and apoptosis (3, 42). Secreted BARF1 protein (sBARF1) has been reported to have mitogenic activity on human B cells and primary monkey kidney epithelial cells (30). ...
... The functions assigned to BARF1 are diverse. BARF1 has been shown to have transforming activity and to prevent senescence (33, 44, 45) and apoptosis (3, 42). Secreted BARF1 protein (sBARF1) has been reported to have mitogenic activity on human B cells and primary monkey kidney epithelial cells (30). ...
Reactive oxygen species, abiotic stress and stress combination
... will contact the nuclear envelope and could directly alter the ROS status of the nuclei (Noctor and Foyer, 2016). However, if labile Fe2+ exist in cells, ROS such as H2O2 can react with it to generate the highly toxic hydroxyl radical that would lead to oxidative stress and cell damage. Regulating i ...
... will contact the nuclear envelope and could directly alter the ROS status of the nuclei (Noctor and Foyer, 2016). However, if labile Fe2+ exist in cells, ROS such as H2O2 can react with it to generate the highly toxic hydroxyl radical that would lead to oxidative stress and cell damage. Regulating i ...
Molecular Genetic Analysis of Phototropism in
... function by mediating light-dependent redox reactions. Crys also mainly localize in the nucleus (Fig. 2), and control the expression of a number of genes under blue light conditions (reviewed by Jiao et al. 2007). Genetic studies have indicated that phys and crys function positively in phototropism. ...
... function by mediating light-dependent redox reactions. Crys also mainly localize in the nucleus (Fig. 2), and control the expression of a number of genes under blue light conditions (reviewed by Jiao et al. 2007). Genetic studies have indicated that phys and crys function positively in phototropism. ...
Gene Section FST (follistatin) Atlas of Genetics and Cytogenetics
... bound activin is unable to initiate signal transduction and consequently follistatin is a potent antagonist of physiological activin signals. Of the three follistatin domains present in all follistatin isoforms, (Shimasaki et al., 1988) the first two, but not the third, are necessary for activin A b ...
... bound activin is unable to initiate signal transduction and consequently follistatin is a potent antagonist of physiological activin signals. Of the three follistatin domains present in all follistatin isoforms, (Shimasaki et al., 1988) the first two, but not the third, are necessary for activin A b ...
Mitochondria - Physical Mathematics
... bacteria, simpler versions of essentially the same protein complexes produce ATP, but they are located in the cell’s plasma membrane (Figure 14–1). Comparisons of DNA sequences indicate that the energy-converting organelles in present-day eukaryotes originated from prokaryotic cells that were endocy ...
... bacteria, simpler versions of essentially the same protein complexes produce ATP, but they are located in the cell’s plasma membrane (Figure 14–1). Comparisons of DNA sequences indicate that the energy-converting organelles in present-day eukaryotes originated from prokaryotic cells that were endocy ...
- Wiley Online Library
... Fig 1 | Cellular stress induces p53-dependent responses. In response to cellular stress such as DNA damage, the p53 protein becomes stabilized. In the nucleus, p53 binds to specific promoters and activates transcription of its target genes. Additionally, p53 can also repress transcription of some of ...
... Fig 1 | Cellular stress induces p53-dependent responses. In response to cellular stress such as DNA damage, the p53 protein becomes stabilized. In the nucleus, p53 binds to specific promoters and activates transcription of its target genes. Additionally, p53 can also repress transcription of some of ...
Pericentriolar material structure and dynamics
... The resolution required to distinguish subdomains within the PCM would not be achieved until the implementation of EM tomography. Using this approach, in combination with immunolabelling, Moritz et al. [3] could discern gamma-tubulin-containing ring structures 25–30 nm in diameter within PCM from is ...
... The resolution required to distinguish subdomains within the PCM would not be achieved until the implementation of EM tomography. Using this approach, in combination with immunolabelling, Moritz et al. [3] could discern gamma-tubulin-containing ring structures 25–30 nm in diameter within PCM from is ...
Abundant Type III Lipid Transfer Proteins in
... anthers of Arabidopsis are abundant in the tapetum (see “Results”). Why the tapetum needs such a high amount of LTPs to carry out the proposed catalytic function of transferring lipids is an intriguing question. In individual plant species, LTPs are encoded by several dozen paralogs. They are catego ...
... anthers of Arabidopsis are abundant in the tapetum (see “Results”). Why the tapetum needs such a high amount of LTPs to carry out the proposed catalytic function of transferring lipids is an intriguing question. In individual plant species, LTPs are encoded by several dozen paralogs. They are catego ...
Substrate Specificity and Mechanism from the Structure of
... acting as the ligand sensor and transducer of galactose signal.12 Sequence analysis has shown that there is a very high similarity (73% identity) between the yeast proteins Gal1p and Gal3p.13 However, despite this similarity, Gal3p does not show galactokinase activity and the transcriptional activat ...
... acting as the ligand sensor and transducer of galactose signal.12 Sequence analysis has shown that there is a very high similarity (73% identity) between the yeast proteins Gal1p and Gal3p.13 However, despite this similarity, Gal3p does not show galactokinase activity and the transcriptional activat ...
Single-Amino Acid Substitutions Alter the Specificity and Affinity of
... A second type of PDZ domain interaction is not dependent upon recognition of a carboxy-terminal motif (2). A wellcharacterized example is the binding of the PDZ domain of neuronal nitric oxide synthase (nNOS) to the second PDZ domain of PSD-95 or to the PDZ domain of R1-syntrophin (11). The former c ...
... A second type of PDZ domain interaction is not dependent upon recognition of a carboxy-terminal motif (2). A wellcharacterized example is the binding of the PDZ domain of neuronal nitric oxide synthase (nNOS) to the second PDZ domain of PSD-95 or to the PDZ domain of R1-syntrophin (11). The former c ...
Actin machinery: pushing the envelope Gary G Borisy* and Tatyana
... the tail is mediated by N-WASP, which binds IcsA, F-actin and the Arp2/3 complex, and which may function like VASP to keep barbed ends close to the bacterial surface [27••]. In cells, VASP family proteins may play a role similar to that proposed for Listeria, as they have been found at the tips of f ...
... the tail is mediated by N-WASP, which binds IcsA, F-actin and the Arp2/3 complex, and which may function like VASP to keep barbed ends close to the bacterial surface [27••]. In cells, VASP family proteins may play a role similar to that proposed for Listeria, as they have been found at the tips of f ...
Regulation of chromatin by histone modifications
... stable, static modification. Nevertheless, in 2002, a number of different reactions/pathways were suggested as potential demethylation mechanisms for both lysine and arginine [28], which were subsequently verified experimentally. Initially, the conversion of arginine to citrulline via a deimination ...
... stable, static modification. Nevertheless, in 2002, a number of different reactions/pathways were suggested as potential demethylation mechanisms for both lysine and arginine [28], which were subsequently verified experimentally. Initially, the conversion of arginine to citrulline via a deimination ...
Correlating ribosome function with high
... Figure 1. The ribosome functional centers. (a) The two ribosomal subunits. Left: the small ribosomal subunit (T30S) [4]. The approximate positions of codon–anticodon interactions of A-, P- and E-tRNAs are shown and the main functional domains are indicated: H, head; L, latch; P, platform; S, shoulde ...
... Figure 1. The ribosome functional centers. (a) The two ribosomal subunits. Left: the small ribosomal subunit (T30S) [4]. The approximate positions of codon–anticodon interactions of A-, P- and E-tRNAs are shown and the main functional domains are indicated: H, head; L, latch; P, platform; S, shoulde ...
PDF - Potter Lab
... cells, endoreplication does not occur. We further performed flow cytometry analysis on Tsc1 mutant cells from wing discs following the technique introduced by Edgar and colleagues (Neufeld et al., 1998). We found that Tsc1 mutant cells exhibited normal DNA contents despite an increase in cell size t ...
... cells, endoreplication does not occur. We further performed flow cytometry analysis on Tsc1 mutant cells from wing discs following the technique introduced by Edgar and colleagues (Neufeld et al., 1998). We found that Tsc1 mutant cells exhibited normal DNA contents despite an increase in cell size t ...
PDF
... proteins were selected because they contain sDMA residues in their C-terminal tails. No accumulation of GFP-SmD1 could be detected at the posterior pole of the oocyte of transgenic females (Fig. 2A), but a significant amount of GFP-SmD3 was detected at this location (Fig. 2B). To check whether the l ...
... proteins were selected because they contain sDMA residues in their C-terminal tails. No accumulation of GFP-SmD1 could be detected at the posterior pole of the oocyte of transgenic females (Fig. 2A), but a significant amount of GFP-SmD3 was detected at this location (Fig. 2B). To check whether the l ...
RNA-binding proteins and RNA metabolism: a new scenario in the
... differences and similarities TDP-43 and FUS/TLS are DNA/RNA binding proteins which are both structurally related to the heterogeneous ribonucleoproteins (hnRNPs) family, a group of predominantly nuclear RBPs with different cellular functions that form molecular complexes binding heterogeneous nuclea ...
... differences and similarities TDP-43 and FUS/TLS are DNA/RNA binding proteins which are both structurally related to the heterogeneous ribonucleoproteins (hnRNPs) family, a group of predominantly nuclear RBPs with different cellular functions that form molecular complexes binding heterogeneous nuclea ...
Molecular and functional anatomy of the mouse olfactory epithelium
... domains 4 and 5, and to a lesser extent transmembrane domain 3, are ...
... domains 4 and 5, and to a lesser extent transmembrane domain 3, are ...
Raven Ch
... Ca2+ channels open. Ca2+ causes synaptic vesicles to fuse with the axon membrane at the synapse. Synaptic vesicles release their neurotransmitter. Neurotransmitter molecules diffuse across synaptic cleft. Postsynaptic receptor proteins bind neurotransmitter. Postsynaptic membrane depolarizes. If thi ...
... Ca2+ channels open. Ca2+ causes synaptic vesicles to fuse with the axon membrane at the synapse. Synaptic vesicles release their neurotransmitter. Neurotransmitter molecules diffuse across synaptic cleft. Postsynaptic receptor proteins bind neurotransmitter. Postsynaptic membrane depolarizes. If thi ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.