A novel microtubule-modulating noscapinoid
... P Karna1, PCG Rida2, V Pannu1, KK Gupta3, WB Dalton4, H Joshi2, VW Yang4, J Zhou5 and R Aneja*,1 ...
... P Karna1, PCG Rida2, V Pannu1, KK Gupta3, WB Dalton4, H Joshi2, VW Yang4, J Zhou5 and R Aneja*,1 ...
Electron Microscopic Observations on the Excretion of Cell
... virtue of the plasticity of the cellular membrane that substances which cannot diffuse through it may be incorporated by, for example, pinocytosis (Lewis, 1931; Palade, 1953) or may be excreted from the cells. Although there may exist several mechanisms for the excretion or secretion of cellular pro ...
... virtue of the plasticity of the cellular membrane that substances which cannot diffuse through it may be incorporated by, for example, pinocytosis (Lewis, 1931; Palade, 1953) or may be excreted from the cells. Although there may exist several mechanisms for the excretion or secretion of cellular pro ...
Intracellular catalysis of disulfide bond formation by the human
... Many secreted proteins contain disulfide bonds, which are required for their proper folding, function and stability. In eukaryotic cells disulfide bond formation usually occurs while the protein folds in the lumen of the ER (endoplasmic reticulum). While disulfide bonds can be formed spontaneously i ...
... Many secreted proteins contain disulfide bonds, which are required for their proper folding, function and stability. In eukaryotic cells disulfide bond formation usually occurs while the protein folds in the lumen of the ER (endoplasmic reticulum). While disulfide bonds can be formed spontaneously i ...
Thyroglobulin, the major and obligatory
... folding of the protein, only two phosphate residues were removed readily, which therefore appear to be exposed on the surface of the TG molecule. Enzymatic removal of carbohydrates with endoglycosidase H or with endoglycosidase D was used to test for the presence of phosphate residues on the differe ...
... folding of the protein, only two phosphate residues were removed readily, which therefore appear to be exposed on the surface of the TG molecule. Enzymatic removal of carbohydrates with endoglycosidase H or with endoglycosidase D was used to test for the presence of phosphate residues on the differe ...
Targeting of P-Selectin to Two Regulated Secretory Organelles in
... organelles (RSOs) varies with cell type (35). Some proteins are found in the membranes of both organelles, reflecting the common requirements of exocytotic machinery (5, 36). This raises the question of how such a biorganellar distribution is attained. The itinerary of such proteins must be complex, ...
... organelles (RSOs) varies with cell type (35). Some proteins are found in the membranes of both organelles, reflecting the common requirements of exocytotic machinery (5, 36). This raises the question of how such a biorganellar distribution is attained. The itinerary of such proteins must be complex, ...
Cell Proliferation Kinetics and Drug Sensitivity of
... that caused the onset of stationary phase. Viability of Cells in Exponential and Stationary Growth. The viability, as determined by cloning efficiency, is shown in Chart 2. Viability decreased the longer the cells stayed in stationary phase. In this experiment the cells reached sta tionary at about ...
... that caused the onset of stationary phase. Viability of Cells in Exponential and Stationary Growth. The viability, as determined by cloning efficiency, is shown in Chart 2. Viability decreased the longer the cells stayed in stationary phase. In this experiment the cells reached sta tionary at about ...
Epithelial Tissue 1. Simple Squamous Epithelium 1.1 Section No.： 4
... amorphous ground substance in which is embedded by cartilage cells (Chondrocytes) . Chondrocytes are located in matrix lacunae. In living tissue, the chondrocytes fill the lacunae completely, but sometimes small spaces appear in the lacunae since the cytoplasm of chondrocyte tends to shrink after fi ...
... amorphous ground substance in which is embedded by cartilage cells (Chondrocytes) . Chondrocytes are located in matrix lacunae. In living tissue, the chondrocytes fill the lacunae completely, but sometimes small spaces appear in the lacunae since the cytoplasm of chondrocyte tends to shrink after fi ...
CELL
... organelle found in a eukaryotic cell. • Spherical in shape - separated from the cytoplasm by a double nuclear membrane . • Contain nuclear pores that permit - nutrients, waste, and cellular information- to pass both into, and out of, the nucleus. • The nucleus is the "Control Center" - contains DNA ...
... organelle found in a eukaryotic cell. • Spherical in shape - separated from the cytoplasm by a double nuclear membrane . • Contain nuclear pores that permit - nutrients, waste, and cellular information- to pass both into, and out of, the nucleus. • The nucleus is the "Control Center" - contains DNA ...
Bellairs pm6.5 - The International Journal of Developmental Biology
... substratum cells migrated forming a halo. This useful fact had long been known to investigators studying cells in tissue culture, but Abercrombie’s genius lay in his exploitation of the technique. The cells that migrate out are known as fibroblasts, but typically, in his 1976 paper with Dunn and Hea ...
... substratum cells migrated forming a halo. This useful fact had long been known to investigators studying cells in tissue culture, but Abercrombie’s genius lay in his exploitation of the technique. The cells that migrate out are known as fibroblasts, but typically, in his 1976 paper with Dunn and Hea ...
Observations upon the Growing Points in Normal and
... at the poles of the cells, and smaller ones at the periphery, in the region of the crosswalls. In non-septate filaments produced by growth in the presence of urethane the peripheral granules were not present. This is in accordance with the belief that these are the growing-pointsassociated with the ...
... at the poles of the cells, and smaller ones at the periphery, in the region of the crosswalls. In non-septate filaments produced by growth in the presence of urethane the peripheral granules were not present. This is in accordance with the belief that these are the growing-pointsassociated with the ...
Motion of red blood cells in a capillary with an - AJP
... membrane curvature (ks) and its spatial derivatives are calculated on the basis of the updated shape, and the shape is then adjusted iteratively until the system of equations is satisfied within a prescribed tolerance. Steady-state solutions are obtained by imposing a steady driving pressure and fol ...
... membrane curvature (ks) and its spatial derivatives are calculated on the basis of the updated shape, and the shape is then adjusted iteratively until the system of equations is satisfied within a prescribed tolerance. Steady-state solutions are obtained by imposing a steady driving pressure and fol ...
Origin of muscle satellite cells in the Xenopus embryo
... quiescent in the adult. They are small cells lying beneath the basement membrane surrounding the multinucleate muscle fibers. Skeletal muscle does not show continuous cell turnover in the adult organism but following muscle damage satellite cells become reactivated. They are then released from the m ...
... quiescent in the adult. They are small cells lying beneath the basement membrane surrounding the multinucleate muscle fibers. Skeletal muscle does not show continuous cell turnover in the adult organism but following muscle damage satellite cells become reactivated. They are then released from the m ...
The Arabidopsis sku6-spiral1 gene encodes a plus end
... (I) and (J) Wild-type (I) and spr1-6 (J) plants growing in the greenhouse. In (J), note the two spr1-6 leaves (indicated by arrows) that are not laying flat because of right-handed twisted petioles; the top right leaf is sideways, whereas the bottom left leaf is upside down. (K) and (L) Wild-type (K ...
... (I) and (J) Wild-type (I) and spr1-6 (J) plants growing in the greenhouse. In (J), note the two spr1-6 leaves (indicated by arrows) that are not laying flat because of right-handed twisted petioles; the top right leaf is sideways, whereas the bottom left leaf is upside down. (K) and (L) Wild-type (K ...
- Wiley Online Library
... The discovery of bacterial cytoskeletal proteins, for example, the actin-like proteins MreB and ParM, the tubulinlike protein FtsZ, and the intermediate filament protein crescentin, reinforced the strong similarity between prokaryotes and eukaryotes, thus highlighting the importance of bacteria as a ...
... The discovery of bacterial cytoskeletal proteins, for example, the actin-like proteins MreB and ParM, the tubulinlike protein FtsZ, and the intermediate filament protein crescentin, reinforced the strong similarity between prokaryotes and eukaryotes, thus highlighting the importance of bacteria as a ...
Pulsatile Stretch Remodels Cell-to-Cell Communication in Cultured
... after only 1 hour and a further increase after 6 hours (Cx43 signal increased from 0.73 to 1.86 and 2.02% cell area, and N-cadherin signal increased from 1.21 to 2.11 and 2.74% cell area after 1 and 6 hours, respectively). This was paralleled by an increase in ⌰ from 27 to 35 cm/s after 1 hour and 3 ...
... after only 1 hour and a further increase after 6 hours (Cx43 signal increased from 0.73 to 1.86 and 2.02% cell area, and N-cadherin signal increased from 1.21 to 2.11 and 2.74% cell area after 1 and 6 hours, respectively). This was paralleled by an increase in ⌰ from 27 to 35 cm/s after 1 hour and 3 ...
HISTOLOGICAL AND SEM STUDIES ON ORGANOGENESIS IN
... (Guzzo et al., 2004), where green clusters of compact embryo-derived callus gradually developed an epidermis-like tissue. At early stages of kiwifruit shoot formation, structures differing in appearance were formed. Jeannin et al. (1998) described a variety of structures differentiated in culture of ...
... (Guzzo et al., 2004), where green clusters of compact embryo-derived callus gradually developed an epidermis-like tissue. At early stages of kiwifruit shoot formation, structures differing in appearance were formed. Jeannin et al. (1998) described a variety of structures differentiated in culture of ...
Gumbo JR and Cloete TE
... external environment that was nutrient limited. The mechanism of cyanobacterial lysis may involve changes in ultrastructure of Microcystis aeruginosa, possibly affecting energy sources and the photosynthetic system after exposure to bacteria. This may lead to the death of the cyanobacteria after exh ...
... external environment that was nutrient limited. The mechanism of cyanobacterial lysis may involve changes in ultrastructure of Microcystis aeruginosa, possibly affecting energy sources and the photosynthetic system after exposure to bacteria. This may lead to the death of the cyanobacteria after exh ...
AtLSG1-2 Regulates Leaf Growth by Affecting Cell Proliferation and
... checked the expression of those genes specifically expressed in proliferation stage (Beemster et al., 2005), which includes CYCA2;3, CYCA3;2, CDKB2;1, CYCB1;5, CYCB2;1, and CYCB2;4, etc. Most of these genes were highly expressed in atlsg1-2 mutant (Supplementary Table S1). While the cause and effect ...
... checked the expression of those genes specifically expressed in proliferation stage (Beemster et al., 2005), which includes CYCA2;3, CYCA3;2, CDKB2;1, CYCB1;5, CYCB2;1, and CYCB2;4, etc. Most of these genes were highly expressed in atlsg1-2 mutant (Supplementary Table S1). While the cause and effect ...
Developmental plasticity, cell fate specification and morphogenesis
... arise. The first experiments that involved tracking cells labelled with in vivo markers suggested that blastomeres are different from each other already at the 2-cell stage. By non-invasively labelling blastomeres or marking the zona pellucida after the first cleavage division, it was demonstrated t ...
... arise. The first experiments that involved tracking cells labelled with in vivo markers suggested that blastomeres are different from each other already at the 2-cell stage. By non-invasively labelling blastomeres or marking the zona pellucida after the first cleavage division, it was demonstrated t ...
Mudskipper gill MR cell ion-transport proteins
... animals to eliminate ammonia actively is probably associated with the branchial MR cells. In the present study, we investigate the possibility that the branchial epithelium is the site of active NH4+ elimination. Iontransport proteins involved in the active elimination of NH4+ are localized using an ...
... animals to eliminate ammonia actively is probably associated with the branchial MR cells. In the present study, we investigate the possibility that the branchial epithelium is the site of active NH4+ elimination. Iontransport proteins involved in the active elimination of NH4+ are localized using an ...
Cell movements during epiboly and gastrulation in
... separates the blastoderm and the uncleaved yolk cell. At this time blastoderm cells are motile (D. A. Kane, in preparation), but major rearrangements among them have not yet occurred. (B) 50%-epiboly stage, onset of gastrula period, 5.2 h. Epiboly is well underway, and the blastoderm has thinned to ...
... separates the blastoderm and the uncleaved yolk cell. At this time blastoderm cells are motile (D. A. Kane, in preparation), but major rearrangements among them have not yet occurred. (B) 50%-epiboly stage, onset of gastrula period, 5.2 h. Epiboly is well underway, and the blastoderm has thinned to ...
Caveolin-3 and SAP97 form a scaffolding protein complex that
... to hypothesize that SAP97 and Cav-3 form a scaffolding complex capable of recruiting Kv1.5 and regulating its function. We first carried out coimmunoprecipitation and pulldown experiments to test whether SAP97 and Cav-3 form a complex in the mouse heart. After SAP97 was immunoprecipitated from mouse ...
... to hypothesize that SAP97 and Cav-3 form a scaffolding complex capable of recruiting Kv1.5 and regulating its function. We first carried out coimmunoprecipitation and pulldown experiments to test whether SAP97 and Cav-3 form a complex in the mouse heart. After SAP97 was immunoprecipitated from mouse ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).