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JMS 68/1 pp. 087-094 FINAL - Oxford Academic
JMS 68/1 pp. 087-094 FINAL - Oxford Academic

... Bartolomaeus & Ax, 1992). Podocytes possess numerous basal processes between which ultrafiltration slits, bridged by fine diaphragms, provide a pathway for the primary filtrate. The basal lamina, underlying the slits, has been shown to be the functional ultrafilter (Andrews, 1981; Morse, 1987). In a ...
here
here

Chapter 5: Attachment and entry of viruses into cells 1. Overview of
Chapter 5: Attachment and entry of viruses into cells 1. Overview of

... Entry of naked viruses 1. Most of naked viruses irreversible attachment of the virion to the cell surface leads to endocytosis. 2. Plasma membrane “flows” around the virion > more receptors bind > virion is completely enclosed in membrane # pinches off as an ...
High-throughput knockout screen in Schizosaccharomyces pombe
High-throughput knockout screen in Schizosaccharomyces pombe

Stem cells are the hope of modern stomatology
Stem cells are the hope of modern stomatology

... tricalcium phosphate structure. After eight weeks from implantation, new bone tissue was found [30]. The periodontal stem cells niche is located in close proximity to blood vessels, and the cells found therein have properties characteristic for stem cells, such as small size and long cell division c ...
The Tobacco Homolog of Mammalian Calreticulin
The Tobacco Homolog of Mammalian Calreticulin

... to that of the well-characterized ER chaperones BiP and endoplasmin. However, expression patterns in response to different stress conditions as well as tissue-specific expression patterns indicate that these genes are differentially regulated and may not act in concert. ...
Myc Requires Distinct E2F Activities to Induce S Phase
Myc Requires Distinct E2F Activities to Induce S Phase

... induction of E2F2 and E2F3 by Myc could be direct, since a series of Myc binding sites are essential for this induction as well as for the normal induction of E2F2 and E2F3 expression following serum stimulation (Sears et al., 1997; Adams et al., 2000). The fact that Myc and E2F genes share function ...
II-Expressing Microvesicles at Their Surface Follicular Dendritic
II-Expressing Microvesicles at Their Surface Follicular Dendritic

... carry MHC class II molecules at their surface and to be capable of specifically stimulating CD4-positive T cells in vitro. The released internal vesicles of MIICs have been called exosomes (16), a term that was introduced for exocytosed vesicles in reticulocytes (17). Exocytosis of MIICs or multives ...
Mechanics and Modeling of Plant Cell Growth
Mechanics and Modeling of Plant Cell Growth

... a model that predicts strain-hardening and loosening of the cell wall material can explain a number of experimental observations [23]. Conceptually, the basic molecular model consists of cellulose microfibrils oriented perpendicular to the long axis and tethered to each other by threads of hemicellu ...
Practice General
Practice General

... Electron micrograph of the basal lamina. The portion of the basal lamina referred to as the lamina densa (1) is a thin gray line lying just outside the cell membrane. Reticular fibers (2) are associated with the lamina densa. Notice here that the basal lamina surrounds an epithelial cell. Two odd po ...
Chemical–Biological Studies of Subcellular Organization in Bacteria
Chemical–Biological Studies of Subcellular Organization in Bacteria

The Cellular Mechanism of Epithelial Rearrangement during
The Cellular Mechanism of Epithelial Rearrangement during

... elegans embryo, in which two rows of epithelial cells rearrange in a morphogenetic process known as dorsal intercalation. The intercalating cells extend basal protrusions which squeeze between their opposing neighbors beneath their adherens junctions. As the intercalating cells move forward, these p ...
BIOLOGY I MIDTERM OBJECTIVES Chapter 1 (The Nature of
BIOLOGY I MIDTERM OBJECTIVES Chapter 1 (The Nature of

... both types of growth 5) Explain the concept of carrying capacity and describe its significance to any population 6) Explain how age structure diagrams can predict the future growth rate of a population. 7) Explain the three parts of the definition of biodiversity and explain its importance (both to ...
figure 1 - Philosophical Transactions of the Royal Society B
figure 1 - Philosophical Transactions of the Royal Society B

... Figure 1. Cell structure divergence in phagotrophic non-amoeboid flagellates provided the basis for evolving animals, fungi, plants and chromists. Pseudopodia evolved secondarily, myosin II providing the basis for pseudopodia in animals, Amoebozoa (and Percolozoa) and muscles. Chloroplasts, originat ...
Is the Cytoskeleton Necessary for Viral Replication?
Is the Cytoskeleton Necessary for Viral Replication?

... have been characterized in detail, it is assumed that all viruses need the actin and/or microtubule networks to actively transport new viruses into the cell, their macromolecular components to appropriate places throughout the cell, and their progeny out. Most studies to date have described specific ...
glycosphingolipid degradation - Limes-Institut-Bonn
glycosphingolipid degradation - Limes-Institut-Bonn

... as a ‘liftase’, recognizing GM2 within the membrane and, by binding to it, lifting the lipid out of the bilayer and presenting it to the water-soluble B-hexosaminidase A for degradation (Fig. 3, mode 1). However, it is also possible that the activator-lipid complex leaves the membrane and the enzyma ...
Growth-induced Microcracking and Repair Mechanisms of Fruit
Growth-induced Microcracking and Repair Mechanisms of Fruit

... Freeze-dried samples were removed and, under a stereo-microscope, affixed to a 12 mm aluminum stub using double-sided carbon tape by pressing only on opposite edges of the tissue using a stainless steel microprobe. The stub was placed in a glass vacuum desiccator containing packaged silica gel and k ...
SepF, a novel FtsZ-interacting protein required for a late step in cell
SepF, a novel FtsZ-interacting protein required for a late step in cell

... in transport, and it has been speculated that FtsW translocates the lipid-linked precursor for the septal peptidoglycan matrix (Holtje, 1998). The periplasmic part of the divisome comprises, aside from Pbp2B, three other conserved cell division proteins: FtsL, DivIB and DivIC. Like Pbp2B, these prot ...
PDF
PDF

Cortical cell fate specification
Cortical cell fate specification

... influence the differentiation of cortical cells, they did not reveal whether these signals act upon dividing progenitor cells or upon newly postmitotic cells. To specifically examine the influence of the cortical environment on dividing progenitor cells, we labeled dividing cells by adding Bromodeox ...
Document
Document

... devastating congenital intestinal disorder that results in severe nutrient deprivation. Further analysis revealed that Cdc42-deficient stem cells had cell division defects, reduced capacity for clonal expansion and differentiation into Paneth cells, and increased apoptosis. Cdc42 deficiency impaired ...
The origin of the eukaryotic cell: A genomic investigation
The origin of the eukaryotic cell: A genomic investigation

... would have been enormously greater than occurs in DNA-based systems’’ (12). This solution to the paradox implies that if the actin and FtsA (tubulin and FtsZ) did have a common ancestor, then it was not to be found in either in Archaea or Bacteria, but in some hypothetical RNA-based ‘‘urkaryote,’’ o ...
Origin of Cancer: An Information, Energy, and Matter Disease
Origin of Cancer: An Information, Energy, and Matter Disease

Ch 9 modified
Ch 9 modified

... • Key Concepts (1): – The Golgi apparatus is organized into discrete compartments called cisternae. The cisternae are stacked on top of one another, and are classified as cis, medial, or trans according to their relative location within the overall Golgi structure. – Golgi-resident proteins are prim ...
Quantification of gap junction selectivity
Quantification of gap junction selectivity

... To understand why the mammalian genome includes 20 or more connexin genes, the functional differences between the gap junctions that they form must be appreciated. Since their discovery, much has been learned about gap junctions in a broad sense, but their functional and regulatory differences are s ...
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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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