redundancy and regulatory interactions between two
... (AF052570), suggesting a possible role for this sequence in the negative regulation of C-function gene expression (Figure 1B). Two types of FAR cDNA were identified in the cDNA library at different frequencies. The DNA sequence and predicted amino acid-coding potential of the rarer of the two cDNAs ...
... (AF052570), suggesting a possible role for this sequence in the negative regulation of C-function gene expression (Figure 1B). Two types of FAR cDNA were identified in the cDNA library at different frequencies. The DNA sequence and predicted amino acid-coding potential of the rarer of the two cDNAs ...
the list of 56 genes that the American College of Medical Genetics and Genomics
... here as incidental findings, the analysis may not be technically equivalent to examining these genes as a primary finding. For example, clinical sequencing could have areas of diminished or absent coverage in the genes examined for incidental findings that would be filled in by Sanger sequencing or ...
... here as incidental findings, the analysis may not be technically equivalent to examining these genes as a primary finding. For example, clinical sequencing could have areas of diminished or absent coverage in the genes examined for incidental findings that would be filled in by Sanger sequencing or ...
SALIVARY GLAND CHROMOSOMES IN THE TWO RACES OF
... and BOCHE1933), the behavior in salivary gland cells suggests that one of the arms contains more inert material than the other. In most salivary gland preparations, there is no indication that the two arms of the X chromosome belong together, but occasionally, on crushing the nucleus, they are separ ...
... and BOCHE1933), the behavior in salivary gland cells suggests that one of the arms contains more inert material than the other. In most salivary gland preparations, there is no indication that the two arms of the X chromosome belong together, but occasionally, on crushing the nucleus, they are separ ...
Bio-session package - Social Science Genetic Association Consortium
... pronounced ‘‘snip,’’ stands for single nucleotide polymorphism.) These projects, called genome-wide association studies, each cost around $10 million or more. The results of this costly international exercise have been disappointing. About 2,000 sites on the human genome have been statistically link ...
... pronounced ‘‘snip,’’ stands for single nucleotide polymorphism.) These projects, called genome-wide association studies, each cost around $10 million or more. The results of this costly international exercise have been disappointing. About 2,000 sites on the human genome have been statistically link ...
The Role of Six1 in the Genesis of Muscle Cell and Skeletal Muscle
... that the SD is necessary to specific binding to protein partners and that the specificity in partner selection is crucial to the role of each protein [35]. Most recently, Six1 was shown to predominantly use a single helix to interact with EYA, and the mutation of a single amino acid in the helices o ...
... that the SD is necessary to specific binding to protein partners and that the specificity in partner selection is crucial to the role of each protein [35]. Most recently, Six1 was shown to predominantly use a single helix to interact with EYA, and the mutation of a single amino acid in the helices o ...
Transcript Isoform Differences Across Human Tissues Are
... Important biological processes are regulated by the expression of alternative isoforms 8,9 , and their mis-regulation has been observed in many diseases, including cancer 10,11,12,13 . For dozens of genes, it has been experimentally demonstrated that alternative isoforms result in proteins with diff ...
... Important biological processes are regulated by the expression of alternative isoforms 8,9 , and their mis-regulation has been observed in many diseases, including cancer 10,11,12,13 . For dozens of genes, it has been experimentally demonstrated that alternative isoforms result in proteins with diff ...
Directionality in FLP Protein-promoted Site
... containing the change of interest. All plasmids were purified from FIG. 1. Sequence of the yeast 2 p plasmid DNA within which the strain HBlOl (11)by banding twice in CsC1 gradients in the recombination occurs. The 13-base pair repeats are shaded. Cleav- presence of ethidium bromide. The sequence of ...
... containing the change of interest. All plasmids were purified from FIG. 1. Sequence of the yeast 2 p plasmid DNA within which the strain HBlOl (11)by banding twice in CsC1 gradients in the recombination occurs. The 13-base pair repeats are shaded. Cleav- presence of ethidium bromide. The sequence of ...
The Wnt code: cnidarians signal the way
... level. Besides in situ hybridization (ISH) protocols and the full set of the genomic tools (BAC, EST and cDNA libraries) RNAi, morpholinos, transient and stable transfection are available or under optimization procedure. The introduction of transgenic approaches to the field of cnidarian biology was ...
... level. Besides in situ hybridization (ISH) protocols and the full set of the genomic tools (BAC, EST and cDNA libraries) RNAi, morpholinos, transient and stable transfection are available or under optimization procedure. The introduction of transgenic approaches to the field of cnidarian biology was ...
Lactococcus lactis as expression host for the biosynthetic
... quantum yield (Q) are highly sensitive parameters for monitoring changes in the structure and dynamics of a protein. In numerous studies, the intrinsic protein fluorescence was used to monitor processes like enzyme kinetics, protein–ligand interactions or protein (un)folding. Modern molecular biolog ...
... quantum yield (Q) are highly sensitive parameters for monitoring changes in the structure and dynamics of a protein. In numerous studies, the intrinsic protein fluorescence was used to monitor processes like enzyme kinetics, protein–ligand interactions or protein (un)folding. Modern molecular biolog ...
Within- and between-species DNA sequence variation and the
... Extensive DNA data emerging from genome-sequencing projects have revitalized interest in the mechanisms of molecular evolution. Although the contribution of natural selection at the molecular level has been debated for over 30 years, the relevant data and appropriate statistical methods to address t ...
... Extensive DNA data emerging from genome-sequencing projects have revitalized interest in the mechanisms of molecular evolution. Although the contribution of natural selection at the molecular level has been debated for over 30 years, the relevant data and appropriate statistical methods to address t ...
Evolution of hard proteins in the sauropsid integument in relation to
... Hard skin appendages in amniotes comprise scales, feathers and hairs. The cell organization of these appendages probably derived from the localization of specialized areas of dermal–epidermal interaction in the integument. The horny scales and the other derivatives were formed from large areas of de ...
... Hard skin appendages in amniotes comprise scales, feathers and hairs. The cell organization of these appendages probably derived from the localization of specialized areas of dermal–epidermal interaction in the integument. The horny scales and the other derivatives were formed from large areas of de ...
In Memoriam: Jacques Monod (1910–1976)
... In 1953, Jacques Monod was made head of a new department (fig. 4), called Cellular Biochemistry and at about the same time Francxois Jacob and Elie Wollman, in Lwoff’s laboratory, elucidated the mechanisms of bacterial conjugation and gene transfer, thus providing new and powerful tools to attack th ...
... In 1953, Jacques Monod was made head of a new department (fig. 4), called Cellular Biochemistry and at about the same time Francxois Jacob and Elie Wollman, in Lwoff’s laboratory, elucidated the mechanisms of bacterial conjugation and gene transfer, thus providing new and powerful tools to attack th ...
PDF
... RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila Weili Cai, Xiaomin Bao, Huai Deng, Ye Jin, Jack Girton, Jørgen Johansen and Kristen M. Johansen* JIL-1 is the major kinase controlling the phosphorylation state of histone H3S10 at in ...
... RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila Weili Cai, Xiaomin Bao, Huai Deng, Ye Jin, Jack Girton, Jørgen Johansen and Kristen M. Johansen* JIL-1 is the major kinase controlling the phosphorylation state of histone H3S10 at in ...
C-terminal Truncation of p21H Preserves Crucial Kinetic and
... either at position 12/13 or 59/61 (for reviews see Refs. 1-3). The p21 protein products of the Ha-, K-, and N-ras genes have identical amino acid sequences for the first 80 amino acids and aremore than 85%identical up to amino acids 1641 165. The C-terminal25amino acids are very divergent, except fo ...
... either at position 12/13 or 59/61 (for reviews see Refs. 1-3). The p21 protein products of the Ha-, K-, and N-ras genes have identical amino acid sequences for the first 80 amino acids and aremore than 85%identical up to amino acids 1641 165. The C-terminal25amino acids are very divergent, except fo ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
... 1998; Reuman et al. 1999). It is presumably possible for changes to occur in the localization of membrane proteins. However, the elaborate membrane structures present in some algae, particularly those with secondary plastids, implies that such changes do not occur very easily. Thus, the location of ...
... 1998; Reuman et al. 1999). It is presumably possible for changes to occur in the localization of membrane proteins. However, the elaborate membrane structures present in some algae, particularly those with secondary plastids, implies that such changes do not occur very easily. Thus, the location of ...
- NRC Research Press
... synteny with the distal one-third end of the long arm of rice chromosome 3. In between those conserved regions, there is a region on the long arm of the Group 5 chromosomes which shows broken synteny. The proximal part of the short arms of the Group 5 chromosomes showed conserved synteny with a segm ...
... synteny with the distal one-third end of the long arm of rice chromosome 3. In between those conserved regions, there is a region on the long arm of the Group 5 chromosomes which shows broken synteny. The proximal part of the short arms of the Group 5 chromosomes showed conserved synteny with a segm ...
Міністерство охорони здоров`я України Харківський
... atom of the carboxylic acid carbon chain. The general structural formula of an αamino acid is: O C OH H2N ...
... atom of the carboxylic acid carbon chain. The general structural formula of an αamino acid is: O C OH H2N ...
The novel Cer-like protein Caronte mediates the establishment of
... An important factor in this regard is Lefty-1, another transforming growth factor-b (TGF-b) family member, that has been proposed to act as a molecular midline barrier that would con®ne and prevent the `X' factor from diffusing from the left to the right side of the embryo12,13. Here we show that an ...
... An important factor in this regard is Lefty-1, another transforming growth factor-b (TGF-b) family member, that has been proposed to act as a molecular midline barrier that would con®ne and prevent the `X' factor from diffusing from the left to the right side of the embryo12,13. Here we show that an ...
The enhancement of ribosomal transcription by the recycling of RNA
... pX1108c in the same orientation as the wild type terminator, (pXUGlc), a second with two terminators inserted tandemly in this orientation, (pXHG2c) and a third with the terminator inserted into, pXl^ESlc in the corresponding position but the opposite orientation, (pXUGllc). Each construct was micro ...
... pX1108c in the same orientation as the wild type terminator, (pXUGlc), a second with two terminators inserted tandemly in this orientation, (pXHG2c) and a third with the terminator inserted into, pXl^ESlc in the corresponding position but the opposite orientation, (pXUGllc). Each construct was micro ...
A gain of function mutation causing skeletal overgrowth in the
... (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critical region. All five genes are located on the same strand. Marker positions are shown along with their number of crossovers from rapunzel (see Supplemental data for more details rega ...
... (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critical region. All five genes are located on the same strand. Marker positions are shown along with their number of crossovers from rapunzel (see Supplemental data for more details rega ...