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The Vestibular System
The Vestibular System

... 2. If a muscle is weakened, a given central signal will be inadequate, and the world will move on the retina. 3. This can be mimicked by spectacles that increase retinal slip. 4. In either case, the brain adjusts the VOR signal so the retinal slip is eliminated. 5. The cerebellum is necessary for bo ...
View PDF - CiteSeerX
View PDF - CiteSeerX

... regulation of steroid hormone and sterol homeostasis. Introduction Steroid hormones are cholesterol derivatives that serve as signaling molecules to coordinate the expression of complex gene programs in higher eukaryotes. These molecules exert their effects by diffusing into cells and interacting wi ...
Cook Dev Cell 2003
Cook Dev Cell 2003

... (A–E) Expression pattern of Prospero in the adult retina (A–D) or pupal retina 72 hr APF (E) (dorsal up, distal right). Costaining of adult retinas with anti-Pros (red, [A]) or anti-Sal (green, [B]) antibodies (B). R7 nuclei are distally placed within the cells, whereas R8 nuclei are proximally loca ...
The tubulin gene family of Paramecium: Characterization and
The tubulin gene family of Paramecium: Characterization and

... are well known and extensive immunocytochemical studies of the post-translational modifications in the various microtubule systems have been reported. However, in order to better understand the biogenesis of these multiple and diverse microtubule arrays, it seemed necessary to characterize the tubul ...
Sarcolemmal cholesterol and caveolin-3 dependence of - AJP
Sarcolemmal cholesterol and caveolin-3 dependence of - AJP

... NaHCO3, and 15 mM glucose equilibrated with 95% O2-5% CO2 for a further 5 h. Cells were untreated or treated with 1 mM M␤CD for 60 min before simulated I/R. LDH activity was assayed using a CytoTox 96 assay kit (Promega) according to the manufacturer’s instructions. Normoxic control cells incubated ...
Cell surface mechanics and the control of cell shape, tissue patterns
Cell surface mechanics and the control of cell shape, tissue patterns

... with the surroundings and, therefore, minimizes its surface energy. Increasing the surface area of the drop requires an energy δE, which is proportional to the area increment δS, such that δE=σδS, in which σ is the surface tension of the liquid. The coefficient σ has the dimension of energy per unit ...
The plant cytoskeleton: its significance in plant
The plant cytoskeleton: its significance in plant

... also co-localize with microtubules in immunofluorescent preparations, ...
Photomorphogenesis, B-Box Transcription Factors
Photomorphogenesis, B-Box Transcription Factors

... consensus motif in the B-box proteins (Holm et al., 2001), thus leaving the RING, coiledcoil, and B-box domains free to interact with other proteins. Magnus brought the COP1-interacting proteins with him when he started his own laboratory at Gothenburg University in 2002, and since then he showed th ...
Correlative Imaging of Fluorescent Proteins in Resin
Correlative Imaging of Fluorescent Proteins in Resin

... plant tissues. Thompson and Wolniak (2008) described the retention of mCitrine fused to an SEplasma membrane protein in glycol methacrylate sections. The fluorescent signal was stable using wide-field microscopy but bleached rapidly under the confocal microscope. To date, cryosections have been the pr ...
Summary - University of Amsterdam
Summary - University of Amsterdam

... Thee presence of glutathione-utilizing enzymes in peroxisomes of various species has been reported. Inn light of the impermeability of the peroxisomal membrane in vivo, this raises the question of how glutathionee is regenerated. As described in chapter 2, peroxisomes of the yeast Saccharomyces cere ...
Overexpression of a truncated cyclin B gene arrests Dictyostelium
Overexpression of a truncated cyclin B gene arrests Dictyostelium

... Total RNA was extracted from cells by the acid guanidinium thiocyanate method (Chomczynski and Sacchi, 1987). In order to reduce the hybridization background caused by the presence of the high copy number of the transgene in the transformants, the RNA preparations were resuspended in 500 µl of RES-1 ...
Nervous System I
Nervous System I

... or support neurons. Today we know that they have many other functions, including nourishing neurons and sending and receiving messages. An important part of the nervous system at the cellular level is not a cell at all, but the small space between a neuron and the cell(s) with which it communicates, ...
Type 2 Diabetes
Type 2 Diabetes

... On carbohydrate metabolism.. Reduces rate of release of glucose from the liver by ...
SUPPLEMENTARY INFORMATION TABLE OF CONTENTS: 1
SUPPLEMENTARY INFORMATION TABLE OF CONTENTS: 1

... respect to their snoRNA repertoire. Further work must be done to uncover the rest of the snoRNAs including species specific snoRNAs as well as a targeted search for specific small RNAs such as the SLA1. In addition, a global analysis of genomic cluster of these snoRNAs would be able to answer if the ...
FapR, a Bacterial Transcription Factor Involved in
FapR, a Bacterial Transcription Factor Involved in

... One of the most daunting challenges in biology is elucidating the mechanisms by which cells sense and respond to changes in the biosynthesis of essential building blocks that support a majority of cellular activities. Among the critical metabolic changes that occur during various conditions in all l ...
Advances in improving mammalian cells metabolism for
Advances in improving mammalian cells metabolism for

Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase
Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase

... dependent manner that is associated with diminished patient survival (Ueda et al., 2010; Tao et al., 2013; Nguyen et al., 2010; Notarnicola et al., 2012; Witkiewicz et al., 2008; Zaytseva et al., 2012). This expression–prognosis relationship suggests that FASN plays an important role in affecting tu ...
Assembly of the Light-Harvesting Chlorophyll Antenna in the Green
Assembly of the Light-Harvesting Chlorophyll Antenna in the Green

... the chloroplast. It is essential for the incorporation of the peripheral LHCs into the thylakoid membrane of photosynthesis (Bellafiore et al., 2002). The ALB3.1 protein is also known in Arabidopsis (Arabidopsis thaliana) but its function appears to extend beyond the transmembrane integration of LHC ...
The Biochemistry and Structural Biology of Plant
The Biochemistry and Structural Biology of Plant

... significant features of plant cell wall degrading enzymes is their complex molecular architectures ...
Full Text  - Plant and Cell Physiology
Full Text - Plant and Cell Physiology

... cell wall plays a crucial role in various plant functions such as cell growth, organ formation and defense responses. Cellulose is synthesized by cellulose synthase complexes (CSCs) embedded in the plasma membrane (PM), which comprise the cellulose synthases (CESAs). The abundance and localization o ...
Ghorbaniaghdam (oral)
Ghorbaniaghdam (oral)

... Monoclonal antibody producing Chinese hamster ovary (CHO) cells have been shown to undergo metabolic changes when engineered to produce high titers of recombinant proteins. In this work, we have studied the distinct metabolism of CHO cell clones harboring an efficient inducible expression system, ba ...
May 21, 04copy.doc
May 21, 04copy.doc

... lasting disinhibition in neurons of deprived barrel columns, such as the increase in spontaneous activity, and the decrease in preference for angle of whisker deflection (Simons and Land, 1987). This respecification of receptive fields can also be mapped using markers for neuronal activity such as 2 ...
Latrunculin A Induced Perturbation of the Actin Cytoskeleton
Latrunculin A Induced Perturbation of the Actin Cytoskeleton

... Next, to ensure that we could detect nuclear localized Pap1-GFP, we cultured the Pap1GFP expressing strain to mid-log phase and treated the cells with 0.003% hydrogen peroxide. As expected Pap1-GFP could be detected in the nucleus within 15 minutes of hydrogen peroxide exposure, but was excluded fro ...
Cells without the calnexin/calreticulin central region are viable
Cells without the calnexin/calreticulin central region are viable

... of the glycoprotein acid phosphatase, independently of glucose trimming and reglucosylation by GT (Jannatipour et al., 1998). Thus, in spite of the essentiality of Cnx1p for fission yeast viability, the glucose trimming and reglucosylation cycle do not appear to be indispensable for protein folding ...
Full-Text PDF
Full-Text PDF

... Many studies on a molecular and a cellular scale have allowed a better understanding of the mechanisms involved in the establishment of the different tissues during plant development. Tissues grow in a well-organized fashion which shapes the plant’s final structure. Plant growth is the result of two ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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