Expression of the Catalytic and Regulatory Subunits of Protein
... membrane or nuclear fraction was unaltered (data not shown), thereby suggesting that the translocation of phosphatase from the cytosol fraction to membrane or nuclear fractions did not occur. PP2A is inhibited completely by S n@tOKA, while PP1 is hardly affected at this concentration and complete in ...
... membrane or nuclear fraction was unaltered (data not shown), thereby suggesting that the translocation of phosphatase from the cytosol fraction to membrane or nuclear fractions did not occur. PP2A is inhibited completely by S n@tOKA, while PP1 is hardly affected at this concentration and complete in ...
Degenerins - Tavernarakis Lab
... strengthens the argument that degenerin channels function directly in mechanotransduction rather than merely serving to maintain the osmotic environment so that other channels can function. As is true for the MEC-4 and MEC-10 touch receptor channels, the model of UNC-8 and DEL-1 function that is bas ...
... strengthens the argument that degenerin channels function directly in mechanotransduction rather than merely serving to maintain the osmotic environment so that other channels can function. As is true for the MEC-4 and MEC-10 touch receptor channels, the model of UNC-8 and DEL-1 function that is bas ...
Clinical Implications of Intestinal Stem Cell Markers in Colorectal
... Lgr5 expressing cells are proposed to mark actively cycling stem cells exerting a homeostatic role in the small intestine of mice.18 Furthermore, spheroid cultures derived from human primary tumors are enriched for LGR5 expression, and the receptor has been suggested to be a selective cancer stem ce ...
... Lgr5 expressing cells are proposed to mark actively cycling stem cells exerting a homeostatic role in the small intestine of mice.18 Furthermore, spheroid cultures derived from human primary tumors are enriched for LGR5 expression, and the receptor has been suggested to be a selective cancer stem ce ...
Embryonic origin and fate of chondroid tissue and
... various skeletal tissues involved in the development of 9th day of incubation, the primordia of dentary, anguthe avian skull. Primary cartilage (PC) is intensively lar, surangular, and opercular bones consist of chonstained by toluidine blue and obviously differs from droid tissue, obviously deposit ...
... various skeletal tissues involved in the development of 9th day of incubation, the primordia of dentary, anguthe avian skull. Primary cartilage (PC) is intensively lar, surangular, and opercular bones consist of chonstained by toluidine blue and obviously differs from droid tissue, obviously deposit ...
PDF
... embryos used for counting progeny of opq′, the contribution of micromere opq′ was inferred by comparing the pattern of cells arising from cell OPQ with that arising from cell OPQ′′, using the subtractive method of Zackson (1982). For this purpose, the OPQ blastomere was injected with TRDA and the OP ...
... embryos used for counting progeny of opq′, the contribution of micromere opq′ was inferred by comparing the pattern of cells arising from cell OPQ with that arising from cell OPQ′′, using the subtractive method of Zackson (1982). For this purpose, the OPQ blastomere was injected with TRDA and the OP ...
multiple functions The ADAMs family of metalloproteases
... 2001). Adamalysins are similar to the matrixins in their metalloprotease domains, but contain a unique integrin receptor-binding disintegrin domain (Fig. 1). It is the presence of these two domains that give the ADAMs their name (a disintegrin and metalloprotease). The domain structure of the ADAMs ...
... 2001). Adamalysins are similar to the matrixins in their metalloprotease domains, but contain a unique integrin receptor-binding disintegrin domain (Fig. 1). It is the presence of these two domains that give the ADAMs their name (a disintegrin and metalloprotease). The domain structure of the ADAMs ...
Expression of Nuclear Lamin A and Muscle
... muscle-specific genes are developmentally and coordinately regulated (Paterson and Bishop, 1977; Devlin and Emerson, 1978, 1979; Affara et al., 1980; Endo and Nadal-Ginard, 1987), suggesting the existence of regulatory mechanisms common to the expression of many muscle-specific genes. At the present ...
... muscle-specific genes are developmentally and coordinately regulated (Paterson and Bishop, 1977; Devlin and Emerson, 1978, 1979; Affara et al., 1980; Endo and Nadal-Ginard, 1987), suggesting the existence of regulatory mechanisms common to the expression of many muscle-specific genes. At the present ...
TR Worksheets
... Tracheids transport water and mineral ions. They are long, thin tubes with overlapping cells. They have pits in the walls so water can pass through from one tracheid to another. 5. List the two main types of cells of which phloem tissue is composed. Sieve cells and companion cells 6. Describe how th ...
... Tracheids transport water and mineral ions. They are long, thin tubes with overlapping cells. They have pits in the walls so water can pass through from one tracheid to another. 5. List the two main types of cells of which phloem tissue is composed. Sieve cells and companion cells 6. Describe how th ...
Control of Mitotic Events by Nap1 and the Gin4 Kinase
... coordinated by two large families of proteins called cyclins and cyclin-dependent kinases (for reviews see King et al., 1994; Murray and Hunt, 1993; Norbury and Nurse, 1992). The cyclins appear at specific times during the cell cycle to bind and activate cyclin-dependent kinases, thereby inducing ce ...
... coordinated by two large families of proteins called cyclins and cyclin-dependent kinases (for reviews see King et al., 1994; Murray and Hunt, 1993; Norbury and Nurse, 1992). The cyclins appear at specific times during the cell cycle to bind and activate cyclin-dependent kinases, thereby inducing ce ...
Cell Wall Polysaccharides are Mislocalized to the Vacuole in
... et al. 2011, Drakakaki et al. 2012). Recently, two YPT/RAB-interacting proteins (YIPs), YIP4a and YIP4b, have been identified as ECH interactors, implying that ECH/YIP4a/YIP4b may recruit RABs for post-Golgi vesicle targeting (Gendre et al. 2013). In echidna and yip4a yip4b mutants, Golgi function i ...
... et al. 2011, Drakakaki et al. 2012). Recently, two YPT/RAB-interacting proteins (YIPs), YIP4a and YIP4b, have been identified as ECH interactors, implying that ECH/YIP4a/YIP4b may recruit RABs for post-Golgi vesicle targeting (Gendre et al. 2013). In echidna and yip4a yip4b mutants, Golgi function i ...
Nance et al gastrulation paper - The Hardin Lab
... spaces between cells are indicated by arrowheads. (D,E) Membrane contacts at the same, high magnification showing examples of (D) a small space (arrow) between lateral surfaces and (E) a large space associated with basal surfaces; arrows in E illustrate close apposition of membranes around the space ...
... spaces between cells are indicated by arrowheads. (D,E) Membrane contacts at the same, high magnification showing examples of (D) a small space (arrow) between lateral surfaces and (E) a large space associated with basal surfaces; arrows in E illustrate close apposition of membranes around the space ...
Perk Is Essential for Translational Regulation and Cell Survival
... strong evidence that the ability to attenuate translation in response to ER stress plays an important role in mitigating the consequences of this insult to cellular homeostasis. These experiments also support an essential role for Perk in this adaptation and suggest that Perk deficiency may have a s ...
... strong evidence that the ability to attenuate translation in response to ER stress plays an important role in mitigating the consequences of this insult to cellular homeostasis. These experiments also support an essential role for Perk in this adaptation and suggest that Perk deficiency may have a s ...
Dynamic in vivo interactions among Myc network members
... distinct roles for the encoded proteins in tissue-speci®c negative control of cellular proliferation (Foley et al., 1998; Schreiber-Agus et al., 1998). Despite the well-described interactions of Myc network proteins, little is known about their distribution within the nucleus, or how they seek out o ...
... distinct roles for the encoded proteins in tissue-speci®c negative control of cellular proliferation (Foley et al., 1998; Schreiber-Agus et al., 1998). Despite the well-described interactions of Myc network proteins, little is known about their distribution within the nucleus, or how they seek out o ...
Reduction in drug-induced DNA double-strand
... topoisomerase (topo) II inhibitors.1,2 The mechanisms of resistance associated with 1-mediated adhesion are unknown. It is thought that DNA cross-linking agents and topo II inhibitors initiate cellular death by inducing DNA damage. Thus, cellular adhesion by means of 1 integrins could confer resis ...
... topoisomerase (topo) II inhibitors.1,2 The mechanisms of resistance associated with 1-mediated adhesion are unknown. It is thought that DNA cross-linking agents and topo II inhibitors initiate cellular death by inducing DNA damage. Thus, cellular adhesion by means of 1 integrins could confer resis ...
vilnius university
... deficits in the number of functional cells that can contribute to the development and progression of heart failure. Consequently, the transplantation of skeletal myoblasts or various origin stem cells or cardiomyocytes derived from them into the injured myocardium is a novel and promising approach i ...
... deficits in the number of functional cells that can contribute to the development and progression of heart failure. Consequently, the transplantation of skeletal myoblasts or various origin stem cells or cardiomyocytes derived from them into the injured myocardium is a novel and promising approach i ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).