Inhibition of Phorbol Ester-Induced Monocytic
... gene shares homology with other tyrosine kinase-encoding protooncogenes.” Moreover, the c-fms product is identical to the CSF-1 receptor.’ These findings have suggested that CSF-1 is capable of regulating monocyte functions by an autocrine mechanism. The c-fms transcripts become detectable a t 12 to ...
... gene shares homology with other tyrosine kinase-encoding protooncogenes.” Moreover, the c-fms product is identical to the CSF-1 receptor.’ These findings have suggested that CSF-1 is capable of regulating monocyte functions by an autocrine mechanism. The c-fms transcripts become detectable a t 12 to ...
Genetically encoded phenyl azide photochemistry drives
... modulate inherent protein function is fast becoming an important tool in the biosciences as a means to precisely control protein activity with high temporal and spatial resolution not achievable through classical transcriptional control.1–3 Existing approaches to genetically encode protein photocont ...
... modulate inherent protein function is fast becoming an important tool in the biosciences as a means to precisely control protein activity with high temporal and spatial resolution not achievable through classical transcriptional control.1–3 Existing approaches to genetically encode protein photocont ...
Evolutionary Considerations of Neurotransmitters in Microbial, Plant
... 2002; Ekici et al. 2006). Fernández et al. (2006) summarized the data on the histamine content as toxicant in food. Histamine poisoning is the most common food borne problem caused by biogenic amines. At non-toxic doses, this histamine can cause intolerance symptoms such as diarrhea, hypotension, he ...
... 2002; Ekici et al. 2006). Fernández et al. (2006) summarized the data on the histamine content as toxicant in food. Histamine poisoning is the most common food borne problem caused by biogenic amines. At non-toxic doses, this histamine can cause intolerance symptoms such as diarrhea, hypotension, he ...
Directional Gravity Sensing in Gravitropism
... conversion, or transmission, process after susception of the directional change of gravity. Numerous historical studies involving various experimental systems using various species have led to several appealing and plausible models (57, 92, 102). The endoplasmic reticulum (ER) is thought to be invol ...
... conversion, or transmission, process after susception of the directional change of gravity. Numerous historical studies involving various experimental systems using various species have led to several appealing and plausible models (57, 92, 102). The endoplasmic reticulum (ER) is thought to be invol ...
The Development of Novel Approaches to the Identification of
... including within the test configuration an exogenous metabolising system. ...
... including within the test configuration an exogenous metabolising system. ...
the fine structure of the mid-body of the rat
... a ring against the plasma membrane. X 24,000. observations of Hughes and Swann (14), who studied birefringence in the spindle of chick fibroblasts. They observed intense birefringence in the spindle of late telophase which gradually decreased as the cells separated. At its height, the birefringence ...
... a ring against the plasma membrane. X 24,000. observations of Hughes and Swann (14), who studied birefringence in the spindle of chick fibroblasts. They observed intense birefringence in the spindle of late telophase which gradually decreased as the cells separated. At its height, the birefringence ...
Thyroid hormone exerts site-specific effects on SRC
... interact with nuclear cofactors, which are requisite mediators of ligand-dependent transcriptional activation or repression of hormone responsive genes (Glass and Rosenfeld, 2000). Cofactors are believed to remodel local chromatin structure enabling nuclear receptors to activate or repress gene regu ...
... interact with nuclear cofactors, which are requisite mediators of ligand-dependent transcriptional activation or repression of hormone responsive genes (Glass and Rosenfeld, 2000). Cofactors are believed to remodel local chromatin structure enabling nuclear receptors to activate or repress gene regu ...
A molecular framework for the inhibition of
... Ioio et al. 2007). In addition to auxin and cytokinin, other hormones have been recognized as modulating root development, such as gibberellins, ethylene and abscisic acid (ABA). It has recently been shown that gibberellins regulate Arabidopsis root growth by promoting cell proliferation (Achard et ...
... Ioio et al. 2007). In addition to auxin and cytokinin, other hormones have been recognized as modulating root development, such as gibberellins, ethylene and abscisic acid (ABA). It has recently been shown that gibberellins regulate Arabidopsis root growth by promoting cell proliferation (Achard et ...
Interpretation of bafilomycin, pH neutralizing or protease inhibitor
... using these drugs.1 MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that integrates multiple signals such as growth factor abundance with intracellular amino acid and ATP levels to coordinate cell growth and autophagy. MTOR promotes translation in a number of ways including the a ...
... using these drugs.1 MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that integrates multiple signals such as growth factor abundance with intracellular amino acid and ATP levels to coordinate cell growth and autophagy. MTOR promotes translation in a number of ways including the a ...
Evolutionary Considerations of Neurotransmitters in Microbial, Plant
... 2002; Ekici et al. 2006). Fernández et al. (2006) summarized the data on the histamine content as toxicant in food. Histamine poisoning is the most common food borne problem caused by biogenic amines. At non-toxic doses, this histamine can cause intolerance symptoms such as diarrhea, hypotension, he ...
... 2002; Ekici et al. 2006). Fernández et al. (2006) summarized the data on the histamine content as toxicant in food. Histamine poisoning is the most common food borne problem caused by biogenic amines. At non-toxic doses, this histamine can cause intolerance symptoms such as diarrhea, hypotension, he ...
Selective Expression of a Novel Surface Molecule by Human Th2
... D41 effector Th cells can be divided into at least three distinct subsets termed Th1, Th2, and Th0 in both mice and humans, based on the profile of their cytokine production (1– 4). In humans, Th1 cells typically secrete IFN-g and predominantly promote cell-mediated immune responses such as delayed- ...
... D41 effector Th cells can be divided into at least three distinct subsets termed Th1, Th2, and Th0 in both mice and humans, based on the profile of their cytokine production (1– 4). In humans, Th1 cells typically secrete IFN-g and predominantly promote cell-mediated immune responses such as delayed- ...
PDF - International Journal of Medical Sciences
... were polymorphisms existing in two important antigens, MPT64 (4) and PstS1 (5) in clinical M. tuberculosis strains isolated from China. This may be the reason for changes in the antigens produced, which may in turn cause alteration of related functions, thereby allowing immune evasion. Some other pr ...
... were polymorphisms existing in two important antigens, MPT64 (4) and PstS1 (5) in clinical M. tuberculosis strains isolated from China. This may be the reason for changes in the antigens produced, which may in turn cause alteration of related functions, thereby allowing immune evasion. Some other pr ...
Chapter 7A- Cellular Respiration: Glycolysis - TJ
... The below figure introduces the 3 stages of cellular respiration. Label the diagram. Include electron transport chain, pyruvate, mitochondrion, citric acid cycle, glycolysis, cytoplasm, glucose, 2 NADH, 6 NADH, 2 FADH2, 2 ATP, 34 ATP, 38 ATP. ...
... The below figure introduces the 3 stages of cellular respiration. Label the diagram. Include electron transport chain, pyruvate, mitochondrion, citric acid cycle, glycolysis, cytoplasm, glucose, 2 NADH, 6 NADH, 2 FADH2, 2 ATP, 34 ATP, 38 ATP. ...
High pressure effects on protein structure and function
... ties of water surrounding proteins have been visuon hydrophobic contacts. On the other hand, stackalized by other methods. For example, a molecular ing interactions between aromatic rings show negadynamics simulation" has shown that significant tive volume changes and are stabilized by preschanges o ...
... ties of water surrounding proteins have been visuon hydrophobic contacts. On the other hand, stackalized by other methods. For example, a molecular ing interactions between aromatic rings show negadynamics simulation" has shown that significant tive volume changes and are stabilized by preschanges o ...
K-ras modulates the cell cycle via both positive and negative
... Ras proteins play central roles in receptor-mediated signal transduction pathways that control cell proliferation and dierentiation (Khosravi-Far and Der, 1994; Medema and Bos, 1993). Increasing evidence supports the notion that one of the ultimate targets of the ras signaling pathway is the nuclea ...
... Ras proteins play central roles in receptor-mediated signal transduction pathways that control cell proliferation and dierentiation (Khosravi-Far and Der, 1994; Medema and Bos, 1993). Increasing evidence supports the notion that one of the ultimate targets of the ras signaling pathway is the nuclea ...
Phagosome maturation in unicellular eukaryote Paramecium: the
... pathway to ingest bacteria and other food particles. Digestion process starts up upon fusion of phagosomes (i.e. digestive vacuoles at stage II; DV-II) with the primary lysosomes (Allen and Fok 2000) on which we focused our analysis looking for molecular machinery involved in phagolysosome formation ...
... pathway to ingest bacteria and other food particles. Digestion process starts up upon fusion of phagosomes (i.e. digestive vacuoles at stage II; DV-II) with the primary lysosomes (Allen and Fok 2000) on which we focused our analysis looking for molecular machinery involved in phagolysosome formation ...
Article Lateral Gene Transfer and Gene
... complex II and the glycine cleavage system, 2) enzymes associated with anaerobic energy metabolism, including an unusual D-lactate dehydrogenase and acetyl CoA synthase, and 3) a sulfate activation pathway. Intriguingly, components of anaerobic energy metabolism are present in at least two gene copi ...
... complex II and the glycine cleavage system, 2) enzymes associated with anaerobic energy metabolism, including an unusual D-lactate dehydrogenase and acetyl CoA synthase, and 3) a sulfate activation pathway. Intriguingly, components of anaerobic energy metabolism are present in at least two gene copi ...
Evolution of an atypical de-epoxidase for photoprotection in the
... key enzyme responsible for zeaxanthin synthesis from violaxanthin under excess light. Here we show that the Chlorophycean VDE (CVDE) gene from the model green alga Chlamydomonas reinhardtii encodes an atypical VDE. This protein is not homologous to the VDE found in plants and is instead related to a ...
... key enzyme responsible for zeaxanthin synthesis from violaxanthin under excess light. Here we show that the Chlorophycean VDE (CVDE) gene from the model green alga Chlamydomonas reinhardtii encodes an atypical VDE. This protein is not homologous to the VDE found in plants and is instead related to a ...
Targeting Axonal Protein Synthesis in Neuroregeneration and Degeneration REVIEW Jimena Baleriola
... sclerosis (ALS) and spinal muscular atrophy (SMA). For example, ALS-causing mutations in the RNA-binding protein TDP-43 impairs axonal trafficking of mRNA granules to distal axons [41]. Similarly, reduced levels of survival of motor neuron (SMN) decrease axonal mRNA localization and human SMN1 mutat ...
... sclerosis (ALS) and spinal muscular atrophy (SMA). For example, ALS-causing mutations in the RNA-binding protein TDP-43 impairs axonal trafficking of mRNA granules to distal axons [41]. Similarly, reduced levels of survival of motor neuron (SMN) decrease axonal mRNA localization and human SMN1 mutat ...
Cell Cycle in the Fucus Zygote Parallels a Somatic Cell
... embryos. Finally, cell cycle checkpoints of somatic cells differ greatly from those of embryonic cells. Somatic cells display stringent surveillance mechanisms that check the success of various cell cycle events such as DNA replication and the integrity of the spindle, preventing mitosis until accur ...
... embryos. Finally, cell cycle checkpoints of somatic cells differ greatly from those of embryonic cells. Somatic cells display stringent surveillance mechanisms that check the success of various cell cycle events such as DNA replication and the integrity of the spindle, preventing mitosis until accur ...
- Wiley Online Library
... understanding how actin cytoskeleton and its interaction with microtubules are precisely modulated in the growth cone. There are two kinds of cytoskeletal filaments, F-actin and microtubules, in the growth cone. The actin cytoskeleton, composed of actin polymers and a large variety of associated prot ...
... understanding how actin cytoskeleton and its interaction with microtubules are precisely modulated in the growth cone. There are two kinds of cytoskeletal filaments, F-actin and microtubules, in the growth cone. The actin cytoskeleton, composed of actin polymers and a large variety of associated prot ...
Detergent-Insoluble Membrane Compartment CD20 Required for Its
... To determine the membrane orientation of CD20, Abs against known epitopes were generated in rabbits by immunization with OVA-conjugated CD20 N and C region peptides. The resulting antisera, anti-CD20N and anti-CD20C, were affinity purified and tested for specificity before use in membrane orientatio ...
... To determine the membrane orientation of CD20, Abs against known epitopes were generated in rabbits by immunization with OVA-conjugated CD20 N and C region peptides. The resulting antisera, anti-CD20N and anti-CD20C, were affinity purified and tested for specificity before use in membrane orientatio ...
Redox regulation of cysteine
... MnSOD (SOD2; localized to mitochondria) and CuZnSOD, with 2 types of CuZnSOD that are found either intracellularly (SOD1) or extracellularly (SOD3). These enzymes are responsible for the conversion of superoxide to H2O2, although this occurs slowly and spontaneously as well. Although superoxide is a ...
... MnSOD (SOD2; localized to mitochondria) and CuZnSOD, with 2 types of CuZnSOD that are found either intracellularly (SOD1) or extracellularly (SOD3). These enzymes are responsible for the conversion of superoxide to H2O2, although this occurs slowly and spontaneously as well. Although superoxide is a ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.