Histamine and Histamine Intolerance
... • VERY HIGH DENSITY IN BRAIN REGIONS CONCERNED WITH NEUROENDOCRINE, BEHAVIORAL, AND NUTRITIONAL STATE CONTROL, LIKE THE HYPOTHALAMUS, AMINERGIC AND CHOLINERGIC BRAINSTEM NUCLEI, THALAMUS, AND CORTEX • HISTAMINE VIA H1R EXCITES NEURONS IN MOST BRAIN REGIONS, INCLUDING BRAIN STEM, ...
... • VERY HIGH DENSITY IN BRAIN REGIONS CONCERNED WITH NEUROENDOCRINE, BEHAVIORAL, AND NUTRITIONAL STATE CONTROL, LIKE THE HYPOTHALAMUS, AMINERGIC AND CHOLINERGIC BRAINSTEM NUCLEI, THALAMUS, AND CORTEX • HISTAMINE VIA H1R EXCITES NEURONS IN MOST BRAIN REGIONS, INCLUDING BRAIN STEM, ...
ภาพนิ่ง 1
... ABA seems to be able to act via one or more calcium-independent pathways. A raise in cytosolic pH can lead to the activation of outward K+ channels, and one effectof the abi1 mutation is to render these K+ channels insensitive to pH. ...
... ABA seems to be able to act via one or more calcium-independent pathways. A raise in cytosolic pH can lead to the activation of outward K+ channels, and one effectof the abi1 mutation is to render these K+ channels insensitive to pH. ...
Occlusive thrombi arise in mammals but not birds in
... Thrombocytes and lymphocytes express roughly equal amounts of p2ry12 and high cycle thresholds (30.3 and 28.0 for thrombocytes and lymphocytes, respectively) suggests a low-level of expression in both cell types. This result is consistent with previous studies indicating that avian thrombocytes neit ...
... Thrombocytes and lymphocytes express roughly equal amounts of p2ry12 and high cycle thresholds (30.3 and 28.0 for thrombocytes and lymphocytes, respectively) suggests a low-level of expression in both cell types. This result is consistent with previous studies indicating that avian thrombocytes neit ...
The amoebae plate test implicates a paralogue of lpxB in the
... domain, and thus this membrane protein might play a direct role in altering host cell vesicle trafficking (Morozova et al., 2004). Biochemical analysis of the soluble Icm proteins revealed that IcmS/IcmW and IcmR/IcmQ directly bind to each other (Coers et al., 2000). IcmR functions as a chaperone of ...
... domain, and thus this membrane protein might play a direct role in altering host cell vesicle trafficking (Morozova et al., 2004). Biochemical analysis of the soluble Icm proteins revealed that IcmS/IcmW and IcmR/IcmQ directly bind to each other (Coers et al., 2000). IcmR functions as a chaperone of ...
Local chromosome context is a major determinant of crossover
... Meiotic recombination pathways diverge after DSB formation and homolog-directed strand invasion. In budding yeast, about half of meiotic events form NCOs via synthesis-dependent strand annealing, a mechanism that does not involve stable recombination intermediates (Allers and Lichten, 2001a; McMahil ...
... Meiotic recombination pathways diverge after DSB formation and homolog-directed strand invasion. In budding yeast, about half of meiotic events form NCOs via synthesis-dependent strand annealing, a mechanism that does not involve stable recombination intermediates (Allers and Lichten, 2001a; McMahil ...
Activation of DREAM (Downstream Regulatory
... ABSTRACT BACKGROUND: Previous studies have implicated the cyclic adenosine monophosphate/protein kinase A pathway as well as FosB and dynorphin-B expression mediated by dopamine D1 receptor stimulation in the development of 3,4-dihydroxyphenyl-L-alanine (L-DOPA)–induced dyskinesia. The magnitude of ...
... ABSTRACT BACKGROUND: Previous studies have implicated the cyclic adenosine monophosphate/protein kinase A pathway as well as FosB and dynorphin-B expression mediated by dopamine D1 receptor stimulation in the development of 3,4-dihydroxyphenyl-L-alanine (L-DOPA)–induced dyskinesia. The magnitude of ...
Enzymes:The Catalysts of Life I
... Figure 6-2a. Substrate binding depends on amino acid residues from various positions along the polypeptide, including residues from positions 33–36, 46, 60–64, and 102–110. Catalysis involves two specific residues: a glutamate at position 35 (Glu-35) and an aspartic acid at position 52 (Asp-52). The ...
... Figure 6-2a. Substrate binding depends on amino acid residues from various positions along the polypeptide, including residues from positions 33–36, 46, 60–64, and 102–110. Catalysis involves two specific residues: a glutamate at position 35 (Glu-35) and an aspartic acid at position 52 (Asp-52). The ...
... groups, such as Gal/GalNAc-specific, glucose/mannose-specific, fucose specific, GlcNAc specific, and sialic acid specific lectins (Goldstein & Poretz, 1986). Since mannose is widespread in animals, insects and microorganisms, mannose-binding lectins are considered biologically important proteins (Wo ...
Divalent Cation-Dependent Formation of
... yet it plays an outsized role in many critical processes, including cell division (1), endocytosis and exocytosis (2), and cell motility (3). Evidence exists that PIP2 forms clusters (4) at the submicron scale in vitro, and it has been speculated that similar domains might form under roughly physiol ...
... yet it plays an outsized role in many critical processes, including cell division (1), endocytosis and exocytosis (2), and cell motility (3). Evidence exists that PIP2 forms clusters (4) at the submicron scale in vitro, and it has been speculated that similar domains might form under roughly physiol ...
Role of Template Activating Factor-I as a
... separated by 10% SDS-PAGE and visualized with Coomassie Brilliant Blue staining. Lane M contains molecular size markers. (B) Formation of histone H1.1NCPs complexes was examined by nucleoprotein gel analyses. The 196 bp 5S rRNA gene fragments or NCPs (0.4 pmol of DNA) assembled on the same DNA with ...
... separated by 10% SDS-PAGE and visualized with Coomassie Brilliant Blue staining. Lane M contains molecular size markers. (B) Formation of histone H1.1NCPs complexes was examined by nucleoprotein gel analyses. The 196 bp 5S rRNA gene fragments or NCPs (0.4 pmol of DNA) assembled on the same DNA with ...
Receptor Regulation of the Volume-Sensitive Efflux of Taurine and
... neural preparations can be enhanced after activation of cellsurface receptors. The latter include P2Y purinergic receptors in rat astrocytes (Mongin and Kimelberg, 2002, 2005), M3 muscarinic cholinergic receptors (mAChRs), lysophosphatidic and sphingosine 1-phosphate receptors in human SHSY5Y neurob ...
... neural preparations can be enhanced after activation of cellsurface receptors. The latter include P2Y purinergic receptors in rat astrocytes (Mongin and Kimelberg, 2002, 2005), M3 muscarinic cholinergic receptors (mAChRs), lysophosphatidic and sphingosine 1-phosphate receptors in human SHSY5Y neurob ...
Functional characterization of the Mycobacterium
... Eukaryotic-like Ser/Thr protein kinases (STPKs) are present in many bacterial species, where they control various physiological and virulence processes by enabling microbial adaptation to specific environmental signals. PknJ is the only member of the 11 STPKs identified in Mycobacterium tuberculosis ...
... Eukaryotic-like Ser/Thr protein kinases (STPKs) are present in many bacterial species, where they control various physiological and virulence processes by enabling microbial adaptation to specific environmental signals. PknJ is the only member of the 11 STPKs identified in Mycobacterium tuberculosis ...
Fear conditioning, synaptic plasticity and the amygdala
... over-generalization of fear associations and failure to extinguish learned fear (Figure 2) [22–31]. Animal models that mimic these behavioral abnormalities, such as animals trained in the fear conditioning or extinction learning paradigms, require synaptic plasticity [35–44]. Therefore, impairment o ...
... over-generalization of fear associations and failure to extinguish learned fear (Figure 2) [22–31]. Animal models that mimic these behavioral abnormalities, such as animals trained in the fear conditioning or extinction learning paradigms, require synaptic plasticity [35–44]. Therefore, impairment o ...
Induction of Apoptosis through B-cell Receptor Cross-linking
... morphological evidence of mitochondrial damage, suggesting the involvement of mitochondria in BcR-triggered apoptosis, and this was inhibited by FB1. Moreover, a loss of mitochondrial membrane potential was observed in Ramos cells after BcR cross-linking, which was inhibited by the addition of FB1. ...
... morphological evidence of mitochondrial damage, suggesting the involvement of mitochondria in BcR-triggered apoptosis, and this was inhibited by FB1. Moreover, a loss of mitochondrial membrane potential was observed in Ramos cells after BcR cross-linking, which was inhibited by the addition of FB1. ...
Retinal Ganglion Cell Axon Guidance in the Mouse Optic Chiasm
... cross the ventral midline of the diencephalon (developing hypothalamus) or turn away from it, forming an x-shaped fiber pathway, the optic chiasm. Contralaterally projecting RGCs are distributed throughout the retina, whereas ipsilaterally projecting cells are found exclusively in the ventrotemporal ...
... cross the ventral midline of the diencephalon (developing hypothalamus) or turn away from it, forming an x-shaped fiber pathway, the optic chiasm. Contralaterally projecting RGCs are distributed throughout the retina, whereas ipsilaterally projecting cells are found exclusively in the ventrotemporal ...
VAAM-Jahrestagung 2016 13.–16. März in Jena
... Product Research and Infection Biology – Hans Knöll Institute – (HKI). The team of Axel Brakhage (Director HKI, Head of the Department Molecular and Applied Microbiology, and Chair of Microbiology and Molecular Biology at FSU Jena) is investigating the infection biology of the human pathogenic fungu ...
... Product Research and Infection Biology – Hans Knöll Institute – (HKI). The team of Axel Brakhage (Director HKI, Head of the Department Molecular and Applied Microbiology, and Chair of Microbiology and Molecular Biology at FSU Jena) is investigating the infection biology of the human pathogenic fungu ...
review neurochemical markers of alcoholism vulnerability in humans
... alcoholism has attempted to shed light on this basic issue. This research has focused on various behavioural, electrophysiological, and neurochemical characteristics that may be related to alcoholism vulnerability (Begleiter and Porjesz, 1988; Farren and Tipton, 1999; Schuckit, 1999; Van der Stelt, ...
... alcoholism has attempted to shed light on this basic issue. This research has focused on various behavioural, electrophysiological, and neurochemical characteristics that may be related to alcoholism vulnerability (Begleiter and Porjesz, 1988; Farren and Tipton, 1999; Schuckit, 1999; Van der Stelt, ...
Force generation by kinesin and myosin cytoskeletal motor proteins
... conserved motor domain, as well as the N-terminus of the first bstrand of the motor domain. In kinesin family members with an N-terminal motor domain, helix a6 is followed by the neck linker (Kozielski et al., 1997) (Box 1), which has been shown to be crucial for movement (Clancy et al., 2011), wher ...
... conserved motor domain, as well as the N-terminus of the first bstrand of the motor domain. In kinesin family members with an N-terminal motor domain, helix a6 is followed by the neck linker (Kozielski et al., 1997) (Box 1), which has been shown to be crucial for movement (Clancy et al., 2011), wher ...
PDF hosted at the Radboud Repository of the Radboud University
... itochondria are motile organelles that not only produce energy in the form of ATP, but also participate in a number of intracellular processes such as the generation, modulation, and propagation of cytosolic Ca2þ signals and the control of life and death through apoptosis. In addition, they are a co ...
... itochondria are motile organelles that not only produce energy in the form of ATP, but also participate in a number of intracellular processes such as the generation, modulation, and propagation of cytosolic Ca2þ signals and the control of life and death through apoptosis. In addition, they are a co ...
Multiple Functions of the New Cytokine
... The TSLP forms can be produced by a number of cell types, including epithelial and dendritic cells (DCs). lfTSLP can activate mast cells, DCs, and T cells through binding to the lfTSLP receptor (TSLPR) and has a pro-inflammatory function. In contrast, sfTSLP inhibits cytokine secretion of DCs, but t ...
... The TSLP forms can be produced by a number of cell types, including epithelial and dendritic cells (DCs). lfTSLP can activate mast cells, DCs, and T cells through binding to the lfTSLP receptor (TSLPR) and has a pro-inflammatory function. In contrast, sfTSLP inhibits cytokine secretion of DCs, but t ...
IDENTIFICATION AND CHARACTERIZATION OF SYNAPTONEMAL
... Ad (3). The order of events during meiotic prophase at the DNA-level and at the level of chromatin organization was studied by Padmore et al. (1991) in synchronized cultures of yeast. From this study it appears that the tripartite structure has no function in the initial event at the DNA-level prece ...
... Ad (3). The order of events during meiotic prophase at the DNA-level and at the level of chromatin organization was studied by Padmore et al. (1991) in synchronized cultures of yeast. From this study it appears that the tripartite structure has no function in the initial event at the DNA-level prece ...
Imaging Auditory Representations of Song and Syllables in
... relating a neuron’s activity to the functional organization of surrounding neurons. Moreover, HVC contains at least three cell types, including one PN (HVCRA) that innervates the song motor nucleus RA, another PN (HVCX) that innervates a striatopallidal region (Area X), and interneurons (HVCI) (see ...
... relating a neuron’s activity to the functional organization of surrounding neurons. Moreover, HVC contains at least three cell types, including one PN (HVCRA) that innervates the song motor nucleus RA, another PN (HVCX) that innervates a striatopallidal region (Area X), and interneurons (HVCI) (see ...
Reduced initiation frequency from oriC restores viability of a
... E. coli cells with reduced DnaA protein activity, due either to certain mutations in domain III or IV of the protein, or to the introduction of additional datA sites, initiate replication at an increased cell mass per origin. Initiations are often asynchronous, indicating that not all origins are in ...
... E. coli cells with reduced DnaA protein activity, due either to certain mutations in domain III or IV of the protein, or to the introduction of additional datA sites, initiate replication at an increased cell mass per origin. Initiations are often asynchronous, indicating that not all origins are in ...
A Receptor-Like Kinase Mediates Ammonium
... tip growth by ROP GTPase and by the nitrogen source modulated pH fluctuations (Bloch et al., 2011). A range of transporters in root hairs transport nitrogen, calcium (Ca), potassium (K), and sulfate (Libault et al., 2010). Nitrogen is an essential macronutrient for plant growth and development, and n ...
... tip growth by ROP GTPase and by the nitrogen source modulated pH fluctuations (Bloch et al., 2011). A range of transporters in root hairs transport nitrogen, calcium (Ca), potassium (K), and sulfate (Libault et al., 2010). Nitrogen is an essential macronutrient for plant growth and development, and n ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.