Nucleation and Dynamics of Golgi-derived Microtubules
... et al., 2011; Ori-Mckenney et al., 2012; Maia et al., 2013), likely because it can recruit γ-TuRC either directly, or indirectly via CDK5Rap2 or myomegalin interactions. However, AKAP450 function is not essential for MT nucleation at the Golgi in myotubes, likely because γ-TuRC is recruited to the G ...
... et al., 2011; Ori-Mckenney et al., 2012; Maia et al., 2013), likely because it can recruit γ-TuRC either directly, or indirectly via CDK5Rap2 or myomegalin interactions. However, AKAP450 function is not essential for MT nucleation at the Golgi in myotubes, likely because γ-TuRC is recruited to the G ...
Word doc
... signal cascade amplify a cell’s response? 9. What is the role of phosphorylation and dephosphorylation? What are the enzymes responsible for these modifications? What is a second messenger and how does it bring about a response in a cell? 10. What are the four common membrane receptor types? 11. Des ...
... signal cascade amplify a cell’s response? 9. What is the role of phosphorylation and dephosphorylation? What are the enzymes responsible for these modifications? What is a second messenger and how does it bring about a response in a cell? 10. What are the four common membrane receptor types? 11. Des ...
ABSTRACT SUSTAINED DELIVERY AND PHARMACODYNAMICS OF AN INTEGRIN
... choroidal neovascularization (CNV) rat model was employed to further examine the angiogenic inhibitory effect of EMD478761 from a sustained release microimplant. And in part III, the pharmacodynamics of EMD478761 was studied to reveal the mechanisms by which EMD478761 inhibited angiogenesis. Results ...
... choroidal neovascularization (CNV) rat model was employed to further examine the angiogenic inhibitory effect of EMD478761 from a sustained release microimplant. And in part III, the pharmacodynamics of EMD478761 was studied to reveal the mechanisms by which EMD478761 inhibited angiogenesis. Results ...
Development
... data support a hypothesis that (lipo)chitin oligosaccharides have mitogenic activity in various organisms. We were interested to know whether an intact LCO molecule is a prerequisite to obtaining cortical cell divisions when it is delivered inside the plant tissue or whether a substructure is suffic ...
... data support a hypothesis that (lipo)chitin oligosaccharides have mitogenic activity in various organisms. We were interested to know whether an intact LCO molecule is a prerequisite to obtaining cortical cell divisions when it is delivered inside the plant tissue or whether a substructure is suffic ...
Enzyme Mechanisms - Illinois Institute of Technology
... the enzyme. One of these involves the proximity effect, in which two (or more) substrates are directed down potential-energy gradients to positions where they are close to one another. Thus the enzyme is able to defeat the entropic difficulty of bringing substrates ...
... the enzyme. One of these involves the proximity effect, in which two (or more) substrates are directed down potential-energy gradients to positions where they are close to one another. Thus the enzyme is able to defeat the entropic difficulty of bringing substrates ...
Actin behavior in bulk cytoplasm is cell cycle regulated in early
... seem to grow in thickness (black chevrons). At the last time-points the entire gel undergoes rapid coordinated inward movement (white chevrons). The gel moves very fast once contraction starts and also tended to change in focal plane at this time point, which made it difficult to follow individual b ...
... seem to grow in thickness (black chevrons). At the last time-points the entire gel undergoes rapid coordinated inward movement (white chevrons). The gel moves very fast once contraction starts and also tended to change in focal plane at this time point, which made it difficult to follow individual b ...
Modulation of Fibroblast Growth Factor
... FGF-2 with cell-associated and free HSPGs are manyfold. HSPGs protect FGF-2 from inactivation in the extracellular environment and modulate the bioavailability of the growth factor (Saksela et al., 1988; Edelman et al., 1993). At the cell surface, free and cell-associated HSPGs may play contrasting ...
... FGF-2 with cell-associated and free HSPGs are manyfold. HSPGs protect FGF-2 from inactivation in the extracellular environment and modulate the bioavailability of the growth factor (Saksela et al., 1988; Edelman et al., 1993). At the cell surface, free and cell-associated HSPGs may play contrasting ...
reviews - bio21.bas.bg
... desiccation by glass formation (Williams and Leopold, 1989; Koster, 1991), by alterations in properties of cell membranes or by replacing water molecules at their binding site on the membranes (Crowe et al., 1992). The presence of disaccharides (trehalose or sucrose) have been found to help stabiliz ...
... desiccation by glass formation (Williams and Leopold, 1989; Koster, 1991), by alterations in properties of cell membranes or by replacing water molecules at their binding site on the membranes (Crowe et al., 1992). The presence of disaccharides (trehalose or sucrose) have been found to help stabiliz ...
Fulltext - Jultika
... enzymatically active, reducing 2E-enoyl-CoAs to acyl-CoAs in an NADPH-dependent manner. Altogether, our data showed that NRBF-1 is a mitochondrial 2-enoyl-CoA reductase/2-enoyl thioester reductase (MECR/ETR1), the human functional counterpart of yeast Etr1p. In addition, MECR was also isolated from ...
... enzymatically active, reducing 2E-enoyl-CoAs to acyl-CoAs in an NADPH-dependent manner. Altogether, our data showed that NRBF-1 is a mitochondrial 2-enoyl-CoA reductase/2-enoyl thioester reductase (MECR/ETR1), the human functional counterpart of yeast Etr1p. In addition, MECR was also isolated from ...
Adaptation of Microorganisms to Cold Temperatures, Weak Acid
... proteins), the continued synthesis of proteins involved in transcription and translation, and the repression of heat shock proteins. The addition of weak acid preservatives (for example, sorbates, benzoates) also induces a specific pattern of gene expression (for example, ‘Acid Tolerance Response’), ...
... proteins), the continued synthesis of proteins involved in transcription and translation, and the repression of heat shock proteins. The addition of weak acid preservatives (for example, sorbates, benzoates) also induces a specific pattern of gene expression (for example, ‘Acid Tolerance Response’), ...
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).
... of the protein, which revealed that the FMRP harbors several RNA-binding motifs [Ashley et al., 1993; Gibson et al., 1993; Siomi et al., 1993]. These include two tandem KH domains, so named for their homology to the RNA-binding protein hnRNP-K, and a less well-defined element consisting of repeats of ...
... of the protein, which revealed that the FMRP harbors several RNA-binding motifs [Ashley et al., 1993; Gibson et al., 1993; Siomi et al., 1993]. These include two tandem KH domains, so named for their homology to the RNA-binding protein hnRNP-K, and a less well-defined element consisting of repeats of ...
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... cardiovascular system. It is clear that thrombin aids in the formation of blood clots by catalyzing the conversion of ?brinogen to ?brin. which is an integral part of most clots. In addition. thrombin is known to act directly on cells in the blood and in the interior blood vessel wall. and speci?cal ...
... cardiovascular system. It is clear that thrombin aids in the formation of blood clots by catalyzing the conversion of ?brinogen to ?brin. which is an integral part of most clots. In addition. thrombin is known to act directly on cells in the blood and in the interior blood vessel wall. and speci?cal ...
Sixth Southeast Enzyme Conference
... The Chemistry Department at Georgia State University is the lead organizer and founder of the Southeast Enzyme Conference. This conference attracts students, research scientists and faculty members from colleges and universities throughout the southeastern region. With the assistance of the GSU Foun ...
... The Chemistry Department at Georgia State University is the lead organizer and founder of the Southeast Enzyme Conference. This conference attracts students, research scientists and faculty members from colleges and universities throughout the southeastern region. With the assistance of the GSU Foun ...
Epstein-Barr virus exploits intrinsic B-lymphocyte
... 10−100) enrichment not only for RBPJ (78%), but also for ETS (39%), EBF (39%), RUNX (43%), PU.1 (22%), and NFκB (22%) motifs, over a control set of sequences with similar GC content. These data are consistent with EBF, RELA, and PU.1 having significant affects on EBNA2 or RBPJ binding and transcripti ...
... 10−100) enrichment not only for RBPJ (78%), but also for ETS (39%), EBF (39%), RUNX (43%), PU.1 (22%), and NFκB (22%) motifs, over a control set of sequences with similar GC content. These data are consistent with EBF, RELA, and PU.1 having significant affects on EBNA2 or RBPJ binding and transcripti ...
Identification of a molecular component of the mitochondrial
... However, eukaryotic orthologues to Pat have not been identified in either the mitochondrial or nuclear genome [9]. An alternative scenario in eukaryotes could be that mitochondrial proteins are acetylated in the cytosol prior to mitochondrial import. However, as fasting and feeding result in a dynam ...
... However, eukaryotic orthologues to Pat have not been identified in either the mitochondrial or nuclear genome [9]. An alternative scenario in eukaryotes could be that mitochondrial proteins are acetylated in the cytosol prior to mitochondrial import. However, as fasting and feeding result in a dynam ...
Platelet granule exocytosis: a comparison with chromaffin cells
... Dense granules also contain factors that are vasoconstrictive such as serotonin (Flaumenhaft, 2013). Dense granules and LDCVs have been compared based on their unusually high concentrations of cations, polyphosphates, adenine nucleotides, and bioactive amines such as serotonin and histamine (Sigel a ...
... Dense granules also contain factors that are vasoconstrictive such as serotonin (Flaumenhaft, 2013). Dense granules and LDCVs have been compared based on their unusually high concentrations of cations, polyphosphates, adenine nucleotides, and bioactive amines such as serotonin and histamine (Sigel a ...
Chara Myosin and the Energy of Cytoplasmic Streaming
... whole myosin was the same as that from the isolated globular tail domain because they were both blotted onto the membrane after being denatured by SDS. If we consider the difference in the molecular weight between Chara myosin heavy chain (248,000 Da; Kashiyama et al, 2000) and the globular tail dom ...
... whole myosin was the same as that from the isolated globular tail domain because they were both blotted onto the membrane after being denatured by SDS. If we consider the difference in the molecular weight between Chara myosin heavy chain (248,000 Da; Kashiyama et al, 2000) and the globular tail dom ...
Full-Text PDF
... discuss how RA signaling is used at different steps reiteratively in the progressive specification and differentiation of both spinal cord and trunk NCCs and how it interacts with other signaling pathways. In particular, we stress how RA counteracts the effect of FGF, which maintains cells in a more ...
... discuss how RA signaling is used at different steps reiteratively in the progressive specification and differentiation of both spinal cord and trunk NCCs and how it interacts with other signaling pathways. In particular, we stress how RA counteracts the effect of FGF, which maintains cells in a more ...
DEPARTMENT OF BIOCHEMISTRY UNIVERSITY OF KERALA
... Cytoskeleton: Microtubules, Microfilaments and intermediary filaments. Extracellular matrix and cellular interactions: Extracellular Matrix components, Cell adhesion molecules, Cell – Cell communications, Cell – Cell Interaction. Cell signaling: receptors and their functions, signaling molecules, si ...
... Cytoskeleton: Microtubules, Microfilaments and intermediary filaments. Extracellular matrix and cellular interactions: Extracellular Matrix components, Cell adhesion molecules, Cell – Cell communications, Cell – Cell Interaction. Cell signaling: receptors and their functions, signaling molecules, si ...
Bugging the cell wall of bacteria
... for Lipid II in wall-less species indicate its involvement in other cellular processes, such as cell division [28]. Lipid II is a target for several classes of antibiotics, such as the glycopeptides and the lantibiotics. They share the common action of preventing incorporation of Lipid II, thereby ...
... for Lipid II in wall-less species indicate its involvement in other cellular processes, such as cell division [28]. Lipid II is a target for several classes of antibiotics, such as the glycopeptides and the lantibiotics. They share the common action of preventing incorporation of Lipid II, thereby ...
The roles of BRCA1 and BRCA2 and associated proteins in the
... and the assistance of various other proteins. The MRN complex is thought to play a role in bringing the two broken DNA ends together and the complex has also been suggested to be involved in the nucleolytic resection of the ends of the DSB. The resulting 30 overhangs become coated by RPA, which prev ...
... and the assistance of various other proteins. The MRN complex is thought to play a role in bringing the two broken DNA ends together and the complex has also been suggested to be involved in the nucleolytic resection of the ends of the DSB. The resulting 30 overhangs become coated by RPA, which prev ...
The Olfactory Sensory Map in Drosophila
... membrane proteins that is selectively expressed in OSNs in the olfactory epithelium of vertebrates and antennae of insects. ORs have selective but broad ligand‑binding properties, such that a given OR is activated by multiple odors and a given odor activates multiple ORs.15‑18 This combinato‑ rial c ...
... membrane proteins that is selectively expressed in OSNs in the olfactory epithelium of vertebrates and antennae of insects. ORs have selective but broad ligand‑binding properties, such that a given OR is activated by multiple odors and a given odor activates multiple ORs.15‑18 This combinato‑ rial c ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.