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... and the structure of the beak region of the 40S subunit are reorganized. Our data indicate that the beak RNA remains flexible while Rps3 is not tightly integrated into the 40S subunit. Hrr25-dependent phosphorylation and subsequent dephosphorylation are required for Rps3 to achieve its final associa ...
... and the structure of the beak region of the 40S subunit are reorganized. Our data indicate that the beak RNA remains flexible while Rps3 is not tightly integrated into the 40S subunit. Hrr25-dependent phosphorylation and subsequent dephosphorylation are required for Rps3 to achieve its final associa ...
Regulation of tubulin heterodimer partitioning during interphase and
... partitioning in all three human cell model systems studied. Moreover, consistent with phosphorylation-inactivation of these two proteins during mitosis, we found that the microtubule-regulatory activities of both MAP4 and Op18 were only evident in interphase cells. Importantly, by employing a system ...
... partitioning in all three human cell model systems studied. Moreover, consistent with phosphorylation-inactivation of these two proteins during mitosis, we found that the microtubule-regulatory activities of both MAP4 and Op18 were only evident in interphase cells. Importantly, by employing a system ...
Introduction-to-OBO - Buffalo Ontology Site
... We need to annotate this data to allow retrieval and integration of – sequence and protein data for pathogens – case report data for patients – clinical trial data for drugs, vaccines – epidemiological data for surveillance, ...
... We need to annotate this data to allow retrieval and integration of – sequence and protein data for pathogens – case report data for patients – clinical trial data for drugs, vaccines – epidemiological data for surveillance, ...
lengthened g1 phase indicates differentiation status in
... Human embryonic stem cells (hESC) are defined by their ability to self-renew indefinitely in culture while maintaining the developmental potential to differentiate into any cell type representative of the adult body. A less commonly discussed defining characteristic of hESC is their unique cell cycl ...
... Human embryonic stem cells (hESC) are defined by their ability to self-renew indefinitely in culture while maintaining the developmental potential to differentiate into any cell type representative of the adult body. A less commonly discussed defining characteristic of hESC is their unique cell cycl ...
Estrogen Actions Throughout the Brain
... neurons, and the basal forebrain cholinergic system as well as the hippocampal formation, a brain region involved in spatial and declarative memory. Thus, ovarian steroids have measurable effects on affective state as well as cognition, with implications for dementia. Two actions are discussed in th ...
... neurons, and the basal forebrain cholinergic system as well as the hippocampal formation, a brain region involved in spatial and declarative memory. Thus, ovarian steroids have measurable effects on affective state as well as cognition, with implications for dementia. Two actions are discussed in th ...
Endothelial Cells Exposed To Fluid Shear Stress
... The effects of shear stresses on migration ratio were shown in Figure 2. The migration ratio of the static group was 1.8 times higher than that of the control. Shear stress of 0.1 Pa did not suppress the migration of SMCs compared with the static group. Shear stress of 1.5 Pa decreased significantly ...
... The effects of shear stresses on migration ratio were shown in Figure 2. The migration ratio of the static group was 1.8 times higher than that of the control. Shear stress of 0.1 Pa did not suppress the migration of SMCs compared with the static group. Shear stress of 1.5 Pa decreased significantly ...
Fractalkine is a “find-me” signal released by neurons
... modulate their clearance (Ravichandran and Lorenz, 2007), and the chemokine fractalkine has been described as one of many “find me” signals released by apoptotic cells (Truman et al., 2008). Fractalkine is a transmembrane chemokine that is cleaved constitutively by matrix metalloprotease ADAM10 and i ...
... modulate their clearance (Ravichandran and Lorenz, 2007), and the chemokine fractalkine has been described as one of many “find me” signals released by apoptotic cells (Truman et al., 2008). Fractalkine is a transmembrane chemokine that is cleaved constitutively by matrix metalloprotease ADAM10 and i ...
Poster
... Fatal prion diseases, such as Creutzfeldt-Jakob disease in humans, are associated with the conversion of the normally folded mammalian PrP protein to a misfolded prion form that aggregates. Understanding how prions behave has been greatly facilitated by the study of prions in Saccharomyces cerevisia ...
... Fatal prion diseases, such as Creutzfeldt-Jakob disease in humans, are associated with the conversion of the normally folded mammalian PrP protein to a misfolded prion form that aggregates. Understanding how prions behave has been greatly facilitated by the study of prions in Saccharomyces cerevisia ...
Adiponectin - Pomona College
... sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes. 50:1126–1133 Kadowaki T., and Yamauchi T. (2005) Adiponectin and Adiponectin Receptors. Endocrine Reviews. 26(3): 439-451. Kadowaki T. et al.(2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes ...
... sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes. 50:1126–1133 Kadowaki T., and Yamauchi T. (2005) Adiponectin and Adiponectin Receptors. Endocrine Reviews. 26(3): 439-451. Kadowaki T. et al.(2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes ...
Usha`s project - The University of Texas at Dallas
... Traditionally, proteins with similar amino acid sequences are used to infer the structure and function of a protein. This is because it was assumed that proteins with similar sequences have similar functions and structures and are evolutionary related.. However sequence similarity searches can evolu ...
... Traditionally, proteins with similar amino acid sequences are used to infer the structure and function of a protein. This is because it was assumed that proteins with similar sequences have similar functions and structures and are evolutionary related.. However sequence similarity searches can evolu ...
Penetration and Establishment of Phakopsora pachyrhizi in
... epidermal cell wall using cuticle-dissolving enzymes (cutinases) and cell-wall-digesting enzymes such as cellulases and hemicellulases (8). Other biotrophic fungi, including most rust pathogens, penetrate the host indirectly by first entering into the leaf mesophyll through stomata and then breachin ...
... epidermal cell wall using cuticle-dissolving enzymes (cutinases) and cell-wall-digesting enzymes such as cellulases and hemicellulases (8). Other biotrophic fungi, including most rust pathogens, penetrate the host indirectly by first entering into the leaf mesophyll through stomata and then breachin ...
PDF
... Porter et al., 1996). It is postulated that Ihh moves through the extracellular matrix (ECM) to reach its target cells by forming multimeric aggregates (Chen et al., 2004; Vyas et al., 2008) or by association with lipoprotein particles known as argosomes (Eaton, 2006; Panakova et al., 2005). The ECM ...
... Porter et al., 1996). It is postulated that Ihh moves through the extracellular matrix (ECM) to reach its target cells by forming multimeric aggregates (Chen et al., 2004; Vyas et al., 2008) or by association with lipoprotein particles known as argosomes (Eaton, 2006; Panakova et al., 2005). The ECM ...
FOG1 recruits the NuRD repressor complex to mediate
... lighted by the observation that patients and mice with a point mutation at valine 205 in the N-terminal zinc-finger of GATA-1 that impairs FOG-1 binding suffer from severe anemia (Nichols et al, 2000; Chang et al, 2002). It has been considered that this mutation might disrupt the interaction with add ...
... lighted by the observation that patients and mice with a point mutation at valine 205 in the N-terminal zinc-finger of GATA-1 that impairs FOG-1 binding suffer from severe anemia (Nichols et al, 2000; Chang et al, 2002). It has been considered that this mutation might disrupt the interaction with add ...
Thin Filaments - Mount Carmel Academy
... Cross Bridges on Myosin Filaments Notice that the midparts of myosin filaments are ...
... Cross Bridges on Myosin Filaments Notice that the midparts of myosin filaments are ...
Matricellular Protein Cyr61 Bridges Lysophosphatidic Acid and
... Cyr61 in LPA-induced SMC migration and related molecular mechanisms. LPA elicits cellular responses mainly via its cognate G-protein coupled receptors (11). At least six specific G-protein-coupled receptors that trigger LPA signaling pathways have been identified: LPA1– 6 (12). It has also been show ...
... Cyr61 in LPA-induced SMC migration and related molecular mechanisms. LPA elicits cellular responses mainly via its cognate G-protein coupled receptors (11). At least six specific G-protein-coupled receptors that trigger LPA signaling pathways have been identified: LPA1– 6 (12). It has also been show ...
Effect of nanoparticles on the activity of the electrone ion pumps in
... MP is the integral indication of its physiological state and depends on cell metobolism. MP in plant cells is generized as the result of both active ion pumps and also passive diffusion channel activities. The activity of active ion pumps in cells depends on metobolism level and its change happens a ...
... MP is the integral indication of its physiological state and depends on cell metobolism. MP in plant cells is generized as the result of both active ion pumps and also passive diffusion channel activities. The activity of active ion pumps in cells depends on metobolism level and its change happens a ...
The ventral and posterior expression of the zebrafish homeobox
... essentially of a ventral type, although a small region of dorsal type mesoderm, the organizer, is present near the dorsal midline. During gastrulation, most cells converge to the dorsal side of the embryo and are thus located in the range of a dorsalizing signal emitted by the organizer. Most embryo ...
... essentially of a ventral type, although a small region of dorsal type mesoderm, the organizer, is present near the dorsal midline. During gastrulation, most cells converge to the dorsal side of the embryo and are thus located in the range of a dorsalizing signal emitted by the organizer. Most embryo ...
Document
... and interactions with NCAM (Neural Cell Adhesion Molecule) at the neuronal surface, PrP is implicated in neurite outgrough via signal transduction pathways including the activation of Fyn kinases [17, 35, 109]. In another study it has been shown that the coupling of PrPC to Fyn is dependent on caveo ...
... and interactions with NCAM (Neural Cell Adhesion Molecule) at the neuronal surface, PrP is implicated in neurite outgrough via signal transduction pathways including the activation of Fyn kinases [17, 35, 109]. In another study it has been shown that the coupling of PrPC to Fyn is dependent on caveo ...
The Adenosine Story Goes Ionic: CaV2.1
... receptor subtypes A1 and A2A, adenosine exerts diverse neuromodulatory actions throughout the brain.6 A1 receptors are inhibitory, Gi-coupled receptors widely expressed in wake-active areas and central to adenosine’s sleep promotion.2 But many questions about how adenosine relates to sleep homeostas ...
... receptor subtypes A1 and A2A, adenosine exerts diverse neuromodulatory actions throughout the brain.6 A1 receptors are inhibitory, Gi-coupled receptors widely expressed in wake-active areas and central to adenosine’s sleep promotion.2 But many questions about how adenosine relates to sleep homeostas ...
Medical Physiology
... No intrinsic kinase activity Intracellular domain associate with JAK and Src Dimerization to activate tyrosine kinase Receptor guanylyl cyclase Atrial natriuretic peptide (ANP) GC-A receptor Ligand bind to dimerize intracellular guanylyl cyclase domains Becomes activated Convert GTP to cGMP cGMP act ...
... No intrinsic kinase activity Intracellular domain associate with JAK and Src Dimerization to activate tyrosine kinase Receptor guanylyl cyclase Atrial natriuretic peptide (ANP) GC-A receptor Ligand bind to dimerize intracellular guanylyl cyclase domains Becomes activated Convert GTP to cGMP cGMP act ...
Germline stem cell niches
... 5. Commonalities and differences in different GSC niches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 6. Conclusions and future directions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 ...
... 5. Commonalities and differences in different GSC niches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 6. Conclusions and future directions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 ...
Nervous Tissue - Essex County College Faculty Web Server
... • Neurons are electrically excitable due to the voltage difference across their membrane • Communicate with 2 types of electric signals – action potentials that can travel long distances – graded potentials that are local membrane changes only ...
... • Neurons are electrically excitable due to the voltage difference across their membrane • Communicate with 2 types of electric signals – action potentials that can travel long distances – graded potentials that are local membrane changes only ...
cell biology - Bio
... The overall theme for the book is the cell as the unit of life. We begin (Chapters 1–3) by describing the components of the cell as seen under the microscope. We then (Chapters 4–8) turn to the central dogma of molecular biology and describe how DNA is used to make RNA which in turn is used to make ...
... The overall theme for the book is the cell as the unit of life. We begin (Chapters 1–3) by describing the components of the cell as seen under the microscope. We then (Chapters 4–8) turn to the central dogma of molecular biology and describe how DNA is used to make RNA which in turn is used to make ...
Chapter 16—Probes for Endocytosis, Receptors and Ion Channels
... 16.1 Probes for Following Receptor Binding and Phagocytosis The plasma membrane defines the inside and outside of the cell. It not only encloses the cytosol to maintain the intracellular environment but also serves as a formidable barrier to the extracellular environment. Because cells require input ...
... 16.1 Probes for Following Receptor Binding and Phagocytosis The plasma membrane defines the inside and outside of the cell. It not only encloses the cytosol to maintain the intracellular environment but also serves as a formidable barrier to the extracellular environment. Because cells require input ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.