Session 241 Ganglion Cells: Development, axotomy, trauma
... Northwestern University, Evanston, IL. Purpose: In addition to rod and cone photoreceptors of the outer retina, intrinsically photosensitive retinal ganglion cells (ipRGCs) constitute a third class of inner retinal photoreceptors that play roles in both image and non-image forming vision. ipRGCs exp ...
... Northwestern University, Evanston, IL. Purpose: In addition to rod and cone photoreceptors of the outer retina, intrinsically photosensitive retinal ganglion cells (ipRGCs) constitute a third class of inner retinal photoreceptors that play roles in both image and non-image forming vision. ipRGCs exp ...
Mice lacking the homeodomain transcription factor
... homeobox gene family have restricted expression in the pancreatic islet: Nkx2.2 mRNA is present in the adult pancreatic islets and in pancreatic α and β cell lines; and Nkx6.1 is expressed in adult β cells, and in α and β cell lines (Rudnick et al., 1994; Jensen et al., 1996). In an attempt to under ...
... homeobox gene family have restricted expression in the pancreatic islet: Nkx2.2 mRNA is present in the adult pancreatic islets and in pancreatic α and β cell lines; and Nkx6.1 is expressed in adult β cells, and in α and β cell lines (Rudnick et al., 1994; Jensen et al., 1996). In an attempt to under ...
MECHANISMS OF PATTERN FORMATION IN PLANT
... of the zygote, which are precisely controlled in many organisms, give rise to a population of cells, different from one another and from their progenitors, that will form the body plan of the embryo. The process by which cells are specified in three dimensions has been termed pattern formation. Mech ...
... of the zygote, which are precisely controlled in many organisms, give rise to a population of cells, different from one another and from their progenitors, that will form the body plan of the embryo. The process by which cells are specified in three dimensions has been termed pattern formation. Mech ...
Plasmodesmata-Mediated Cell-to-Cell Communication in the Shoot
... (sRNAs) act as mobile signals that are actively and selectively transported to target cells through PD to specify their fates [18]. Around twenty years ago, the first mobile signal moving between cells via PD, the homeodomain (HD) TF KNOTTED1 (KN1), was discovered in maize. KN1 is expressed in the L ...
... (sRNAs) act as mobile signals that are actively and selectively transported to target cells through PD to specify their fates [18]. Around twenty years ago, the first mobile signal moving between cells via PD, the homeodomain (HD) TF KNOTTED1 (KN1), was discovered in maize. KN1 is expressed in the L ...
Subset-Specific Reductions in Lung Lymphocyte
... Preliminary studies indicated that 95–100% of the CD45⫹ cells in the light scatter gate expressed the CD4, CD8, CD19, ␥␦ TCR, or Gr-1 epitopes. Gr-1 (also known as Ly-6G) is expressed by murine neutrophils and eosinophils; consequently, the positive cells in the lymphocyte gate using this flow cytom ...
... Preliminary studies indicated that 95–100% of the CD45⫹ cells in the light scatter gate expressed the CD4, CD8, CD19, ␥␦ TCR, or Gr-1 epitopes. Gr-1 (also known as Ly-6G) is expressed by murine neutrophils and eosinophils; consequently, the positive cells in the lymphocyte gate using this flow cytom ...
Expression of Nuclear Lamin A and Muscle
... lamins (i.e., lamins A and C) are suggested to directly or indirectly bind chromatin, and by assembling with B type lamins (Georgatos et al., 1988), associate chromatin with the nuclear envelope (Lebkowski and Laemmli, 1982; Gerace et al., 1984; Burke and Gerace, 1986; Benavente and Krohne, ...
... lamins (i.e., lamins A and C) are suggested to directly or indirectly bind chromatin, and by assembling with B type lamins (Georgatos et al., 1988), associate chromatin with the nuclear envelope (Lebkowski and Laemmli, 1982; Gerace et al., 1984; Burke and Gerace, 1986; Benavente and Krohne, ...
PHYSIOLOGICAL AND CHEMICAL CHARACTERISTICS OF
... unpublished data). This sensitivity to pH seems to be one of the regulators of antibacterial activity. The concentration and composition of electrolytes as well as the pH are regulated by a variety of ion pumps and channels that maintain conditions maximizing the antimicrobial activity. A similar re ...
... unpublished data). This sensitivity to pH seems to be one of the regulators of antibacterial activity. The concentration and composition of electrolytes as well as the pH are regulated by a variety of ion pumps and channels that maintain conditions maximizing the antimicrobial activity. A similar re ...
REVIEW ARTICLE Mechanisms of pattern formation in development
... formation of morphological structures, such as the limb and the tail, involving ‘progress zone’ growth (Duboule, 1995). Experimental evidence for this mechanism is still limited, but in vertebrates it has been shown that expression of genes involved in somitogenesis exhibit oscillatory behavior (Mar ...
... formation of morphological structures, such as the limb and the tail, involving ‘progress zone’ growth (Duboule, 1995). Experimental evidence for this mechanism is still limited, but in vertebrates it has been shown that expression of genes involved in somitogenesis exhibit oscillatory behavior (Mar ...
Expression of the Catalytic and Regulatory Subunits of Protein
... therapy in inducing high remission rates in patients with acute pro myelocytic leukemia (3, 4). The biological effects of ATRA appear to be mediated through a number of closely related nuclear retinoic acid receptors that possess discrete DNA-binding and retinoic acid-binding domains (5). Although t ...
... therapy in inducing high remission rates in patients with acute pro myelocytic leukemia (3, 4). The biological effects of ATRA appear to be mediated through a number of closely related nuclear retinoic acid receptors that possess discrete DNA-binding and retinoic acid-binding domains (5). Although t ...
Select Acetophenones Modulate Flagellar Motility in Chlamydomonas
... (12,13). For example, in a study examining acetophenones for activity against mycobacteria, cytotoxicity was observed against three eukaryotic cell lines (14). The cytotoxicity was not correlated with the antibacterial activity, suggesting different mechanisms. One active compound, 4-nitroacetopheno ...
... (12,13). For example, in a study examining acetophenones for activity against mycobacteria, cytotoxicity was observed against three eukaryotic cell lines (14). The cytotoxicity was not correlated with the antibacterial activity, suggesting different mechanisms. One active compound, 4-nitroacetopheno ...
Asymmetric Cell Divisions: Zygotes of Fucoid Algae as a
... Zygotes of Fucoid Algae as a Model System Zygotes of fucoid algae have, for many years, been a fruitful system in which to study the mechanisms by which cells acquire polarity and regulate asymmetric cell divisions, mainly because they are easy to manipulate and analyze in the laboratory (for recent ...
... Zygotes of Fucoid Algae as a Model System Zygotes of fucoid algae have, for many years, been a fruitful system in which to study the mechanisms by which cells acquire polarity and regulate asymmetric cell divisions, mainly because they are easy to manipulate and analyze in the laboratory (for recent ...
Emerging regulatory mechanisms in ubiquitin
... Although the SCF and APC/C are structurally similar, they differ in complexity. The SCF has only three core subunits (cullin 1, RBX1 and SKP1) but cooperates with multiple different substrate adaptors, the F-box proteins (see figure panel A). The human genome encodes 68 different F-box proteins. By ...
... Although the SCF and APC/C are structurally similar, they differ in complexity. The SCF has only three core subunits (cullin 1, RBX1 and SKP1) but cooperates with multiple different substrate adaptors, the F-box proteins (see figure panel A). The human genome encodes 68 different F-box proteins. By ...
jxb.oxfordjournals.org
... stronger leaf polarity defects; the first two rosette leaves typically appeared lotus like and, in some extreme cases, needle like. In the F3 progeny of three independent homozygous lines, >80% of 35S:miR396a/as2 plants produced lotus-like or needle-like leaves in the first pair of true leaves, whil ...
... stronger leaf polarity defects; the first two rosette leaves typically appeared lotus like and, in some extreme cases, needle like. In the F3 progeny of three independent homozygous lines, >80% of 35S:miR396a/as2 plants produced lotus-like or needle-like leaves in the first pair of true leaves, whil ...
Activation of Heat-Shock Factor by Stretch-Activated
... levels have been suggested as potential mediators for induction of cardiac hypertrophy and IE gene expression.26,27 Since Vandenburgh and Kaufman28 reported that mechanical stretch without confounding factors caused increased protein synthesis in cultured skeletal muscle cells, however, many studies ...
... levels have been suggested as potential mediators for induction of cardiac hypertrophy and IE gene expression.26,27 Since Vandenburgh and Kaufman28 reported that mechanical stretch without confounding factors caused increased protein synthesis in cultured skeletal muscle cells, however, many studies ...
PLoS Pathogens
... JAZ proteins in vitro. Taken together, our results suggest that HopZ1a facilitates bacterial infection by manipulating the JA signaling pathway in Arabidopsis. ...
... JAZ proteins in vitro. Taken together, our results suggest that HopZ1a facilitates bacterial infection by manipulating the JA signaling pathway in Arabidopsis. ...
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP
... heart muscle was severely reduced in LAMP-2-deficient mice (Fig. 3c, d). The contractile developed force at stimulation with 4 Hz was 2.5-fold lower in heart muscle preparations from LAMP-2deficient mice than in those from controls. At a stimulation frequency of 10 Hz the contractile dysfunction was ...
... heart muscle was severely reduced in LAMP-2-deficient mice (Fig. 3c, d). The contractile developed force at stimulation with 4 Hz was 2.5-fold lower in heart muscle preparations from LAMP-2deficient mice than in those from controls. At a stimulation frequency of 10 Hz the contractile dysfunction was ...
IN VITRO BARK EXTRACTS
... new, plant based, risk-free, superior compounds with novel antimicrobial and anticancer activities is the need of the day. The aim of this study was to evaluate the antimicrobial and anticancer effects of bark of Cinnamomum zeylanicum. The antimicrobial activity of extracts of Cinnamomum zeylanicum ...
... new, plant based, risk-free, superior compounds with novel antimicrobial and anticancer activities is the need of the day. The aim of this study was to evaluate the antimicrobial and anticancer effects of bark of Cinnamomum zeylanicum. The antimicrobial activity of extracts of Cinnamomum zeylanicum ...
Whole-cell biocatalysts by design - Microbial Cell Factories
... Although whole-cell biocatalysis is primarily an alternative for in vitro multienzyme cascades, a number of successful and commercially viable whole-cell biocatalysts that use single-step reactions to produce fine chemicals exist [13, 29]. For whole-cell biocatalysis via single-step “pathways”, reco ...
... Although whole-cell biocatalysis is primarily an alternative for in vitro multienzyme cascades, a number of successful and commercially viable whole-cell biocatalysts that use single-step reactions to produce fine chemicals exist [13, 29]. For whole-cell biocatalysis via single-step “pathways”, reco ...
Global microRNA depletion suppresses tumor angiogenesis Please share
... Dicer1 / NSCLC cells showing global differential expression between two genotypes. The X-axis is the log2 fold change of Dicer1 knockout over heterozygotes, and the Y-axis is the statistical significance ( log10 P-value). Genes significantly upregulated are shown as red dots. Genes significantly dow ...
... Dicer1 / NSCLC cells showing global differential expression between two genotypes. The X-axis is the log2 fold change of Dicer1 knockout over heterozygotes, and the Y-axis is the statistical significance ( log10 P-value). Genes significantly upregulated are shown as red dots. Genes significantly dow ...