Pick, L
... pair-rule genes [Jurgens et al., 1984; Nüsslein-Volhard et al., 1984, 1985; Nüsslein-Volhard and Wieschaus, 1980; Wieschaus et al., 1984). Mutations in the pairrule genes result in lethality accompanied by deletions of alternating regions of the body. The periodic deletions caused by the eight dif ...
... pair-rule genes [Jurgens et al., 1984; Nüsslein-Volhard et al., 1984, 1985; Nüsslein-Volhard and Wieschaus, 1980; Wieschaus et al., 1984). Mutations in the pairrule genes result in lethality accompanied by deletions of alternating regions of the body. The periodic deletions caused by the eight dif ...
SPECIFIC PROTEIN SYNTHESIS IN CELLULAR
... characteristic developmental kinetics of synthesis . Each is synthesized as a separate polypeptide, apparently on monocistronic messenger RNA (mRNA), and thus reflects the expression of a distinct gene . The rapid changes in this tissue do not result from corresponding changes in translational effic ...
... characteristic developmental kinetics of synthesis . Each is synthesized as a separate polypeptide, apparently on monocistronic messenger RNA (mRNA), and thus reflects the expression of a distinct gene . The rapid changes in this tissue do not result from corresponding changes in translational effic ...
Nucleoli: Composition, Function, and Dynamics
... Arabidopsis nucleoli. Of particular interest was that aberrantly spliced mRNAs were enriched in the nucleolus and the vast majority contained premature termination codons, and therefore were likely to be turned over by the nonsense-mediated decay (NMD) pathway (Kim et al., 2009). Further, the locali ...
... Arabidopsis nucleoli. Of particular interest was that aberrantly spliced mRNAs were enriched in the nucleolus and the vast majority contained premature termination codons, and therefore were likely to be turned over by the nonsense-mediated decay (NMD) pathway (Kim et al., 2009). Further, the locali ...
cell-substratum adhesion of neurite growth cones, and its role in
... of a nerve fiber may also be adherent to the substratum. The interference reflection images of growth cones cultured on polylysine are complex, ranging from white to black in many areas. Beneath the bases of growth cones are large black zones of close contact, though the most interesting areas are a ...
... of a nerve fiber may also be adherent to the substratum. The interference reflection images of growth cones cultured on polylysine are complex, ranging from white to black in many areas. Beneath the bases of growth cones are large black zones of close contact, though the most interesting areas are a ...
We have found that an H3K27 methyltransferase activity co
... and Ezh2 is shown, ideally in non-transfected cells. Also, being Ezh2 activity regulated postranslationally, for instance by Akt-dependent phosphorylation, the possible effects of NIPP1 on Ezh2 modifications (since general stability seems not affected) could be looked into. The same for NIPP1 associ ...
... and Ezh2 is shown, ideally in non-transfected cells. Also, being Ezh2 activity regulated postranslationally, for instance by Akt-dependent phosphorylation, the possible effects of NIPP1 on Ezh2 modifications (since general stability seems not affected) could be looked into. The same for NIPP1 associ ...
Gene Section ADAM12 (ADAM metallopeptidase domain 12 (meltrin alpha))
... ADAM-12S stimulates bone growth in ADAM-12S transgenic mice by modulating chondrocyte proliferation. Interestingly, the proteinase activity of ADAM-12 is necessary for the increased growth of bone tissues since mice expressing a truncated form of ADAM-12 lacking the pro- and metalloproteinase domain ...
... ADAM-12S stimulates bone growth in ADAM-12S transgenic mice by modulating chondrocyte proliferation. Interestingly, the proteinase activity of ADAM-12 is necessary for the increased growth of bone tissues since mice expressing a truncated form of ADAM-12 lacking the pro- and metalloproteinase domain ...
Proteins - The Open University
... biological reactions, are the largest functional group of proteins. Whilst there are thousands of different enzymes, all catalysing different reactions, they do have some features in common and can often be identified as members of a particular family of enzymes. Mechanical support Typically, suppor ...
... biological reactions, are the largest functional group of proteins. Whilst there are thousands of different enzymes, all catalysing different reactions, they do have some features in common and can often be identified as members of a particular family of enzymes. Mechanical support Typically, suppor ...
Site-Directed Mutagenesis of Predicted Active Site Residues in
... resulted in a reduced Vmax value along with an increase in Km (Fig. 3 and Table 4). A glutamate implicated in catalysis is typically found next to one of the zinc ligands in both biand mononuclear zinc metallopeptidases (Rowsell et al., 1997). 4) The S454A mutant had a decrease in Vmax. 5) The Y552F ...
... resulted in a reduced Vmax value along with an increase in Km (Fig. 3 and Table 4). A glutamate implicated in catalysis is typically found next to one of the zinc ligands in both biand mononuclear zinc metallopeptidases (Rowsell et al., 1997). 4) The S454A mutant had a decrease in Vmax. 5) The Y552F ...
Lecture 6 th week
... 1. Regulation of the respiratory activity Dorsal respiratory group • Sets the basic respiratory rate. • Stimulates the inspiratory muscles to contract (diaphragm). • The signals it sends for inspiration start weakly and steadily increase for ~ 2 sec. This is called a ramp and produces a gradual ins ...
... 1. Regulation of the respiratory activity Dorsal respiratory group • Sets the basic respiratory rate. • Stimulates the inspiratory muscles to contract (diaphragm). • The signals it sends for inspiration start weakly and steadily increase for ~ 2 sec. This is called a ramp and produces a gradual ins ...
Immune complexes formed following the binding of
... arterial and venular circulation. This can lead to limb- and life-threatening complications. Although the precise mechanism(s) of thrombosis is yet unestablished, evidence in literature supports a role for activated platelets, resulting procoagulants, and microparticles.13 Immune complexes also bind ...
... arterial and venular circulation. This can lead to limb- and life-threatening complications. Although the precise mechanism(s) of thrombosis is yet unestablished, evidence in literature supports a role for activated platelets, resulting procoagulants, and microparticles.13 Immune complexes also bind ...
Cytoplasmic Actin in Neuronal Processes as a Possible Mediator of
... disrupt the plasma membrane (25). Since this interaction of saponin with the membrane is independent of fixation with low concentrations of glutaraldehyde, a better tissue preservation can be obtained than if the permeation is done without the prefixation. In comparison to the formerly used glycerin ...
... disrupt the plasma membrane (25). Since this interaction of saponin with the membrane is independent of fixation with low concentrations of glutaraldehyde, a better tissue preservation can be obtained than if the permeation is done without the prefixation. In comparison to the formerly used glycerin ...
Dominant-Negative Receptor Uncovers
... putative -subunit of the heterotrimeric G-proteins, which are known to transduce signals via seven transmembrane G-protein–coupled receptors in animals (Lease et al., 2001b). It remains to be determined how heterotrimeric G-proteins interact with the ERECTA LRR-RLK signaling pathway. We sought to d ...
... putative -subunit of the heterotrimeric G-proteins, which are known to transduce signals via seven transmembrane G-protein–coupled receptors in animals (Lease et al., 2001b). It remains to be determined how heterotrimeric G-proteins interact with the ERECTA LRR-RLK signaling pathway. We sought to d ...
Proteomic analyses of Oryza sativa mature pollen reveal novel
... polarity and cell recognition of pollen-stigma, and initiation of a hierarchical signal cascade. Recently, several proteins identified in the mature pollen of some species have been shown to be involved in hydration, cohesion and cell recognition of pollen-stigma [2–4]. The importance of tip-focused ...
... polarity and cell recognition of pollen-stigma, and initiation of a hierarchical signal cascade. Recently, several proteins identified in the mature pollen of some species have been shown to be involved in hydration, cohesion and cell recognition of pollen-stigma [2–4]. The importance of tip-focused ...
Mechanisms of size control Christopher J Potter* and
... The preceding studies suggest that these known methods of regulating cell proliferation can be separated from organ size control. However, differences in organ size between species are most often a result of changes in cell number [2]. Thus, it is likely that organ size control does exert its effect ...
... The preceding studies suggest that these known methods of regulating cell proliferation can be separated from organ size control. However, differences in organ size between species are most often a result of changes in cell number [2]. Thus, it is likely that organ size control does exert its effect ...
File
... Occurs in the liver and skeletal muscles, but it can occur in every tissue to some extent. Limitations of storage: In humans, the liver may contain as much as 4 to 6 per cent of glycogen as per weight of the organ, when analysed shortly after a meal, high in carbohydrate. After 12 to 18 hours of ...
... Occurs in the liver and skeletal muscles, but it can occur in every tissue to some extent. Limitations of storage: In humans, the liver may contain as much as 4 to 6 per cent of glycogen as per weight of the organ, when analysed shortly after a meal, high in carbohydrate. After 12 to 18 hours of ...
chest wall tumors
... Benign chest wall tumors are uncommon lesions that originate from blood vessels, nerves, bone, cartilage, or fat. Chest radiography is an important technique for evaluation of such tumors, especially those that originate from bone, because it can depict mineralization and thus indicate the diagnosis ...
... Benign chest wall tumors are uncommon lesions that originate from blood vessels, nerves, bone, cartilage, or fat. Chest radiography is an important technique for evaluation of such tumors, especially those that originate from bone, because it can depict mineralization and thus indicate the diagnosis ...
Defects in ER–endosome contacts impact lysosome function in
... 2015; Varga et al., 2015). No mechanism linking these subsets into a unifying disease pathway is known, although spastin has been implicated in two of these processes, hinting that there may be some connection. Here we investigate the role of spastin in endosomal tubule fission and examine consequen ...
... 2015; Varga et al., 2015). No mechanism linking these subsets into a unifying disease pathway is known, although spastin has been implicated in two of these processes, hinting that there may be some connection. Here we investigate the role of spastin in endosomal tubule fission and examine consequen ...
Review - Wesleyan University
... MAG through Rho-GTPase signaling to the actin cytoskeleton. (OMgp, oligodendrocyte-myelin glycoprotein; MAG, myelin associated glycoprotein; see text for details.). ...
... MAG through Rho-GTPase signaling to the actin cytoskeleton. (OMgp, oligodendrocyte-myelin glycoprotein; MAG, myelin associated glycoprotein; see text for details.). ...
1 Nucleoli: Composition, Function and Dynamics
... interspersed with them, and it is merely an assumption that all rDNA repeats are potentially transcribable. As with other genomic regions, current models suggest that ...
... interspersed with them, and it is merely an assumption that all rDNA repeats are potentially transcribable. As with other genomic regions, current models suggest that ...
Regulation of epidermal growth factor receptor signalling by
... trans autophosphorylation of tyrosine residues located in the receptor C-terminal tail (red circles) generates docking sites for the phosphorylated-tyrosine-binding modules (not shown here) found on various signalling proteins, thereby igniting downstream signalling (Lemmon and Schlessinger, 2010). ...
... trans autophosphorylation of tyrosine residues located in the receptor C-terminal tail (red circles) generates docking sites for the phosphorylated-tyrosine-binding modules (not shown here) found on various signalling proteins, thereby igniting downstream signalling (Lemmon and Schlessinger, 2010). ...
Mechanisms and Evolution of Virulence in Oomycetes
... and reactive oxygen species (ROS)], and in the case of biotrophic and hemibiotrophic pathogens, programmed cell death (PCD) (45). Successful pathogens, including oomycetes, must avoid, suppress, or tolerate these defenses, as well as gain nutrition from the host (108). Inducible plant defenses consi ...
... and reactive oxygen species (ROS)], and in the case of biotrophic and hemibiotrophic pathogens, programmed cell death (PCD) (45). Successful pathogens, including oomycetes, must avoid, suppress, or tolerate these defenses, as well as gain nutrition from the host (108). Inducible plant defenses consi ...
scf and cullin/ring h2-based
... of proteins and to switch cellular regulatory circuits from one state to another by abrupt elimination of control proteins. In eukaryotes, the bulk of the protein degradation that occurs in the cytoplasm and nucleus is carried out by the 26S proteasome. In turn, most proteins are thought to be targe ...
... of proteins and to switch cellular regulatory circuits from one state to another by abrupt elimination of control proteins. In eukaryotes, the bulk of the protein degradation that occurs in the cytoplasm and nucleus is carried out by the 26S proteasome. In turn, most proteins are thought to be targe ...
Molecular events associated with acquisition of heat
... activity. The trehalose accumulation with glucose limitation is due to an inactivation of neutral trehalase and a reversal of the catabolite inactivation of trehalose-6-phosphate synthase-phosphatase that both reflect lowered cAMP-PK activity [29,31,36]. Loss of cAMP-PK action also leads to an inact ...
... activity. The trehalose accumulation with glucose limitation is due to an inactivation of neutral trehalase and a reversal of the catabolite inactivation of trehalose-6-phosphate synthase-phosphatase that both reflect lowered cAMP-PK activity [29,31,36]. Loss of cAMP-PK action also leads to an inact ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.