Differentiation of Mesenchymal Stem Cells Into Dopaminergic
... Key words: Mesenchymal stem cells (MSCs); Dopaminergic neuron-like cells (DA neuron-like cells); Differentiate ...
... Key words: Mesenchymal stem cells (MSCs); Dopaminergic neuron-like cells (DA neuron-like cells); Differentiate ...
One tissue, two fates: different roles of megagametophyte cells
... abies (L.) Karst], a type II metacaspase, mcII-Pa, is required for the burst of the caspase activity that occurs in the cells undergoing PCD (Suarez et al., 2004). The ability to self-destruct in response to environmental changes and cell signalling is shared by animal and plant cells, which indicat ...
... abies (L.) Karst], a type II metacaspase, mcII-Pa, is required for the burst of the caspase activity that occurs in the cells undergoing PCD (Suarez et al., 2004). The ability to self-destruct in response to environmental changes and cell signalling is shared by animal and plant cells, which indicat ...
Adult haematopoietic stem cells lacking Hif-1α self
... Finally, we set out to delete Hif-1α more broadly from the BM using Mx1-Cre, which in addition to haematopoietic cells, also recombines in the BM microenvironment13. Hif-1αfl/fl;Mx1-Cre and control mice received 6 doses of pIpC and were analysed 30 days after the last injection (Suppl. Fig. 4A). pIp ...
... Finally, we set out to delete Hif-1α more broadly from the BM using Mx1-Cre, which in addition to haematopoietic cells, also recombines in the BM microenvironment13. Hif-1αfl/fl;Mx1-Cre and control mice received 6 doses of pIpC and were analysed 30 days after the last injection (Suppl. Fig. 4A). pIp ...
Lymphatic and Immune System
... ● defend against various viruses and cancer cells ● secretes “cell-cutting” substances called perforins ● perforins lyse cell membrane, destroying infected cell ● secrete chemicals that enhance inflammation ...
... ● defend against various viruses and cancer cells ● secretes “cell-cutting” substances called perforins ● perforins lyse cell membrane, destroying infected cell ● secrete chemicals that enhance inflammation ...
PDF
... times of 43-90 min; if we assume, in the absence of information specific to the opossum, that its duration of mitosis is also of the order of 1 h, then the number of divisions at stage 28 may be adequate to account for the rates of increase in cell numbers, which are of the order of 5 %/h, and would ...
... times of 43-90 min; if we assume, in the absence of information specific to the opossum, that its duration of mitosis is also of the order of 1 h, then the number of divisions at stage 28 may be adequate to account for the rates of increase in cell numbers, which are of the order of 5 %/h, and would ...
Clostridium sordellii Lethal-Toxin Autoprocessing and
... and gastrointestinal infections in livestock. One of the principle virulence factors is TcsL, a large protein toxin which glucosylates host GTPases to cause cytopathic and cytotoxic effects. TcsL has two enzymatic domains, an N-terminal glucosyltransferase domain (GTD) and an autoprocessing domain r ...
... and gastrointestinal infections in livestock. One of the principle virulence factors is TcsL, a large protein toxin which glucosylates host GTPases to cause cytopathic and cytotoxic effects. TcsL has two enzymatic domains, an N-terminal glucosyltransferase domain (GTD) and an autoprocessing domain r ...
The development of dorsal root ganglia and ventral horns in the
... times of 43-90 min; if we assume, in the absence of information specific to the opossum, that its duration of mitosis is also of the order of 1 h, then the number of divisions at stage 28 may be adequate to account for the rates of increase in cell numbers, which are of the order of 5 %/h, and would ...
... times of 43-90 min; if we assume, in the absence of information specific to the opossum, that its duration of mitosis is also of the order of 1 h, then the number of divisions at stage 28 may be adequate to account for the rates of increase in cell numbers, which are of the order of 5 %/h, and would ...
IDENTIFICATION OF CD133+/NESTIN+ PUTATIVE CANCER STEM
... Key words: CD133/Nestin/Non-small cell lung cancer (NSCLC)/Cancer stem cell (CSC)/Immunofluorescence Aims. No effective treatment for lung cancer exists currently. One reason for this, is the development of drug resistance, assumed to be associated with cancer stem cell (CSCs) emergence within the t ...
... Key words: CD133/Nestin/Non-small cell lung cancer (NSCLC)/Cancer stem cell (CSC)/Immunofluorescence Aims. No effective treatment for lung cancer exists currently. One reason for this, is the development of drug resistance, assumed to be associated with cancer stem cell (CSCs) emergence within the t ...
Interplay between cell growth and cell cycle in
... cell volume is occupied mostly by cytoplasmic growth and increased nuclear volume associated with DNA replication, whereas in more differentiated tissues the increased volume can result mostly from water uptake and vacuole enlargement. Controlled cell-wall relaxation is made possible by the structur ...
... cell volume is occupied mostly by cytoplasmic growth and increased nuclear volume associated with DNA replication, whereas in more differentiated tissues the increased volume can result mostly from water uptake and vacuole enlargement. Controlled cell-wall relaxation is made possible by the structur ...
Characterization of Dependencies Between Growth and
... Statistical modeling provides a powerful and principled foundation for characterizing these correlations in lineages of proliferating cells. Indeed, correlation and biological lineage analysis have been intertwined since the development of the correlation coefficient by Galton and Pearson for data o ...
... Statistical modeling provides a powerful and principled foundation for characterizing these correlations in lineages of proliferating cells. Indeed, correlation and biological lineage analysis have been intertwined since the development of the correlation coefficient by Galton and Pearson for data o ...
1 A generalized quantitative antibody homeostasis model
... Starting with the expression of the surrogate light chain B cells go through several cycles of activation, proliferation, survival, and antibody production, all governed by BCR engagement. The generalized quantitative model (GQM) assumes that in order to deliver functional signals to the B cells the ...
... Starting with the expression of the surrogate light chain B cells go through several cycles of activation, proliferation, survival, and antibody production, all governed by BCR engagement. The generalized quantitative model (GQM) assumes that in order to deliver functional signals to the B cells the ...
Mechanisms of cell rearrangement and cell
... Terminal filaments develop successively along the anterior-posterior and medial-lateral axis At onset of metamorphosis all TFs (around 20) have differentiated, each of them a stack of 8-9 aligned disc-shaped cells that are oriented along the anterior-posterior axis of the ovary. The stacks are arran ...
... Terminal filaments develop successively along the anterior-posterior and medial-lateral axis At onset of metamorphosis all TFs (around 20) have differentiated, each of them a stack of 8-9 aligned disc-shaped cells that are oriented along the anterior-posterior axis of the ovary. The stacks are arran ...
Cellular Internalization of Fluorescent Proteins via Arginine
... of plant cells to serve as a screening barrier for transport of materials across the biomembranes. Only specific biomolecules and ions may pass through via specific transporters or protein channels. Therefore, highly basic and hydrophilic AID peptides should not pass through the membranes. In fact, ...
... of plant cells to serve as a screening barrier for transport of materials across the biomembranes. Only specific biomolecules and ions may pass through via specific transporters or protein channels. Therefore, highly basic and hydrophilic AID peptides should not pass through the membranes. In fact, ...
Stabilization Proliferative Potential and Telomere Length Increased
... mAbs used for surface staining were all purchased from BD Biosciences (San Diego, CA). To surface stain cells, Abs were added for 15 min at room temperature, after which the cells were washed in PBS, fixed in 2% paraformaldehyde, and stored at 4°C until acquisition on a FACSCalibur. For staining wit ...
... mAbs used for surface staining were all purchased from BD Biosciences (San Diego, CA). To surface stain cells, Abs were added for 15 min at room temperature, after which the cells were washed in PBS, fixed in 2% paraformaldehyde, and stored at 4°C until acquisition on a FACSCalibur. For staining wit ...
![[Frontiers in Bioscience, 5, d50-57, January 1, 2000] THE CONTROL](http://s1.studyres.com/store/data/017171575_1-70635603f98612e3c5ac310e8691f919-300x300.png)
[Frontiers in Bioscience, 5, d50-57, January 1, 2000] THE CONTROL
... multisubunit complex that promotes the proteosomemediated proteolysis of key regulators of mitosis. However, very little is known about the functions of the individual APC/C components and how the function of these components is regulated. Is the activity of the APC/C an all-or-nothing mechanism ? I ...
... multisubunit complex that promotes the proteosomemediated proteolysis of key regulators of mitosis. However, very little is known about the functions of the individual APC/C components and how the function of these components is regulated. Is the activity of the APC/C an all-or-nothing mechanism ? I ...
Links between apoptosis, proliferation and the cell cycle (PDF
... Many physiological processes, including proper tissue development and homeostasis, require a balance between apoptosis and cell proliferation. All somatic cells proliferate via a mitotic process determined by progression through the cell cycle. Apoptosis (programmed cell death) occurs in a wide vari ...
... Many physiological processes, including proper tissue development and homeostasis, require a balance between apoptosis and cell proliferation. All somatic cells proliferate via a mitotic process determined by progression through the cell cycle. Apoptosis (programmed cell death) occurs in a wide vari ...
Sample Chapter
... membrane proteins can be classified according to their shapes. One group of proteins, for example, consists of tightly coiled, rodlike molecules embedded in the phospholipid bilayer. Some such fibrous proteins completely span the membrane; that is, they extend outward from its surface on one end, wh ...
... membrane proteins can be classified according to their shapes. One group of proteins, for example, consists of tightly coiled, rodlike molecules embedded in the phospholipid bilayer. Some such fibrous proteins completely span the membrane; that is, they extend outward from its surface on one end, wh ...
Plant Cell
... Much of what is understood about mitosis in plants is based on extrapolation from how cell division functions in other systems, such as yeast (Scheres and Benfey, 1999). Identification of new genes that control this multicellular process in plants is hampered by the lack of a system in which cell di ...
... Much of what is understood about mitosis in plants is based on extrapolation from how cell division functions in other systems, such as yeast (Scheres and Benfey, 1999). Identification of new genes that control this multicellular process in plants is hampered by the lack of a system in which cell di ...
ANISOTROPIC EXPANSION OF THE PLANT CELL WALL
... flat solar panels of leaves to the coiled grappling hooks of tendrils. Thompson (1917) realized that adaptive advantage is insufficient to explain form; he argued that additionally the process of construction plays a role. The only construction process used to shape plant organs is expansion of cell w ...
... flat solar panels of leaves to the coiled grappling hooks of tendrils. Thompson (1917) realized that adaptive advantage is insufficient to explain form; he argued that additionally the process of construction plays a role. The only construction process used to shape plant organs is expansion of cell w ...
Tolerance of Immobilized Yeast Cells in Imidazolium
... ILs possess a certain degree of biocompatibility. The tolerance of yeast cells to the ILs decreases with the increase of the R chain length of these ILs. The experiment indicated that 1-butyl-3-methylimidazolium hexafluorophosphate ([BMim][PF6]) possessed excellent biocompatibility compared to the o ...
... ILs possess a certain degree of biocompatibility. The tolerance of yeast cells to the ILs decreases with the increase of the R chain length of these ILs. The experiment indicated that 1-butyl-3-methylimidazolium hexafluorophosphate ([BMim][PF6]) possessed excellent biocompatibility compared to the o ...
Calcium: a regulation system emerges in plant cells
... In order that changes in cytosolic calcium levels can regulate cellular processes the level of the ion itself must be closely regulated. Indirectly we know that cells must efficiently hold cytosolic calcium well below the cytotoxic concentration found in the extracellular fluid, 10~ 3 M (Hepler & Wa ...
... In order that changes in cytosolic calcium levels can regulate cellular processes the level of the ion itself must be closely regulated. Indirectly we know that cells must efficiently hold cytosolic calcium well below the cytotoxic concentration found in the extracellular fluid, 10~ 3 M (Hepler & Wa ...
Involvement of the Vacuoles of the Endodermis in
... Most importantly, in both transgenic plants all amyloplasts in the endodermis sedimented in the direction of gravity, similar to the wild-type plant. In addition, the shape of the endodermal cells also recovered (Figures 2C and 2D). These results indicate that the expression of SGR2 and ZIG in the e ...
... Most importantly, in both transgenic plants all amyloplasts in the endodermis sedimented in the direction of gravity, similar to the wild-type plant. In addition, the shape of the endodermal cells also recovered (Figures 2C and 2D). These results indicate that the expression of SGR2 and ZIG in the e ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).