PDF - Geoff McFadden`s Lab
... pathways for fatty acids and isoprenoids (FIG. 4). Dark plastids also require energy and reducing power, which they usually obtain by importing glucose for use in a plastid-localized glycolytic pathway. No evidence has been found to indicate that the apicoplast can import or process hexoses, so its ...
... pathways for fatty acids and isoprenoids (FIG. 4). Dark plastids also require energy and reducing power, which they usually obtain by importing glucose for use in a plastid-localized glycolytic pathway. No evidence has been found to indicate that the apicoplast can import or process hexoses, so its ...
![[Ca2+]c dynamics in spontaneously firing dopamine neurons of the](http://s1.studyres.com/store/data/003492398_1-2708bc56966b4cab721b0073b5bc49ec-300x300.png)
[Ca2+]c dynamics in spontaneously firing dopamine neurons of the
... metabolism (Duchen, 1999), gene expression (Gallin and Greenberg, 1995; Ginty, 1997), and neurotoxicity (Sattler and Tymianski, 2000). Since glutamate is involved in many such functions and can activate various glutamate receptors, the [Ca2+]c signals related to glutamate receptors in neuronal cells ...
... metabolism (Duchen, 1999), gene expression (Gallin and Greenberg, 1995; Ginty, 1997), and neurotoxicity (Sattler and Tymianski, 2000). Since glutamate is involved in many such functions and can activate various glutamate receptors, the [Ca2+]c signals related to glutamate receptors in neuronal cells ...
Carbohydrate Biosensors
... Magnification of enzymatic signals has been achieved through multiple glycoenzyme layering.5 Such lectinbased immobilization methods have opened the way to assemblies with higher glycoenzyme affinities and better load factors. Varied synthetic developments have focused on identification of solid mat ...
... Magnification of enzymatic signals has been achieved through multiple glycoenzyme layering.5 Such lectinbased immobilization methods have opened the way to assemblies with higher glycoenzyme affinities and better load factors. Varied synthetic developments have focused on identification of solid mat ...
Role of Sodium Channel Deglycosylation in the Genesis of Cardiac
... To investigate the arrhythmogenic potential of the prolonged APs in MLP"/" animals, myocytes were stimulated at 1 Hz for periods of 1 min. Clusters of 5 APs from WT and MLP"/" records are shown in Fig. 1C. Arrhythmogenic voltage fluctuations called early afterdepolarization (EADs, Fig. 1C) were freq ...
... To investigate the arrhythmogenic potential of the prolonged APs in MLP"/" animals, myocytes were stimulated at 1 Hz for periods of 1 min. Clusters of 5 APs from WT and MLP"/" records are shown in Fig. 1C. Arrhythmogenic voltage fluctuations called early afterdepolarization (EADs, Fig. 1C) were freq ...
Left–right asymmetry: cilia stir up new surprises in the node
... Cilia are microtubule-based hair-like organelles that project from the surface of most eukaryotic cells. They play critical roles in cellular motility, fluid transport and a variety of signal transduction pathways. While we have a good appreciation of the mechanisms of ciliary biogenesis and the det ...
... Cilia are microtubule-based hair-like organelles that project from the surface of most eukaryotic cells. They play critical roles in cellular motility, fluid transport and a variety of signal transduction pathways. While we have a good appreciation of the mechanisms of ciliary biogenesis and the det ...
REVIEWS
... cascades in the chick embryo. A cascade of sidespecific transcripts that has been characterized in the chick is shown, and is overlaid on the dorsal view of a Hamburger Hamilton stage 5 chick embryo (anterior to the top). Sonic hedgehog (SHH) is expressed on both sides of Hensen’s node until the chi ...
... cascades in the chick embryo. A cascade of sidespecific transcripts that has been characterized in the chick is shown, and is overlaid on the dorsal view of a Hamburger Hamilton stage 5 chick embryo (anterior to the top). Sonic hedgehog (SHH) is expressed on both sides of Hensen’s node until the chi ...
ATP regulation in bioproduction
... The enhanced yields of ATP generated by the overexpression of enzymes that catalyze ATP biosynthesis are critical for increasing the ATP supply and the yields of target compounds (Fig. 2). Deletion of the gene encoding non-ATP-generating acetic acid synthetic aldehyde dehydrogenase of Caldicellulosi ...
... The enhanced yields of ATP generated by the overexpression of enzymes that catalyze ATP biosynthesis are critical for increasing the ATP supply and the yields of target compounds (Fig. 2). Deletion of the gene encoding non-ATP-generating acetic acid synthetic aldehyde dehydrogenase of Caldicellulosi ...
ATP regulation in bioproduction
... The enhanced yields of ATP generated by the overexpression of enzymes that catalyze ATP biosynthesis are critical for increasing the ATP supply and the yields of target compounds (Fig. 2). Deletion of the gene encoding non-ATP-generating acetic acid synthetic aldehyde dehydrogenase of Caldicellulosi ...
... The enhanced yields of ATP generated by the overexpression of enzymes that catalyze ATP biosynthesis are critical for increasing the ATP supply and the yields of target compounds (Fig. 2). Deletion of the gene encoding non-ATP-generating acetic acid synthetic aldehyde dehydrogenase of Caldicellulosi ...
Identification of Saccharomyces cerevisiae proteins that bind to
... solenoid model in that alternate nucleosomes interact with each other and sequential nucleosomes (nucleosomes connected by linker DNA) are positioned opposite each other. This way the linker DNA can remain more rigid and a secondary structure resembling a “two start” helix is formed (Dorigo et al. 2 ...
... solenoid model in that alternate nucleosomes interact with each other and sequential nucleosomes (nucleosomes connected by linker DNA) are positioned opposite each other. This way the linker DNA can remain more rigid and a secondary structure resembling a “two start” helix is formed (Dorigo et al. 2 ...
mTORC1 and the regulation of skeletal muscle anabolism and mass
... alone or in combination with intake of protein or amino acids. Because increased activity of the complex is implicated in the development of muscle insulin resistance, obesity, and some cancers (e.g., ovarian, breast), drugs that target mTORC1 are being developed or are in clinical trials. However, ...
... alone or in combination with intake of protein or amino acids. Because increased activity of the complex is implicated in the development of muscle insulin resistance, obesity, and some cancers (e.g., ovarian, breast), drugs that target mTORC1 are being developed or are in clinical trials. However, ...
Immunocytochemical Distribution of the
... monkeys, intense CB1 immunoreactivity was observed primarily in axons and boutons. Across neocortical regions of the monkey brain, CB1-immunoreactive (IR) axons exhibited considerable heterogeneity in density and laminar distribution. Neocortical association regions, such as the prefrontal and cingu ...
... monkeys, intense CB1 immunoreactivity was observed primarily in axons and boutons. Across neocortical regions of the monkey brain, CB1-immunoreactive (IR) axons exhibited considerable heterogeneity in density and laminar distribution. Neocortical association regions, such as the prefrontal and cingu ...
Glia-Derived D-Serine Controls NMDA Receptor Activity and
... There is strong evidence for reciprocal communication between neurons and glia (Fields and Stevens-Graham, 2002; Haydon, 2001; Volterra and Meldolesi, 2005). Astrocytes detect changes in the activity of their adjacent neurons through ion channels, receptors, and transporters expressed on their surfa ...
... There is strong evidence for reciprocal communication between neurons and glia (Fields and Stevens-Graham, 2002; Haydon, 2001; Volterra and Meldolesi, 2005). Astrocytes detect changes in the activity of their adjacent neurons through ion channels, receptors, and transporters expressed on their surfa ...
Intestinal peptidases form functional complexes with the neutral
... amino acid [3]. The active site of APN defines its specificity for N-terminal amino acid residues. All aminopeptidase family members belong to the gluzincin metalloprotease family, with two consensus zinc-binding sequences, HEXXH and BXLXE (zincbinding residues are indicated in bold, B indicates a b ...
... amino acid [3]. The active site of APN defines its specificity for N-terminal amino acid residues. All aminopeptidase family members belong to the gluzincin metalloprotease family, with two consensus zinc-binding sequences, HEXXH and BXLXE (zincbinding residues are indicated in bold, B indicates a b ...
Glyphosate pathways to modern diseases V: Amino
... Glyphosate, a synthetic amino acid and analogue of glycine, is the most widely used biocide on the planet. Its presence in food for human consumption and animal feed is ubiquitous. Epidemiological studies have revealed a strong correlation between the increasing incidence in the United States of a l ...
... Glyphosate, a synthetic amino acid and analogue of glycine, is the most widely used biocide on the planet. Its presence in food for human consumption and animal feed is ubiquitous. Epidemiological studies have revealed a strong correlation between the increasing incidence in the United States of a l ...
Modulation of functional properties of bifunctional S- Adenosylmethionine decarboxylase/Ornithine decarboxylase of
... Trishydroxy (methyl-amino) methane / Hydrochloric acid ...
... Trishydroxy (methyl-amino) methane / Hydrochloric acid ...
calculating the structure-based phylogenetic relationship
... This work is dedicated to my mother, father, and brother; they helped when I required it most. ...
... This work is dedicated to my mother, father, and brother; they helped when I required it most. ...
Student notes in ppt
... androgens, which is how females acquire testosterone for estradiol production. The chemical and molecular structure of steroid hormones, as well as, the structure of the steroid hormone binding domain of a steroid receptor protein, are shown below. Note the similar structure to cholesterol and the h ...
... androgens, which is how females acquire testosterone for estradiol production. The chemical and molecular structure of steroid hormones, as well as, the structure of the steroid hormone binding domain of a steroid receptor protein, are shown below. Note the similar structure to cholesterol and the h ...
Activation of ryanodine receptors induces calcium influx in a
... in the 401L cell line, thapsigargin treatment fails to induce Ca2+ influx, in contrast with most cell types tested for this response [7]. Moreover, it has been shown that these cells fail to produce a small molecule CIF (calcium influx factor) activity when treated with thapsigargin, unlike T lympho ...
... in the 401L cell line, thapsigargin treatment fails to induce Ca2+ influx, in contrast with most cell types tested for this response [7]. Moreover, it has been shown that these cells fail to produce a small molecule CIF (calcium influx factor) activity when treated with thapsigargin, unlike T lympho ...
Interactions of Elongation Factor 1 Cell Protrusions with F-Actin and
... sorting of -actin protein to this region. -Actin has been suggested to be an important player in leading edge dynamics by virtue of its isoform-specific interaction with other proteins (such as ezrin and -Cap73; Shuster et al., 1996). The sorting of -actin mRNA requires transport and then select ...
... sorting of -actin protein to this region. -Actin has been suggested to be an important player in leading edge dynamics by virtue of its isoform-specific interaction with other proteins (such as ezrin and -Cap73; Shuster et al., 1996). The sorting of -actin mRNA requires transport and then select ...
Disruption of morphogenesis and transformation of
... evidence suggests that the KN1 protein itself could be the signal that moves from the corpus to cells of the tunica layer (Jackson et al., 1994). The nature of interactions between different parts of the early embryo are less well understood. Polar auxin transport is thought to be required for the t ...
... evidence suggests that the KN1 protein itself could be the signal that moves from the corpus to cells of the tunica layer (Jackson et al., 1994). The nature of interactions between different parts of the early embryo are less well understood. Polar auxin transport is thought to be required for the t ...
The Formation of Terminal Fields in the Absence of Competitive
... junctions almost exclusively on appropriate muscle fibers, rather than by overproduction and selective elimination of inappropriate branches. Retraction of the few branches that are inappropriately placed, though correlated in time with the ingrowth of branches from appropriate motoneurons, occurs i ...
... junctions almost exclusively on appropriate muscle fibers, rather than by overproduction and selective elimination of inappropriate branches. Retraction of the few branches that are inappropriately placed, though correlated in time with the ingrowth of branches from appropriate motoneurons, occurs i ...
Role of branched-chain amino acid transporters in Staphylococcus
... pigmentation of the colonies is caused by carotenoids, whose biosynthetic pathway has recently been determined (107). Moreover, the carotenoids have been shown to act as virulence factors, due to their ability to protect the pathogen from oxidants produced by the immune system (79). Staphylococci ha ...
... pigmentation of the colonies is caused by carotenoids, whose biosynthetic pathway has recently been determined (107). Moreover, the carotenoids have been shown to act as virulence factors, due to their ability to protect the pathogen from oxidants produced by the immune system (79). Staphylococci ha ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.