1 Nucleoli: Composition, Function and Dynamics
... interspersed with them, and it is merely an assumption that all rDNA repeats are potentially transcribable. As with other genomic regions, current models suggest that ...
... interspersed with them, and it is merely an assumption that all rDNA repeats are potentially transcribable. As with other genomic regions, current models suggest that ...
Nucleolus-like body of mouse oocytes contains lamin A and B and
... suggested as one of the most universal and evolutionarilyconserved nuclear domains [24, 25]. They primarily represent nuclear storage sites for pre-mRNA splicing factors [3, 26, 27], though extensive studies conducted during the past two decades have introduced the notion that IGC functions are broa ...
... suggested as one of the most universal and evolutionarilyconserved nuclear domains [24, 25]. They primarily represent nuclear storage sites for pre-mRNA splicing factors [3, 26, 27], though extensive studies conducted during the past two decades have introduced the notion that IGC functions are broa ...
T cell metabolism drives immunity
... group identified mice with enhanced CD8 T cell responses to viral and tumor challenge (Okoye et al., 2015). The source of the heightened immunity gained after germline mutagenesis was the increased expression of an orphan protein, identified as lymphocyte expansion molecule (LEM). Interestingly, aug ...
... group identified mice with enhanced CD8 T cell responses to viral and tumor challenge (Okoye et al., 2015). The source of the heightened immunity gained after germline mutagenesis was the increased expression of an orphan protein, identified as lymphocyte expansion molecule (LEM). Interestingly, aug ...
the Cell
... • All cells resemble one another in fundamental ways • However they differ from one another in important aspects • Unicellular organisms must carry out all the necessary functions in one cell • Multicellular organisms have cells which are specialized for particular functions © 2012 Pearson Education ...
... • All cells resemble one another in fundamental ways • However they differ from one another in important aspects • Unicellular organisms must carry out all the necessary functions in one cell • Multicellular organisms have cells which are specialized for particular functions © 2012 Pearson Education ...
Specification of the C. elegans MS blastomere by the T
... tbx-35 is expressed in cells that have MS identity As embryonic activation of tbx-35 is restricted to MS, we assessed association of tbx-35 with ‘MS fate’ by evaluating its expression in mutant backgrounds that generate ectopic MS-like cells. A tbx35::GFP reporter is activated ectopically in the AB ...
... tbx-35 is expressed in cells that have MS identity As embryonic activation of tbx-35 is restricted to MS, we assessed association of tbx-35 with ‘MS fate’ by evaluating its expression in mutant backgrounds that generate ectopic MS-like cells. A tbx35::GFP reporter is activated ectopically in the AB ...
Novel role for the Lu/BCAM–spectrin interaction in actin cytoskeleton
... repeat [15]. As Lu/BCAM represents a minor component of the RBC membrane (from 1.5 to 4 copies/RBC), we have speculated that the Lu/BCAM–spectrin interaction might be critical for cell signalling rather than for maintenance of the membrane mechanical properties [12]. The adhesion properties of Lu/BC ...
... repeat [15]. As Lu/BCAM represents a minor component of the RBC membrane (from 1.5 to 4 copies/RBC), we have speculated that the Lu/BCAM–spectrin interaction might be critical for cell signalling rather than for maintenance of the membrane mechanical properties [12]. The adhesion properties of Lu/BC ...
as a PDF
... Anabolic and catabolic pathways are generally regulated in a reciprocal manner, such that increases in the activity of one are often accompanied by decreases in the other (9). In response to fasting, for example, catabolic pathways are inhibited, while anabolic pathways are activated, thus allowing ...
... Anabolic and catabolic pathways are generally regulated in a reciprocal manner, such that increases in the activity of one are often accompanied by decreases in the other (9). In response to fasting, for example, catabolic pathways are inhibited, while anabolic pathways are activated, thus allowing ...
11/5/2014 Cannabinoids Activate CB Receptors
... Does not have psychoactive properties on its own though antagonizes some effects of THC • Does not have psychoactive properties on its own though antagonizes some effects of THC ‐ antipsychotic ‐ anxiolytic • CB2 inverse agonist, 5‐HT1A agonist, antagonist of putative new CB receptor GRP55 ...
... Does not have psychoactive properties on its own though antagonizes some effects of THC • Does not have psychoactive properties on its own though antagonizes some effects of THC ‐ antipsychotic ‐ anxiolytic • CB2 inverse agonist, 5‐HT1A agonist, antagonist of putative new CB receptor GRP55 ...
Glycogen Metabolism - http://www.utm.edu
... without the accumulation of glucose. It is said that “GP is the glucose sensor”: a) In the phospho (active) form, the P’s on GP are “buried” where PP1 can’t get at them. b) When G binds to active GP-P, its conformation changes, “exposing” the P’s so PP1 can “clip them” off. c) PP1 binds strongly to ...
... without the accumulation of glucose. It is said that “GP is the glucose sensor”: a) In the phospho (active) form, the P’s on GP are “buried” where PP1 can’t get at them. b) When G binds to active GP-P, its conformation changes, “exposing” the P’s so PP1 can “clip them” off. c) PP1 binds strongly to ...
Centrosome Maturation and Mitotic Spindle Assembly in C. elegans
... temperature matured into fertile adults (see Experimental Procedures). We conclude that other genes provide similar functions later in development, or that SPD-5 and centrosomes may be important for bipolar spindle ...
... temperature matured into fertile adults (see Experimental Procedures). We conclude that other genes provide similar functions later in development, or that SPD-5 and centrosomes may be important for bipolar spindle ...
molbiolcell.org
... mothers). Alternatively, its function could be substituted by one of the other members of the Argonaute family. We addressed these questions by first examining which of the Argonaute family members are present in oocytes and preimplantation embryos and then by systematically depleting them in combin ...
... mothers). Alternatively, its function could be substituted by one of the other members of the Argonaute family. We addressed these questions by first examining which of the Argonaute family members are present in oocytes and preimplantation embryos and then by systematically depleting them in combin ...
chapter_14_respiration_in_plants
... Respiration is generally assumed to be a catabolic process because during respiration, various substrates are broken down for deriving energy. Carbohydrates are broken down to glucose before entering respiratory pathways. Fats get converted into fatty acids and glycerol whereas fatty acids get conve ...
... Respiration is generally assumed to be a catabolic process because during respiration, various substrates are broken down for deriving energy. Carbohydrates are broken down to glucose before entering respiratory pathways. Fats get converted into fatty acids and glycerol whereas fatty acids get conve ...
Role of neurons and glia in the CNS actions of the renin
... are present on separate chromosomes but are highly homologous (119, 160). Within the brain of rodents, AT1R is primarily present in its AT1aR form; however, in some cases, AT1bR has been detected in the brain, and it is also abundant in the anterior pituitary and adrenal cortex (27, 95, 105). In rod ...
... are present on separate chromosomes but are highly homologous (119, 160). Within the brain of rodents, AT1R is primarily present in its AT1aR form; however, in some cases, AT1bR has been detected in the brain, and it is also abundant in the anterior pituitary and adrenal cortex (27, 95, 105). In rod ...
Я-Amyloid-Induced Synthesis of the Ganglioside Gd3 Is a Requisite
... and nuclear chromatin (red) showed few neurons expressing GD3 in control cultures or in cultures exposed to the reverse peptide AP(35–25). Nearly all neurons became immunopositive for GD3 in neurons exposed to AP(25–35). Immunoreactivity was mostly detected in cell nuclei ( yellow) after the addit ...
... and nuclear chromatin (red) showed few neurons expressing GD3 in control cultures or in cultures exposed to the reverse peptide AP(35–25). Nearly all neurons became immunopositive for GD3 in neurons exposed to AP(25–35). Immunoreactivity was mostly detected in cell nuclei ( yellow) after the addit ...
ARTÍCULOS
... At this point, IPTG (isopropyl--D-galactopyranoside) was added to 0.5 mM, and incubation was carried out for 15 min. Cells were then pelleted by centrifugation and resuspended in 20 ml of buffer A (20 mM HEPES [pH 7.9], 10% glycerol, 100 mM KCl, 5 mM MgCl2, 50 mM imidazole). Clear cellular extracts ...
... At this point, IPTG (isopropyl--D-galactopyranoside) was added to 0.5 mM, and incubation was carried out for 15 min. Cells were then pelleted by centrifugation and resuspended in 20 ml of buffer A (20 mM HEPES [pH 7.9], 10% glycerol, 100 mM KCl, 5 mM MgCl2, 50 mM imidazole). Clear cellular extracts ...
fulltext - DiVA Portal
... Membranes are composed of a largely apolar lipid matrix densely punctuated with a large number of different proteins. These so-called membrane proteins usually span the lipid matrix and protrude out into the space on either side of the membrane. Over millions of years of evolution, cells have develo ...
... Membranes are composed of a largely apolar lipid matrix densely punctuated with a large number of different proteins. These so-called membrane proteins usually span the lipid matrix and protrude out into the space on either side of the membrane. Over millions of years of evolution, cells have develo ...
Bacterial Growth and Cell Division: a Mycobacterial Perspective
... L-alanyl-D-iso-glutaminyl-meso-DAP-D-alanine from a different strand. While all bacteria require a dibasic residue for cross-linking PG, there are several residues from which to choose. Most gram-positive bacteria utilize lysine; however, DAP is commonly used instead by actinomycetes and gramnegativ ...
... L-alanyl-D-iso-glutaminyl-meso-DAP-D-alanine from a different strand. While all bacteria require a dibasic residue for cross-linking PG, there are several residues from which to choose. Most gram-positive bacteria utilize lysine; however, DAP is commonly used instead by actinomycetes and gramnegativ ...
Quantitative Host Cell Protein Analysis Using Two
... content provided by ELISA analysis is currently acceptable for lot-release, it does not provide any information on the profile or properties of HCPs present which may be used for process design improvement. Hence methods that facilitate identification of individual HCPs have gained prominence in recen ...
... content provided by ELISA analysis is currently acceptable for lot-release, it does not provide any information on the profile or properties of HCPs present which may be used for process design improvement. Hence methods that facilitate identification of individual HCPs have gained prominence in recen ...
Development of angiosperm seed is a complex process
... PA biosynthesis in the endothelium, regulates the biosynthesis of mucilage during seed coat epidermal differentiation. GL3 and EGL are bHLH transcription factors that act redundantly to promote mucilage biosynthesis and interact with TTG1 [36,37]. Thus GL3 and EGL replace TT8 as the TTG1 complex bHL ...
... PA biosynthesis in the endothelium, regulates the biosynthesis of mucilage during seed coat epidermal differentiation. GL3 and EGL are bHLH transcription factors that act redundantly to promote mucilage biosynthesis and interact with TTG1 [36,37]. Thus GL3 and EGL replace TT8 as the TTG1 complex bHL ...
fulltekst
... SR proteins ..........................................................................................21 SR-related proteins ..............................................................................24 Phosphorylation and dephosphorylation of SR proteins......................24 Proteins regulati ...
... SR proteins ..........................................................................................21 SR-related proteins ..............................................................................24 Phosphorylation and dephosphorylation of SR proteins......................24 Proteins regulati ...
The Spatial Pattern of Cochlear Amplification
... hair cells. This frequency-dependent wave profile is brought about by an interplay between longitudinal fluid coupling and local displacement of the cochlear partition, whose stiffness and mass are graded (Lighthill, 1981). In a normal ear, an active process in outer hair cells amplifies and sharpen ...
... hair cells. This frequency-dependent wave profile is brought about by an interplay between longitudinal fluid coupling and local displacement of the cochlear partition, whose stiffness and mass are graded (Lighthill, 1981). In a normal ear, an active process in outer hair cells amplifies and sharpen ...
Novel Multiprotein Complexes Identified in the Hyperthermophilic
... are essential to life (1). More often than not the functional units are assemblies composed of multiple proteins (2). Many biological processes involve multiprotein complexes that function as large and efficient machines, such as ribosomes (3, 4), flagella (5), and cellulosomes (6). In addition, the ...
... are essential to life (1). More often than not the functional units are assemblies composed of multiple proteins (2). Many biological processes involve multiprotein complexes that function as large and efficient machines, such as ribosomes (3, 4), flagella (5), and cellulosomes (6). In addition, the ...
Lecture 8
... • VASP binds to the proline-rich region of ActA and binds actin – Discovered by looking for host cell factors that would bind to ActA – Associated with F-actin and focal adhesions in lamellae ...
... • VASP binds to the proline-rich region of ActA and binds actin – Discovered by looking for host cell factors that would bind to ActA – Associated with F-actin and focal adhesions in lamellae ...
Target or barrier? The cell wall of early- and later
... 2004). The evidence that Cd might increase the activity of cell wall-bound coniferyl alcohol peroxidase is of particular interest because this enzymatic activity metabolizes coniferyl alcohol, a monolignol used as substrate presumably involved in the lignification process (Quiroga et al., 2001). Thi ...
... 2004). The evidence that Cd might increase the activity of cell wall-bound coniferyl alcohol peroxidase is of particular interest because this enzymatic activity metabolizes coniferyl alcohol, a monolignol used as substrate presumably involved in the lignification process (Quiroga et al., 2001). Thi ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.