Chemical Effectors of Plant Endocytosis and Endomembrane
... vesicles, and partially of MVB fragments (Satiat-Jeunemaitre et al. 1996; Merigout et al. 2002). To better elucidate the highly specific trafficking routes supported by different endomembrane compartments, including responses to either environmental stimuli or developmental signals, it is important ...
... vesicles, and partially of MVB fragments (Satiat-Jeunemaitre et al. 1996; Merigout et al. 2002). To better elucidate the highly specific trafficking routes supported by different endomembrane compartments, including responses to either environmental stimuli or developmental signals, it is important ...
The Sec61p Complex Mediates the Integration of a Membrane
... or TM sequence is inserted into the channel (for review, see Matlack et al., 1998). In the case of a signal sequence, the hydrophobic segment binds in an NcytClum (cyt, cytosol; lum, lumenal) orientation to a specific site at the interface between the channel and lipid formed by both the Sec61p comp ...
... or TM sequence is inserted into the channel (for review, see Matlack et al., 1998). In the case of a signal sequence, the hydrophobic segment binds in an NcytClum (cyt, cytosol; lum, lumenal) orientation to a specific site at the interface between the channel and lipid formed by both the Sec61p comp ...
2 Biogenesis and the regulation of the maturation of miRNAs
... receptor which associates with the p68 and p72 helicases [16]. It may be that these RNA helicases act as the scaffold for recruiting factors to enhance the processing of specific pri-miRNAs. RNA-binding proteins such as KHSRP (KH-type splicing regulatory protein) can also regulate pri-miRNA processi ...
... receptor which associates with the p68 and p72 helicases [16]. It may be that these RNA helicases act as the scaffold for recruiting factors to enhance the processing of specific pri-miRNAs. RNA-binding proteins such as KHSRP (KH-type splicing regulatory protein) can also regulate pri-miRNA processi ...
the pdf - p53 WEB SITE
... antibodies also reacted with two dierent mutant p53 proteins, p53-Y220C and p53-R249S, expressed in Huh-7 and Mahlavu cells, respectively. p53-deleted Hep3B cells were used as a negative control (Hsu et al., 1993). Interestingly, 9E4 reacted with three antigens in these p53-de®cient cells, as well ...
... antibodies also reacted with two dierent mutant p53 proteins, p53-Y220C and p53-R249S, expressed in Huh-7 and Mahlavu cells, respectively. p53-deleted Hep3B cells were used as a negative control (Hsu et al., 1993). Interestingly, 9E4 reacted with three antigens in these p53-de®cient cells, as well ...
Two Light-dependent Conductances in Lima Rhabdomeric
... Lima photoreceptors with the whole-cell clamp technique. Light stimulation from a holding voltage near the cell's resting potential evokes a transient inward current graded with light intensity, accompanied by an increase in membrane conductance. While the photocurrent elicited by dim flashes decays ...
... Lima photoreceptors with the whole-cell clamp technique. Light stimulation from a holding voltage near the cell's resting potential evokes a transient inward current graded with light intensity, accompanied by an increase in membrane conductance. While the photocurrent elicited by dim flashes decays ...
The functional interaction of accessory proteins and voltage
... C. The yeast strain used expresses two reporter genes. The LexA binding sites are upstream of these two genes, so that their expression depends on the binding of the hybrid bait protein, and the AD-cDNA fusion protein, that has bound with the bait. The following proteins that associate with neuronal ...
... C. The yeast strain used expresses two reporter genes. The LexA binding sites are upstream of these two genes, so that their expression depends on the binding of the hybrid bait protein, and the AD-cDNA fusion protein, that has bound with the bait. The following proteins that associate with neuronal ...
Exploring the Effects of Human Cytomegalovirus Infection on Host
... latently infect a majority of the world’s population. Though infections are usually minor, HCMV can cause serious problems in the immunocompromised and is a leading cause of birth defects. When HCMV infects a human cell, it effectively turns the cell into a “virus-producing factory”, taking control ...
... latently infect a majority of the world’s population. Though infections are usually minor, HCMV can cause serious problems in the immunocompromised and is a leading cause of birth defects. When HCMV infects a human cell, it effectively turns the cell into a “virus-producing factory”, taking control ...
The social behaviours of bacterial pathogens
... the lungs of people with CF, where they are associated with high morbidity and mortality.13,39 Burkholderia cenocepacia has been shown to up-regulate the production of virulence determinants in response to AHLs produced by P. aeruginosa, although this does not appear to happen the other way round. T ...
... the lungs of people with CF, where they are associated with high morbidity and mortality.13,39 Burkholderia cenocepacia has been shown to up-regulate the production of virulence determinants in response to AHLs produced by P. aeruginosa, although this does not appear to happen the other way round. T ...
... modify the structure of proteins, and thus to regulate their activity. Reversible phosphorylation, i.e. the addition and removal of a phosphate group, is one of the most important ways for organisms to change the structure and activity of a protein after translation. Proteins are phosphorylated thro ...
SHAPE CONTROL IN THE HUMAN RED CELL
... by ATP-depletion, parallel conversion of PI-PP and phosphatidic acid to phosphatidylinositol (PI) and diacylglycerol, respectively. Their results suggest that metabolic crenation may be caused by a decrease in area of the inner leaflet in accordance with the bilayer-couple hypothesis. A different me ...
... by ATP-depletion, parallel conversion of PI-PP and phosphatidic acid to phosphatidylinositol (PI) and diacylglycerol, respectively. Their results suggest that metabolic crenation may be caused by a decrease in area of the inner leaflet in accordance with the bilayer-couple hypothesis. A different me ...
Understanding Hyaluronan-Protein Interactions
... Introduction Hyaluronan has diverse biological roles in vertebrates. For instance, it acts as a vital structural component of connective tissues,a forms loose hydrated matrices that allow cells to divide and migrate (for example during development),b mediates immune cell adhesion,c and activates int ...
... Introduction Hyaluronan has diverse biological roles in vertebrates. For instance, it acts as a vital structural component of connective tissues,a forms loose hydrated matrices that allow cells to divide and migrate (for example during development),b mediates immune cell adhesion,c and activates int ...
Constructing a Plant Cell. The Genetic Control of Root Hair
... Features of the Cell Specification Mechanism ...
... Features of the Cell Specification Mechanism ...
Yeast longevity and aging—the mitochondrial connection
... for stem cell aging. The renewal of many tissues requires the function of stem cells. This renewal is critical for maintenance of function as the organism ages. However, it is essential that the cells that the stem cells produce are pristine and possess full functional ability. Our studies show that ...
... for stem cell aging. The renewal of many tissues requires the function of stem cells. This renewal is critical for maintenance of function as the organism ages. However, it is essential that the cells that the stem cells produce are pristine and possess full functional ability. Our studies show that ...
Amassin, an olfactomedin protein, mediates the massive
... same prediction criteria a two -strand segment in the NH2terminal region (residues 39–59) is predicted (Fig. 9 B). The all COOH-terminal half containing the OLF domain is in contrast to the NH2-terminal half of amassin that is predicted to contain -helical coiled-coils from residues 75– 108 and ...
... same prediction criteria a two -strand segment in the NH2terminal region (residues 39–59) is predicted (Fig. 9 B). The all COOH-terminal half containing the OLF domain is in contrast to the NH2-terminal half of amassin that is predicted to contain -helical coiled-coils from residues 75– 108 and ...
Association of CAD, a multifunctional protein involved in pyrimidine
... transfected with or without FLAG-mLST8 vector was subjected to immunoprecipitation with the anti-FLAG antibody, and the proteins eluted from resin with the FLAG peptide were visualized by silver staining after SDS-PAGE. FLAG-mLST8, mTOR, and the proteins recovered from the immunoprecipitate (No.1 to ...
... transfected with or without FLAG-mLST8 vector was subjected to immunoprecipitation with the anti-FLAG antibody, and the proteins eluted from resin with the FLAG peptide were visualized by silver staining after SDS-PAGE. FLAG-mLST8, mTOR, and the proteins recovered from the immunoprecipitate (No.1 to ...
114 - University of Oxford
... PSM suggests that the segmentation clock could control somitogenesis by modulating their signalling during segmentation. Recent studies by McGrew et al. (1998) and Forsberg et al. (1998) have shown that lunatic fringe (l-fng) gene expression resembles the expression of c-hairy-1 in PSM. In fact, the ...
... PSM suggests that the segmentation clock could control somitogenesis by modulating their signalling during segmentation. Recent studies by McGrew et al. (1998) and Forsberg et al. (1998) have shown that lunatic fringe (l-fng) gene expression resembles the expression of c-hairy-1 in PSM. In fact, the ...
Folliculin directs the formation of a Rab34–RILP
... with velocities over 1 lm/s (Fig 2Aii and Movie EV1 zoom panels). We also noted FLCN-GFP association with dynamic tubules, that co-labelled weakly or not at all with Lysotracker-Red, whose tips moved at speeds of up to 0.6 lm/s and emanated from larger perinuclear FLCN-GFP-positive compartments (Fig ...
... with velocities over 1 lm/s (Fig 2Aii and Movie EV1 zoom panels). We also noted FLCN-GFP association with dynamic tubules, that co-labelled weakly or not at all with Lysotracker-Red, whose tips moved at speeds of up to 0.6 lm/s and emanated from larger perinuclear FLCN-GFP-positive compartments (Fig ...
Interacting specificity of a histidine kinase and its cognate response
... formed to generate PrrB–DevS chimeric proteins. Two rounds of PCR were carried out using pfu polymerase. The plasmids pUI1643 and pBSC were used as the templates for amplification of portions of prrB and devS, respectively. Two primary PCR reactions were performed with the primers PrrBc(BamHI)+ and ...
... formed to generate PrrB–DevS chimeric proteins. Two rounds of PCR were carried out using pfu polymerase. The plasmids pUI1643 and pBSC were used as the templates for amplification of portions of prrB and devS, respectively. Two primary PCR reactions were performed with the primers PrrBc(BamHI)+ and ...
GATA-2 functions downstream of BMPs and CaM KIV in ectodermal
... progenitors, called EryP-CFC, which give rise to large primitive erythroid cells expressing embryonic and adult globin (Palis et al., 1999; Wong et al., 1986). In contrast, burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) progenitors give rise to small, definitive red b ...
... progenitors, called EryP-CFC, which give rise to large primitive erythroid cells expressing embryonic and adult globin (Palis et al., 1999; Wong et al., 1986). In contrast, burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) progenitors give rise to small, definitive red b ...
![A22254 Touch [version 2.0 ].](http://s1.studyres.com/store/data/015818027_1-1fa81e941fb4f1ccea189d2b012bbb09-300x300.png)
A22254 Touch [version 2.0 ].
... cation channels in the sensory nerve ending. Mechanical stimulation deforms the receptor protein, thus opening stretch-sensitive ion channels, and increasing Na+ and Ca2+ conductance. The resulting inward current through these channels produces a local depolarization of the nerve or receptor cell ca ...
... cation channels in the sensory nerve ending. Mechanical stimulation deforms the receptor protein, thus opening stretch-sensitive ion channels, and increasing Na+ and Ca2+ conductance. The resulting inward current through these channels produces a local depolarization of the nerve or receptor cell ca ...
The Ubiquitin System for Protein Degradation and Some of Its Roles
... episodes from these times. The fractionation of reticulocyte lysates into fractions 1 and 2 was based on a trick that I learned from Mager in the purification of enzymes of purine nucleotide metabolism from erythrocytes. Hemoglobin constitutes about 80–90 % of the total protein of erythrocytes and r ...
... episodes from these times. The fractionation of reticulocyte lysates into fractions 1 and 2 was based on a trick that I learned from Mager in the purification of enzymes of purine nucleotide metabolism from erythrocytes. Hemoglobin constitutes about 80–90 % of the total protein of erythrocytes and r ...
CYTOKINESIS IN HIGHER PLANTS
... tracer FM4-64 makes the latter possibility less likely as both Golgi stacks and cell plate are labeled only 30–60 min after uptake of the tracer (10). The machinery involved in the formation of cytokinetic vesicles has not been identified. However, the following components may be required, by analogy ...
... tracer FM4-64 makes the latter possibility less likely as both Golgi stacks and cell plate are labeled only 30–60 min after uptake of the tracer (10). The machinery involved in the formation of cytokinetic vesicles has not been identified. However, the following components may be required, by analogy ...
Introduction and review of Matlab
... neurotransmitters open sodium channels, and sodium ions move in. 5. If sufficient excitatory neurotransmitter binds to receptors, an action potential is produced in the postsynaptic membrane and travels along the axon of the second neuron. 6. To prevent continuous stimulation or inhibition of the po ...
... neurotransmitters open sodium channels, and sodium ions move in. 5. If sufficient excitatory neurotransmitter binds to receptors, an action potential is produced in the postsynaptic membrane and travels along the axon of the second neuron. 6. To prevent continuous stimulation or inhibition of the po ...
activator
... binding to the operator and blocking RNA polymerase • The repressor is the product of a separate regulatory gene 調節基因 ...
... binding to the operator and blocking RNA polymerase • The repressor is the product of a separate regulatory gene 調節基因 ...
action potential — epilepsy
... huge voltage changes at the membrane. Their number is tiny compared to the total number of ions found in even a very small compartment of adjacent cytoplasm or extracellular fluid. Because of this, many, many action potentials can be generated before the concentration gradient “runs down.” As an act ...
... huge voltage changes at the membrane. Their number is tiny compared to the total number of ions found in even a very small compartment of adjacent cytoplasm or extracellular fluid. Because of this, many, many action potentials can be generated before the concentration gradient “runs down.” As an act ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.