
Complex networks orchestrate epithelial–mesenchymal transitions
... Epithelial and mesenchymal cells differ in various functional and phenotypic characteristics (FIG. 1). Epithelial cells form layers of cells that are closely adjoined by specialized membrane structures, such as tight junctions, adherens junctions, desmosomes and gap junctions. In addition, epithelia ...
... Epithelial and mesenchymal cells differ in various functional and phenotypic characteristics (FIG. 1). Epithelial cells form layers of cells that are closely adjoined by specialized membrane structures, such as tight junctions, adherens junctions, desmosomes and gap junctions. In addition, epithelia ...
Sample pages 2 PDF
... epidermal keratinocytes. Moreover, membrane proteins such as α9β1 integrin which is a receptor for Extracellular Matrix (ECM) components involved in corneal epithelial cell adhesion and migration [69–71], shows a specific association with limbus and may contribute to the identification of corneal stem ...
... epidermal keratinocytes. Moreover, membrane proteins such as α9β1 integrin which is a receptor for Extracellular Matrix (ECM) components involved in corneal epithelial cell adhesion and migration [69–71], shows a specific association with limbus and may contribute to the identification of corneal stem ...
REVIEWS - Brandeis Life Sciences
... DOMINANT-NEGATIVE constructs, can be overexpressed by injecting RNA into the desired cells, resulting in spatially targeted gene mis-expression. Xenopus embryos are extremely receptive to experimental manipulation. Cells and tissues can be ablated or transplanted easily, and the techniques of experi ...
... DOMINANT-NEGATIVE constructs, can be overexpressed by injecting RNA into the desired cells, resulting in spatially targeted gene mis-expression. Xenopus embryos are extremely receptive to experimental manipulation. Cells and tissues can be ablated or transplanted easily, and the techniques of experi ...
Swimming behavior of the monotrichous bacterium Pseudomonas
... Pseudmonas fluorescens SBW25 exhibited a sophisticated swimming behavior unknown to any other bacteria. Figure 1a shows the trajectory of a free-swimming cell. It can swiftly adjust the direction when swimming forward (runs) without retardation on speed. This behavior has been called ‘turns’ by Harw ...
... Pseudmonas fluorescens SBW25 exhibited a sophisticated swimming behavior unknown to any other bacteria. Figure 1a shows the trajectory of a free-swimming cell. It can swiftly adjust the direction when swimming forward (runs) without retardation on speed. This behavior has been called ‘turns’ by Harw ...
Lipid raft–associated protein sorting in exosomes
... Exosomes were isolated by differential centrifugation as described previously.35 For further exosome purification, pellets were resuspended in 4 mL 2.55 M sucrose, 20 mM HEPES (N-2-hydroxyethylpiperazine-N⬘-2ethanesulfonic acid)/NaOH, pH 7.4. A linear sucrose gradient (2.25 to 0 M sucrose, 20 mM HEP ...
... Exosomes were isolated by differential centrifugation as described previously.35 For further exosome purification, pellets were resuspended in 4 mL 2.55 M sucrose, 20 mM HEPES (N-2-hydroxyethylpiperazine-N⬘-2ethanesulfonic acid)/NaOH, pH 7.4. A linear sucrose gradient (2.25 to 0 M sucrose, 20 mM HEP ...
Whole-cell biocatalysts by design - Microbial Cell Factories
... the synthesis of rhamnolipids from the cheap raw material butane using a tailored whole-cell biocatalyst. The AlkBGT system from Pseudomonas putida (for butane activation) and the RhlABC system from Pseudomonas aeruginosa (for rhamnolipid assembly) were integrated into the cell strain to result in r ...
... the synthesis of rhamnolipids from the cheap raw material butane using a tailored whole-cell biocatalyst. The AlkBGT system from Pseudomonas putida (for butane activation) and the RhlABC system from Pseudomonas aeruginosa (for rhamnolipid assembly) were integrated into the cell strain to result in r ...
Cancer-Initiating Cells from Colorectal Cancer Patients Escape from
... properties along with their putative non-CIC autologous counterparts from human primary CRC tissues. These CICs have been shown to display “tumor-initiating/stemness” properties, including the expression of CIC-associated markers (e.g., CD44, CD24, ALDH-1, EpCAM, Lgr5), multipotency, and tumorigenic ...
... properties along with their putative non-CIC autologous counterparts from human primary CRC tissues. These CICs have been shown to display “tumor-initiating/stemness” properties, including the expression of CIC-associated markers (e.g., CD44, CD24, ALDH-1, EpCAM, Lgr5), multipotency, and tumorigenic ...
Every B3 Past Paper Question
... Put ticks ( ) in the boxes next to the two features that would be suitable for ...
... Put ticks ( ) in the boxes next to the two features that would be suitable for ...
TOR SIGNALLING IN BUGS, BRAIN AND BRAWN
... The processes of cell growth and cell division are usually coupled to give rise to cells of a specific size. There are certain exceptions, however, in which one process occurs independently of the other. For example, division without growth occurs during early development when embryonic cells divide ...
... The processes of cell growth and cell division are usually coupled to give rise to cells of a specific size. There are certain exceptions, however, in which one process occurs independently of the other. For example, division without growth occurs during early development when embryonic cells divide ...
Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel
... 2001; Leung and Lamond, 2002; Lamond and Spector, 2003). Although the fundamental processes of ribosome biogenesis are very similar in all eukaryotes, there are significant ...
... 2001; Leung and Lamond, 2002; Lamond and Spector, 2003). Although the fundamental processes of ribosome biogenesis are very similar in all eukaryotes, there are significant ...
Role of the ABC Transporter Ste6 in Cell Fusion during Yeast
... Strain LM23-3az was mutagenized with EMS (34, 38) with a survival rate of 32% and accumulation of ~0.1% red Ade- colonies. Five independent mutagenesis reactions were conducted, and ~68,700 colonies were screened (outlined in Fig. 1). Both sterile and partially sterile mutants were identified by rep ...
... Strain LM23-3az was mutagenized with EMS (34, 38) with a survival rate of 32% and accumulation of ~0.1% red Ade- colonies. Five independent mutagenesis reactions were conducted, and ~68,700 colonies were screened (outlined in Fig. 1). Both sterile and partially sterile mutants were identified by rep ...
protcell
... Application for administration order Administration order in relation to protected cell companies or cells Functions of administrator and effects of administration order Discharge and variation of administration order Remuneration of administrator PART V - RECEIVERSHIP ORDER ...
... Application for administration order Administration order in relation to protected cell companies or cells Functions of administrator and effects of administration order Discharge and variation of administration order Remuneration of administrator PART V - RECEIVERSHIP ORDER ...
PDF
... embryonic gonad. The niche cells can be unambiguously identified with multiple markers as early as the embryo-to-larval transition, and stem cells are recruited shortly thereafter (Le Bras and Van Doren, 2006; Sheng et al., 2009; Sinden et al., 2012). For this reason, the male gonad provides an idea ...
... embryonic gonad. The niche cells can be unambiguously identified with multiple markers as early as the embryo-to-larval transition, and stem cells are recruited shortly thereafter (Le Bras and Van Doren, 2006; Sheng et al., 2009; Sinden et al., 2012). For this reason, the male gonad provides an idea ...
PDF - Bezanilla Lab
... of actin-based structures responsible for diverse cellular processes. Because multicellular organisms contain large formin gene families, establishing the physiological functions of formin isoforms has been difficult. Using RNAi, we analyzed the function of all 9 formin genes within the moss Physcom ...
... of actin-based structures responsible for diverse cellular processes. Because multicellular organisms contain large formin gene families, establishing the physiological functions of formin isoforms has been difficult. Using RNAi, we analyzed the function of all 9 formin genes within the moss Physcom ...
In vivo single-RNA tracking shows that most tRNA diffuses freely in
... translation-independent subcellular localization of transcripts encoding for membrane and soluble proteins has been observed in bacteria (4). The subcellular RNA localization can be explored further through detection of individual RNA molecules and measurement of their heterogeneity, a challenge tha ...
... translation-independent subcellular localization of transcripts encoding for membrane and soluble proteins has been observed in bacteria (4). The subcellular RNA localization can be explored further through detection of individual RNA molecules and measurement of their heterogeneity, a challenge tha ...
Article - Archive ouverte UNIGE
... cells (Jahoda and Oliver, 1981) retain their capacity to stimulate hair growth (Jahoda et al. 1984; Home et al. 1986) distinguishes them as a culture system with particular relevance to known biological function. Other investigations have used cultured dermal components from human hair follicles (Me ...
... cells (Jahoda and Oliver, 1981) retain their capacity to stimulate hair growth (Jahoda et al. 1984; Home et al. 1986) distinguishes them as a culture system with particular relevance to known biological function. Other investigations have used cultured dermal components from human hair follicles (Me ...
Ultrastructure of Hyaline, Border, and Vacuole Cells in Chick Inner Ear
... contrast to the border cells. Microtubules extend into the neck regions of organ supporting cells and often appear to be associated with the microvilli complex. Microtubules, in contrast, are typically absent from apical regions of border cells and are not associated with border-cell microvilli. Lon ...
... contrast to the border cells. Microtubules extend into the neck regions of organ supporting cells and often appear to be associated with the microvilli complex. Microtubules, in contrast, are typically absent from apical regions of border cells and are not associated with border-cell microvilli. Lon ...
Extracellular matrix

In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).