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Transforming growth factor–1 in supernatants from stored red blood
Transforming growth factor–1 in supernatants from stored red blood

... inhibit human neutrophil migration in response to formyl peptides and stimulate neutrophil locomotion. These effects can be observed with high dilutions of RBC supernatants, such as 1:5 ⴛ 106 (vol/vol), able to trigger locomotion as well as desensitization of the cells to alternative chemoattractant ...
a va i l a b l e a t... w w w. e l s e v i e...
a va i l a b l e a t... w w w. e l s e v i e...

... Introduction The Delta ligand is a type-I single pass transmembrane protein that is essential for dictating cell fate decisions during development in a number of organ systems in metazoans [1,2]. Analyses of Drosophila neurogenesis established early on that Delta acts predominantly as a ligand for N ...
How proteins produce cellular membrane curvature
How proteins produce cellular membrane curvature

... elasticity is characterized by the elastic moduli, such as the bending moduli of the membrane monolayer, κm, and bilayer, κB, the moduli of the Gaussian curvature of the monolayer and bilayer, κ m and κ B , respectively, the membrane stretching modulus, Г (see Supplementary information S1 (box) and ...
Characterization of the effects of antiepileptic drugs on bone
Characterization of the effects of antiepileptic drugs on bone

... osteoblasts. A proper equilibrium between both cell types metabolic activities is required to ensure an adequate skeletal tissue structure, and it involves resorption of old bone and formation of new bone tissue. It is reported that treatment with antiepileptic drugs (AEDs) can elicit alterations in ...
Exocytosis Precedes and Predicts the Increase in Growth in
Exocytosis Precedes and Predicts the Increase in Growth in

... 50 s (Pierson et al., 1996; Cárdenas et al., 2008). Additionally, many of the underlying processes also oscillate with the same period, but usually with a different phase than the growth rate (Holdaway-Clarke and Hepler, 2003; Chebli and Geitmann, 2007; Moreno et al., 2007). Thus, growth emerges as ...
Active Hair Bundle Movements and the Cochlear Amplifier
Active Hair Bundle Movements and the Cochlear Amplifier

... These mechanisms can vary between species, but there are some fundamental similarities used by hair cells to overcome difficulties that are common to each. One common problem faced by all hair cells is that the energy associated with sound at threshold is small. In order to obtain such low threshold ...
Cellulose Biosynthesis in Oomycetes
Cellulose Biosynthesis in Oomycetes

... Baldauf  et  al.,  2000).  The  growth  of  Oomycetes  resembles  the  growth  of  fungal  cells  that  form coenocytic hyphae. The cell wall of Oomycetes, as opposed to that of fungi, contains  cellulose. Most stages in the Oomycete life cycles are diploid (Hardham, 2007). Oomycetes  have  evolved  ...
Cleavage modification did not alter early blastomere fates
Cleavage modification did not alter early blastomere fates

... nate developmental mode allowed for the identification of homologous blastomeres across taxa ...
TBX5 is required for embryonic cardiac cell cycle - UNC
TBX5 is required for embryonic cardiac cell cycle - UNC

... distinct periods of proliferation: one that occurs during early embryogenesis and a second that takes place immediately following birth (MacLellan and Schneider, 2000; Olson and Schneider, 2003; Pasumarthi and Field, 2002). The embryonic phase of cardiac proliferation begins after cardiac cell commi ...
2 common staining technique
2 common staining technique

Protozoa - Dr Magrann
Protozoa - Dr Magrann

... bundle, pointed at tip. Cytostome – oral opening, has specific arrangement and ultrastructure of cilia for different spp. Cillia that form structures are same as other cilia with no permanent attachment between them. No known mechanisms of association of cilia. ...
The purpose of this summary is exclusively educational, to provide
The purpose of this summary is exclusively educational, to provide

... dosing; (ii) gold standard test to confirm or rule out drug hypersensitivity (in some clinical situations, it might be more useful to look for safe drug alternatives instead of performing a DPT); (iii) especially important when skin or in vitro allergy testing results are unstandardized, unavailable ...
The effects of combinations of a green tea extract and... active ingredient thereof, with standard antiretroviral drugs
The effects of combinations of a green tea extract and... active ingredient thereof, with standard antiretroviral drugs

... Growth curve of SC-1 and BM5 cells. Cells were stained with Crystal Violet and absorbency was determined at 595nm. ...
FGF signalling: diverse roles during early vertebrate embryogenesis
FGF signalling: diverse roles during early vertebrate embryogenesis

... movements, using the same primary signal, FGF. As such, the role of FGF signalling during gastrulation can be divided in two distinct elements: (1) an early, ERK-dependent transcriptional role that specifies and/or maintains axial and paraxial mesoderm; and (2) a ...
Cadaverine is Transported into Vibrio vulnificus Through its CadB in
Cadaverine is Transported into Vibrio vulnificus Through its CadB in

... forming more cadaverine. It was examined whether cadaverine, when added exogenously, was effective in protecting cells from superoxide stress. No protective effect by the exogenously added cadaverine (5 mM) was observed at pH 7.5 with both wild-type and the mutant strains (Fig. 1, A3). However, sign ...
The 14-3-3 gene par-5 is required for germline development and
The 14-3-3 gene par-5 is required for germline development and

... in the mitotic entry at the first embryonic division (Brauchle et al., 2003). Through video recordings of the first embryonic division, we observed that par-5(RNAi) and par-5(it55) embryos rescued the HU-induced cell cycle delay (supplementary material Fig. S4). Therefore, par-5 is also required for ...
PDF + SI - Development - The Company of Biologists
PDF + SI - Development - The Company of Biologists

... 1995). FCs are born from the asymmetric division of progenitor cells (PCs) specified at precise positions and times within the somatic mesoderm. Detailed characterization of a few somatic muscle lineages has established that muscle identity (specific shape, size, orientation) reflects the expression ...
Role of Sodium Channel Deglycosylation in the Genesis of Cardiac
Role of Sodium Channel Deglycosylation in the Genesis of Cardiac

... Electrophysiology—During experiments, cells were continuously superperfused with a solution (solution A) containing the following constituents (in mM): 135 NaCl 5 KCl, 2 CaCl2, 1 MgCl2, 10 HEPES, 10 glucose, pH 7.4. Myocytes were patched in this solution, and after a gigaohm seal was formed, a small ...
Grape berry vacuole: a complex and heterogeneous membrane
Grape berry vacuole: a complex and heterogeneous membrane

... Jones 2000), where some vacuoles primarily function as storage organelles and other as lytic ...
Re-establishing the avian body plan - Development
Re-establishing the avian body plan - Development

... cranially to facilitate the experiment, with the apparent left side of the blastoderm serving as the experimental side (i.e., lacking inducer) and the apparent right side serving as the control side (i.e., containing both inducer and responder); the primitive streak and 250 µm of adjacent blastoderm ...
12 October 2000
12 October 2000

... positions in the primary sequence (always after an aspartate residue). In most cases, caspase-mediated 'protein surgery' results in inactivation of the target protein (Box 1). But caspases can also activate proteins, either directly, by cleaving off a negative regulatory domain, or indirectly, by in ...
Graded potential of neural crest to form cornea, sensory neurons
Graded potential of neural crest to form cornea, sensory neurons

... and Ayer-Le Lievre, 1982). This suggested that the cranial neural crest has a broader (or at least different) developmental potential than that of trunk neural crest. However, under appropriate culture conditions, trunk neural crest cells have been shown to acquire some properties of chondrocytes (M ...
Passive transport disrupts directional path integration
Passive transport disrupts directional path integration

... the presence of the familiar landmark cue. Fourth, proprioceptive information from muscle and bone joints, along with somatic receptors, may also be used for determining how the head and body move through space, although direct evidence for their use in determining and updating directional heading i ...
Graded potential of neural crest to form cornea, sensory neurons
Graded potential of neural crest to form cornea, sensory neurons

... and Ayer-Le Lievre, 1982). This suggested that the cranial neural crest has a broader (or at least different) developmental potential than that of trunk neural crest. However, under appropriate culture conditions, trunk neural crest cells have been shown to acquire some properties of chondrocytes (M ...
Sialic Acid Binding Domains of CD22 Are Required For Negative
Sialic Acid Binding Domains of CD22 Are Required For Negative

... (R130A and R137E), diminishes the negative regulatory function of CD22. This means that the ectodomains of CD22 are required for full function. We favor the hypothesis that this loss of function is directly due to the loss of binding to a sialic acid containing ligand. The R130 residue is highly con ...
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Cell encapsulation



Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.
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