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Characterization of Dependencies Between Growth and
Characterization of Dependencies Between Growth and

... to cell division commitment. Beyond this point, cells are presumed to complete S/G2 /M at similar rates and in a size-independent manner. As such, studies of dependence between growth and division have focused on G1 . Moreover, coordination between growth and division has commonly been analyzed with ...
Developing a `thick skin`: a paradoxical role for
Developing a `thick skin`: a paradoxical role for

The Growing Outer Epidermal Wall: Design and
The Growing Outer Epidermal Wall: Design and

... a major role in restricting the rate of organ expansion. In accordance with Savaldi-Goldstein et al. (2007), it was concluded that hormonal signals may be exchanged between the epidermal and internal tissues that co-ordinate the growth process of the multicellular system. This ‘tissue interaction mo ...
Divergent mechanisms underlie Smad4
Divergent mechanisms underlie Smad4

... moderate overexpression of Smad4 (roughly threefold of "normal" endogenous levels in Smad4-positive Paca44 cells, Fig. 1A) displayed strong TGFβ responsiveness in transient transfection assays with p3Tplux (5–6 fold induction) and p6SBE (40 fold induction) promoter reporter constructs (Fig. 1B). Sma ...
The Expression of an Extensin-Like Protein
The Expression of an Extensin-Like Protein

... and Glu. Comparison with both Dif10 and Dif54 extensin-like proteins revealed that specifically spaced repetitive elements contribute to the sequence similarity rather than identity across a large region of LeExt1 that is similar with the compared proteins (Fig. 2). These elements are characterized ...
Pseudolaric Acid B Induced Cell Cycle Arrest, Au
Pseudolaric Acid B Induced Cell Cycle Arrest, Au

Apoptotic cell removal
Apoptotic cell removal

... [32,33]. Alterations to surface charge on apoptotic cells were also attributed to carbohydrate moieties [32,34] although specific sugars on the apoptotic cell surface were not identified in either of these studies. On the other hand there is some evidence for increased expression of mannose on apopt ...
Human granulocyte-macrophage colony
Human granulocyte-macrophage colony

... Natural GM-CSF has O-linked glycosylation sites at amino acid residues 22, 24, 26 and 27 and N-linked glycosylation sites at amino acid residues 44 and 5437. Interestingly, it was observed that glycosylation is not required for biological activity of the protein and the removal of carbohydrates actu ...
Evidence for inducible recruitment of Wiskott
Evidence for inducible recruitment of Wiskott

... family GTPase Cdc42.30 Thus, it has been suggested that the recruitment of WASp to the plasma membranes is mediated by the SLP-76 protein.14 In addition, molecular imaging analysis also reveals the co-localization of WASp with TCR-associated protein tyrosine kinase ZAP-70 (ζ-chain-associated protein ...
Facultad de Ciencias Tráfico de células dendríticas a través
Facultad de Ciencias Tráfico de células dendríticas a través

... lymph nodes. Up to 50% of the protein that extravasates from blood vessels cannot be directly reabsorbed by these capillaries and has to be taken back to blood through the lymphatic network (Pepper and Skobe, 2003). This vascular system was first documented by ancient Greeks. Hipocrates described ly ...
Plant Molecular Biology
Plant Molecular Biology

... 1 and 2B). A very low percentage (less than 2%) of structure-less ghosts and cellular debris that are typical for necrotic cell death were also observed after 24 h DEX treatment (data not shown). However, even after 36 or 48 h treatment, the majority of cells belonged to categories x, y and z (Figur ...
The role of P2 receptors in controlling infections by intracellular
The role of P2 receptors in controlling infections by intracellular

... by M. tuberculosis The first evidence for an involvement of ATPe in the control of intracellular infections came from the laboratory of Kaplan, who demonstrated in 1994, that ATPe-mediated apoptosis in Mycobacterium tuberculosis-infected macrophages is associated with the inhibition of mycobacterial ...
PD-1 promotes immune exhaustion by inducing antiviral T cell
PD-1 promotes immune exhaustion by inducing antiviral T cell

... ginal zone macrophages (MZM), myeloid DCs (mDCs), and red pulp macrophages—all populations that reside in the splenic red pulp or marginal zone. We confirmed this immuno­ histochemically by examining PD-L1 expression on splenic frozen sections (Fig. 2 C). The splenic distribution of PD-L1 in Arm-inf ...
as a PDF
as a PDF

Dataset for histopathology reporting of mucosal malignancies of the
Dataset for histopathology reporting of mucosal malignancies of the

... Certain features of invasive mucosal carcinomas (type, size and grade of the primary carcinoma, the pattern of invasion and proximity of carcinoma to resection margins) have been shown to be related to clinical outcome.3-13 ...
A single mutation in the core domain of the lac repressor reduces
A single mutation in the core domain of the lac repressor reduces

... GalR/LacI family (PurR [42]) and might play a role in LacI as well (see ONPF binding in [PDB:1EFA], Figure 1B). We investigated this hypothesis by substituting the large and bulky tryptophan residue at position 220 with all 20 amino acids. We built a reporter system in which the green fluorescent pr ...
immunohistological study of mannan polysaccharides in poplar stem
immunohistological study of mannan polysaccharides in poplar stem

... Mannan polysaccharides serve as storage reserves in seeds and as structure elements in cell walls, but they may also perform other important functions during plant growth. As one of the major hemicelluloses in angiosperm wood, little is known about the presence and localization of mannan polysacchar ...
An autocrine Wnt5a-Ror signaling loop mediates sympathetic target
An autocrine Wnt5a-Ror signaling loop mediates sympathetic target

... PCR analyses on sympathetic ganglia and target tissues i.e. the salivary glands and heart tissue revealed no differences in Wnt5a transcript levels between Wnt5afl/fl and wild-type animals (Supplementary Fig. 1). In order to delete Wnt5a in sympathetic neurons, we crossed mice homozygous for the floxed ...
Gibberellins accumulate in the elongating endodermal cells of
Gibberellins accumulate in the elongating endodermal cells of

... germination, root and shoot elongation, flowering and fruit patterning (7–9). Over the years, more than 130 GAs have been identified, of which only a few, such as GA1, GA3, and GA4, are bioactive (8). Much progress has been made in understanding how plants control GA response through regulation of bio ...
Plk4/SAK/ZYG-1 in the regulation of centriole
Plk4/SAK/ZYG-1 in the regulation of centriole

... and is required for normal duplication [24,25,27,28]. Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, ...
Prostaglandins as modulators of immunity
Prostaglandins as modulators of immunity

... of EP3 (α, β and γ) are coupled primarily to Gi and are most often inhibitory to cAMP. (There is some evidence that additional signaling cascades might be activated by EP3 binding.) Abbreviations: AC, adenylate cyclase; DAG, diacylglycerol; IP3, inositol triphosphate; PIP2, phosphatidylinositol diph ...
Female Gametophyte Development in Flowering Plants
Female Gametophyte Development in Flowering Plants

... maize (64). MSP1 encodes a leucine-rich repeat containing receptor-like kinase (LRRRLK). This implies that signaling between the archesporial cell and its neighboring cells is controlled by a ligand-receptor signaling cascade, and this plays a critical role in female germline development. These findi ...
Mediation of Clathrin-Dependent Trafficking during
Mediation of Clathrin-Dependent Trafficking during

... loss-of-function scd1-2 plants also display defects in overall growth and development; they are stunted in both aerial structures and roots, are infertile (Falbel et al., 2003), and have increased bacterial pathogen resistance (Korasick et al., 2010) compared with the wild type. The predicted 131.5- ...
Microtubule Associated Protein 1b (MAP1B) Is a Marker of the
Microtubule Associated Protein 1b (MAP1B) Is a Marker of the

... PP2A, respectively [12–18]. Homozygous constitutive MAP1B knockout mice displayed striking developmental defects in the brain, including the absence of the corpus callosum, a reduced number of large myelinated axons and myelinization defects in peripheral nerves [16]. However these mice displayed on ...
Sarcolemmal cholesterol and caveolin-3 dependence of - AJP
Sarcolemmal cholesterol and caveolin-3 dependence of - AJP

... Downloaded from http://ajpheart.physiology.org/ by 10.220.33.2 on June 18, 2017 ...
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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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