
Stem cell factor induces outgrowth of c-kit-positive
... c-kit receptors without tyrosine kinase activity. rmSCF also had a trophic effect on c-kit-positive neurons in the culture of dissociated DRG cells. Most c-kit-positive neurons appeared to respond to NGF as well, and the SCF-responsive subpopulation represented about 10% of NGF-responsive neurons. r ...
... c-kit receptors without tyrosine kinase activity. rmSCF also had a trophic effect on c-kit-positive neurons in the culture of dissociated DRG cells. Most c-kit-positive neurons appeared to respond to NGF as well, and the SCF-responsive subpopulation represented about 10% of NGF-responsive neurons. r ...
Gene Section SPP1 (secreted phosphoprotein 1) Atlas of Genetics and Cytogenetics
... - Exon 3 and 5, the two characteristic Ser-Ser-Glu-Glu phosphorylation sequences. - Exon 4, the two transglutaminase-reactive glutamine residues. - Exon 6, the aspartic-rich sequence. - Exon 7 is the largest exon encoding approzimately half of the proteins including the RGD motif and the central thr ...
... - Exon 3 and 5, the two characteristic Ser-Ser-Glu-Glu phosphorylation sequences. - Exon 4, the two transglutaminase-reactive glutamine residues. - Exon 6, the aspartic-rich sequence. - Exon 7 is the largest exon encoding approzimately half of the proteins including the RGD motif and the central thr ...
PDF data (121 pages / 16.7MB)
... (Consultation for grants & patents, Fusion research program, etc.) ...
... (Consultation for grants & patents, Fusion research program, etc.) ...
Physiological Aspects Of Neuromuscular Transmission
... It employs the neurotransmitter nor epinephrine, other mono amines & neuropeptides. They act through second messenger system such as cyclic AMP. The receptor is not an ion gate but an integral protein associated with a Gprotein. ...
... It employs the neurotransmitter nor epinephrine, other mono amines & neuropeptides. They act through second messenger system such as cyclic AMP. The receptor is not an ion gate but an integral protein associated with a Gprotein. ...
Lesson (1) Cell theory
... cells and gives them definite shapes. Cell membrane: A thin membrane which surrounds all cells, it consists of phospholipid bi-layer and allows the passage of substances to and from the cell. Nucleus: The largest and most obvious organelle in eukaryotic cells which carries chromosomes which are resp ...
... cells and gives them definite shapes. Cell membrane: A thin membrane which surrounds all cells, it consists of phospholipid bi-layer and allows the passage of substances to and from the cell. Nucleus: The largest and most obvious organelle in eukaryotic cells which carries chromosomes which are resp ...
Newcastle disease virus may enter cells by caveolae
... virus (Empig & Goldsmith, 2002) and BK polyomavirus (Eash et al., 2004) have also been reported to enter via caveolae. It has been proposed that murine polyomavirus enters cells through non-clathrin-, non-caveolae-dependent pathways (Gilbert & Benjamin, 2000). Additionally, the human enterovirus EV- ...
... virus (Empig & Goldsmith, 2002) and BK polyomavirus (Eash et al., 2004) have also been reported to enter via caveolae. It has been proposed that murine polyomavirus enters cells through non-clathrin-, non-caveolae-dependent pathways (Gilbert & Benjamin, 2000). Additionally, the human enterovirus EV- ...
PDF - SAGE Journals
... Methanococcus jannaschii is an autotrophic archaeon originally isolated from an oceanic thermal vent. The primary metabolic pathway for energy production in this hyperthermophilic microbe is methanogenesis from H2 and CO2. As an autotroph, M. jannaschii requires only CO2 as a carbon source for synth ...
... Methanococcus jannaschii is an autotrophic archaeon originally isolated from an oceanic thermal vent. The primary metabolic pathway for energy production in this hyperthermophilic microbe is methanogenesis from H2 and CO2. As an autotroph, M. jannaschii requires only CO2 as a carbon source for synth ...
Signals and Structural Features Involved in Integral Membrane
... are located at the junctures between the three nuclear envelope membrane domains, they may play an important role in establishing and maintaining the nonrandom segregation of integral proteins between these membranes. Several integral membrane proteins that are nonrandomly localized in the membrane ...
... are located at the junctures between the three nuclear envelope membrane domains, they may play an important role in establishing and maintaining the nonrandom segregation of integral proteins between these membranes. Several integral membrane proteins that are nonrandomly localized in the membrane ...
Dynamics of the trp Operon
... The five genes are transcribed as a single mRNA molecule, allowing their expression to be controlled coordinately. There is one promoter. Within the promoter is an operator. Tryptophan repressor can bind to operator and deny access to RNA polymerase. ...
... The five genes are transcribed as a single mRNA molecule, allowing their expression to be controlled coordinately. There is one promoter. Within the promoter is an operator. Tryptophan repressor can bind to operator and deny access to RNA polymerase. ...
TARGET: a new method for predicting protein subcellular
... Advance Access publication September 6, 2005 ...
... Advance Access publication September 6, 2005 ...
Protein Arginine Methylation in Candida albicans: Role
... eukaryotes, including protein transport, transcriptional activation, pre-mRNA splicing, and signaling pathways (5, 6). Effects of arginine methylation on intracellular transport can vary among eukaryotes: methylation facilitates nuclear export of several RNA-binding proteins in Saccharomyces cerevis ...
... eukaryotes, including protein transport, transcriptional activation, pre-mRNA splicing, and signaling pathways (5, 6). Effects of arginine methylation on intracellular transport can vary among eukaryotes: methylation facilitates nuclear export of several RNA-binding proteins in Saccharomyces cerevis ...
Bio 226: Cell and Molecular Biology
... Nutrient assimilation Assimilating N and S is very expensive! • Reducing NO3- to NH4+ costs 8 e- (1 NADPH + 6 Fd) • Assimilating NH4+ into amino acids also costs ATP + e• Nitrogen fixation costs 16 ATP + 8 e• SO42- reduction to S2- costs 8 e- + 2ATP • S2- assimilation into Cysteine costs 2 more e• ...
... Nutrient assimilation Assimilating N and S is very expensive! • Reducing NO3- to NH4+ costs 8 e- (1 NADPH + 6 Fd) • Assimilating NH4+ into amino acids also costs ATP + e• Nitrogen fixation costs 16 ATP + 8 e• SO42- reduction to S2- costs 8 e- + 2ATP • S2- assimilation into Cysteine costs 2 more e• ...
Structural basis of ubiquitylation Andrew P VanDemark and
... Doc domain adopts a ‘jelly roll’ fold, which has been seen in many other protein structures and typically functions to bind a ligand, such as a sugar, nucleotide, phospholipid, nucleic acid or protein. Interestingly, the conserved APC10 residues cluster at the putative ligand-binding cleft and a tem ...
... Doc domain adopts a ‘jelly roll’ fold, which has been seen in many other protein structures and typically functions to bind a ligand, such as a sugar, nucleotide, phospholipid, nucleic acid or protein. Interestingly, the conserved APC10 residues cluster at the putative ligand-binding cleft and a tem ...
Plant and Soil
... Plasma membrane H+ -ATPases: an overview Plasma membrane H+ -ATPases of plants and fungi are composed of a single catalytic polypeptide with an approximate molecular weight of 100 kDa that is phosphorylated and dephosphorylated during its catalytic cycle (Briskin and Hanson, 1992; Serrano, 1989). Th ...
... Plasma membrane H+ -ATPases: an overview Plasma membrane H+ -ATPases of plants and fungi are composed of a single catalytic polypeptide with an approximate molecular weight of 100 kDa that is phosphorylated and dephosphorylated during its catalytic cycle (Briskin and Hanson, 1992; Serrano, 1989). Th ...
doc Lecuter and chapter notes
... flood into a cell that’s been depolarized and thereby return its membrane potential to the resting level when calcium channels open, they also stimulate the production of certain enzymes, which causes some other changes to the cell inhibitory postsynaptic potential (IPSP): the postsynaptic potenti ...
... flood into a cell that’s been depolarized and thereby return its membrane potential to the resting level when calcium channels open, they also stimulate the production of certain enzymes, which causes some other changes to the cell inhibitory postsynaptic potential (IPSP): the postsynaptic potenti ...
Full-Text PDF
... specific SS. This plays an important role as the consensus sequences that make up the 51 SS, 31 SS and BPS are degenerate in higher eukaryotes where alternative splicing is predominant [5]. This also results in SS alone not being capable of efficiently directing spliceosomal assembly. SR and hnRNP p ...
... specific SS. This plays an important role as the consensus sequences that make up the 51 SS, 31 SS and BPS are degenerate in higher eukaryotes where alternative splicing is predominant [5]. This also results in SS alone not being capable of efficiently directing spliceosomal assembly. SR and hnRNP p ...
Document
... clustered at the tip of the spiny anteater’s snout. The researchers made this discovery by exposing small areas of (5) the snout to extremely weak electrical fields and recording the transmission of resulting nervous activity to the brain. While it is true that tactile receptors, another kind of sen ...
... clustered at the tip of the spiny anteater’s snout. The researchers made this discovery by exposing small areas of (5) the snout to extremely weak electrical fields and recording the transmission of resulting nervous activity to the brain. While it is true that tactile receptors, another kind of sen ...
Beating the Heat - University of Colorado Boulder
... shock elements) located in the promoters of genes that are upregulated in response to heat shock. Studies of the activation of heat shock-responsive genes have been instrumental in defining fundamental principles of transcriptional regulation that are applicable to many genes. While this process has ...
... shock elements) located in the promoters of genes that are upregulated in response to heat shock. Studies of the activation of heat shock-responsive genes have been instrumental in defining fundamental principles of transcriptional regulation that are applicable to many genes. While this process has ...
Defining the essential functional regions of the nucleoporin Nup145p
... by 12 hours, almost all of the cells showed nuclear accumulation (Fabre et al., 1994). Inhibition of protein import into the nucleus lagged behind this RNA export defect. These results suggest that Nup145p has a primary role in RNA export. However, because the experimental strategy requiring Nup145p ...
... by 12 hours, almost all of the cells showed nuclear accumulation (Fabre et al., 1994). Inhibition of protein import into the nucleus lagged behind this RNA export defect. These results suggest that Nup145p has a primary role in RNA export. However, because the experimental strategy requiring Nup145p ...
PROTEINS IN NUCLEOCYTOPLASMIC
... present. In the light of this synchrony, the remaining 19 undivided amebae were considered to have been in a late part of the G2 stage at the time of nuclear isolations. All nuclei were isolated in a spermidine-triton solution (4). T h e mean radioactive protein content of these 19 G2 nuclei was 413 ...
... present. In the light of this synchrony, the remaining 19 undivided amebae were considered to have been in a late part of the G2 stage at the time of nuclear isolations. All nuclei were isolated in a spermidine-triton solution (4). T h e mean radioactive protein content of these 19 G2 nuclei was 413 ...
AtLSG1-2 Regulates Leaf Growth by Affecting Cell Proliferation and
... the ploidy distribution by flow cytometry in the first pair of wild-type and atlsg1-2 mutant leaves. Leaf samples were collected during cell division, cell expansion, and maturation phases. As shown in Figure 4, the 2C population decreased more slowly in atlsg1-2 mutants than in wild-type leaves, wh ...
... the ploidy distribution by flow cytometry in the first pair of wild-type and atlsg1-2 mutant leaves. Leaf samples were collected during cell division, cell expansion, and maturation phases. As shown in Figure 4, the 2C population decreased more slowly in atlsg1-2 mutants than in wild-type leaves, wh ...
Early steps in cold sensing by plant cells: the role of actin
... levels for the replacement histone H3.2 protein and for the putative L5 ribosomal protein from alfalfa were determined. The H3.2 (Robertson et al., 1996) and L5 (Asemota et al., 1994) transcripts are constitutively expressed in alfalfa. Both the L5 and H3.2 transcript levels, which are not detectabl ...
... levels for the replacement histone H3.2 protein and for the putative L5 ribosomal protein from alfalfa were determined. The H3.2 (Robertson et al., 1996) and L5 (Asemota et al., 1994) transcripts are constitutively expressed in alfalfa. Both the L5 and H3.2 transcript levels, which are not detectabl ...
Minimally invasive determination of mRNA
... were relaxed by 20% (0.036 and 0.24, respectively). At short-times scales (dwell times j shorter or equal to 256 ms), the autocorrelation function is computed from linearly distributed dwell times j. Consequently, the variance of the residuals at these time scales should be proportional to ( ...
... were relaxed by 20% (0.036 and 0.24, respectively). At short-times scales (dwell times j shorter or equal to 256 ms), the autocorrelation function is computed from linearly distributed dwell times j. Consequently, the variance of the residuals at these time scales should be proportional to ( ...
A novel live cell assay to measure diacylglycerol lipase α activity
... Diacylglycerol lipase α (DAGLα) hydrolyses DAG to generate the principal endocannabinoid (eCB) 2-arachidonoylglycerol (2-AG) in the central nervous system. DAGLα dependent cannabinoid (CB) signalling has been implicated in numerous processes including axonal growth and guidance, adult neurogenesis a ...
... Diacylglycerol lipase α (DAGLα) hydrolyses DAG to generate the principal endocannabinoid (eCB) 2-arachidonoylglycerol (2-AG) in the central nervous system. DAGLα dependent cannabinoid (CB) signalling has been implicated in numerous processes including axonal growth and guidance, adult neurogenesis a ...
review cell division from a genetic perspective
... synthesis of specific gene products. It is of considerable interest to inquire therefore whether the gene-controlled steps that are identified by the thermolabile cell cycle mutations are organized into causal sequences. Two strategies exist for determining these sequences. The less precise method ( ...
... synthesis of specific gene products. It is of considerable interest to inquire therefore whether the gene-controlled steps that are identified by the thermolabile cell cycle mutations are organized into causal sequences. Two strategies exist for determining these sequences. The less precise method ( ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.