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A C-terminus Mitochondrial-localization Region and BH3 Domain of
A C-terminus Mitochondrial-localization Region and BH3 Domain of

... for these functions is that unlike other modes of cell death, such as necrosis, apoptosis eliminates cells without eliciting an inflammatory response or causing damage to the surrounding tissue (Kerr et al. 1972). Disruption of the normal apoptotic process in animal models has been shown to cause si ...
Neuromodulation of Transduction and Signal
Neuromodulation of Transduction and Signal

... antagonists and 5HT-depleting agents were perfused through the lingual vasculature. Namely, when the 5HT content of taste buds was depleted, taste responses were hardly affected. Morimoto and Sato (1977) concluded that a 'catecholamine is a more likely candidate for a chemical neurotransmitter in fr ...
Reverse migration of neutrophils: Where, when, how and why
Reverse migration of neutrophils: Where, when, how and why

... dynamics of such responses is very much governed by the nature (e.g. pathogen or sterile injury) and magnitude of the inflammatory trigger [31,32,35-43]. In the above cited murine models of inflammation [35], the focus has been very much on swarm assembly and dynamics, with less emphasis being place ...
The consequences of Rad51 overexpression for normal and tumor
The consequences of Rad51 overexpression for normal and tumor

... [21–23]. Loss of the spnA gene results in a female sterile phenotype and DSB repair deficiency, but otherwise the mutants are viable. Ubiquitous overexpression of Rad51 using two different inducible promoter systems is lethal [24] and the deleterious effects of Rad51 overexpression are due to Rad51 b ...
237-747-1-SP - International Journal of Applied Research in
237-747-1-SP - International Journal of Applied Research in

... quite different than those of larger particles (Nalwa, 2005). ...


... (German Drug Law) fully GMP-conform. Furthermore, master and working cell banks have been GMP-conform established and stored, in order to later supply customers with series production. ...
Dictyostelium discoideum mutant synag 7 with altered G
Dictyostelium discoideum mutant synag 7 with altered G

... inhibition (Van Haastert et al. 1987). Inhibition of adenylate cyclase by GTP is blocked by pretreatment of cells with pertussis toxin (Van Haastert et al. 1987). Moreover, desensitization to persistent cyclic AMP stimuli is blocked after treatment with pertussis toxin in vivo (Snaar-Jagalska & Van ...
Budesonide and formoterol inhibit ICAM-1 and VCAM-1
Budesonide and formoterol inhibit ICAM-1 and VCAM-1

... ABSTRACT: The glucocorticoid budesonide and the long-acting b2-adrenoceptor agonist formoterol are used in asthma therapy for their anti-inflammatory and bronchodilating effects, respectively. Since expression of adhesion molecules on resident cells in the lung plays an important role in asthmatic i ...
PDF
PDF

... This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. ...
NanoTek™ Chitosan Product Sheet
NanoTek™ Chitosan Product Sheet

... much smaller molecular size than chitosan, and can absorb into the bloodstream. Both are derived from chitin, which is found in the exoskeletons of crustaceans such as shrimp, lobster or crab. Chitosan is an aminopolysaccharide that is chemically similar to cellulose. Chitosan oligosaccharides (CO) ...
A Cellular Hypothesis for the Induction of Blossom
A Cellular Hypothesis for the Induction of Blossom

... accelerated canopy transpiration (Gerard and Hipp, 1968; Paiva et al., 1998). As a cell expands, its plasma membrane and cell wall must increase in area. The incorporation of new material into the plasma membrane and cell wall is also a Ca2+dependent process and an elevated [Ca2+]cyt has been associ ...
DEFINING THE ROLE OF THE SHP2 PROTEIN TYROSINE
DEFINING THE ROLE OF THE SHP2 PROTEIN TYROSINE

... express mouse mast cell protease (mMCP) 1 and mMCP-2. Connective tissue mast cells stain positively with safranin as a result of heparin being contained within their granules, while they express mMCP-3, mMCP-4, mMCP-5 and mMCP-67,8. Stem Cell Factor (SCF) is the ligand for the Kit receptor and is th ...
Auxin and self-organization at the shoot apical
Auxin and self-organization at the shoot apical

... animals lies in the regulation of their organogenetic capacity over time. Unlike most animals, in which organogenesis occurs during embryonic development, plants can form new organs throughout their life cycle. Post-embryonic development occurs thanks to specialized tissues containing stem-cell nich ...
Self-assembled pH-responsive hyaluronic acid–g-poly(l
Self-assembled pH-responsive hyaluronic acid–g-poly(l

Chondroitin Sulphate: Antioxidant Properties and Beneficial Effects
Chondroitin Sulphate: Antioxidant Properties and Beneficial Effects

... Abstract: Most biological molecules exhibit more than one function. In particular, many molecules have the ability to directly/indirectly scavenge free radicals and thus act in living organisms as antioxidant. During oxidative stress, the increase of these molecules levels seems to be a biological r ...
Interaction of the endothelial nitric oxide synthase with the CAT
Interaction of the endothelial nitric oxide synthase with the CAT

... to eNOS in endothelial caveolae. Almost all of the evidence for the existence of an arginine paradox has come from in vivo studies. The dependence of eNOS on extracellular arginine has been much more difficult to demonstrate in vitro. For example, in the very first report that demonstrated that endo ...
iv Molecular Mechanisms of Notochord Vacuole
iv Molecular Mechanisms of Notochord Vacuole

... Figure 23. Notochord vacuoles are necessary for proper spine morphogenesis 77   Figure 24. Fragmented vacuoles leads to cells that are packed more densely, resulting in larvae that are shorter .......................................................................81   Figure 25. Proposed model o ...
Anti-HIV-1 activity of Trim 37
Anti-HIV-1 activity of Trim 37

Nanosilver—The burgeoning therapeutic molecule and its green
Nanosilver—The burgeoning therapeutic molecule and its green

... be a better method than the chemical methods due to the large amount of capital involved in production and it involves an energy intensive process. The use of hazardous chemicals such as hydrazine eliminates the method from being an eco-friendly one. Moreover nanocrystalline silver colloids produced ...
ABSTRACT
ABSTRACT

... Department of Cell Biology and Molecular Genetics ...
Cathepsin D released by lactating rat mammary epithelial cells is
Cathepsin D released by lactating rat mammary epithelial cells is

... Mammary tissues from lactating rats dissected free of connective and adipose tissues were cut into small fragments (1-2 mm3). Incubations were performed in Hanks’ medium plus sodium bicarbonate 0.2 g/l under an atmosphere of 95% O2 and 5% CO2. The pH of the Hanks’ medium after oxygenation was 7.5 an ...
INSULIN RESISTANCE IN H-35 RAT HEPATO~A CELLS IS
INSULIN RESISTANCE IN H-35 RAT HEPATO~A CELLS IS

... from 3 separate experiments. Open bars, control; hatched bars, ...
Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins
Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins

... Many Gram-negative pathogenic bacterial species, including Pseudomonas aeruginosa, produce vesicles that contain toxins or other virulence factors and, in several cases, vesicles have been proposed to be vehicles for toxin delivery to eukaryotic cells (14– 17). Significantly less is known about the r ...
Actin and Myosin Function in Directed Vacuole Movement during
Actin and Myosin Function in Directed Vacuole Movement during

Marine Origin Polysaccharides in Drug Delivery Systems
Marine Origin Polysaccharides in Drug Delivery Systems

... have M/G ratios of 1.16 and 1.82, respectively [30]. Alginate is biocompatible, has low toxicity and high bioavailability as well. These are the main advantages that make alginate one of the biopolymers with the widest biomedical applicability. One of the most common applications of alginate is thei ...
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Cell encapsulation



Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.
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