ABSTRACT Title of Document:
... Figure 2. Domain organization of BarA ....................................................................24 Figure 3. Domain organization of UvrY....................................................................27 Figure 4. Schematic representation of the BarA/UvrY/Csr System .................... ...
... Figure 2. Domain organization of BarA ....................................................................24 Figure 3. Domain organization of UvrY....................................................................27 Figure 4. Schematic representation of the BarA/UvrY/Csr System .................... ...
Hormonal interactions during root tropic growth: hydrotropism versus
... Cholodny–Went theory proposes that auxin plays a key role in several tropisms. Recent molecular genetic studies have strongly supported this hypothesis for gravitropism. However, the molecular mechanisms of other tropisms are far less clear. Hydrotropism is the response of roots to a moisture gradie ...
... Cholodny–Went theory proposes that auxin plays a key role in several tropisms. Recent molecular genetic studies have strongly supported this hypothesis for gravitropism. However, the molecular mechanisms of other tropisms are far less clear. Hydrotropism is the response of roots to a moisture gradie ...
Reverse migration of neutrophils: Where, when, how and why
... phenomena of neutrophil migration away from the foci of inflammation have been extensively studied in the zebrafish [44]. The first such studies were conducted by Anna Huttenlocher and colleagues using a zebrafish embryo tailfin injury model [13]. Zebrafish inflammation models are perhaps the simple ...
... phenomena of neutrophil migration away from the foci of inflammation have been extensively studied in the zebrafish [44]. The first such studies were conducted by Anna Huttenlocher and colleagues using a zebrafish embryo tailfin injury model [13]. Zebrafish inflammation models are perhaps the simple ...
BACILLUS SPHAERICUS TOXINS: Molecular Biology and Mode of
... three repeated regions ~90amino acids each, the function of which is unknown; the 27-kDa fragment contains a short region corresponding to a transmembrane domain. The 27-kDa part of Mtx1 shares weak similarity with the catalytic domain of several ADP-ribosylating toxins (76, 77). Mtx2 has 34 and 29% ...
... three repeated regions ~90amino acids each, the function of which is unknown; the 27-kDa fragment contains a short region corresponding to a transmembrane domain. The 27-kDa part of Mtx1 shares weak similarity with the catalytic domain of several ADP-ribosylating toxins (76, 77). Mtx2 has 34 and 29% ...
RESULTATS Capítol 1 __________________________________________________________________________ 71
... A large number of extracellular diffusible and membrane-bound molecules, as well as extracellular matrix proteins, play a central role in the guidance and development of neural connections (Huber et al., 2003; Mueller, 1999). In some cases, such as Netrin-1, the same signal participates in both neur ...
... A large number of extracellular diffusible and membrane-bound molecules, as well as extracellular matrix proteins, play a central role in the guidance and development of neural connections (Huber et al., 2003; Mueller, 1999). In some cases, such as Netrin-1, the same signal participates in both neur ...
LEFT-HANDED Z-DNA: STRUCTURE AND FUNCTION
... show that, at low concentrations of antibody, the amount of Z-DNA measured was independent of the antibody added over a 100-fold change in antibody concentration, suggesting that the Z-DNA is present de novo in these preparations rather than being induced by antibody. Furthermore, the amount of Z-DN ...
... show that, at low concentrations of antibody, the amount of Z-DNA measured was independent of the antibody added over a 100-fold change in antibody concentration, suggesting that the Z-DNA is present de novo in these preparations rather than being induced by antibody. Furthermore, the amount of Z-DN ...
Inhibitory Regulation of Higher-Plant Myosin by
... was not reversible upon Ca21 removal. An 18-kD polypeptide that showed the same mobility in sodium dodecyl sulfate-polyacrylamide gel electrophoresis as that of spinach calmodulin (CaM) was present in this myosin fraction. This polypeptide showed a mobility shift in sodium dodecyl sulfate-polyacryla ...
... was not reversible upon Ca21 removal. An 18-kD polypeptide that showed the same mobility in sodium dodecyl sulfate-polyacrylamide gel electrophoresis as that of spinach calmodulin (CaM) was present in this myosin fraction. This polypeptide showed a mobility shift in sodium dodecyl sulfate-polyacryla ...
Polycystin-1 maturation requires polycystin-2 in a dose
... Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited nephropathy responsible for 4%–10% of endstage renal disease cases. Mutations in the genes encoding polycystin-1 (PC1, PKD1) or polycystin-2 (PC2, PKD2) cause ADPKD, and PKD1 mutations are associated with more severe renal di ...
... Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited nephropathy responsible for 4%–10% of endstage renal disease cases. Mutations in the genes encoding polycystin-1 (PC1, PKD1) or polycystin-2 (PC2, PKD2) cause ADPKD, and PKD1 mutations are associated with more severe renal di ...
Growing models of vertebrate limb development - ICB-USP
... exposed to high morphogen concentrations and form posterior digits, whereas cells further away, exposed to increasingly lower concentrations, form progressively more anterior digits (Tickle et al., 1975; Wolpert, 1969). Saunders and Gasseling discovered the polarizing region or zone of polarizing ac ...
... exposed to high morphogen concentrations and form posterior digits, whereas cells further away, exposed to increasingly lower concentrations, form progressively more anterior digits (Tickle et al., 1975; Wolpert, 1969). Saunders and Gasseling discovered the polarizing region or zone of polarizing ac ...
Multiomics of tomato glandular trichomes reveals
... chromatograms of LA1777 (Supplemental Figure 2). These results confirm previous metabolite analyses of tomato trichomes and underline that trichomes of these species produce different terpenoid secondary metabolites (Slocombe et al., 2008; Besser et al., 2009; Schilmiller et al., 2010; McDowell e ...
... chromatograms of LA1777 (Supplemental Figure 2). These results confirm previous metabolite analyses of tomato trichomes and underline that trichomes of these species produce different terpenoid secondary metabolites (Slocombe et al., 2008; Besser et al., 2009; Schilmiller et al., 2010; McDowell e ...
Sequence Variability Analysis of Human Class I and Class II MHC
... HLA-B and HLA-C. Only the a chains of these mature HLA class I molecules are encoded within the class I HLA locus by the respective HLA-A, HLA-B and HLA-C genes. In contrast, the b2m chain encoded by the b2m gene is located on chromosome 15. The classical HLA class II molecules are also of three typ ...
... HLA-B and HLA-C. Only the a chains of these mature HLA class I molecules are encoded within the class I HLA locus by the respective HLA-A, HLA-B and HLA-C genes. In contrast, the b2m chain encoded by the b2m gene is located on chromosome 15. The classical HLA class II molecules are also of three typ ...
Salmonella pathogenicity island 1 (SPI-1) type III
... sufficient to mediate secretion through its cognate T3SS, requiring a secondary NSS identified as the chaperonebinding domain (CBD). The CBD is located within the first ~140 amino acids of some secreted proteins and harbours the binding site for the cognate chaperone, which is generally required for ...
... sufficient to mediate secretion through its cognate T3SS, requiring a secondary NSS identified as the chaperonebinding domain (CBD). The CBD is located within the first ~140 amino acids of some secreted proteins and harbours the binding site for the cognate chaperone, which is generally required for ...
Prospero regulates gcm expression to induce glial fates
... Recent work has identified several proteins that may be involved in these processes. The Inscuteable (Insc) protein is apically localized in mitotic neuroblasts, where it is required for the apical-basal orientation of the spindle; indeed, misexpression of Insc in epithelial cells that normally divi ...
... Recent work has identified several proteins that may be involved in these processes. The Inscuteable (Insc) protein is apically localized in mitotic neuroblasts, where it is required for the apical-basal orientation of the spindle; indeed, misexpression of Insc in epithelial cells that normally divi ...
- CUNY Academic Works
... (VTA) and projects to forebrain regions such as the nucleus accumbens (NAcc), amygdala (AMG) and prefrontal cortex (PFC). These forebrain regions will be referred to as the DA terminal regions. The neural mechanisms underlying this type of rewardrelated learning in this system are not fully understo ...
... (VTA) and projects to forebrain regions such as the nucleus accumbens (NAcc), amygdala (AMG) and prefrontal cortex (PFC). These forebrain regions will be referred to as the DA terminal regions. The neural mechanisms underlying this type of rewardrelated learning in this system are not fully understo ...
... Constitutive Cycling of Golgi Proteins in and out of Golgi Bodies Our ability to stop the directional movement of Golgi structures by latrunculin B treatment allowed us to investigate the extent of protein cycling of ST-GFP and AtERD2-GFP in and out of Golgi bodies using photobleaching recovery tech ...
Specific features of glycogen metabolism in the liver
... the ‘ muscle ’, ‘ brain ’ and ‘ liver ’ isoenzymes according to the tissue in which they are preferentially expressed (reviewed in [33,34]). They are homodimers of subunits of E 100 kDa and are encoded by different genes. All isoenzymes are converted from the inactive b-form into the active a form t ...
... the ‘ muscle ’, ‘ brain ’ and ‘ liver ’ isoenzymes according to the tissue in which they are preferentially expressed (reviewed in [33,34]). They are homodimers of subunits of E 100 kDa and are encoded by different genes. All isoenzymes are converted from the inactive b-form into the active a form t ...
NCAM Polypeptides in Heart Development: Association with Z Discs
... lar region and the outflow tract but not in the atrium or ventricle (Markwald et al., 1984). The ECT arises from cells of the endocardial endothelium that deadhere, convert into mesenchymal cells, and migrate into the cardiac jelly (Markwald et al., 1978). Neural cell adhesion molecule (NCAM) is con ...
... lar region and the outflow tract but not in the atrium or ventricle (Markwald et al., 1984). The ECT arises from cells of the endocardial endothelium that deadhere, convert into mesenchymal cells, and migrate into the cardiac jelly (Markwald et al., 1978). Neural cell adhesion molecule (NCAM) is con ...
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... have identified a variety of factors that regulate dendrite branch formation, the molecular mechanisms that control this process remain poorly defined. Here, we introduce the use of the Caenorhabditis elegans PVD neurons, a pair of putative nociceptors that elaborate complex dendritic arbors, as a t ...
... have identified a variety of factors that regulate dendrite branch formation, the molecular mechanisms that control this process remain poorly defined. Here, we introduce the use of the Caenorhabditis elegans PVD neurons, a pair of putative nociceptors that elaborate complex dendritic arbors, as a t ...
The Role of the Terminal Nerve and GnRH in Olfactory System
... Animals receive important information about their environment via their sensory organs, enabling organisms to respond appropriately to external cues. The olfactory system plays an important role in translating environmental chemical information into electrical signals that can be recognized accurate ...
... Animals receive important information about their environment via their sensory organs, enabling organisms to respond appropriately to external cues. The olfactory system plays an important role in translating environmental chemical information into electrical signals that can be recognized accurate ...
and Abscisic Acid Response Elements in the Em Promoter
... VP1 are required for induction of the maize Em homolog during embryo development (McCarty et al., 1991). VPl is also specifically required during seed development for the activation of C7, a regulatory gene of the anthocyanin biosynthetic pathway (McCarty et ai., 1989b; Hattori et al., 1992).Our pre ...
... VP1 are required for induction of the maize Em homolog during embryo development (McCarty et al., 1991). VPl is also specifically required during seed development for the activation of C7, a regulatory gene of the anthocyanin biosynthetic pathway (McCarty et ai., 1989b; Hattori et al., 1992).Our pre ...
Drosophila embryos close epithelial wounds using a combination of
... components including myosin, E-cadherin, Echinoid, the plasma membrane, microtubules, and the Cdc42 small GTPase respond dynamically during wound repair, and demonstrate that perturbations of each of these components result in abnormal wound healing. Our results show that embryo epithelial wound rep ...
... components including myosin, E-cadherin, Echinoid, the plasma membrane, microtubules, and the Cdc42 small GTPase respond dynamically during wound repair, and demonstrate that perturbations of each of these components result in abnormal wound healing. Our results show that embryo epithelial wound rep ...
Theranostic Value of Multimers: Lessons Learned from Trimerization
... as a possible molecular agent for (radio)therapy and/or diagnosis of cancer by targeting NTS1 [6,7]. The shortest binding sequence of NT to NTS1 is the C-terminal fragment NT(8–13) with the amino acids Arg8 -Arg9 -Pro10 -Tyr11 -Ile12 -Leu13 -OH. This peptide sequence is rapidly degraded in vivo with ...
... as a possible molecular agent for (radio)therapy and/or diagnosis of cancer by targeting NTS1 [6,7]. The shortest binding sequence of NT to NTS1 is the C-terminal fragment NT(8–13) with the amino acids Arg8 -Arg9 -Pro10 -Tyr11 -Ile12 -Leu13 -OH. This peptide sequence is rapidly degraded in vivo with ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.