ppt - IISER Pune
... Dan H Sanes, Thomas A Reh, William A Harris. Development of the Nervous System 2005 – Chapter 8 5th September 2013 ...
... Dan H Sanes, Thomas A Reh, William A Harris. Development of the Nervous System 2005 – Chapter 8 5th September 2013 ...
Nociceptors: the sensors of the pain pathway
... glutamate as their primary neurotransmitter as well as other components including peptides (e.g., substance P, calcitonin generelated peptide [CGRP], somatostatin) important in both central synaptic signaling and efferent signaling in the skin (13). Invasion of action potentials into the nociceptor ...
... glutamate as their primary neurotransmitter as well as other components including peptides (e.g., substance P, calcitonin generelated peptide [CGRP], somatostatin) important in both central synaptic signaling and efferent signaling in the skin (13). Invasion of action potentials into the nociceptor ...
Jasmonate Biosynthesis, Perception and Function in Plant
... compounds represent a highly diverse group of substances that are involved in a number of developmental processes and various stress responses in plants (Andersson et al., 2006). Plant oxylipins can be formed enzymatically, by initial oxidation by lipoxygenases (LOXs) or α-dioxygenases (α-DOXs); how ...
... compounds represent a highly diverse group of substances that are involved in a number of developmental processes and various stress responses in plants (Andersson et al., 2006). Plant oxylipins can be formed enzymatically, by initial oxidation by lipoxygenases (LOXs) or α-dioxygenases (α-DOXs); how ...
Capacitation-associated Changes in Protein
... ABSTRACT : The aim of this study was to evaluate the effects of Ca2+, HCO3- and BSA on the in vitro capacitation-associated protein tyrosine phosphorylation, hyperactivation and acrosome reaction in guinea pig sperm. Caudal epididymal sperm were incubated in four different groups: modified TALP (Tyr ...
... ABSTRACT : The aim of this study was to evaluate the effects of Ca2+, HCO3- and BSA on the in vitro capacitation-associated protein tyrosine phosphorylation, hyperactivation and acrosome reaction in guinea pig sperm. Caudal epididymal sperm were incubated in four different groups: modified TALP (Tyr ...
MAPK-mediated Phosphorylation of GATA-1 Promotes Expression and Cell Survival* Bcl-X □
... Ba/F3, inhibition of mitogen-activated protein kinase, a member of the MAPK/c-Jun N-terminal kinase/stressactivated protein kinase kinase family that plays an important role in cell growth and death control, rapidly leads to severe apoptosis. However, most of the antiapoptotic substrates of MAPK rem ...
... Ba/F3, inhibition of mitogen-activated protein kinase, a member of the MAPK/c-Jun N-terminal kinase/stressactivated protein kinase kinase family that plays an important role in cell growth and death control, rapidly leads to severe apoptosis. However, most of the antiapoptotic substrates of MAPK rem ...
the diversity of plastid - University of Wisconsin Oshkosh
... with its higher level of tissue complexity, that has fully availed itself of the diversity available in plastid evolution. Seeds, meristematic tissues, and several other tissues contain proplastids, the smallest and least complicated member of the plastid family, and the ontological precursor to all ...
... with its higher level of tissue complexity, that has fully availed itself of the diversity available in plastid evolution. Seeds, meristematic tissues, and several other tissues contain proplastids, the smallest and least complicated member of the plastid family, and the ontological precursor to all ...
Co-Expression of Arabidopsis thaliana Phytochelatin Synthase and Treponema denticola
... for applications under aerobic conditions. Wang et al. (2001) functionally expressed a cysteine desulfhydrase (CysDes) from Treponema denticola in E. coli for the aerobic sulfide production and heavy metal precipitation using cysteine as the substrate. Apart from the formation of insoluble arsenic tr ...
... for applications under aerobic conditions. Wang et al. (2001) functionally expressed a cysteine desulfhydrase (CysDes) from Treponema denticola in E. coli for the aerobic sulfide production and heavy metal precipitation using cysteine as the substrate. Apart from the formation of insoluble arsenic tr ...
12 October 2000
... it cannot explain how the first, most upstream caspase gets activated. At least two other approaches are used to get the ball rolling. Induced proximity Caspase-8 is the key initiator caspase in the death-receptor pathway (see review in this issue by Krammer, pages 789–795). Upon ligand binding, dea ...
... it cannot explain how the first, most upstream caspase gets activated. At least two other approaches are used to get the ball rolling. Induced proximity Caspase-8 is the key initiator caspase in the death-receptor pathway (see review in this issue by Krammer, pages 789–795). Upon ligand binding, dea ...
Document
... Krebs Cycle per each PYR per 2 cycles @ Fatty-AcoA-DH + 2 NADH + 3 AcoA PDH - 2CO2 per each AcoA + 2 FADH2 = 4 ATP + 2 NADH + 2 NADH = 6 ATP ISDH -2CO2 + 2 NADH ---------KGDH -2CO2 thiokinase + 2 GTP + 10 ATP SDH + 2 FADH2 MDH + 2 NADH Totals 6C FFA 1 glucose = 2 PYR = 2 AcoA ---------> B-OX = 10 AT ...
... Krebs Cycle per each PYR per 2 cycles @ Fatty-AcoA-DH + 2 NADH + 3 AcoA PDH - 2CO2 per each AcoA + 2 FADH2 = 4 ATP + 2 NADH + 2 NADH = 6 ATP ISDH -2CO2 + 2 NADH ---------KGDH -2CO2 thiokinase + 2 GTP + 10 ATP SDH + 2 FADH2 MDH + 2 NADH Totals 6C FFA 1 glucose = 2 PYR = 2 AcoA ---------> B-OX = 10 AT ...
here - Newtricious
... Research on model systems demonstrates that o-3 LCPUFAs also have the capacity to affect production and activation of angiogenic growth factors, arachidonic acid (AA)-based vasoregulatory eicosanoids, and MMPs. Eicosapentaenoic acid (EPA), a substrate for DHA, is the parent fatty acid for a family o ...
... Research on model systems demonstrates that o-3 LCPUFAs also have the capacity to affect production and activation of angiogenic growth factors, arachidonic acid (AA)-based vasoregulatory eicosanoids, and MMPs. Eicosapentaenoic acid (EPA), a substrate for DHA, is the parent fatty acid for a family o ...
Enzymes of the mevalonate pathway of isoprenoid
... These enzymes had been isolated and classical enzymological and biochemical characterization had been performed prior to the evolution of experimental tools that have expedited the understanding the molecular basis of enzyme function. These enzymes are significant in animals since several have been ...
... These enzymes had been isolated and classical enzymological and biochemical characterization had been performed prior to the evolution of experimental tools that have expedited the understanding the molecular basis of enzyme function. These enzymes are significant in animals since several have been ...
Nonsense-mediated mRNA decay - Case Western Reserve University
... Upf3 is required to trigger mRNA decay, thus providing a physical and functional link between the EJC and NMD [41!!]. An mRNA can also be recognized as aberrant through mRNP features independent of an EJC, as is the case for several mammalian genes [42]. Moreover, in yeast and Drosophila, for exampl ...
... Upf3 is required to trigger mRNA decay, thus providing a physical and functional link between the EJC and NMD [41!!]. An mRNA can also be recognized as aberrant through mRNP features independent of an EJC, as is the case for several mammalian genes [42]. Moreover, in yeast and Drosophila, for exampl ...
Defining a Centromere-like Element in Bacillus
... progeny. During sporulation, however, the bacterium divides asymmetrically, forming a septum near a pole of the developing cell (sporangium). Formation of this polar septum divides the sporangium into two compartments called the forespore and the approximately eight-times larger mother cell (Stragie ...
... progeny. During sporulation, however, the bacterium divides asymmetrically, forming a septum near a pole of the developing cell (sporangium). Formation of this polar septum divides the sporangium into two compartments called the forespore and the approximately eight-times larger mother cell (Stragie ...
Liposome
... The lipid film obtained was dispersed in PBS containing hLf and incubated for 5 hours at room temperature to facilitate the annealing process. Five freeze - thaw cycles were performed to obtain a suitable size (about 200 nm) and a high efficiency of hLf incorporation in multivesicular liposomes (mul ...
... The lipid film obtained was dispersed in PBS containing hLf and incubated for 5 hours at room temperature to facilitate the annealing process. Five freeze - thaw cycles were performed to obtain a suitable size (about 200 nm) and a high efficiency of hLf incorporation in multivesicular liposomes (mul ...
RNA aptamers as genetic control devices: The potential of
... genomes of both pro- and eukaryotes [9, 10]. Sophisticated molecular systems that sense external stimuli and respond to these by modulating the output of a cellular process are another important application in biotechnology. Genetically, this problem can be tackled by several different approaches of ...
... genomes of both pro- and eukaryotes [9, 10]. Sophisticated molecular systems that sense external stimuli and respond to these by modulating the output of a cellular process are another important application in biotechnology. Genetically, this problem can be tackled by several different approaches of ...
Flavors of Protein Disorder
... ago7, and that some proteins don’t fold due to an atypical amino acid composition was suggested more than 20 years ago8, 9. More recently, such proteins have been called "natively unfolded"10, "intrinsically unstructured"1, and “intrinsically disordered”2. The failure to self-fold into specific 3-D ...
... ago7, and that some proteins don’t fold due to an atypical amino acid composition was suggested more than 20 years ago8, 9. More recently, such proteins have been called "natively unfolded"10, "intrinsically unstructured"1, and “intrinsically disordered”2. The failure to self-fold into specific 3-D ...
RNA Processing Bodies, Peroxisomes, Golgi Bodies, Mitochondria
... et al. 2010). Interestingly, although actin filaments sustain long-distance transport of plant organelles, it has recently been observed that microtubules influence short-distance behavior, causing pauses for both peroxisomes (Chuong et al. 2005) and the Golgi (Crowell et al. 2009, Gutierrez et al. ...
... et al. 2010). Interestingly, although actin filaments sustain long-distance transport of plant organelles, it has recently been observed that microtubules influence short-distance behavior, causing pauses for both peroxisomes (Chuong et al. 2005) and the Golgi (Crowell et al. 2009, Gutierrez et al. ...
the physiology of mechanoelectrical transduction channels in hearing
... the hallmark of neural activity in animals. Common examples include the voltage-gated Na⫹ and K⫹ channels, underlying the nerve action potential, and ligand-gated channels, such as the glutamate and GABA receptors, which mediate excitatory and inhibitory synaptic transmission. Both types of ion chan ...
... the hallmark of neural activity in animals. Common examples include the voltage-gated Na⫹ and K⫹ channels, underlying the nerve action potential, and ligand-gated channels, such as the glutamate and GABA receptors, which mediate excitatory and inhibitory synaptic transmission. Both types of ion chan ...
Relationship Between the Occurrence of Cysteine in Proteins and
... expansion of the genetic code is primarily based on the anomalous codon allocations of various species (Osawa et al. 1992; Bauman and Oro 1993). In addition, Doring and Marliere (1998) showed that mutant tRNAs that incorporate cysteine at positions corresponding to the isoleucine or methionine codon ...
... expansion of the genetic code is primarily based on the anomalous codon allocations of various species (Osawa et al. 1992; Bauman and Oro 1993). In addition, Doring and Marliere (1998) showed that mutant tRNAs that incorporate cysteine at positions corresponding to the isoleucine or methionine codon ...
Protected Cell Companies Act 1999
... cell company which is registered by way of continuation of a foreign company, means the Articles of Association as registered with the Registrar by way of continuation; “Authority” means the Mauritius Offshore Business Activities Authority established under the Mauritius Offshore Business Activities ...
... cell company which is registered by way of continuation of a foreign company, means the Articles of Association as registered with the Registrar by way of continuation; “Authority” means the Mauritius Offshore Business Activities Authority established under the Mauritius Offshore Business Activities ...
Bursting thalamic responses in awake monkey contribute to visual
... off, for which they were rewarded with water or juice. Figure 1B left shows the averaged responses for the 42 cells recorded during this task, separated into trials in which on the RF was the target (n = 993) or a distractor (n = 2618). It is already clear from this figure that the initial part of t ...
... off, for which they were rewarded with water or juice. Figure 1B left shows the averaged responses for the 42 cells recorded during this task, separated into trials in which on the RF was the target (n = 993) or a distractor (n = 2618). It is already clear from this figure that the initial part of t ...
Comparing The Effects of Small Molecules BIX
... 50-fold for three-factor (Oct4, Sox2 and Klf4) and four-factor (Oct4, Sox2, Klf4 and c-Myc) reprogramming respectively. VPA enhances reprogramming efficiency and consequently provides a chance for reducing the number of required reprogramming factors. In the presence of VPA, the three-factor-infecte ...
... 50-fold for three-factor (Oct4, Sox2 and Klf4) and four-factor (Oct4, Sox2, Klf4 and c-Myc) reprogramming respectively. VPA enhances reprogramming efficiency and consequently provides a chance for reducing the number of required reprogramming factors. In the presence of VPA, the three-factor-infecte ...
Fanconi anemia protein FANCD2 inhibits TRF1
... Fanconi anemia (FA) is a rare recessive disorder associated with chromosomal fragility, aplastic anemia, congenital abnormalities and a predisposition to cancer [1,2]. Cells from FA patients exhibit hypersensitivity to DNA cross-linking agents suggesting the role of FA proteins in the repair of dama ...
... Fanconi anemia (FA) is a rare recessive disorder associated with chromosomal fragility, aplastic anemia, congenital abnormalities and a predisposition to cancer [1,2]. Cells from FA patients exhibit hypersensitivity to DNA cross-linking agents suggesting the role of FA proteins in the repair of dama ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.