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Imprinting in the endosperm: a possible role in preventing wide
Imprinting in the endosperm: a possible role in preventing wide

... placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. Imprinted genes are characterized by their uniparental expression, the other parental allele being silenced. Normal development of the endosperm thus requires a highly specific balance of gene expression ...
Understanding Tools and Techniques in Protein Structure Prediction
Understanding Tools and Techniques in Protein Structure Prediction

Metabolism of Xenobiotics
Metabolism of Xenobiotics

... 8.1. Nomenclature of Cytochromes P450 "The nomenclature system is based solely on the sequence similarity among P450s and does not indicate the properties or function of individual P450s" In the current nomenclature system [ ], the cytochrome "P450s are named using the root symbol CYP ..., followed ...
Chpt10_TxnRNAPol.doc
Chpt10_TxnRNAPol.doc

... a. The general transcription factors (GTFs) are proteins required for accurate and efficient transcription that are not subunits of purified RNA polymerase. We will focus primarily on the general transcription initiation factors (GTIFs), which are proteins needed for accurate initiation of transcrip ...
The Amino Acid Sequences of the Myelin
The Amino Acid Sequences of the Myelin

Volume 16 - Number 1 January 2012 Atlas of Genetics and Cytogenetics
Volume 16 - Number 1 January 2012 Atlas of Genetics and Cytogenetics

... in early stages of the disease but cell growth became androgen-independent. ADAM10 have been found to be expressed in all prostate tumor samples (Karan et al., 2003). Interestingly, McCulloch et al. have observed that ADAM10 expression was up-regulated by androgen stimulation. Those observations wer ...
Role of two-component systems in the virulence of Streptococcus
Role of two-component systems in the virulence of Streptococcus

... membrane-associated sensor histidine kinase (HK) and a cytoplasmic cognate response regulator (RR). Upon receipt of a specific external stimulus the kinase domain of the HK sensor protein is activated to autophosphorylate a conserved histidine residue. HK proteins tend to be found as homodimers that ...
PCB Biodegradation and bphA1 Gene Expression Induced by
PCB Biodegradation and bphA1 Gene Expression Induced by

CHAPTER ONE: INTRODUCTION AND LITERATURE REVIEW  1.1
CHAPTER ONE: INTRODUCTION AND LITERATURE REVIEW 1.1

MENDEL`S PRINCIPLES
MENDEL`S PRINCIPLES

... traits from parent to offspring. Some historical controversy exists as to whether these botanists actually rediscovered Mendel’s rules by their own research or whether their research led them to Mendel’s original paper. In any case, all three made important contributions to the early stages of genet ...
Erythroid Iron Metabolism
Erythroid Iron Metabolism

... The hemoglobin molecule is uniquely suited for the transport of oxygen from the lungs to peripheral tissues without oxidation of its heme1 (a complex of protoporphyrin IX with ferrous iron) groups and to facilitate the return of carbon dioxide from the tissues back to the lungs [6, 7]. In adult huma ...
proteins
proteins

... • game, octopus, lobster (low digestibility) ...
Novel Ciliate Genetic Code Variants Including the Reassignment of
Novel Ciliate Genetic Code Variants Including the Reassignment of

... We provide evidence suggesting that the functions of these codons in C. magnum depend on their location within mRNA. They are decoded as amino acids at internal positions, but specify translation termination when in close proximity to an mRNA 30 end. The frequency of stop codons in protein coding se ...
2012-06-14-EBI-plant-bioinf-course
2012-06-14-EBI-plant-bioinf-course

... – SE Quantification against known genes – PE Novel transcripts, transcript level quantification ...
MOLECULAR BIOLOGY OF FRUIT MATURATION AND
MOLECULAR BIOLOGY OF FRUIT MATURATION AND

Bioethics Thesaurus for Genetics
Bioethics Thesaurus for Genetics

... The Classification field (CL) indicates what number, or combination of numbers, from the Bioethics Research Library’s Classification Scheme would have been assigned to the document. (“+” after a number indicates that a searcher might find any number starting with 15. that appears on the Classificati ...
Fundamentals of Genetics
Fundamentals of Genetics

... For example, there are two possible outcomes of a coin flip: The coin may land either heads up or tails up. The chance, or probability, of either outcome is equal. Therefore, the probability that a single coin flip will land heads up is 1 chance in 2. This amounts to 1/2, or 50 percent If you flip a ...
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink

... Thus, breeding of resistant cultivars is a desirable means of minimizing crop losses, especially when they are incorporated into systems of integrated control (see Diederichsen and others, this issue; Faggian and Strelkov, this issue; Donald and Porter, this issue). Sources of resistance have been i ...
Mendelian Genetics
Mendelian Genetics

... separated by the centromere *The smaller arm is designated ‘p ‘ and the larger arm is desinated ‘q’ *Numbered regions and subregions are then assigned from the centromere outward (1 is closest to the centromere) ...
The population dynamics during evolution under
The population dynamics during evolution under

... comparing the evolved strains’ and parent strains’ data. Only the perfect match (PM) data from the resulting CEL files were used for analysis. Probes that span repeated regions or transposable elements were filtered out. Normalization factors were computed for each chromosome by averaging the signal ...
No Slide Title
No Slide Title

... Adenosine Deaminase defects ...
The “One-Bead-One-Compound” Combinatorial Library Method
The “One-Bead-One-Compound” Combinatorial Library Method

... regarded as one of the most important recent advances in medicinal chemistry. In addition, it is also an extremely powerful tool in basic research. Combinatorial library methods were first applied to peptides2-5 and oligonucleotides.6-12 Since then, the field has been expanded to include proteins,13 ...
Topic 13: Meiosis
Topic 13: Meiosis

... chromosomes (tetrads), instead of individual replicated chromosomes ...
3-A Notes
3-A Notes

... separated by the centromere *The smaller arm is designated ‘p ‘ and the larger arm is desinated ‘q’ *Numbered regions and subregions are then assigned from the centromere outward (1 is closest to the centromere) ...
Evolution and Natural Selection Lab.rtf
Evolution and Natural Selection Lab.rtf

< 1 ... 76 77 78 79 80 81 82 83 84 ... 2254 >

Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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