2015 – PKc-theta is a novel sc35 splicing factor regulator in
... of immune responses, alternative splicing of pre-mRNA is an emerging theme in the regulation of T cell function (5, 6). Several T cell genes, such as CD44 and CD45, undergo alternative splicing to produce distinct protein isoforms (7, 8). Furthermore, antigenic stimulation alters the pattern of alte ...
... of immune responses, alternative splicing of pre-mRNA is an emerging theme in the regulation of T cell function (5, 6). Several T cell genes, such as CD44 and CD45, undergo alternative splicing to produce distinct protein isoforms (7, 8). Furthermore, antigenic stimulation alters the pattern of alte ...
Role of cholesterol in SNARE-mediated trafficking on intracellular
... The cell surface delivery of extracellular matrix (ECM) and integrins is fundamental for cell migration in wound healing and during cancer cell metastasis. This process is not only driven by several soluble NSF attachment protein (SNAP) receptor (SNARE) proteins, which are key players in vesicle tra ...
... The cell surface delivery of extracellular matrix (ECM) and integrins is fundamental for cell migration in wound healing and during cancer cell metastasis. This process is not only driven by several soluble NSF attachment protein (SNAP) receptor (SNARE) proteins, which are key players in vesicle tra ...
Cell Wall, Cytoskeleton, and Cell Expansion in Higher Plants
... Figure 1. The Schematic Diagram Highlights Some Aspects of the Architecture, Hormonal Regulation, and Integrity Sensing of the Cell Wall. (A) The polysaccharide composition of primary cell walls is mostly cellulose, xyloglucan, and pectin. Blue arrows highlight biomechanical hotspots in which XyG a ...
... Figure 1. The Schematic Diagram Highlights Some Aspects of the Architecture, Hormonal Regulation, and Integrity Sensing of the Cell Wall. (A) The polysaccharide composition of primary cell walls is mostly cellulose, xyloglucan, and pectin. Blue arrows highlight biomechanical hotspots in which XyG a ...
Effects of intestinal adaptation on insulin binding to villus cell
... Insulin affects the expression of brush border enzymes by villus cells in vitro and in vivo. Physiological (lactation) and surgical (jejunoileal bypass) models of hyper- and hypoplasia were established so that insulin receptor characteristics could be related to villus histology, expression of sucra ...
... Insulin affects the expression of brush border enzymes by villus cells in vitro and in vivo. Physiological (lactation) and surgical (jejunoileal bypass) models of hyper- and hypoplasia were established so that insulin receptor characteristics could be related to villus histology, expression of sucra ...
********* 1 - Botanik in Bonn
... Subcellular defects linked to Myosin XI function A. Fluorescent markers expressed in myosin XI knock-out mutants B. Tail overexpression in cells expressing various organelle markers ...
... Subcellular defects linked to Myosin XI function A. Fluorescent markers expressed in myosin XI knock-out mutants B. Tail overexpression in cells expressing various organelle markers ...
during T Lymphocyte Activation Coordinately Regulated by ERK
... Activation of a naive T cell is a highly energetic event, which requires a substantial increase in nutrient metabolism. Upon stimulation, T cells increase in size, rapidly proliferate, and differentiate, all of which lead to a high demand for energetic and biosynthetic precursors. Although amino aci ...
... Activation of a naive T cell is a highly energetic event, which requires a substantial increase in nutrient metabolism. Upon stimulation, T cells increase in size, rapidly proliferate, and differentiate, all of which lead to a high demand for energetic and biosynthetic precursors. Although amino aci ...
Hormonal regulation of stem cell maintenance in roots
... These centres with their surrounding initial cells form a ‘stem cell niche’. The initial cells eventually its effect on chromatin reconfiguration in Posidonia oceanica. DNA methylation level and pattern were analysed in differentiate into organs, various under plant tissues, to plant such as low lat ...
... These centres with their surrounding initial cells form a ‘stem cell niche’. The initial cells eventually its effect on chromatin reconfiguration in Posidonia oceanica. DNA methylation level and pattern were analysed in differentiate into organs, various under plant tissues, to plant such as low lat ...
Altered Cell Fate in LiCI-Treated Sea Urchin Embryos
... Both classical and modern studies have shown that exposure to lithium during the early stages of development causes cells to adopt a more vegetal fate, and at the molecular level, to express vegetal markers that they would not otherwise synthesize. Since End016 was found to be expressed exclusively ...
... Both classical and modern studies have shown that exposure to lithium during the early stages of development causes cells to adopt a more vegetal fate, and at the molecular level, to express vegetal markers that they would not otherwise synthesize. Since End016 was found to be expressed exclusively ...
A1982PM90100001
... reported assays of whole blood folate using L. casei or Streptococcus faeca/is but the results were not consistent or reproducible. It was clear, however, that most of the tolate in blood was in the red cells, but, unlike folate in serum, red cell folate was largely in a conjugated (polyglutamated) ...
... reported assays of whole blood folate using L. casei or Streptococcus faeca/is but the results were not consistent or reproducible. It was clear, however, that most of the tolate in blood was in the red cells, but, unlike folate in serum, red cell folate was largely in a conjugated (polyglutamated) ...
Development of definitive endoderm from embryonic
... based on findings from studies using model systems such as Xenopus and zebrafish that provide easy access to early embryonic stages of development at a time when lineage commitment decisions are taking place. By contrast, the mouse embryo is much less amenable to such experimental approaches because ...
... based on findings from studies using model systems such as Xenopus and zebrafish that provide easy access to early embryonic stages of development at a time when lineage commitment decisions are taking place. By contrast, the mouse embryo is much less amenable to such experimental approaches because ...
How to Study and Exploit microRNAs for Gene Therapy Bernhard Gentner, M.D.
... microRNA: an abundant class of non-coding RNA • >700 miRNA species known in human, most are highly conserved in mammals • negatively regulate HALF of ALL mRNA transcripts by • directing mRNA destruction • inhibiting translation • extent of regulation of single targets may seem minor (in general 2-3 ...
... microRNA: an abundant class of non-coding RNA • >700 miRNA species known in human, most are highly conserved in mammals • negatively regulate HALF of ALL mRNA transcripts by • directing mRNA destruction • inhibiting translation • extent of regulation of single targets may seem minor (in general 2-3 ...
Using monoclonal antibodies to label living root hairs: a novel tool
... the inclusion of a detergent (0.85 mM Triton-X100) in the labeling protocol and noted no discernable difference in labeling results. Control experiments also showed that the labeling was specific. Table 1 provides a summary of antibodies used and labeling results that were obtained for the following ...
... the inclusion of a detergent (0.85 mM Triton-X100) in the labeling protocol and noted no discernable difference in labeling results. Control experiments also showed that the labeling was specific. Table 1 provides a summary of antibodies used and labeling results that were obtained for the following ...
Transcripts of the npm-alk fusion gene in anaplastic large cell
... with the application of modem analytical techniques including immunohistochemistry, electron microscopy, and molecular analysis of T- and B-cell antigen receptor gene rearrangements. However, ALCL can still be confused with HD due to the presence of cells resembling Reed-Stemberg cells and an overla ...
... with the application of modem analytical techniques including immunohistochemistry, electron microscopy, and molecular analysis of T- and B-cell antigen receptor gene rearrangements. However, ALCL can still be confused with HD due to the presence of cells resembling Reed-Stemberg cells and an overla ...
6 Movement of Molecules Across Cell Membranes
... a low solubility in the lipid bilayer. Most of these substances are retained within cells and organelles because they cannot diffuse across the lipid barrier of membranes. Diffusion of Ions through Protein Channels Ions such as Na⫹, K⫹, Cl⫺, and Ca2⫹ diffuse across plasma membranes at rates that are ...
... a low solubility in the lipid bilayer. Most of these substances are retained within cells and organelles because they cannot diffuse across the lipid barrier of membranes. Diffusion of Ions through Protein Channels Ions such as Na⫹, K⫹, Cl⫺, and Ca2⫹ diffuse across plasma membranes at rates that are ...
Print
... interaction of endothelial cells with basement membrane components plays an important role in the maintenance of vessel wall integrity. During development, the basement membrane of endothelium provides distinct spatial and molecular information that influences endothelial cell proliferation, migrati ...
... interaction of endothelial cells with basement membrane components plays an important role in the maintenance of vessel wall integrity. During development, the basement membrane of endothelium provides distinct spatial and molecular information that influences endothelial cell proliferation, migrati ...
Evaluation of Different Solvent Types on the Extraction of
... al., 2014) and in (Chen et al., 2013) and further in (Taher et al., 2014), possess high disease resistance ability, high metabolites content and high biomass density (Roy and Pal, 2014). Compared to conventional farming, microalgal farming are characterized by a high productivity per unit area and t ...
... al., 2014) and in (Chen et al., 2013) and further in (Taher et al., 2014), possess high disease resistance ability, high metabolites content and high biomass density (Roy and Pal, 2014). Compared to conventional farming, microalgal farming are characterized by a high productivity per unit area and t ...
orofacial embryology lecture
... (meiosis I is completed as the egg primordium then stops) -fertilzation result in the combination of the haploid egg and sperm = diploid zygote -called an embryo once it begins to divide (within 24 hours) -division = mitosis ...
... (meiosis I is completed as the egg primordium then stops) -fertilzation result in the combination of the haploid egg and sperm = diploid zygote -called an embryo once it begins to divide (within 24 hours) -division = mitosis ...
1. Describe the steps of the scientific method. 2. Define the terms
... Polar molecules like water have partially charged atoms at their ends Hydrogen bonds form when partial opposite charges in different molecules attract each other The partially positive hydrogens of one water molecule are attracted to the partially negative oxygen on another ...
... Polar molecules like water have partially charged atoms at their ends Hydrogen bonds form when partial opposite charges in different molecules attract each other The partially positive hydrogens of one water molecule are attracted to the partially negative oxygen on another ...
Adhesion and Adhesives of Fungi and Oomycetes
... substratum because adherent germlings and hyphae are flattened on the bottom; in contrast, germlings and hyphae that have not developed attached to a substratum are round in cross section (Epstein et al. 1987). Some fungi have contact-induced responses, and these generally require firm attachment. R ...
... substratum because adherent germlings and hyphae are flattened on the bottom; in contrast, germlings and hyphae that have not developed attached to a substratum are round in cross section (Epstein et al. 1987). Some fungi have contact-induced responses, and these generally require firm attachment. R ...
Genetic analysis of seed coat development in Arabidopsis
... or following fertilization must signal the seed coat to develop coordinately with the other tissues. Two recent studies have used mutants to provide evidence for the influence of the endosperm on both the growth and the differentiation of the seed coat. The control of seed coat growth relative to th ...
... or following fertilization must signal the seed coat to develop coordinately with the other tissues. Two recent studies have used mutants to provide evidence for the influence of the endosperm on both the growth and the differentiation of the seed coat. The control of seed coat growth relative to th ...
Cytoplasmic sequestration of the tumor suppressor p53 by a heat
... protein) in the outer mitochondrial membrane subsequently resulting in non-transcriptionally activated apoptosis [29]. Overexpression of mortalin leads to permanent tethering of p53 protein in the cytoplasm [30,31], a phenomenon referred to as cytoplasmic sequestration in human and mouse cells. As a ...
... protein) in the outer mitochondrial membrane subsequently resulting in non-transcriptionally activated apoptosis [29]. Overexpression of mortalin leads to permanent tethering of p53 protein in the cytoplasm [30,31], a phenomenon referred to as cytoplasmic sequestration in human and mouse cells. As a ...
Modulating progenitor accumulation attenuates lung angiogenesis in a mouse model of asthma
... ABSTRACT: Asthmatic responses are associated with the lung homing of bone marrow (BM)derived progenitors implicated as effectors of disease pathology. Studies have shown that increases in lung extracted vascular endothelial progenitor cells (VEPCs) correlate with airway angiogenesis and declining lu ...
... ABSTRACT: Asthmatic responses are associated with the lung homing of bone marrow (BM)derived progenitors implicated as effectors of disease pathology. Studies have shown that increases in lung extracted vascular endothelial progenitor cells (VEPCs) correlate with airway angiogenesis and declining lu ...
Exploring glycoside hydrolase family 5 (GH5) enzymes
... linear β-1,4-linked glucan chain including 500-14,000 glucose units. Each chain is stabilized by intramolecular hydrogen bonds, and about 40 cellulose chains connect to each other by intermolecular hydrogen bonds between hydroxyl groups in overlapping parallel arrays to form the highly ordered cellu ...
... linear β-1,4-linked glucan chain including 500-14,000 glucose units. Each chain is stabilized by intramolecular hydrogen bonds, and about 40 cellulose chains connect to each other by intermolecular hydrogen bonds between hydroxyl groups in overlapping parallel arrays to form the highly ordered cellu ...
Lim, K et al Science 2015
... Upon resolution, local tissue-resident memory T cells normally provide protection during lethal secondary virus challenge (19, 20). The number of memory T cells in both the lung and trachea, but not lymphoid memory T cells, was significantly lower when neutrophils were depleted during the primary in ...
... Upon resolution, local tissue-resident memory T cells normally provide protection during lethal secondary virus challenge (19, 20). The number of memory T cells in both the lung and trachea, but not lymphoid memory T cells, was significantly lower when neutrophils were depleted during the primary in ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).