Characterization of a Novel Peripheral Nervous System Myelin
... ledto the hypothesis that PO may be responsible for the adhesion between the extracellular surfaces of the myelin plasma membrane. Recent studies on cultured cells clearly demonstrate the capacity of PO to undergo homophilic interactions (Filbin et al ., 1990; Schneider-Schaulies et al ., 1990; D'Ur ...
... ledto the hypothesis that PO may be responsible for the adhesion between the extracellular surfaces of the myelin plasma membrane. Recent studies on cultured cells clearly demonstrate the capacity of PO to undergo homophilic interactions (Filbin et al ., 1990; Schneider-Schaulies et al ., 1990; D'Ur ...
The interplay between light and jasmonate
... et al., 2010), a commonly used marker gene for the JAregulated wound response. Other JA- and COI1-dependent responses such as wound- or JA-mediated growth reduction of leaves and anthocyanin accumulation patterns were not different in the phyA mutant, suggesting that PHYA is required for only a subs ...
... et al., 2010), a commonly used marker gene for the JAregulated wound response. Other JA- and COI1-dependent responses such as wound- or JA-mediated growth reduction of leaves and anthocyanin accumulation patterns were not different in the phyA mutant, suggesting that PHYA is required for only a subs ...
08_NervousSystem
... • Ions move thru trans-membrane channels • Some membrane channels can open or close. • Some membrane channels are always open (=“leak channels.”) • If Na+ channels open positive charges enter cell membrane potential becomes more (+). (This is called depolarization.) • If K+ channels open posit ...
... • Ions move thru trans-membrane channels • Some membrane channels can open or close. • Some membrane channels are always open (=“leak channels.”) • If Na+ channels open positive charges enter cell membrane potential becomes more (+). (This is called depolarization.) • If K+ channels open posit ...
NG2 glial cells integrate synaptic input in global and dendritic
... additional analysis including all dendrite recordings. We binned trials according to stimulus 8 of 43 ...
... additional analysis including all dendrite recordings. We binned trials according to stimulus 8 of 43 ...
PDF
... have shown that the shape of the particle can have a strong effect on phagocytosis [17]. In another study, the Fc density was varied on a spherical particle to understand the effects on cell signaling and commitment of the macrophage to phagocytosis. This study utilized 5.6 mm polystyrene particles ...
... have shown that the shape of the particle can have a strong effect on phagocytosis [17]. In another study, the Fc density was varied on a spherical particle to understand the effects on cell signaling and commitment of the macrophage to phagocytosis. This study utilized 5.6 mm polystyrene particles ...
Serine/Threonine Kinase 3-Phosphoinositide
... To execute persistent migration, cells establish leading and trailing edges in which different signaling pathways stimulate membrane protrusion and retraction, respectively. In most cases, cell orientation is determined by external gradients of soluble and/or adhesive factors. Even in the absence of ...
... To execute persistent migration, cells establish leading and trailing edges in which different signaling pathways stimulate membrane protrusion and retraction, respectively. In most cases, cell orientation is determined by external gradients of soluble and/or adhesive factors. Even in the absence of ...
Bioinformatic Software in Web
... Modifications of proteins can be determined only by proteomic methodologies. It is necessary to determine the protein expression level. The localization of gene products can be determined experimentally. Protein-protein interactions. Proteins are direct drug targets. ...
... Modifications of proteins can be determined only by proteomic methodologies. It is necessary to determine the protein expression level. The localization of gene products can be determined experimentally. Protein-protein interactions. Proteins are direct drug targets. ...
structure-function analysis of the drosophila stubble type ii
... The catalytic activity of TTSPs is dependent on the presence of three residues in the proteolytic domain, histidine, aspartate, and serine, which make up the catalytic triad. Enzymatic activity is further modulated by the structural organization of the substrate binding pocket which is responsible f ...
... The catalytic activity of TTSPs is dependent on the presence of three residues in the proteolytic domain, histidine, aspartate, and serine, which make up the catalytic triad. Enzymatic activity is further modulated by the structural organization of the substrate binding pocket which is responsible f ...
Chapter 6: Metal induced selectivity in phosphate ion binding in
... Colicin E9 is a member of a family of bacterial endonuclease colicins that are protein antibiotics released by Escherichia coli into the extracellular medium during times of nutrient or environmental stress. On entrance into target cells the 15-kDa C-terminal DNase domain is translocated into the cy ...
... Colicin E9 is a member of a family of bacterial endonuclease colicins that are protein antibiotics released by Escherichia coli into the extracellular medium during times of nutrient or environmental stress. On entrance into target cells the 15-kDa C-terminal DNase domain is translocated into the cy ...
The Amino Acid Sequences of the Myelin
... MAG was isolated by the method of Quarles and Pasnak (39). In brief, purified rat brain myelin (32) was extracted with chloroform/methanol (2:1 vol/vol). The insoluble residue was treated with 0.25 M lithium diiodosalicylate and partitioned with phenol. The aqueous phase, which is enriched in MAG, w ...
... MAG was isolated by the method of Quarles and Pasnak (39). In brief, purified rat brain myelin (32) was extracted with chloroform/methanol (2:1 vol/vol). The insoluble residue was treated with 0.25 M lithium diiodosalicylate and partitioned with phenol. The aqueous phase, which is enriched in MAG, w ...
Vesicle-Mediated Transport and Release of
... Whenever neurons in the CNS are injured, microglia become activated. In addition to local activation, microglia remote from the primary lesion site are stimulated. Because this so-called secondary activation of microglia is instrumental for long-term changes after neuronal injury, it is important to ...
... Whenever neurons in the CNS are injured, microglia become activated. In addition to local activation, microglia remote from the primary lesion site are stimulated. Because this so-called secondary activation of microglia is instrumental for long-term changes after neuronal injury, it is important to ...
CS790 – Introduction to Bioinformatics
... • Protein disulfide isomerase – catalyzes shuffling of disulfide bonds • Chaperones – break up aggregates and (in theory) unfold misfolded proteins ...
... • Protein disulfide isomerase – catalyzes shuffling of disulfide bonds • Chaperones – break up aggregates and (in theory) unfold misfolded proteins ...
Molecular Cloning of CD68, a Human Macrophage
... observed depending on the cDNA clone used (Fig I); pCD68.1 encodes a protein of approximately 1 I O Kd, while CD68.2 encodes a protein of approximately 80 Kd. KPI failed to immunoprecipitate any protein from the transfectants, consistent with the fact that it may recognize macrophagerestricted glyca ...
... observed depending on the cDNA clone used (Fig I); pCD68.1 encodes a protein of approximately 1 I O Kd, while CD68.2 encodes a protein of approximately 80 Kd. KPI failed to immunoprecipitate any protein from the transfectants, consistent with the fact that it may recognize macrophagerestricted glyca ...
Cellular Biology - Circulation Research
... mitochondria. Proteolytic processing of cell-surface receptors, such as epidermal growth factor receptor tyrosine kinase B4, can release intracellular domains that trigger mitochondrial release of proapoptotic proteins.13 Energy deprivation responses, such as AMP kinase activation, induce mitochondr ...
... mitochondria. Proteolytic processing of cell-surface receptors, such as epidermal growth factor receptor tyrosine kinase B4, can release intracellular domains that trigger mitochondrial release of proapoptotic proteins.13 Energy deprivation responses, such as AMP kinase activation, induce mitochondr ...
Neuromodulation of in Layer II Medial Entorhinal Cortex I
... Stellate cells in layer II of medial entorhinal cortex (mEC) are endowed with a large hyperpolarization-activated cation current [h current (Ih )]. Recent work using in vivo recordings from awake behaving rodents demonstrate that Ih plays a significant role in regulating the characteristic spatial p ...
... Stellate cells in layer II of medial entorhinal cortex (mEC) are endowed with a large hyperpolarization-activated cation current [h current (Ih )]. Recent work using in vivo recordings from awake behaving rodents demonstrate that Ih plays a significant role in regulating the characteristic spatial p ...
The Spemann Organizer Signal noggin Binds and
... and 5B1, did not significantly affect noggin activity (Figure 6A). Antibodies alone had no effect on explants. MAb1A4’s effects were specific for Xenopus noggin, since induction of muscle actin by human noggin protein or by injection of mRNAs encoding two alternative dorsalizing agents—chordin and a ...
... and 5B1, did not significantly affect noggin activity (Figure 6A). Antibodies alone had no effect on explants. MAb1A4’s effects were specific for Xenopus noggin, since induction of muscle actin by human noggin protein or by injection of mRNAs encoding two alternative dorsalizing agents—chordin and a ...
Stimulation of growth of the human gastric
... Results: We cultured Hp under a range of O2 levels with or without 10% CO2 and evaluated growth profiles, morphology, intracellular pH, and energy metabolism. We found that, in the presence of 10% CO2, the normal atmospheric level of O2 inhibited Hp growth at low density but stimulated growth at a h ...
... Results: We cultured Hp under a range of O2 levels with or without 10% CO2 and evaluated growth profiles, morphology, intracellular pH, and energy metabolism. We found that, in the presence of 10% CO2, the normal atmospheric level of O2 inhibited Hp growth at low density but stimulated growth at a h ...
Document
... action potential is triggered in the axon, and the information is relayed to the CNS. ...
... action potential is triggered in the axon, and the information is relayed to the CNS. ...
Artk96_CyclGMPReview_2016 - Pure
... All living organisms communicate with their environment and part of this dialogue is mediated by secondary messengers such as cyclic Guanosine Mono Phosphate (cGMP). In plants, most of the specific components that allow production and break-down of cGMP have now been identified apart from cGMP depen ...
... All living organisms communicate with their environment and part of this dialogue is mediated by secondary messengers such as cyclic Guanosine Mono Phosphate (cGMP). In plants, most of the specific components that allow production and break-down of cGMP have now been identified apart from cGMP depen ...
7.2 Glycolysis
... Glycolysis Glycolysis is the first stage of cellular respiration Glycolysis occurs with or without oxygen (during both aerobic and anaerobic respiration) Glycolysis takes place in the cytoplasm of the cell During glycolysis glucose is split in two to form 2 pyruvate molecules ...
... Glycolysis Glycolysis is the first stage of cellular respiration Glycolysis occurs with or without oxygen (during both aerobic and anaerobic respiration) Glycolysis takes place in the cytoplasm of the cell During glycolysis glucose is split in two to form 2 pyruvate molecules ...
cilia regeneration in tetrahymena and its inhibition
... was assessed by scoring the percentage of motile cells at intervals following deciliation. After a 30-min lag, the deciliated cells rapidly recovered motility until more than 90% of the cells were motile at 70 min after amputation. Cycloheximide inhibited both protein synthesis and cilia regeneratio ...
... was assessed by scoring the percentage of motile cells at intervals following deciliation. After a 30-min lag, the deciliated cells rapidly recovered motility until more than 90% of the cells were motile at 70 min after amputation. Cycloheximide inhibited both protein synthesis and cilia regeneratio ...
Transcription factor AP-2 is tissue-specific in
... Subsequently, we identified a protein-binding positiveregulatory sequence within this promoter region, mutation of which reduced epidermal expression of the injected gene by up to 90% (Snape et al. 1990). (We recently learned that in these expression studies we erroneously used as a control DNA a co ...
... Subsequently, we identified a protein-binding positiveregulatory sequence within this promoter region, mutation of which reduced epidermal expression of the injected gene by up to 90% (Snape et al. 1990). (We recently learned that in these expression studies we erroneously used as a control DNA a co ...
Chapter 9 Muscle
... the overlapping thick and thin filaments in each sarcomere move past each other, propelled 推動 by the movements of the cross-bridges ...
... the overlapping thick and thin filaments in each sarcomere move past each other, propelled 推動 by the movements of the cross-bridges ...
A pollen-specific calmodulin-binding protein, NPG1, interacts with
... calmodulin-binding domain (CBD). Genetic studies have shown that AtNPG1 is required for pollen germination but not for pollen development30. The amino acid sequence of AtNPG1 and the maize homolog share 56% identity and 70% similarity. Homologs of NPG1 are also identified in other plants including V ...
... calmodulin-binding domain (CBD). Genetic studies have shown that AtNPG1 is required for pollen germination but not for pollen development30. The amino acid sequence of AtNPG1 and the maize homolog share 56% identity and 70% similarity. Homologs of NPG1 are also identified in other plants including V ...
Chapter 4. Unnatural amino acids with caged side chains
... The advent of techniques to alter the amino acids of proteins has permitted the consideration of ‘caged proteins,’ in which particular residues in a protein are provided with photo-removable protecting groups. A number of recent reviews have presented a survey of this literature.21-23 Interesting ex ...
... The advent of techniques to alter the amino acids of proteins has permitted the consideration of ‘caged proteins,’ in which particular residues in a protein are provided with photo-removable protecting groups. A number of recent reviews have presented a survey of this literature.21-23 Interesting ex ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.