Cellular function and pathological role of ATP13A2 and related P
... P-type ATPases are biological pumps omnipresent in all forms of life, which are recognized by several conserved signature motifs associated with their catalytic mechanism (Axelsen and Palmgren, 1998). The main characteristic of all P-type ATPases is the formation of an acid-stable aspartyl phosphate ...
... P-type ATPases are biological pumps omnipresent in all forms of life, which are recognized by several conserved signature motifs associated with their catalytic mechanism (Axelsen and Palmgren, 1998). The main characteristic of all P-type ATPases is the formation of an acid-stable aspartyl phosphate ...
Staphylococcus aureus Complement-Independent Phagocytosis of
... (1). Based on their localization, PRRs are classified as either cell-associated receptors, including the Toll-like receptors (2) and scavenger receptors (3), or fluid-phase molecules (4). Fluidphase molecules, such as collectins, ficolins, and pentraxins, constitute the humoral arm of the innate imm ...
... (1). Based on their localization, PRRs are classified as either cell-associated receptors, including the Toll-like receptors (2) and scavenger receptors (3), or fluid-phase molecules (4). Fluidphase molecules, such as collectins, ficolins, and pentraxins, constitute the humoral arm of the innate imm ...
Biogenesis, Turnover, and Mode of Action of Plant
... MicroRNAs (miRNAs) are a class of 20- to 24-nucleotide endogenous small RNAs that repress gene expression. In plants, miRNAs control the expression of genes encoding transcription factors, stress response proteins, and other proteins that impact the development, growth, and physiology of plants. The ...
... MicroRNAs (miRNAs) are a class of 20- to 24-nucleotide endogenous small RNAs that repress gene expression. In plants, miRNAs control the expression of genes encoding transcription factors, stress response proteins, and other proteins that impact the development, growth, and physiology of plants. The ...
PDQ Physiology
... permits unhindered exchange of ions, mRNA, ribosomes, and small proteins (up to 5 kilodaltons [kDa]). ...
... permits unhindered exchange of ions, mRNA, ribosomes, and small proteins (up to 5 kilodaltons [kDa]). ...
characterization of proteins from the cytoskeleton of giardia lamblia
... (Sheir-Neiss, Lai & Morris, 1978; Water & Kleinsmith, 1976) and different organelles (McKeithan&Rosenbaum, 1981), showing that normally segregated tubulin species are competent to co-assemble. To explain structural diversity of microtubules in vivo, one possibility is that assembly is specifically m ...
... (Sheir-Neiss, Lai & Morris, 1978; Water & Kleinsmith, 1976) and different organelles (McKeithan&Rosenbaum, 1981), showing that normally segregated tubulin species are competent to co-assemble. To explain structural diversity of microtubules in vivo, one possibility is that assembly is specifically m ...
Calcium oscillations in higher plants Nicola H Evans*, Martin R
... cytosol are likely to form the basis of any mechanism that generates [Ca2+]cyt oscillations. These fluxes include influx and efflux across the plasma membrane and release and uptake into intracellular stores [2], including a contribution from the nucleus [6,7]. Accordingly, it is likely that oscilla ...
... cytosol are likely to form the basis of any mechanism that generates [Ca2+]cyt oscillations. These fluxes include influx and efflux across the plasma membrane and release and uptake into intracellular stores [2], including a contribution from the nucleus [6,7]. Accordingly, it is likely that oscilla ...
Golgi-targeting sequence of p230 - Journal of Cell Science
... suggesting that the conformation of the domain is critical for efficient targeting. In COS cells expressing high levels of GFP-p230-C98aa fusion protein, endogenous p230 was no longer associated with Golgi membranes, suggesting that the GFP fusion protein and endogenous p230 may compete for the same ...
... suggesting that the conformation of the domain is critical for efficient targeting. In COS cells expressing high levels of GFP-p230-C98aa fusion protein, endogenous p230 was no longer associated with Golgi membranes, suggesting that the GFP fusion protein and endogenous p230 may compete for the same ...
Chromoplast Differentiation: Current Status and
... attract insects and mammals so as to facilitate flower pollination and seed dispersal. One of these strategies has been the development of bright colors, most often within a type of plastid called chromoplasts. Chromoplasts are responsible for the yellow, orange and red colors of many flowers and frui ...
... attract insects and mammals so as to facilitate flower pollination and seed dispersal. One of these strategies has been the development of bright colors, most often within a type of plastid called chromoplasts. Chromoplasts are responsible for the yellow, orange and red colors of many flowers and frui ...
The Role of PME-1 in Cancer: Therapeutic Implications
... Protein phosphorylation plays an important role in the cellular signaling, by conveying cell proliferation, survival, and death signals across the cellular machinery. Protein kinases and phosphatases regulate the phosphorylation status of thousands of proteins in a cell, and thereby maintain a state ...
... Protein phosphorylation plays an important role in the cellular signaling, by conveying cell proliferation, survival, and death signals across the cellular machinery. Protein kinases and phosphatases regulate the phosphorylation status of thousands of proteins in a cell, and thereby maintain a state ...
Progress in understanding the role of microtubules in plant cells
... ogists, biological systems seem to have become more complex, and long-held concepts have begun to crumble. This is very well illustrated in the study of microtubule function in plant cells. Since their first clear description in 1963 in a publication by Ledbetter and Porter [1], in which the term ‘m ...
... ogists, biological systems seem to have become more complex, and long-held concepts have begun to crumble. This is very well illustrated in the study of microtubule function in plant cells. Since their first clear description in 1963 in a publication by Ledbetter and Porter [1], in which the term ‘m ...
Determination of Binding Sites of Cadherin Peptides on the EC1
... the binding activity of the N-terminus of E-cadherin. At low protein concentration, intramolecular binding of tryptophan-2 (W2) side-chain into the W2 pocket on the same molecule was detected via chemical shift changes. However, at high protein concentration, the X-ray structure indicates that two m ...
... the binding activity of the N-terminus of E-cadherin. At low protein concentration, intramolecular binding of tryptophan-2 (W2) side-chain into the W2 pocket on the same molecule was detected via chemical shift changes. However, at high protein concentration, the X-ray structure indicates that two m ...
The role of nicotinic acetylcholine receptors and GABAergic
... Epilepsy is a common neurological disorder, affecting approximately 0.5-1% of the world population (Hirtz et al., 2007). This disorder is characterized by the occurrence of seizures, which can manifest in different symptoms, such as wild involuntary movements or absences. In general, epilepsy syndro ...
... Epilepsy is a common neurological disorder, affecting approximately 0.5-1% of the world population (Hirtz et al., 2007). This disorder is characterized by the occurrence of seizures, which can manifest in different symptoms, such as wild involuntary movements or absences. In general, epilepsy syndro ...
Microsoft Word (manuscript)
... Furthermore, DPM3 alone was able to stabilize DPM1 and DPM synthase had an enzymatic activity without the DPM2 subunit, however, the activity was ten-fold higher when DPM2 was present as well. It is not known why in some organisms the structure of DPM synthase is so complex; it has been suggested th ...
... Furthermore, DPM3 alone was able to stabilize DPM1 and DPM synthase had an enzymatic activity without the DPM2 subunit, however, the activity was ten-fold higher when DPM2 was present as well. It is not known why in some organisms the structure of DPM synthase is so complex; it has been suggested th ...
Chapter18_Section03_JKedit
... The kingdom Protista is composed of eukaryotic organisms that cannot be classified as animals, plants, or fungi. Its members display the greatest variety. They can be unicellular or multicellular; photosynthetic or heterotrophic; and can share characteristics with plants, fungi, or animals. Slide 19 ...
... The kingdom Protista is composed of eukaryotic organisms that cannot be classified as animals, plants, or fungi. Its members display the greatest variety. They can be unicellular or multicellular; photosynthetic or heterotrophic; and can share characteristics with plants, fungi, or animals. Slide 19 ...
Bil 255 – CMB
... 1 NADH (via mito ETC) = 3 ATP and 1 FADH2 = 2 ATP beta-OXIDATION 6C-FFA (c-c-c-c-c-c) ...
... 1 NADH (via mito ETC) = 3 ATP and 1 FADH2 = 2 ATP beta-OXIDATION 6C-FFA (c-c-c-c-c-c) ...
Nestin Is Required for the Proper SelfRenewal of Neural Stem Cells
... cells capable of proliferation and differentiation. The correlation of nestin expression with cell proliferation is also observed in neoplastic transformation. For example, abundant nestin expression was found in several cancers such as neuroblastoma, glioma, and melanoma and higher levels of expres ...
... cells capable of proliferation and differentiation. The correlation of nestin expression with cell proliferation is also observed in neoplastic transformation. For example, abundant nestin expression was found in several cancers such as neuroblastoma, glioma, and melanoma and higher levels of expres ...
Membrane Potential Fluctuations in Neural Integrator
... provide input for multiple target neurons. While information generally flows from the dendrite to the soma to the axon to the target dendrite, examples exist for direct dendro-dendritic [51] or dendro-axonal connections [52]. Information flows into neurons through synapses. Neurotransmitter diffuse ...
... provide input for multiple target neurons. While information generally flows from the dendrite to the soma to the axon to the target dendrite, examples exist for direct dendro-dendritic [51] or dendro-axonal connections [52]. Information flows into neurons through synapses. Neurotransmitter diffuse ...
Macrocyclic Carbohydrate/Amino Acid Hybrid Molecules
... membranes, and mediate cell adhesion in tissue formation. Proteins also have many other functions and it would be difficult to find a process in a living cell where proteins are not involved. In many of these processes, proteins need to bind to other molecules in binding sites on their surfaces. In ...
... membranes, and mediate cell adhesion in tissue formation. Proteins also have many other functions and it would be difficult to find a process in a living cell where proteins are not involved. In many of these processes, proteins need to bind to other molecules in binding sites on their surfaces. In ...
ecoli lysis - KSU Faculty Member websites
... and neurotransmitters of the enteric nervous system also play a role in the induction of fluid secretion by LT (5, 6). Although a great deal is known about the structure and biological activity of LT, little is known about the mechanism of its secretion by ETEC. LT is structurally and biologically r ...
... and neurotransmitters of the enteric nervous system also play a role in the induction of fluid secretion by LT (5, 6). Although a great deal is known about the structure and biological activity of LT, little is known about the mechanism of its secretion by ETEC. LT is structurally and biologically r ...
J Comp Physiol (1982) 149: 179 193
... to large areas of the compound eye, present a strong, instantaneous perturbation of the visual system. Several thousand photoreceptors are simultaneously excited. Their signals travel along an equally large number of parallel fibres centripetally, and along particular pathways even through the whole ...
... to large areas of the compound eye, present a strong, instantaneous perturbation of the visual system. Several thousand photoreceptors are simultaneously excited. Their signals travel along an equally large number of parallel fibres centripetally, and along particular pathways even through the whole ...
Dopamine
... DA NEURON ANATOMY AND PHYSIOLOGY Both in vivo and in vitro studies have demonstrated that DA-containing neurons in the midbrain exhibit spontaneous spike firing that is driven by an endogenous pacemaker conductance (1–3), with their activity modulated by afferent inputs. One of the prominent regulat ...
... DA NEURON ANATOMY AND PHYSIOLOGY Both in vivo and in vitro studies have demonstrated that DA-containing neurons in the midbrain exhibit spontaneous spike firing that is driven by an endogenous pacemaker conductance (1–3), with their activity modulated by afferent inputs. One of the prominent regulat ...
Cytokinin Lecture
... Cytokinin receptor mutants are insensitive to cytokinen (and see affect of cytokinin oxidase over-expression). ...
... Cytokinin receptor mutants are insensitive to cytokinen (and see affect of cytokinin oxidase over-expression). ...
Manganese Complexes: Diverse Metabolic Routes to Oxidative
... (ROS). However, many organisms can fully compensate for the loss of such enzymatic defenses by accumulating metabolites and Mn2+, which can form catalytic Mn-antioxidants. Accumulated metabolites can direct reactivity of Mn2+ with superoxide and specifically shield proteins from oxidative damage. Re ...
... (ROS). However, many organisms can fully compensate for the loss of such enzymatic defenses by accumulating metabolites and Mn2+, which can form catalytic Mn-antioxidants. Accumulated metabolites can direct reactivity of Mn2+ with superoxide and specifically shield proteins from oxidative damage. Re ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.