pdf - John Innes Centre
... legume root surface as a biofilm, which is normally described as a close-knit microbial community that colonizes the surface of a solid substratum. The bacteria within this rhizosphere community interact with each other through a quorum-sensing system based on the exchange of homoserine lactone sign ...
... legume root surface as a biofilm, which is normally described as a close-knit microbial community that colonizes the surface of a solid substratum. The bacteria within this rhizosphere community interact with each other through a quorum-sensing system based on the exchange of homoserine lactone sign ...
Cell cycle–dependent phosphorylation of Sec4p controls membrane
... of the ∼60 human Rabs containing at least one phosphorylated residue (Hornbeck et al., 2015); however, very little is known about the kinases and cellular pathways involved in regulating phosphorylation and how these modifications may affect function. Previous work using Saccharomyces cerevisiae Rab ...
... of the ∼60 human Rabs containing at least one phosphorylated residue (Hornbeck et al., 2015); however, very little is known about the kinases and cellular pathways involved in regulating phosphorylation and how these modifications may affect function. Previous work using Saccharomyces cerevisiae Rab ...
Liver development
... primitive streak give rise to more anterior endoderm (Lawson and Pedersen, 1987). Anterior endoderm fate requires higher levels of nodal signaling than posterior endoderm cells and expresses Foxa2, which is preferentially required to make anterior definitive endoderm (Dufort et al., 1998; Zorn and W ...
... primitive streak give rise to more anterior endoderm (Lawson and Pedersen, 1987). Anterior endoderm fate requires higher levels of nodal signaling than posterior endoderm cells and expresses Foxa2, which is preferentially required to make anterior definitive endoderm (Dufort et al., 1998; Zorn and W ...
Transcription Factor c-Rel B κ Regulation of the IL-21 Gene by the NF-
... and differentiation of the Th cell subsets, Th17 and follicular helper T (TFH) cells. Because of its potent activity in both myeloid and lymphoid cell immune responses, it has been implicated in a number of autoimmune diseases and has also been used as a therapeutic agent in the treatment of some ca ...
... and differentiation of the Th cell subsets, Th17 and follicular helper T (TFH) cells. Because of its potent activity in both myeloid and lymphoid cell immune responses, it has been implicated in a number of autoimmune diseases and has also been used as a therapeutic agent in the treatment of some ca ...
OCTOPUS, a polarly localised membrane
... Arabidopsis genes that share a domain of unknown function (DUF740) (Nagawa et al., 2006) and display no other known protein motifs. The 686 amino acid long OPS protein has a glycine-rich domain at its C terminus, but its structure and glycine content does not classify OPS as a glycine-rich protein ( ...
... Arabidopsis genes that share a domain of unknown function (DUF740) (Nagawa et al., 2006) and display no other known protein motifs. The 686 amino acid long OPS protein has a glycine-rich domain at its C terminus, but its structure and glycine content does not classify OPS as a glycine-rich protein ( ...
Leukaemia Section Anaplastic large cell lymphoma (ALCL) Atlas of Genetics and Cytogenetics
... N-term amino acids from the partner gene fused to the 562 C-term amino acids from ALK (i.e. the entire cytoplasmic portion of ALK with the tyrosine kinase domain); homodimerization of the fusion protein. ...
... N-term amino acids from the partner gene fused to the 562 C-term amino acids from ALK (i.e. the entire cytoplasmic portion of ALK with the tyrosine kinase domain); homodimerization of the fusion protein. ...
Endothelial cell response to different mechanical forces
... stress alters the physiologic properties of the membrane, such as increasing permeability, fluidity, and perturbation, which in turn activates G protein on the cytosolic face of the membrane as early as the first second after applying flow. These accumulating data suggest the possibility that mechan ...
... stress alters the physiologic properties of the membrane, such as increasing permeability, fluidity, and perturbation, which in turn activates G protein on the cytosolic face of the membrane as early as the first second after applying flow. These accumulating data suggest the possibility that mechan ...
Phospholamban Is Present in Endothelial Cells and Modulates
... also measured a significant increase in sensitivity to forskolin in endothelium-intact aortas from WT mice. Importantly, this difference in forskolin-mediated relaxation between endothelium-intact and denuded vessels was blunted in aortas from PLB-KO mice. This suggests that PLB gene ablation result ...
... also measured a significant increase in sensitivity to forskolin in endothelium-intact aortas from WT mice. Importantly, this difference in forskolin-mediated relaxation between endothelium-intact and denuded vessels was blunted in aortas from PLB-KO mice. This suggests that PLB gene ablation result ...
Expression and function of cell adhesion molecules during neural
... Expression and function of cell adhesion molecules during neural crest migration Sonja J. McKeown1, Adam S. Wallace and Richard B. Anderson Department of Anatomy and Neuroscience, University of Melbourne, 3010, VIC, ...
... Expression and function of cell adhesion molecules during neural crest migration Sonja J. McKeown1, Adam S. Wallace and Richard B. Anderson Department of Anatomy and Neuroscience, University of Melbourne, 3010, VIC, ...
The 2015 World Health Organization Classification of Tumors of the
... hematoxylin and eosin (HE)-stained specimens are now considered “obligatory/indispensable,” and others as “optional” according to their importance for diagnosis (Table 2).5 It is hoped that these clarifications will reduce previous ambiguity and may help to overcome the unsatisfactory reproducibilit ...
... hematoxylin and eosin (HE)-stained specimens are now considered “obligatory/indispensable,” and others as “optional” according to their importance for diagnosis (Table 2).5 It is hoped that these clarifications will reduce previous ambiguity and may help to overcome the unsatisfactory reproducibilit ...
lengthened g1 phase indicates differentiation status in
... List of Figures Figure 1: Early human embryonic development includes significant changes in cell cycle features ...................................... 2 Figure 2: Expression profiles of active cell cycle regulators ....................... 5 Figure 3: Image analysis workflow ........................ ...
... List of Figures Figure 1: Early human embryonic development includes significant changes in cell cycle features ...................................... 2 Figure 2: Expression profiles of active cell cycle regulators ....................... 5 Figure 3: Image analysis workflow ........................ ...
NETosis: how vital is it?
... are mutually exclusive. To date, limited evidence exists to support this idea. Alternatively, the possibility exists that neutrophils survive the NETosis process and continue to perform the functions necessary to detect, capture, and contain pathogens. It is worth noting that this mechanism could st ...
... are mutually exclusive. To date, limited evidence exists to support this idea. Alternatively, the possibility exists that neutrophils survive the NETosis process and continue to perform the functions necessary to detect, capture, and contain pathogens. It is worth noting that this mechanism could st ...
Vertebrate somitogenesis: a novel paradigm for animal segmentation?
... third of the PSM (Dubrulle, et al., 2001). The limit between these two domains which marks a critical maturation step in the PSM was termed the determination front (Fig. 4). In chick and fish embryos, the position of the front was shown to be defined by the concentration of the secreted factor FGF8 ...
... third of the PSM (Dubrulle, et al., 2001). The limit between these two domains which marks a critical maturation step in the PSM was termed the determination front (Fig. 4). In chick and fish embryos, the position of the front was shown to be defined by the concentration of the secreted factor FGF8 ...
COUP-TFI and COUP-TFII regulate expression of the NHE through a
... COUP-TFII, is increased for either COUP isoform by the presence of high serum concentrations, and is greatly reduced by mutations preventing COUP binding. In vivo COUP expression in NIH 3T3 cells results in increased synthesis of NHE. Expression of COUP-TFII induced by either retinoic acid or dimeth ...
... COUP-TFII, is increased for either COUP isoform by the presence of high serum concentrations, and is greatly reduced by mutations preventing COUP binding. In vivo COUP expression in NIH 3T3 cells results in increased synthesis of NHE. Expression of COUP-TFII induced by either retinoic acid or dimeth ...
D. Malpighian tubules play similar function as tubular parts of the
... Drosophila brain. Therefore, Mth and Sun delineate a new cross-organ circuitry that modulates physiological insulin level in response to nutrients (Delanoue et al. 2016). F. Renal Cancer Fault in regulation of stem cell behavior results in tissue degeneration, premature aging, and cancer formation. ...
... Drosophila brain. Therefore, Mth and Sun delineate a new cross-organ circuitry that modulates physiological insulin level in response to nutrients (Delanoue et al. 2016). F. Renal Cancer Fault in regulation of stem cell behavior results in tissue degeneration, premature aging, and cancer formation. ...
Emerging Themes of Plant Signal Transduction
... we know that it is a receptor, it does not look like any other receptor so far characterized. Most conspicuously, phytochrome is cytoplasmic, and as yet there is no convincing evidence that it ever uses membranes as a platform to mount its biochemical reactions (Quail, 1991). How the phytochrome mol ...
... we know that it is a receptor, it does not look like any other receptor so far characterized. Most conspicuously, phytochrome is cytoplasmic, and as yet there is no convincing evidence that it ever uses membranes as a platform to mount its biochemical reactions (Quail, 1991). How the phytochrome mol ...
Role of Integration Host Factor in the Transcriptional Activation of
... and examined the effect on flagellar gene expression. The ⌬ihfB strain exhibited a mild defect in cell morphology and impaired motility. Using flagellar promoter reporter fusions, we observed that expression levels of a subset of class III flagellar promoters were decreased by the loss of IHF. Howev ...
... and examined the effect on flagellar gene expression. The ⌬ihfB strain exhibited a mild defect in cell morphology and impaired motility. Using flagellar promoter reporter fusions, we observed that expression levels of a subset of class III flagellar promoters were decreased by the loss of IHF. Howev ...
Manuscrit en préparation (soumission prévue à Int - HAL
... amounts of omega-3 (n-3) fatty acids, display a lower breast cancer risk [1, 2]. This effect seems to be related to specific n-3 polyunsaturated fatty acids and/or to the ratio of n-6 to n-3 fatty acids [3-6]. Long-chain n-3 fatty acids found in fatty cold-water fish, particularly eicosapentaenoic a ...
... amounts of omega-3 (n-3) fatty acids, display a lower breast cancer risk [1, 2]. This effect seems to be related to specific n-3 polyunsaturated fatty acids and/or to the ratio of n-6 to n-3 fatty acids [3-6]. Long-chain n-3 fatty acids found in fatty cold-water fish, particularly eicosapentaenoic a ...
Contributions by members of the TGFbeta superfamily to lens
... β superfamily of growth and differentiation factors, including ABSTRACT Members of the TGFβ β, BMP, activin and nodal families, play important signaling roles throughout developthe TGFβ ment. This paper summarizes some of the functions of these ligands in lens development. Targeted deletion of the g ...
... β superfamily of growth and differentiation factors, including ABSTRACT Members of the TGFβ β, BMP, activin and nodal families, play important signaling roles throughout developthe TGFβ ment. This paper summarizes some of the functions of these ligands in lens development. Targeted deletion of the g ...
Surface CD81 Via Microparticles Release and Intercellular Transfer
... T cells upon activation with anti-CD3 and anti-CD28 mAbs (Fig. 1B, upper panel). A similar reduction was observed on human tonsillar B cells after activation with anti-IgM mAbs and IL-4 (Fig. 1B, lower panel). Flow cytometric analysis with two different antiCD81 mAbs (clones JS81 and 1.3.3.22) yield ...
... T cells upon activation with anti-CD3 and anti-CD28 mAbs (Fig. 1B, upper panel). A similar reduction was observed on human tonsillar B cells after activation with anti-IgM mAbs and IL-4 (Fig. 1B, lower panel). Flow cytometric analysis with two different antiCD81 mAbs (clones JS81 and 1.3.3.22) yield ...
Glucocorticoid Receptor-mediated Suppression of the Interleukin 2
... GR mutant expression vectors on the activity of the cotransfected plL2-CAT. Fig. 1 shows that GR mutants HG8, I204, and to a lesser extent I37, carrying ddetion (HG8) or mutations (I204 and I37) of the NH2-terminal domain, respectively, have decreased Dex-mediated repression of the 11.-2CAT expressi ...
... GR mutant expression vectors on the activity of the cotransfected plL2-CAT. Fig. 1 shows that GR mutants HG8, I204, and to a lesser extent I37, carrying ddetion (HG8) or mutations (I204 and I37) of the NH2-terminal domain, respectively, have decreased Dex-mediated repression of the 11.-2CAT expressi ...
full text pdf
... perturbation of the photosynthetic electron transfer produces three types of redox signals [34]. Class 1 signaling originates from specific redox pairs in the photosynthetic electron transport chain, e.g. the reduced and oxidized plastoquinone (PQ), class 2 signaling depends on the redox state of st ...
... perturbation of the photosynthetic electron transfer produces three types of redox signals [34]. Class 1 signaling originates from specific redox pairs in the photosynthetic electron transport chain, e.g. the reduced and oxidized plastoquinone (PQ), class 2 signaling depends on the redox state of st ...
Redox signals as a language of interorganellar
... perturbation of the photosynthetic electron transfer produces three types of redox signals [34]. Class 1 signaling originates from specific redox pairs in the photosynthetic electron transport chain, e.g. the reduced and oxidized plastoquinone (PQ), class 2 signaling depends on the redox state of st ...
... perturbation of the photosynthetic electron transfer produces three types of redox signals [34]. Class 1 signaling originates from specific redox pairs in the photosynthetic electron transport chain, e.g. the reduced and oxidized plastoquinone (PQ), class 2 signaling depends on the redox state of st ...
